Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis.
Basavarajappa D, Wan M, Lukic A, Steinhilber D, Samuelsson B, Rådmark O.
Basavarajappa D, et al.
Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11371-6. doi: 10.1073/pnas.1410983111. Epub 2014 Jul 17.
Proc Natl Acad Sci U S A. 2014.
PMID: 25034252
Free PMC article.
5-Lipoxygenase (5LO) is a key enzyme in leukotriene (LT) biosynthesis. Two accessory proteins, coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP), can support 5LO activity. …
5-Lipoxygenase (5LO) is a key enzyme in leukotriene (LT) biosynthesis. Two accessory proteins, coactosin-like …