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Variable major lipoprotein is a principal TNF-inducing factor of louse-borne relapsing fever.
Vidal V, Scragg IG, Cutler SJ, Rockett KA, Fekade D, Warrell DA, Wright DJ, Kwiatkowski D. Vidal V, et al. Nat Med. 1998 Dec;4(12):1416-20. doi: 10.1038/4007. Nat Med. 1998. PMID: 9846580
We have undertaken the quantitative purification of the components of B. recurrentis that stimulate human monocytes to produce tumor necrosis factor. We show that the predominant factor inducing tumor necrosis factor is a variable lipoprotein
We have undertaken the quantitative purification of the components of B. recurrentis that stimulate human monocytes to produce tumor necrosi …
Structural characterization of the inflammatory moiety of a variable major lipoprotein of Borrelia recurrentis.
Scragg IG, Kwiatkowski D, Vidal V, Reason A, Paxton T, Panico M, Dell A, Morris H. Scragg IG, et al. J Biol Chem. 2000 Jan 14;275(2):937-41. doi: 10.1074/jbc.275.2.937. J Biol Chem. 2000. PMID: 10625630 Free article.
Louse-borne relapsing fever, caused by Borrelia recurrentis, provides one of the best documented examples of the causative role of tumor necrosis factor (TNF) in the pathology of severe infection in humans. We have identified the princ
Louse-borne relapsing fever, caused by Borrelia recurrentis, provides one of the best documented examples of the