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The Role of Monocytes and Macrophages in Autoimmune Diseases: A Comprehensive Review.
Ma WT, Gao F, Gu K, Chen DK. Ma WT, et al. Front Immunol. 2019 May 24;10:1140. doi: 10.3389/fimmu.2019.01140. eCollection 2019. Front Immunol. 2019. PMID: 31178867 Free PMC article. Review.
Several lines of evidence have suggested a causal link between the presence or activation of these cells and the development of autoimmune diseases. In addition, Mo or M infiltration in diseased tissues is a hallmark of several autoimmune diseases. How …
Several lines of evidence have suggested a causal link between the presence or activation of these cells and the development of autoimmun
Role of angiopoietin-2 in inflammatory autoimmune diseases: A comprehensive review.
Wu Q, Xu WD, Huang AF. Wu Q, et al. Int Immunopharmacol. 2020 Mar;80:106223. doi: 10.1016/j.intimp.2020.106223. Epub 2020 Jan 25. Int Immunopharmacol. 2020. PMID: 31991374 Review.
Therefore, angiogenesis is closely related to pathogenesis of inflammatory autoimmune diseases. As a member of the angiopoietin family, Angiopoietin-2 (Ang-2) plays an irreplaceable role in angiogenesis. This review will narrate the expression of Ang-2 …
Therefore, angiogenesis is closely related to pathogenesis of inflammatory autoimmune diseases. As a member of the angiopoieti …
Role of TL1A in Inflammatory Autoimmune Diseases: A Comprehensive Review.
Xu WD, Li R, Huang AF. Xu WD, et al. Front Immunol. 2022 Jul 14;13:891328. doi: 10.3389/fimmu.2022.891328. eCollection 2022. Front Immunol. 2022. PMID: 35911746 Free PMC article. Review.
TL1A, also called TNFSF15, is a member of tumor necrosis factor family. It is expressed in different immune cell, such as monocyte, macrophage, dendritic cell, T cell and non-immune cell, for example, synovial fibroblast, endothelial cell. ...In vivo and in vitro st …
TL1A, also called TNFSF15, is a member of tumor necrosis factor family. It is expressed in different immune cell, such as monocyte, …
Current Understanding of the Immunomodulatory Activities of High-Density Lipoproteins.
Trakaki A, Marsche G. Trakaki A, et al. Biomedicines. 2021 May 21;9(6):587. doi: 10.3390/biomedicines9060587. Biomedicines. 2021. PMID: 34064071 Free PMC article. Review.
HDL suppresses immune cell activation at least in part by modulating the cholesterol content in cholesterol/sphingolipid-rich membrane domains (lipid rafts), which play a critical role in the compartmentalization of signaling pathways. Acute infections, inflammation or …
HDL suppresses immune cell activation at least in part by modulating the cholesterol content in cholesterol/sphingolipid-rich membrane domai …
Toll-like receptors in older adults.
van Duin D, Shaw AC. van Duin D, et al. J Am Geriatr Soc. 2007 Sep;55(9):1438-44. doi: 10.1111/j.1532-5415.2007.01300.x. J Am Geriatr Soc. 2007. PMID: 17767688 Review.
Toll-like receptors (TLRs) recognize a limited number of conserved elements in pathogens and, by activating antigen-presenting cells such as dendritic cells and monocytes and macrophages, play a crucial role in the immune response to infection and vaccination …
Toll-like receptors (TLRs) recognize a limited number of conserved elements in pathogens and, by activating antigen-presenting cells such as …
Innate immunity, epigenetics and autoimmunity in rheumatoid arthritis.
Maciejewska Rodrigues H, Jüngel A, Gay RE, Gay S. Maciejewska Rodrigues H, et al. Mol Immunol. 2009 Nov;47(1):12-8. doi: 10.1016/j.molimm.2009.01.010. Epub 2009 Feb 15. Mol Immunol. 2009. PMID: 19232437
RA remains an incurable condition, although a new class of drugs, biologicals, have made a major breakthrough in targeting and/or eliminating the immune cells, including T cells, B cells and monocytes/macrophages from the joints. That we cannot (yet?) cure the disea …
RA remains an incurable condition, although a new class of drugs, biologicals, have made a major breakthrough in targeting and/or eliminatin …