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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1988 2
1989 7
1990 5
1991 10
1992 10
1993 12
1994 9
1995 7
1996 16
1997 8
1998 12
1999 11
2000 18
2001 17
2002 31
2003 12
2004 13
2005 25
2006 29
2007 26
2008 26
2009 28
2010 24
2011 22
2012 30
2013 29
2014 25
2015 25
2016 26
2017 18
2018 20
2019 31
2020 24
2021 19
2022 5
2023 5
2024 1

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578 results

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3 articles found by citation matching

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Page 1
Myeloid-Cell-Specific IL-6 Signaling Promotes MicroRNA-223-Enriched Exosome Production to Attenuate NAFLD-Associated Fibrosis.
Hou X, Yin S, Ren R, Liu S, Yong L, Liu Y, Li Y, Zheng MH, Kunos G, Gao B, Wang H. Hou X, et al. Hepatology. 2021 Jul;74(1):116-132. doi: 10.1002/hep.31658. Epub 2021 Apr 27. Hepatology. 2021. PMID: 33236445 Free PMC article.
Mechanistically, the increased LF in HFD-fed, myeloid-specific Il6ra KO mice was attributable to the reduction of antifibrotic miR-223 and subsequent up-regulation of the miR-223 target gene, transcriptional activator with PDZ-binding motif (TAZ), a well-known facto …
Mechanistically, the increased LF in HFD-fed, myeloid-specific Il6ra KO mice was attributable to the reduction of antifibrotic miR-223 and s …
IL-6 translation is a therapeutic target of human cytokine release syndrome.
Yang Y, Zhang Y, Xing X, Xu G, Lin X, Wang Y, Chen M, Wang C, Zhang B, Han W, Hu X. Yang Y, et al. J Exp Med. 2023 Nov 6;220(11):e20230577. doi: 10.1084/jem.20230577. Epub 2023 Aug 16. J Exp Med. 2023. PMID: 37584653 Free PMC article.
Here, an accidental clinical observation raised the possibility that metoprolol, an FDA-approved beta1 adrenergic receptor blocker widely used for cardiovascular conditions, may alleviate CAR T-induced CRS. Metoprolol effectively blocked IL-6 production in human monocyt
Here, an accidental clinical observation raised the possibility that metoprolol, an FDA-approved beta1 adrenergic receptor blocker widely us …
MCT-1/miR-34a/IL-6/IL-6R signaling axis promotes EMT progression, cancer stemness and M2 macrophage polarization in triple-negative breast cancer.
Weng YS, Tseng HY, Chen YA, Shen PC, Al Haq AT, Chen LM, Tung YC, Hsu HL. Weng YS, et al. Mol Cancer. 2019 Mar 18;18(1):42. doi: 10.1186/s12943-019-0988-0. Mol Cancer. 2019. PMID: 30885232 Free PMC article.
RESULTS: We found that the oncogene Multiple Copies in T-cell Malignancy 1 (MCT-1/MCTS1) expression is a new poor-prognosis marker in patients with aggressive breast cancers. ...MCT-1 stimulated interleukin-6 (IL-6) secretion that promoted monocytic TH …
RESULTS: We found that the oncogene Multiple Copies in T-cell Malignancy 1 (MCT-1/MCTS1) expression is a new poor-prognosis marker in …
Regulation of interleukin-6 receptor expression in human monocytes and hepatocytes.
Bauer J, Lengyel G, Bauer TM, Acs G, Gerok W. Bauer J, et al. FEBS Lett. 1989 May 22;249(1):27-30. doi: 10.1016/0014-5793(89)80008-0. FEBS Lett. 1989. PMID: 2498129 Free article.
Human blood monocytes normally express the interleukin-6 receptor. ...Glucocorticoids aso cause a drop in monocytic interleukin-6 receptor mRNA levels. We also found interleukin-6 receptor
Human blood monocytes normally express the interleukin-6 receptor. ...Glucocorticoids aso cause a
Regulation of interleukin-6 receptor expression by interleukin-6 in human monocytes--a re-examination.
Schoester M, Heinrich PC, Graeve L. Schoester M, et al. FEBS Lett. 1994 May 30;345(2-3):131-4. doi: 10.1016/0014-5793(94)00416-1. FEBS Lett. 1994. PMID: 8200444 Free article.
We have studied the expression and regulation of the interleukin-6 receptor (gp80) and its signal transducer gp130 in primary human blood monocytes. Here, we show that freshly isolated human monocytes express m …
We have studied the expression and regulation of the interleukin-6 receptor (gp80) and its signal transdu …
Regulation of interleukin 6 receptor expression in human monocytes and monocyte-derived macrophages. Comparison with the expression in human hepatocytes.
Bauer J, Bauer TM, Kalb T, Taga T, Lengyel G, Hirano T, Kishimoto T, Acs G, Mayer L, Gerok W. Bauer J, et al. J Exp Med. 1989 Nov 1;170(5):1537-49. doi: 10.1084/jem.170.5.1537. J Exp Med. 1989. PMID: 2809509 Free PMC article.
Stimulation of monocytes by endotoxin or IL-1 causes a rapid downregulation of IL-6-R mRNA levels and a concomitant enhancement of IL-6 mRNA expression. ...A gradual decrease of IL-6-R mRNA levels was observed along in vitro maturation of monocytes into macro …
Stimulation of monocytes by endotoxin or IL-1 causes a rapid downregulation of IL-6-R mRNA levels and a concomitant enhancement of IL …
Role of the IL-6-Receptor expression in CD14+ monocytes in modulating sleep in patients with bipolar disorder.
Ritter P, Brandt M, Schrempf W, Brezan F, Krupka A, Storch A, Sauer C, Pfennig A, Bauer M, Soltmann B. Ritter P, et al. J Affect Disord. 2018 Oct 15;239:152-160. doi: 10.1016/j.jad.2018.06.037. Epub 2018 Jun 25. J Affect Disord. 2018. PMID: 30014955
Since elevations in IL-6R have repeatedly been demonstrated in bipolar disorder the association of sleep quality and architecture with levels of mRNA coding for IL-6R in monocytes was to be tested. METHODS: Euthymic patients with bipolar disorder (n = 24) and healthy co
Since elevations in IL-6R have repeatedly been demonstrated in bipolar disorder the association of sleep quality and architecture with level …
HSV-1 Modulates IL-6 Receptor Expression on Human Dendritic Cells.
Birzer A, Krawczyk A, Draßner C, Kuhnt C, Mühl-Zürbes P, Heilingloh CS, Steinkasserer A, Popella L. Birzer A, et al. Front Immunol. 2020 Aug 26;11:1970. doi: 10.3389/fimmu.2020.01970. eCollection 2020. Front Immunol. 2020. PMID: 32983130 Free PMC article.
Here we demonstrate that HSV-1 infection influences the IL-6 receptor (IL6R) expression both on protein and mRNA levels in/on human monocyte-derived mature DCs (mDCs). Surprisingly, reduced IL6R expression levels were also observed on uninfected bystan …
Here we demonstrate that HSV-1 infection influences the IL-6 receptor (IL6R) expression both on protein and mRNA levels in/on huma
ApoE production in human monocytes and its regulation by inflammatory cytokines.
Braesch-Andersen S, Paulie S, Smedman C, Mia S, Kumagai-Braesch M. Braesch-Andersen S, et al. PLoS One. 2013 Nov 14;8(11):e79908. doi: 10.1371/journal.pone.0079908. eCollection 2013. PLoS One. 2013. PMID: 24244577 Free PMC article.
In PBMC, apoE secretion was restricted to monocytes with classical (CD14(++)CD16(-)) and intermediate (CD14(+)CD16(+)) monocytes being the main producers. ...Other cytokines tested, IL-2, IL-4, IL-12, IL-13, IL-17A and IL-23, had no inhibitory effect on apoE product …
In PBMC, apoE secretion was restricted to monocytes with classical (CD14(++)CD16(-)) and intermediate (CD14(+)CD16(+)) monocytes
Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling.
Flynn CM, Garbers Y, Lokau J, Wesch D, Schulte DM, Laudes M, Lieb W, Aparicio-Siegmund S, Garbers C. Flynn CM, et al. Sci Rep. 2019 May 13;9(1):7306. doi: 10.1038/s41598-019-43617-5. Sci Rep. 2019. PMID: 31086276 Free PMC article.
Here, we show that activation of Toll-like receptor 2 (TLR2) on primary human peripheral blood mononuclear cells (PBMCs) and on the monocytic cell line THP-1 induces expression and secretion of IL-6 and the generation of sIL-6R. We show by flow cytometry that …
Here, we show that activation of Toll-like receptor 2 (TLR2) on primary human peripheral blood mononuclear cells (PBMCs) and on the …
578 results