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Site-specific N-glycan Analysis of Antibody-binding Fc γ Receptors from Primary Human Monocytes.
Roberts JT, Patel KR, Barb AW. Roberts JT, et al. Mol Cell Proteomics. 2020 Feb;19(2):362-374. doi: 10.1074/mcp.RA119.001733. Epub 2019 Dec 30. Mol Cell Proteomics. 2020. PMID: 31888963 Free PMC article.
Furthermore, post-translational modification impacts antibody binding affinity, most notably the composition of the asparagine(N)-linked glycan at N162 of CD16a. ...The composition of CD16a N-glycans isolated from monocytes include …
Furthermore, post-translational modification impacts antibody binding affinity, most notably the composition of the asparagine …
Human immunodeficiency virus envelope (gp120) binding to DC-SIGN and primary dendritic cells is carbohydrate dependent but does not involve 2G12 or cyanovirin binding sites: implications for structural analyses of gp120-DC-SIGN binding.
Hong PW, Flummerfelt KB, de Parseval A, Gurney K, Elder JH, Lee B. Hong PW, et al. J Virol. 2002 Dec;76(24):12855-65. doi: 10.1128/jvi.76.24.12855-12865.2002. J Virol. 2002. PMID: 12438611 Free PMC article.
Endo-beta-N-glucosaminidase H (EndoH) treatment of gp120-Fc under conditions that maintained wild-type CD4 binding-and the full complement of complex glycans-significantly decreased (>90%) binding to DC-SIGN expressing cell lines, as well as …
Endo-beta-N-glucosaminidase H (EndoH) treatment of gp120-Fc under conditions that maintained wild-type CD4 binding-and …