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Reverse signaling through transmembrane TNF confers resistance to lipopolysaccharide in human monocytes and macrophages.
Eissner G, Kirchner S, Lindner H, Kolch W, Janosch P, Grell M, Scheurich P, Andreesen R, Holler E. Eissner G, et al. J Immunol. 2000 Jun 15;164(12):6193-8. doi: 10.4049/jimmunol.164.12.6193. J Immunol. 2000. PMID: 10843670 Free article.
This led to the hypothesis that a reverse signal is transmitted from the TNF receptor on EC to monocytes (MO) via mTNF that prevents the production of soluble apoptotic factors. ...Finally, we show that reverse signaling through mTNF medi …
This led to the hypothesis that a reverse signal is transmitted from the TNF receptor on EC to monocytes (MO) vi …
LPS resistance in monocytic cells caused by reverse signaling through transmembrane TNF (mTNF) is mediated by the MAPK/ERK pathway.
Kirchner S, Boldt S, Kolch W, Haffner S, Kazak S, Janosch P, Holler E, Andreesen R, Eissner G. Kirchner S, et al. J Leukoc Biol. 2004 Feb;75(2):324-31. doi: 10.1189/jlb.0703343. Epub 2003 Nov 11. J Leukoc Biol. 2004. PMID: 14612430
Reverse signaling by mTNF confers resistance to bacterial lipopolysaccharide (LPS). ...Thus, reverse signaling achieves LPS resistance in monocytic cells through interference with key signal-transduction
Reverse signaling by mTNF confers resistance to bacterial lipopolysaccharide (LPS). ...Thus, reverse
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