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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 5
2003 2
2004 1
2005 4
2006 2
2007 3
2008 4
2009 3
2012 3
2013 1
2014 4
2015 5
2016 2
2017 1
2018 2
2019 2
2020 1
2022 1
2024 1

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42 results

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Page 1
Transcriptional regulation of the human toll-like receptor 2 gene in monocytes and macrophages.
Haehnel V, Schwarzfischer L, Fenton MJ, Rehli M. Haehnel V, et al. J Immunol. 2002 Jun 1;168(11):5629-37. doi: 10.4049/jimmunol.168.11.5629. J Immunol. 2002. PMID: 12023360
This report investigates the molecular basis for tissue-restricted and regulated expression of the pattern recognition receptor Toll-like receptor (TLR)2 in human monocytes and macrophages. ...Our findings provide an initial definition of the human
This report investigates the molecular basis for tissue-restricted and regulated expression of the pattern recognition receptor Toll- …
Gene Silencing of Toll-like Receptor 2 Gene Expression as a Tactic to Control Mycobacterium Tuberculosis and Granuloma Formation.
Nama MA. Nama MA. Arch Razi Inst. 2022 Apr 30;77(2):827-834. doi: 10.22092/ARI.2022.357152.1984. eCollection 2022 Apr. Arch Razi Inst. 2022. PMID: 36284966 Free PMC article.
Due to the increasing frequency of antimicrobial treatment resistance and problems in vaccine development, the pathogenesis of TB for its survival and growth is highly dependent on host lipids and stimulated-lipid droplets formation. Toll-like receptor 2
Due to the increasing frequency of antimicrobial treatment resistance and problems in vaccine development, the pathogenesis of TB for its su …
Regulation and biological role of the peptide/histidine transporter SLC15A3 in Toll-like receptor-mediated inflammatory responses in macrophage.
Song F, Yi Y, Li C, Hu Y, Wang J, Smith DE, Jiang H. Song F, et al. Cell Death Dis. 2018 Jul 10;9(7):770. doi: 10.1038/s41419-018-0809-1. Cell Death Dis. 2018. PMID: 29991810 Free PMC article.
In this study, mouse peritoneal macrophages (PMs), mouse bone marrow-derived macrophages (BMDMs), the human acute monocytic leukemia cell line THP-1 and the human lung epithelial carcinoma cell line A549 were used to investigate the regulatio
In this study, mouse peritoneal macrophages (PMs), mouse bone marrow-derived macrophages (BMDMs), the human acute mo
Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response.
Bösl K, Giambelluca M, Haug M, Bugge M, Espevik T, Kandasamy RK, Bergstrøm B. Bösl K, et al. Front Physiol. 2018 May 29;9:618. doi: 10.3389/fphys.2018.00618. eCollection 2018. Front Physiol. 2018. PMID: 29896111 Free PMC article.
We investigated a phenomenon where co-signaling from TLR2 and TLR8 in human primary monocytes provides a distinct immune activation profile compared to signaling from either TLR alone. We compare gene signatures induced by either stimulus alone or together an …
We investigated a phenomenon where co-signaling from TLR2 and TLR8 in human primary monocytes provides a distinct immune activ …
Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by miR-132 and miR-212.
Nahid MA, Yao B, Dominguez-Gutierrez PR, Kesavalu L, Satoh M, Chan EK. Nahid MA, et al. J Immunol. 2013 Feb 1;190(3):1250-63. doi: 10.4049/jimmunol.1103060. Epub 2012 Dec 21. J Immunol. 2013. PMID: 23264652 Free PMC article.
TLR signaling-mediated cytokine production must be properly regulated to prevent pathological conditions deriving from overproduction of cytokines. In this study, the role of specific microRNAs in TLR-signaling pathway was investigated to reveal the cross-interaction and - …
TLR signaling-mediated cytokine production must be properly regulated to prevent pathological conditions deriving from overproduction …
Francisella tularensis LPS induces the production of cytokines in human monocytes and signals via Toll-like receptor 4 with much lower potency than E. coli LPS.
Dueñas AI, Aceves M, Orduña A, Díaz R, Sánchez Crespo M, García-Rodríguez C. Dueñas AI, et al. Int Immunol. 2006 May;18(5):785-95. doi: 10.1093/intimm/dxl015. Epub 2006 Mar 30. Int Immunol. 2006. PMID: 16574669
Conversely, TLR2, TLR2/TLR1 or TLR2/TLR6 transfected cells did not show kappaB-driven transcriptional activity in the presence of F. tularensis LPS. In human monocytic cells, F. tularensis LPS activated extracellular signal-regulated kinases and the pr …
Conversely, TLR2, TLR2/TLR1 or TLR2/TLR6 transfected cells did not show kappaB-driven transcriptional activity in the presence of F. …
Aldosterone induces trained immunity: the role of fatty acid synthesis.
van der Heijden CDCC, Keating ST, Groh L, Joosten LAB, Netea MG, Riksen NP. van der Heijden CDCC, et al. Cardiovasc Res. 2020 Feb 1;116(2):317-328. doi: 10.1093/cvr/cvz137. Cardiovasc Res. 2020. PMID: 31119285
AIMS: Supranormal levels of aldosterone are associated with an increased cardiovascular risk in humans, and with accelerated atherosclerosis in animal models. Atherosclerosis is a low-grade inflammatory disorder, with monocyte-derived macrophages as major dri …
AIMS: Supranormal levels of aldosterone are associated with an increased cardiovascular risk in humans, and with accelerated atherosc …
Tetradecanoyl phorbol acetate induces expression of Toll-like receptor 2 in U937 cells: involvement of PKC, ERK, and NF-kappaB.
Jang BC, Jung TY, Paik JH, Kwon YK, Shin SW, Kim SP, Ha JS, Suh MH, Suh SI. Jang BC, et al. Biochem Biophys Res Commun. 2005 Mar 4;328(1):70-7. doi: 10.1016/j.bbrc.2004.12.144. Biochem Biophys Res Commun. 2005. PMID: 15670752
Though induction of TLR2 or TLR4 by 12-O-tetradecanoyl phorbol 13-acetate (TPA) in leukemia cells has been reported, however, the mechanism by which TPA up-regulates TLR2 or TLR4 remains poorly understood. In this study, we investigated the effect of TPA on induction of TL …
Though induction of TLR2 or TLR4 by 12-O-tetradecanoyl phorbol 13-acetate (TPA) in leukemia cells has been reported, however, the mechanism …
Expression of M-Ficolin in human monocytes and macrophages.
Frankenberger M, Schwaeble W, Ziegler-Heitbrock L. Frankenberger M, et al. Mol Immunol. 2008 Mar;45(5):1424-30. doi: 10.1016/j.molimm.2007.08.014. Epub 2007 Oct 10. Mol Immunol. 2008. PMID: 17928056
Monocyte-derived macrophages generated by in vitro culture for 5 days strongly reduced M-Ficolin mRNA and protein. Mature tissue macrophages from the lung and from breast milk also showed a very low level of M-Ficolin transcripts. ...
Monocyte-derived macrophages generated by in vitro culture for 5 days strongly reduced M-Ficolin mRNA and protein. Mature tiss
Vibrio cholerae porin OmpU mediates M1-polarization of macrophages/monocytes via TLR1/TLR2 activation.
Khan J, Sharma PK, Mukhopadhaya A. Khan J, et al. Immunobiology. 2015 Nov;220(11):1199-209. doi: 10.1016/j.imbio.2015.06.009. Epub 2015 Jun 5. Immunobiology. 2015. PMID: 26093918
PAMP-mediated monocyte/macrophage polarization is important during the infection, as pathogen can suppress host immune system by altering the polarization status of the macrophages/monocytes. OmpU, an outer membrane porin protein of Vibrio cholerae, po …
PAMP-mediated monocyte/macrophage polarization is important during the infection, as pathogen can suppress host immune system …
42 results