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Stimulation of TNF-alpha release in monocytes by honey.
Tonks A, Cooper RA, Price AJ, Molan PC, Jones KP. Tonks A, et al. Cytokine. 2001 May 21;14(4):240-2. doi: 10.1006/cyto.2001.0868. Cytokine. 2001. PMID: 11448125
We investigated the effect of manuka, pasture and an artificial honey on macrophage function. Reactive oxygen intermediate (ROI) production was assessed by luminol enhanced chemoluminescence and tumour necrosis factor-alpha (TNF-alpha) …
We investigated the effect of manuka, pasture and an artificial honey on macrophage function. Reactive oxygen intermediate (ROI) prod …
Honey: an immunomodulator in wound healing.
Majtan J. Majtan J. Wound Repair Regen. 2014 Mar-Apr;22(2):187-92. doi: 10.1111/wrr.12117. Epub 2014 Feb 24. Wound Repair Regen. 2014. PMID: 24612472 Review.
The antibacterial activity of honey has recently been fully characterized in medical-grade honeys. ...Honey and its components are able to either stimulate or inhibit the release of certain cytokines (tumor necrosis factor- …
The antibacterial activity of honey has recently been fully characterized in medical-grade honeys. ...Honey and its com …
Honeybee apisimin and plant arabinogalactans in honey costimulate monocytes.
Gannabathula S, Krissansen GW, Skinner M, Steinhorn G, Schlothauer R. Gannabathula S, et al. Food Chem. 2015 Feb 1;168:34-40. doi: 10.1016/j.foodchem.2014.07.007. Epub 2014 Jul 9. Food Chem. 2015. PMID: 25172680
Apisimin was present in all honeys, as well as Royal Jelly. We report that apisimin shares with honey AGPs the ability to stimulate the release of TNF-alpha from blood monocytes. Further, it synergizes with AGPs to enhance the r
Apisimin was present in all honeys, as well as Royal Jelly. We report that apisimin shares with honey AGPs the ability to s
Correlation of the immunostimulatory activities of honeys with their contents of identified bioactives.
Gannabathula S, Krissansen GW, Bisson-Rowe L, Skinner M, Steinhorn G, Schlothauer R. Gannabathula S, et al. Food Chem. 2017 Apr 15;221:39-46. doi: 10.1016/j.foodchem.2016.10.038. Epub 2016 Oct 11. Food Chem. 2017. PMID: 27979219
In order to correlate bioactive content with immunostimulatory activity we compared the abilities of seventy eight New Zealand and non-New Zealand honeys to stimulate blood monocytes to release tumour necrosis factor (TNF)-alpha
In order to correlate bioactive content with immunostimulatory activity we compared the abilities of seventy eight New Zealand and non-New Z …
Honey stimulates inflammatory cytokine production from monocytes.
Tonks AJ, Cooper RA, Jones KP, Blair S, Parton J, Tonks A. Tonks AJ, et al. Cytokine. 2003 Mar 7;21(5):242-7. doi: 10.1016/s1043-4666(03)00092-9. Cytokine. 2003. PMID: 12824009
Cell culture supernatants were tested using specific ELISA assays for tumour necrosis factor-alpha (TNF-alpha) and interleukin (IL)-1beta and IL-6. All honeys significantly increased the TNF-alpha, IL-1beta and IL-6 relea
Cell culture supernatants were tested using specific ELISA assays for tumour necrosis factor-alpha (TNF-alpha
Arabinogalactan proteins contribute to the immunostimulatory properties of New Zealand honeys.
Gannabathula S, Skinner MA, Rosendale D, Greenwood JM, Mutukumira AN, Steinhorn G, Stephens J, Krissansen GW, Schlothauer RC. Gannabathula S, et al. Immunopharmacol Immunotoxicol. 2012 Aug;34(4):598-607. doi: 10.3109/08923973.2011.641974. Epub 2012 Jan 2. Immunopharmacol Immunotoxicol. 2012. PMID: 22212104
OBJECTIVE: To characterize the ability of New Zealand honeys to elicit the release of tumor necrosis factor-alpha (TNF-alpha) from monocytic cell lines as a model for early events within a wound site. ...RESULTS: All …
OBJECTIVE: To characterize the ability of New Zealand honeys to elicit the release of tumor necrosis factor