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1994 2
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2020 0
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Sp1 is a critical factor for the monocytic specific expression of human CD14.
Zhang DE, Hetherington CJ, Tan S, Dziennis SE, Gonzalez DA, Chen HM, Tenen DG. Zhang DE, et al. J Biol Chem. 1994 Apr 15;269(15):11425-34. J Biol Chem. 1994. PMID: 7512565 Free article.
CD14 is a membrane glycoprotein expressed specifically on monocytes and macrophages, and its expression is markedly increased during the process of monocyte differentiation. ...Mutation of the major Sp1 binding site (-110 bp) decre
CD14 is a membrane glycoprotein expressed specifically on monocytes and macrophages, and its expression i
Regulation of CD14 expression during monocytic differentiation induced with 1 alpha,25-dihydroxyvitamin D3.
Zhang DE, Hetherington CJ, Gonzalez DA, Chen HM, Tenen DG. Zhang DE, et al. J Immunol. 1994 Oct 1;153(7):3276-84. J Immunol. 1994. PMID: 7522257
We have recently cloned the CD14 5' upstream sequence and demonstrated its tissue-specific promoter activity. Using stable transfection of the monocytoid U937 cell line with a series of deletion mutants of the CD14 5' upstream sequence coupled to a reporter …
We have recently cloned the CD14 5' upstream sequence and demonstrated its tissue-specific promoter activity. Using stable tra …
Lipopolysaccharide decreases single immunoglobulin interleukin-1 receptor-related molecule (SIGIRR) expression by suppressing specificity protein 1 (Sp1) via the Toll-like receptor 4 (TLR4)-p38 pathway in monocytes and neutrophils.
Ueno-Shuto K, Kato K, Tasaki Y, Sato M, Sato K, Uchida Y, Sakai H, Ono T, Suico MA, Mitsutake K, Tokutomi N, Kai H, Shuto T. Ueno-Shuto K, et al. J Biol Chem. 2014 Jun 27;289(26):18097-109. doi: 10.1074/jbc.M113.532093. Epub 2014 May 12. J Biol Chem. 2014. PMID: 24821721 Free PMC article.
Here, we found expression of SIGIRR in non-epithelial innate immune cells, including primary peripheral blood monocytes, polymorphonuclear neutrophils, monocytic RAW264 cells, and neutrophilic-differentiated HL-60 cells. ...Finally, reporter gene and c …
Here, we found expression of SIGIRR in non-epithelial innate immune cells, including primary peripheral blood monocytes, polym …
Decitabine and vitamin D3 differentially affect hematopoietic transcription factors to induce monocytic differentiation.
Koschmieder S, Agrawal S, Radomska HS, Huettner CS, Tenen DG, Ottmann OG, Berdel WE, Serve HL, Müller-Tidow C. Koschmieder S, et al. Int J Oncol. 2007 Feb;30(2):349-55. Int J Oncol. 2007. PMID: 17203216
In addition, we investigated whether the myeloid transcription factor Sp1 played a role in decitabine- and VD3-induced CD14 expression. Indeed, we found that mithramycin A, a specific inhibitor of Sp1, inhibited both VD3- and decitabine-i …
In addition, we investigated whether the myeloid transcription factor Sp1 played a role in decitabine- and VD3-induced CD14
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