The role of zinc in calprotectin expression in human myeloid cells.
J Trace Elem Med Biol. 2018.
PMID: 29895358
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The role of zinc in calprotectin expression in human myeloid cells.
J Trace Elem Med Biol. 2018 Sep;49:106-112. doi: 10.1016/j.jtemb.2018.04.022. Epub 2018 Apr 23.
J Trace Elem Med Biol. 2018.
PMID: 29895358
We could depict that zinc deficiency alone enhances mRNA and protein expression of calprotectin in myeloid cells, independently from maturity stage. ...Our findings suggest that zinc does not only regulate the activity of calprotectin …
We could depict that zinc deficiency alone enhances mRNA and protein expression of calprotectin in myeloid ce …
The role of calprotectin in pediatric disease.
Biomed Res Int. 2013;2013:542363. doi: 10.1155/2013/542363. Epub 2013 Sep 23.
Biomed Res Int. 2013.
PMID: 24175291
Free PMC article.
Review.
Calprotectin (CP) is a calcium- and zinc-binding protein of the S100 family expressed mainly by neutrophils with important extracellular activity. ...Further studies are required to provide insights into the actual role of CP in these pathological proc …
Calprotectin (CP) is a calcium- and zinc-binding protein of the S100 family expressed mainly by neutrophils with import …
New Insights into the Role of Zinc Acquisition and Zinc Tolerance in Group A Streptococcal Infection.
Infect Immun. 2018 May 22;86(6):e00048-18. doi: 10.1128/IAI.00048-18. Print 2018 Jun.
Infect Immun. 2018.
PMID: 29581188
Free PMC article.
Zinc plays an important role in host innate immune function. However, the innate immune system also utilizes zinc starvation ("nutritional immunity") to combat infections. Here, we investigate the role of zinc import and export in the protection …
Zinc plays an important role in host innate immune function. However, the innate immune system also utilizes zinc starv …
Manganese and microbial pathogenesis: sequestration by the Mammalian immune system and utilization by microorganisms.
ACS Chem Biol. 2015 Mar 20;10(3):641-51. doi: 10.1021/cb500792b. Epub 2015 Jan 16.
ACS Chem Biol. 2015.
PMID: 25594606
Free PMC article.
Review.
Bacterial and fungal pathogens cause a variety of infectious diseases and constitute a significant threat to public health. The human innate immune system represents the first line of defense against pathogenic microbes and employs a range of chemical artillery to combat t …
Bacterial and fungal pathogens cause a variety of infectious diseases and constitute a significant threat to public health. The human …
Zinc piracy as a mechanism of Neisseria meningitidis for evasion of nutritional immunity.
PLoS Pathog. 2013 Oct;9(10):e1003733. doi: 10.1371/journal.ppat.1003733. Epub 2013 Oct 31.
PLoS Pathog. 2013.
PMID: 24204275
Free PMC article.
Expression of CbpA enables N. meningitidis to survive and propagate in the presence of calprotectin and to use calprotectin as a zinc source. ...Together, our results demonstrate that N. meningitidis is able to subvert an important defense mechanism of …
Expression of CbpA enables N. meningitidis to survive and propagate in the presence of calprotectin and to use calprotectin …
Neutrophil-Associated Responses to Vibrio cholerae Infection in a Natural Host Model.
Infect Immun. 2022 Mar 17;90(3):e0046621. doi: 10.1128/iai.00466-21. Epub 2022 Jan 24.
Infect Immun. 2022.
PMID: 35072520
Free PMC article.
The expression of downstream calprotectin targets was also significantly increased in the zebrafish. ...This study also establishes a major role for calprotectin in combating infectious diseases in zebrafish....
The expression of downstream calprotectin targets was also significantly increased in the zebrafish. ...This study also establ …
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