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The antiinflammatory drug sulfasalazine inhibits tumor necrosis factor alpha expression in macrophages by inducing apoptosis.
Rodenburg RJ, Ganga A, van Lent PL, van de Putte LB, van Venrooij WJ. Rodenburg RJ, et al. Arthritis Rheum. 2000 Sep;43(9):1941-50. doi: 10.1002/1529-0131(200009)43:9<1941::AID-ANR4>3.0.CO;2-O. Arthritis Rheum. 2000. PMID: 11014343 Free article.
OBJECTIVE: Sulfasalazine (SSZ) is a commonly used drug in the treatment of inflammatory diseases such as rheumatoid arthritis and Crohn's disease. In both diseases, the proinflammatory cytokine tumor necrosis factor alpha (T …
OBJECTIVE: Sulfasalazine (SSZ) is a commonly used drug in the treatment of inflammatory diseases such as rheumatoid art …
Marine hydroquinone zonarol prevents inflammation and apoptosis in dextran sulfate sodium-induced mice ulcerative colitis.
Yamada S, Koyama T, Noguchi H, Ueda Y, Kitsuyama R, Shimizu H, Tanimoto A, Wang KY, Nawata A, Nakayama T, Sasaguri Y, Satoh T. Yamada S, et al. PLoS One. 2014 Nov 19;9(11):e113509. doi: 10.1371/journal.pone.0113509. eCollection 2014. PLoS One. 2014. PMID: 25409433 Free PMC article.
Zonarol treatment significantly reduced the expression of pro-inflammatory signaling molecules, and prevented the apoptosis of intestinal epithelial cells. Finally, zonarol protected against in vitro lipopolysaccharide (LPS)-induced activation in the R …
Zonarol treatment significantly reduced the expression of pro-inflammatory signaling molecules, and prevented the apoptosis
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