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Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis.
Basavarajappa D, Wan M, Lukic A, Steinhilber D, Samuelsson B, Rådmark O. Basavarajappa D, et al. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11371-6. doi: 10.1073/pnas.1410983111. Epub 2014 Jul 17. Proc Natl Acad Sci U S A. 2014. PMID: 25034252 Free PMC article.
5-Lipoxygenase (5LO) is a key enzyme in leukotriene (LT) biosynthesis. Two accessory proteins, coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP), can support 5LO activity. …
5-Lipoxygenase (5LO) is a key enzyme in leukotriene (LT) biosynthesis. Two accessory proteins, coactosin-like
The Intracellular Localisation and Phosphorylation Profile of the Human 5-Lipoxygenase Δ13 Isoform Differs from That of Its Full Length Counterpart.
Allain EP, Boudreau LH, Flamand N, Surette ME. Allain EP, et al. PLoS One. 2015 Jul 14;10(7):e0132607. doi: 10.1371/journal.pone.0132607. eCollection 2015. PLoS One. 2015. PMID: 26173130 Free PMC article.
5-Lipoxygenase (5-LO) catalyzes leukotriene (LT) biosynthesis by a mechanism that involves interactions with 5-lipoxygenase activating protein (FLAP) and coactosin-like protein (CLP). 5-LO splice variant …
5-Lipoxygenase (5-LO) catalyzes leukotriene (LT) biosynthesis by a mechanism that involves interactions with 5-lipox