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The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2.
Rodríguez-Frade JM, Vila-Coro AJ, de Ana AM, Albar JP, Martínez-A C, Mellado M. Rodríguez-Frade JM, et al. Proc Natl Acad Sci U S A. 1999 Mar 30;96(7):3628-33. doi: 10.1073/pnas.96.7.3628. Proc Natl Acad Sci U S A. 1999. PMID: 10097088 Free PMC article.
Cytokines interact with hematopoietin superfamily receptors and stimulate receptor dimerization. We demonstrate that chemoattractant cytokines (chemokines) also trigger biological responses through receptor dimerization. Functio …
Cytokines interact with hematopoietin superfamily receptors and stimulate receptor dimerization. We demonstrate that ch …
Tyrosine phosphorylation-mediated signal transduction in MCP-1-induced macrophage activation: role for receptor dimerization, focal adhesion protein complex and JAK/STAT pathway.
Biswas SK, Sodhi A. Biswas SK, et al. Int Immunopharmacol. 2002 Jul;2(8):1095-107. doi: 10.1016/s1567-5769(02)00055-3. Int Immunopharmacol. 2002. PMID: 12349947
Monocyte chemoattractant protein-1 (MCP-1) plays a crucial role in the recruitment of monocytes/macrophages associated with several inflammatory diseases and malignancies. ...Present investigations suggest that the early events in the tyrosine kinase s …
Monocyte chemoattractant protein-1 (MCP-1) plays a crucial role in the recruitment of monocytes/macrophages asso …
Bioluminescence resonance energy transfer reveals ligand-induced conformational changes in CXCR4 homo- and heterodimers.
Percherancier Y, Berchiche YA, Slight I, Volkmer-Engert R, Tamamura H, Fujii N, Bouvier M, Heveker N. Percherancier Y, et al. J Biol Chem. 2005 Mar 18;280(11):9895-903. doi: 10.1074/jbc.M411151200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632118 Free article.
Homo- and heterodimerization have emerged as prominent features of G-protein-coupled receptors with possible impact on the regulation of their activity. Using a sensitive bioluminescence resonance energy transfer system, we investigated the formation of CXCR4 and CCR2 …
Homo- and heterodimerization have emerged as prominent features of G-protein-coupled receptors with possible impact on the regulation …