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What Are the Peripheral Blood Determinants for Increased Osteoclast Formation in the Various Inflammatory Diseases Associated With Bone Loss?
de Vries TJ, El Bakkali I, Kamradt T, Schett G, Jansen IDC, D'Amelio P. de Vries TJ, et al. Front Immunol. 2019 Mar 19;10:505. doi: 10.3389/fimmu.2019.00505. eCollection 2019. Front Immunol. 2019. PMID: 30941138 Free PMC article. Review.
In this review, we used a systematic approach to review the literature on osteoclast formation in peripheral blood in patients with inflammatory diseases associated with bone loss. ...Future research will likely uncov …
In this review, we used a systematic approach to review the literature on osteoclast formation in peripheral blood
Tristetraprolin Is Required for Alveolar Bone Homeostasis.
Steinkamp HM, Hathaway-Schrader JD, Chavez MB, Aartun JD, Zhang L, Jensen T, Shojaee Bakhtiari A, Helke KL, Stumpo DJ, Alekseyenko AV, Novince CM, Blackshear PJ, Kirkwood KL. Steinkamp HM, et al. J Dent Res. 2018 Jul;97(8):946-953. doi: 10.1177/0022034518756889. Epub 2018 Mar 7. J Dent Res. 2018. PMID: 29514008 Free PMC article.
Bone loss was associated with significant increases in inflammatory cell infiltration and an increased percentage of alveolar bone surfaces apposed with TRAP+ cells. ...Finally, the oral microbiome in the TTP KO mice was significan
Bone loss was associated with significant increases in inflammatory cell infiltration and an increased
Increased chemotaxis and activity of circulatory myeloid progenitor cells may contribute to enhanced osteoclastogenesis and bone loss in the C57BL/6 mouse model of collagen-induced arthritis.
Ikić Matijašević M, Flegar D, Kovačić N, Katavić V, Kelava T, Šućur A, Ivčević S, Cvija H, Lazić Mosler E, Kalajzić I, Marušić A, Grčević D. Ikić Matijašević M, et al. Clin Exp Immunol. 2016 Dec;186(3):321-335. doi: 10.1111/cei.12862. Epub 2016 Oct 18. Clin Exp Immunol. 2016. PMID: 27612450 Free PMC article.
Our study aimed to determine the functional activity of different osteoclast progenitor (OCP) subpopulations and signals important for their migration to bone lesions, causing local and systemic bone resorption during the course of collagen-induced art …
Our study aimed to determine the functional activity of different osteoclast progenitor (OCP) subpopulations and signals impor …
Periarticular bone loss in antigen-induced arthritis.
Engdahl C, Lindholm C, Stubelius A, Ohlsson C, Carlsten H, Lagerquist MK. Engdahl C, et al. Arthritis Rheum. 2013 Nov;65(11):2857-65. doi: 10.1002/art.38114. Arthritis Rheum. 2013. PMID: 23918694 Free PMC article.
OBJECTIVE: Bone loss in arthritis is a complex process characterized by bone erosions and periarticular and generalized bone loss. ...CONCLUSION: The initiation of AIA resulted in periarticular bone loss associated with loca …
OBJECTIVE: Bone loss in arthritis is a complex process characterized by bone erosions and periarticular and generalized …
Expression of RANKL by peripheral neutrophils and its association with bone mineral density in COPD.
Hu X, Sun Y, Xu W, Lin T, Zeng H. Hu X, et al. Respirology. 2017 Jan;22(1):126-132. doi: 10.1111/resp.12878. Epub 2016 Aug 23. Respirology. 2017. PMID: 27552066
BACKGROUND AND OBJECTIVE: Osteoporosis is a major co-morbidity of COPD, but the mechanistic links between diseases of the lung and the bone remain elusive. Human neutrophils express the osteoclast activation factor RANKL (receptor activator of NF-kB ligand) a …
BACKGROUND AND OBJECTIVE: Osteoporosis is a major co-morbidity of COPD, but the mechanistic links between diseases of the lung and th …
Bone density and hyperlipidemia: the T-lymphocyte connection.
Graham LS, Tintut Y, Parhami F, Kitchen CM, Ivanov Y, Tetradis S, Effros RB. Graham LS, et al. J Bone Miner Res. 2010 Nov;25(11):2460-9. doi: 10.1002/jbmr.148. J Bone Miner Res. 2010. PMID: 20533376 Free PMC article.
Our previous studies have shown that mice fed an atherogenic high-fat diet developed osteopenia and that bone marrow preosteoclasts from these hyperlipidemic mice have increased osteoclastic potential. ...Coculture studies showed that bone marrow cells …
Our previous studies have shown that mice fed an atherogenic high-fat diet developed osteopenia and that bone marrow preosteoclasts f …
Diverse effects of Porphyromonas gingivalis on human osteoclast formation.
Scheres N, de Vries TJ, Brunner J, Crielaard W, Laine ML, Everts V. Scheres N, et al. Microb Pathog. 2011 Sep;51(3):149-55. doi: 10.1016/j.micpath.2011.04.006. Epub 2011 Apr 27. Microb Pathog. 2011. PMID: 21539907
Porphyromonas gingivalis is associated with periodontitis, a chronic inflammatory disease of the tooth-supporting tissues. A major clinical symptom is alveolar bone loss due to excessive resorption by osteoclasts. P. gingivalis may influe …
Porphyromonas gingivalis is associated with periodontitis, a chronic inflammatory disease of the tooth-supporting tissu …
Pre-B cell colony enhancing factor/NAMPT/visfatin and its role in inflammation-related bone disease.
Moschen AR, Geiger S, Gerner R, Tilg H. Moschen AR, et al. Mutat Res. 2010 Aug 7;690(1-2):95-101. doi: 10.1016/j.mrfmmm.2009.06.012. Epub 2009 Jul 5. Mutat Res. 2010. PMID: 19583971
Chronic inflammation affects bone metabolism and is commonly associated with the presence of osteoporosis. ...We studied serum levels of PBEF/NAMPT/visfatin in patients with inflammatory bowel diseases (IBD) and their relation with bone m …
Chronic inflammation affects bone metabolism and is commonly associated with the presence of osteoporosis. ...We studie …