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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2002 1
2004 4
2005 1
2006 1
2010 3
2011 9
2012 5
2013 2
2014 5
2015 6
2016 1
2017 3
2018 1
2019 1
2020 0
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Regulation of the MIR155 host gene in physiological and pathological processes.
Elton TS, Selemon H, Elton SM, Parinandi NL. Elton TS, et al. Gene. 2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14. Gene. 2013. PMID: 23246696 Review.
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing complex to inhibit gene expression by targeting mRNAs for translation …
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in posttranscriptional gene regulation by a …
The macrophage response towards LPS and its control through the p38(MAPK)-STAT3 axis.
Bode JG, Ehlting C, Häussinger D. Bode JG, et al. Cell Signal. 2012 Jun;24(6):1185-94. doi: 10.1016/j.cellsig.2012.01.018. Epub 2012 Feb 4. Cell Signal. 2012. PMID: 22330073 Review.
The balanced activation of this axis is essential for both induction and propagation of the inflammatory macrophage response as well as for the control of the resolution phase, which is largely driven by IL-10 and sustained STAT3 activation. In this context r …
The balanced activation of this axis is essential for both induction and propagation of the inflammatory macrophage response as well as for …
Role of Stat3 in lipopolysaccharide-induced IL-10 gene expression.
Benkhart EM, Siedlar M, Wedel A, Werner T, Ziegler-Heitbrock HW. Benkhart EM, et al. J Immunol. 2000 Aug 1;165(3):1612-7. doi: 10.4049/jimmunol.165.3.1612. J Immunol. 2000. PMID: 10903771 Free article.
IL-10 is a unique cytokine because it is anti-inflammatory and immunosuppressive. IL-10 is regulated at the level of transcription, but the critical motifs and the relevant transcription factors controlling this gene have remained
IL-10 is a unique cytokine because it is anti-inflammatory and immunosuppressive. IL-10 is regulated at the leve
Role of endogenous IL-10 in LPS-induced STAT3 activation and IL-1 receptor antagonist gene expression.
Carl VS, Gautam JK, Comeau LD, Smith MF Jr. Carl VS, et al. J Leukoc Biol. 2004 Sep;76(3):735-42. doi: 10.1189/jlb.1003526. Epub 2004 Jun 24. J Leukoc Biol. 2004. PMID: 15218058
The regulation of secretory interleukin (IL)-1 receptor antagonist (sIL-1Ra) in response to IL-10 is unique. In contrast to most cytokines, the lipopolysaccharide (LPS)-induced expression of the sIL-1Ra gene is enhanced by c …
The regulation of secretory interleukin (IL)-1 receptor antagonist (sIL-1Ra) in response to IL-10 is unique. In …
S100A8/A9 and S100A9 reduce acute lung injury.
Hiroshima Y, Hsu K, Tedla N, Wong SW, Chow S, Kawaguchi N, Geczy CL. Hiroshima Y, et al. Immunol Cell Biol. 2017 May;95(5):461-472. doi: 10.1038/icb.2017.2. Epub 2017 Jan 11. Immunol Cell Biol. 2017. PMID: 28074060 Free PMC article.
S100 proteins did not significantly induce proinflammatory mediators including TNF-α, interleukin-1β (IL-1β), IL-6 or serum amyloid A3 (SAA3). ...Like S100A8, S100A9 and S100A8/A9 reduced neutrophil influx in acute lung injury provoked by lipopolysa
S100 proteins did not significantly induce proinflammatory mediators including TNF-α, interleukin-1β (IL-1β), IL
Endothelial Cells in the Decidual Bed Are Potential Therapeutic Targets for Preterm Birth Prevention.
Deng W, Yuan J, Cha J, Sun X, Bartos A, Yagita H, Hirota Y, Dey SK. Deng W, et al. Cell Rep. 2019 May 7;27(6):1755-1768.e4. doi: 10.1016/j.celrep.2019.04.049. Cell Rep. 2019. PMID: 31067461 Free PMC article.
Under inflammatory conditions, IL-6 is readily expressed in decidual endothelial cells with signal transducer and activator of transcription 3 (Stat3) phosphorylation in perivascular stromal cells, which then regulates expression of anti-inflammatory …
Under inflammatory conditions, IL-6 is readily expressed in decidual endothelial cells with signal transducer and activator of tra
TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury.
Mittal M, Tiruppathi C, Nepal S, Zhao YY, Grzych D, Soni D, Prockop DJ, Malik AB. Mittal M, et al. Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8151-E8158. doi: 10.1073/pnas.1614935113. Epub 2016 Nov 28. Proc Natl Acad Sci U S A. 2016. PMID: 27911817 Free PMC article.
TSG6 also prevented the expression of proinflammatory proteins (iNOS, IL-6, TNFα, IL-1β, and CXCL1) while increasing the expression of anti-inflammatory proteins (CD206, Chi3l3, IL-4, and IL-10) in macrophages. This shift was assoc …
TSG6 also prevented the expression of proinflammatory proteins (iNOS, IL-6, TNFα, IL-1β, and CXCL1) while increasing th …
Lipopolysaccharide-mediated IL-10 transcriptional regulation requires sequential induction of type I IFNs and IL-27 in macrophages.
Iyer SS, Ghaffari AA, Cheng G. Iyer SS, et al. J Immunol. 2010 Dec 1;185(11):6599-607. doi: 10.4049/jimmunol.1002041. Epub 2010 Nov 1. J Immunol. 2010. PMID: 21041726 Free PMC article.
Dysregulation of IL-10 is associated with a number of autoimmune diseases, and so, understanding the mechanisms by which IL-10 gene expression is regulated remains an important area of study. ...We demonstrate that IL-27 signaling …
Dysregulation of IL-10 is associated with a number of autoimmune diseases, and so, understanding the mechanisms by which IL
Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3K-Akt-GSK3 pathway.
Antoniv TT, Ivashkiv LB. Antoniv TT, et al. Immunology. 2011 Apr;132(4):567-77. doi: 10.1111/j.1365-2567.2010.03402.x. Epub 2011 Jan 24. Immunology. 2011. PMID: 21255011 Free PMC article.
Interleukin-10 (IL-10) is an immunosuppressive cytokine that inhibits inflammatory gene expression. Phosphatidylinositol 3-kinase (PI3K) -mediated signalling regulates inflammatory responses and can induce IL-10 produ
Interleukin-10 (IL-10) is an immunosuppressive cytokine that inhibits inflammatory gene expression
Myeloid-cell protein tyrosine phosphatase-1B deficiency in mice protects against high-fat diet and lipopolysaccharide-induced inflammation, hyperinsulinemia, and endotoxemia through an IL-10 STAT3-dependent mechanism.
Grant L, Shearer KD, Czopek A, Lees EK, Owen C, Agouni A, Workman J, Martin-Granados C, Forrester JV, Wilson HM, Mody N, Delibegovic M. Grant L, et al. Diabetes. 2014 Feb;63(2):456-70. doi: 10.2337/db13-0885. Epub 2013 Nov 1. Diabetes. 2014. PMID: 24186864 Free article.
In vitro, LPS-treated LysM PTP1B bone marrow-derived macrophages (BMDMs) displayed increased interleukin (IL)-10 mRNA expression, with a concomitant decrease in TNF-α mRNA levels. ...HF-fed LysM PTP1B mice had increased basal and LPS-induced
In vitro, LPS-treated LysM PTP1B bone marrow-derived macrophages (BMDMs) displayed increased interleukin (IL)-10 mRNA …
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