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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2002 1
2004 4
2005 1
2006 1
2010 3
2011 9
2012 5
2013 2
2014 5
2015 6
2016 1
2017 3
2018 1
2019 2
2020 2
2021 2
2022 2
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43 results

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Page 1
Regulation of the MIR155 host gene in physiological and pathological processes.
Elton TS, Selemon H, Elton SM, Parinandi NL. Elton TS, et al. Gene. 2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14. Gene. 2013. PMID: 23246696 Review.
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing complex to inhibit gene expression by targeting mRNAs for translation …
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in posttranscriptional gene regulation by a …
Role of Stat3 in lipopolysaccharide-induced IL-10 gene expression.
Benkhart EM, Siedlar M, Wedel A, Werner T, Ziegler-Heitbrock HW. Benkhart EM, et al. J Immunol. 2000 Aug 1;165(3):1612-7. doi: 10.4049/jimmunol.165.3.1612. J Immunol. 2000. PMID: 10903771
IL-10 is regulated at the level of transcription, but the critical motifs and the relevant transcription factors controlling this gene have remained elusive to date. ...Our results show that Stat3, by binding to a single motif in the I
IL-10 is regulated at the level of transcription, but the critical motifs and the relevant transcription factors
IL-10/STAT3/SOCS3 Axis Is Involved in the Anti-inflammatory Effect of Benznidazole.
Cevey ÁC, Penas FN, Alba Soto CD, Mirkin GA, Goren NB. Cevey ÁC, et al. Front Immunol. 2019 Jun 4;10:1267. doi: 10.3389/fimmu.2019.01267. eCollection 2019. Front Immunol. 2019. PMID: 31214200 Free PMC article.
Specific inhibition of STAT3 precluded this effect, suggesting a role for STAT3 in the increase of SOCS3 expression induced by benznidazole. ...Previously, we demonstrated that IL-10 increases the expression of SOCS3 in cult …
Specific inhibition of STAT3 precluded this effect, suggesting a role for STAT3 in the increase of SOCS3 expression
Role of endogenous IL-10 in LPS-induced STAT3 activation and IL-1 receptor antagonist gene expression.
Carl VS, Gautam JK, Comeau LD, Smith MF Jr. Carl VS, et al. J Leukoc Biol. 2004 Sep;76(3):735-42. doi: 10.1189/jlb.1003526. Epub 2004 Jun 24. J Leukoc Biol. 2004. PMID: 15218058
Western blot analysis of phosphorylated STAT3 from wild-type and IL-10-/- BMDM and IL-10 neutralization experiments demonstrated a role for endogenously produced IL-10 in the LPS-induced STAT3 activity. Togethe …
Western blot analysis of phosphorylated STAT3 from wild-type and IL-10-/- BMDM and IL-10 neutralization e …
Wogonin Suppresses IL-10 Production in B Cells via STAT3 and ERK Signaling Pathway.
Fan L, Qiu D, Huang G, Chen J, Wu Q, Xiong S, Wu C, Peng Y, Zhang Q. Fan L, et al. J Immunol Res. 2020 Jun 1;2020:3032425. doi: 10.1155/2020/3032425. eCollection 2020. J Immunol Res. 2020. PMID: 32566686 Free PMC article.
Furthermore, administration of Wogonin on LPS-treated B cells suppressed phosphorylation of STAT3 and ERK, but not AKT. Interestingly, among those IL-10 signaling-associated transcription factors, mRNA and protein levels of Hif-1alpha were specifically …
Furthermore, administration of Wogonin on LPS-treated B cells suppressed phosphorylation of STAT3 and ERK, but not AKT. Interestingly …
Lipopolysaccharide-mediated IL-10 transcriptional regulation requires sequential induction of type I IFNs and IL-27 in macrophages.
Iyer SS, Ghaffari AA, Cheng G. Iyer SS, et al. J Immunol. 2010 Dec 1;185(11):6599-607. doi: 10.4049/jimmunol.1002041. Epub 2010 Nov 1. J Immunol. 2010. PMID: 21041726 Free PMC article.
Dysregulation of IL-10 is associated with a number of autoimmune diseases, and so, understanding the mechanisms by which IL-10 gene expression is regulated remains an important area of study. ...We demonstrate that IL-27 signaling is requ …
Dysregulation of IL-10 is associated with a number of autoimmune diseases, and so, understanding the mechanisms by which IL
Grass carp (Ctenopharyngodon idella) IRAK1 and STAT3 up-regulate synergistically the transcription of IL-10.
Xie X, Xu K, Mao H, Lv Y, Weng P, Chang K, Lin G, Hu C. Xie X, et al. Fish Shellfish Immunol. 2020 Jul;102:28-35. doi: 10.1016/j.fsi.2020.04.014. Epub 2020 Apr 9. Fish Shellfish Immunol. 2020. PMID: 32278837
In vertebrates, IL-10 is an anti-inflammatory factor that serves as a key inhibitory role in a wide range of immune responses. ...Under the stimulation of LPS, IRAK1 enters the nucleus to form a dimer with STAT3 and regulates the expression
In vertebrates, IL-10 is an anti-inflammatory factor that serves as a key inhibitory role in a wide range of imm …
Regulatory Effect of JAK2/STAT3 on the Immune Function of Endotoxin-tolerant Dendritic Cells and its Involvement in Acute Liver Failure.
Chen Y, Hou C, Yang N, Yang Y, Chen Y, Kong D, Jiang Y, Lin M, Zheng S, Li S, Lu M. Chen Y, et al. J Clin Transl Hepatol. 2022 Oct 28;10(5):879-890. doi: 10.14218/JCTH.2021.00175. Epub 2022 Jan 4. J Clin Transl Hepatol. 2022. PMID: 36304491 Free PMC article.
RESULTS: Compared with control ETDCs, SOCS1(+/+)ETDCs had lower expression of costimulatory molecules, weaker allostimulatory ability, lower levels of IL-6 and TNF-alpha expression and higher IL-10 secretion. ...SOCS1(+/+)ETDCs alleviated lipopolysa
RESULTS: Compared with control ETDCs, SOCS1(+/+)ETDCs had lower expression of costimulatory molecules, weaker allostimulatory ability …
Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3K-Akt-GSK3 pathway.
Antoniv TT, Ivashkiv LB. Antoniv TT, et al. Immunology. 2011 Apr;132(4):567-77. doi: 10.1111/j.1365-2567.2010.03402.x. Epub 2011 Jan 24. Immunology. 2011. PMID: 21255011 Free PMC article.
Interleukin-10 (IL-10) is an immunosuppressive cytokine that inhibits inflammatory gene expression. ...In this study we investigated the involvement of the PI3K-Akt-GSK3 signalling pathway in IL-10-induced gene
Interleukin-10 (IL-10) is an immunosuppressive cytokine that inhibits inflammatory gene expression
The macrophage response towards LPS and its control through the p38(MAPK)-STAT3 axis.
Bode JG, Ehlting C, Häussinger D. Bode JG, et al. Cell Signal. 2012 Jun;24(6):1185-94. doi: 10.1016/j.cellsig.2012.01.018. Epub 2012 Feb 4. Cell Signal. 2012. PMID: 22330073 Review.
In macrophages detection of gram-negative bacteria particularly involves binding of the outer-wall component lipopolysaccharide (LPS) to its cognate receptor complex, comprising Toll like receptor 4 (TLR4), CD14 and MD2. ...The balanced activation of this axis is essential …
In macrophages detection of gram-negative bacteria particularly involves binding of the outer-wall component lipopolysaccharide (LPS) …
43 results