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Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay.
Ochs MJ, Sorg BL, Pufahl L, Grez M, Suess B, Steinhilber D. Ochs MJ, et al. PLoS One. 2012;7(2):e31363. doi: 10.1371/journal.pone.0031363. Epub 2012 Feb 21. PLoS One. 2012. PMID: 22363630 Free PMC article.
The characterization of one of the splice variants, 5-LOdelta3, revealed that it is a target for NMD since knockdown of the NMD factors UPF1, UPF2 and UPF3b in the human monocytic cell line Mono Mac 6 (MM6) altered the ex …
The characterization of one of the splice variants, 5-LOdelta3, revealed that it is a target for NMD since knockdown of the NMD facto …