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Retinal pigment epithelial phagocytosis and metabolism differ from those of macrophages.
Irschick EU, Sgonc R, Böck G, Wolf H, Fuchs D, Nussbaumer W, Göttinger W, Huemer HP. Irschick EU, et al. Ophthalmic Res. 2004 Jul-Aug;36(4):200-10. doi: 10.1159/000078778. Ophthalmic Res. 2004. PMID: 15292658
The purpose of this study is to compare primary human retinal pigment epithelium (RPE) cells with respect to particle uptake and further processing steps with immunological phagocytes for a better understanding of the possible role of RPE cells in triggering autoimm …
The purpose of this study is to compare primary human retinal pigment epithelium (RPE) cells with respect to particle uptake a …
Opposite Roles of MerTK Ligands Gas6 and Protein S During Retinal Phagocytosis.
Nandrot EF. Nandrot EF. Adv Exp Med Biol. 2018;1074:577-583. doi: 10.1007/978-3-319-75402-4_70. Adv Exp Med Biol. 2018. PMID: 29721990
MerTK is required for photoreceptor outer segment (POS) phagocytosis by retinal pigment epithelial (RPE) cells, a diurnal function essential for vision maintenance. ...Indeed, with opposite effects on RPE phagocytosis and changes in their expres …
MerTK is required for photoreceptor outer segment (POS) phagocytosis by retinal pigment epithelial (RPE) cells, …
Clearance of autophagy-associated dying retinal pigment epithelial cells - a possible source for inflammation in age-related macular degeneration.
Szatmári-Tóth M, Kristóf E, Veréb Z, Akhtar S, Facskó A, Fésüs L, Kauppinen A, Kaarniranta K, Petrovski G. Szatmári-Tóth M, et al. Cell Death Dis. 2016 Sep 8;7(9):e2367. doi: 10.1038/cddis.2016.133. Cell Death Dis. 2016. PMID: 27607582 Free PMC article.
Retinal pigment epithelial (RPE) cells can undergo different forms of cell death, including autophagy-associated cell death during age-related macular degeneration (AMD). Failure of macrophages or dendritic cells (DCs) to engulf the different
Retinal pigment epithelial (RPE) cells can undergo different forms of cell death, including autophagy-associated
[Pathophysiology of macular diseases--morphology and function].
Iida T. Iida T. Nippon Ganka Gakkai Zasshi. 2011 Mar;115(3):238-74; discussion 275. Nippon Ganka Gakkai Zasshi. 2011. PMID: 21476310 Review. Japanese.
Ophthalmic fundus imaging plays an important role in the advances in the pathophysiology of retinal diseases. Using fundus imaging, we studied morphological changes in the choroid, subretinal pathophysiology and photoreceptor and retinal pigment epithelial
Ophthalmic fundus imaging plays an important role in the advances in the pathophysiology of retinal diseases. Using fundus imaging, w …
The retinal-pigment epithelial interface.
Foulds WS. Foulds WS. Br J Ophthalmol. 1979 Feb;63(2):71-84. doi: 10.1136/bjo.63.2.71. Br J Ophthalmol. 1979. PMID: 427074 Free PMC article.
The pluripotential role of the pigment epithelium is stressed, particularly in relation to the phagocytosis of outer segment material and the ability of this layer to undergo metaplasia into a variety of different cell types. Similarities of all disturbances …
The pluripotential role of the pigment epithelium is stressed, particularly in relation to the phagocytosis of outer segment m …
Clearance of dying ARPE-19 cells by professional and nonprofessional phagocytes in vitro- implications for age-related macular degeneration (AMD).
Petrovski G, Berényi E, Moe MC, Vajas A, Fésüs L, Berta A, Facskó A. Petrovski G, et al. Acta Ophthalmol. 2011 Feb;89(1):e30-4. doi: 10.1111/j.1755-3768.2010.02047.x. Epub 2010 Nov 23. Acta Ophthalmol. 2011. PMID: 21091941 Free article.
PURPOSE: Failure of retinal pigment epithelial (RPE) cells and macrophages to engulf different dying cells in the retina may result in accumulation of debris and development of age-related macular degeneration (AMD). The dynamics and influence o …
PURPOSE: Failure of retinal pigment epithelial (RPE) cells and macrophages to engulf different dying cell …
Morphological characterization of the retinal degeneration in three strains of mice carrying the rd-3 mutation.
Linberg KA, Fariss RN, Heckenlively JR, Farber DB, Fisher SK. Linberg KA, et al. Vis Neurosci. 2005 Nov-Dec;22(6):721-34. doi: 10.1017/S0952523805226044. Vis Neurosci. 2005. PMID: 16469183 Free article.
Retinal development in 3 strains of rd-3/rd-3 mutant mice, previously shown to have different rates of degeneration, was studied using light, electron, and immunofluorescence microscopy. ...Rod opsin is expressed in the developing OS but is redistributed into plasma
Retinal development in 3 strains of rd-3/rd-3 mutant mice, previously shown to have different rates of degeneration, was studi
The C-mer gene is induced by Epstein-Barr virus immediate-early protein BRLF1.
Li Y, Mahajan NP, Webster-Cyriaque J, Bhende P, Hong GK, Earp HS, Kenney S. Li Y, et al. J Virol. 2004 Nov;78(21):11778-85. doi: 10.1128/JVI.78.21.11778-11785.2004. J Virol. 2004. PMID: 15479819 Free PMC article.
C-mer is a receptor tyrosine kinase activated by the ligand Gas6. C-mer is required for phagocytosis of apoptotic debris by monocytes/macrophages and retinal pigment epithelial cells and is capable of producing an antiapoptotic signal. Modulatio …
C-mer is a receptor tyrosine kinase activated by the ligand Gas6. C-mer is required for phagocytosis of apoptotic debris by monocytes …
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