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The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF.
Belge KU, Dayyani F, Horelt A, Siedlar M, Frankenberger M, Frankenberger B, Espevik T, Ziegler-Heitbrock L. Belge KU, et al. J Immunol. 2002 Apr 1;168(7):3536-42. doi: 10.4049/jimmunol.168.7.3536. J Immunol. 2002. PMID: 11907116 Free article.
In human blood two monocyte populations can be distinguished, i.e., the CD14(++)CD16(-)DR(+) classical monocytes and the CD14(+)CD16(+)DR(++) proinflammatory monocytes that account for only 10% of all monocy
In human blood two monocyte populations can be distinguished, i.e., the CD14(++)CD16(-)DR(+) classical monocy
Differential TNF production by monocyte subsets under physical stress: blunted mobilization of proinflammatory monocytes in prehypertensive individuals.
Dimitrov S, Shaikh F, Pruitt C, Green M, Wilson K, Beg N, Hong S. Dimitrov S, et al. Brain Behav Immun. 2013 Jan;27(1):101-8. doi: 10.1016/j.bbi.2012.10.003. Epub 2012 Oct 6. Brain Behav Immun. 2013. PMID: 23046723 Free PMC article.
We compared nonclassical (CD14(+)CD16(++); HLA-DR(+)), intermediate (CD14(++)CD16(+); HLA-DR(++)), and classical (CD14(++)CD16(-); HLA-DR(+/-)) monocyte trafficking and their LPS-stimulated TNF productio …
We compared nonclassical (CD14(+)CD16(++); HLA-DR(+)), intermediate (CD14(++)CD16(+); HLA-DR(++)), …
Elevated CD16 expression by monocytes from patients with tumor necrosis factor receptor-associated periodic syndrome.
Todd I, Radford PM, Ziegler-Heitbrock L, Ghaemmaghami AM, Powell RJ, Tighe PJ. Todd I, et al. Arthritis Rheum. 2007 Dec;56(12):4182-8. doi: 10.1002/art.23133. Arthritis Rheum. 2007. PMID: 18050249 Free article.
OBJECTIVE: Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is an inherited autosomal-dominant autoinflammatory condition caused by mutations in the ectodomain of the 55-kd tumor necrosis factor (TNF) receptor superfamily 1A. Proinflammatory blood …
OBJECTIVE: Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is an inherited autosomal-dominant autoinflammatory condition …
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