Signal transduction involved in MCP-1-mediated monocytic transendothelial migration.
Blood. 2001.
PMID: 11154209
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Signal transduction involved in MCP-1-mediated monocytic transendothelial migration.
Blood. 2001 Jan 15;97(2):359-66. doi: 10.1182/blood.v97.2.359.
Blood. 2001.
PMID: 11154209
Monocyte chemoattractant protein-1 (MCP-1) is a major chemoattractant for monocytes and T lymphocytes. The MonoMac6 cell line was used to examine MCP-1 receptor-mediated signal transduction events in relation t …
Monocyte chemoattractant protein-1 (MCP-1) is a major chemoattractant for monocytes and T lymphocytes. Th …
LPS-induced MCP-1 expression in human microvascular endothelial cells is mediated by the tyrosine kinase, Pyk2 via the p38 MAPK/NF-kappaB-dependent pathway.
Mol Immunol. 2009 Feb;46(5):962-8. doi: 10.1016/j.molimm.2008.09.022. Epub 2008 Oct 26.
Mol Immunol. 2009.
PMID: 18954908
Free PMC article.
However, the mechanism involved in LPS-induced MCP-1 production in endothelial cells is not well understood. Using human microvascular endothelial cells (HMVEC), we analyzed the involvement of the non-receptor tyrosine kinase, Pyk2, in LPS-mediated …
However, the mechanism involved in LPS-induced MCP-1 production in endothelial cells is not well understood. Using huma …
Endothelial Rab7 GTPase mediates tumor growth and metastasis in lysosomal acid lipase-deficient mice.
J Biol Chem. 2017 Nov 24;292(47):19198-19208. doi: 10.1074/jbc.M116.773093. Epub 2017 Sep 18.
J Biol Chem. 2017.
PMID: 28924047
Free PMC article.
Here we report that lal(-/-) ECs facilitated in vivo tumor angiogenesis, growth, and metastasis, largely by stimulating tumor cell proliferation, migration, adhesion, and transendothelial migration via increased expression of IL-6 and monocyte chemoatt …
Here we report that lal(-/-) ECs facilitated in vivo tumor angiogenesis, growth, and metastasis, largely by stimulating tumor cell prolifera …
Overexpression of uncoupling protein 2 in THP1 monocytes inhibits beta2 integrin-mediated firm adhesion and transendothelial migration.
Arterioscler Thromb Vasc Biol. 2004 May;24(5):864-70. doi: 10.1161/01.ATV.0000125705.28058.eb. Epub 2004 Mar 11.
Arterioscler Thromb Vasc Biol. 2004.
PMID: 15016641
UCP2 overexpression reduced beta2 integrin-mediated firm adhesion of monocytes to either tumor necrosis factor-alpha (TNF-alpha)-stimulated human aortic endothelial cell (HAEC) monolayers or to plates coated with intercellular adhesion molecule-1, not vascula …
UCP2 overexpression reduced beta2 integrin-mediated firm adhesion of monocytes to either tumor necrosis factor-alpha (TNF-alph …
Monocyte chemoattractant protein-1 induces scavenger receptor expression and monocyte differentiation into foam cells.
Biochem Biophys Res Commun. 2003 May 30;305(2):380-5. doi: 10.1016/s0006-291x(03)00771-x.
Biochem Biophys Res Commun. 2003.
PMID: 12745086
Our results showed that: (1) MCP-1 increased the expression of CD36 SCR by flow cytometric analysis. (2) MCP-1 increased incorporation of 125I-labeled ox-LDL and oil red O staining. (3) MCP-1 and ox-LDL enhanced in vitro transen …
Our results showed that: (1) MCP-1 increased the expression of CD36 SCR by flow cytometric analysis. (2) MCP- …
Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation.
Cardiovasc Res. 2009 Aug 1;83(3):511-8. doi: 10.1093/cvr/cvp135. Epub 2009 Apr 30.
Cardiovasc Res. 2009.
PMID: 19406912
Free PMC article.
The differentiation of human monocytes into fibroblasts in vitro occurs after transendothelial migration (TEM) induced by monocyte chemoattractant protein 1 (MCP-1). ...We also performed in vitro assays in which human peripheral bl …
The differentiation of human monocytes into fibroblasts in vitro occurs after transendothelial migration (TEM) induced …