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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 2
1993 7
1994 19
1995 19
1996 44
1997 31
1998 64
1999 57
2000 58
2001 65
2002 77
2003 67
2004 84
2005 67
2006 81
2007 84
2008 94
2009 84
2010 90
2011 99
2012 112
2013 93
2014 94
2015 102
2016 106
2017 97
2018 69
2019 76
2020 40
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Suppression of antigen presentation by IL-10.
Mittal SK, Roche PA. Mittal SK, et al. Curr Opin Immunol. 2015 Jun;34:22-7. doi: 10.1016/j.coi.2014.12.009. Epub 2015 Jan 16. Curr Opin Immunol. 2015. PMID: 25597442 Free PMC article. Review.
IL-10 is an immunosuppressive cytokine that regulates immune responses by inhibiting the ability of APCs to present antigens to T cells in a variety of ways. The mechanisms of IL-10-mediated immunosuppression include interference i …
IL-10 is an immunosuppressive cytokine that regulates immune responses by inhibiting the ability of APCs to present …
Cellular targets of regulatory B cell-mediated suppression.
Rosser EC, Blair PA, Mauri C. Rosser EC, et al. Mol Immunol. 2014 Dec;62(2):296-304. doi: 10.1016/j.molimm.2014.01.014. Epub 2014 Feb 18. Mol Immunol. 2014. PMID: 24556109 Review.
Regulatory B cells (Bregs) are defined by their ability to restrain inflammatory responses both in vivo and in vitro. Interleukin 10 (IL-10) production by Bregs is thought to be central to their ability to regulate inflammation, largely due to IL-10s' ability …
Regulatory B cells (Bregs) are defined by their ability to restrain inflammatory responses both in vivo and in vitro. Interleukin
Revival of CD8+ Treg-mediated suppression.
Smith TR, Kumar V. Smith TR, et al. Trends Immunol. 2008 Jul;29(7):337-42. doi: 10.1016/j.it.2008.04.002. Epub 2008 May 29. Trends Immunol. 2008. PMID: 18514574 Review.
We also focus on a newly described subset, CD8alphaalpha(+)TCRalphabeta(+) Tregs, which in mice recognize a T-cell receptor-derived peptide in the context of the class Ib major histocompatibility complex molecule Qa-1. ...
We also focus on a newly described subset, CD8alphaalpha(+)TCRalphabeta(+) Tregs, which in mice recognize a T-cell receptor-derived p …
Immune tolerance: are regulatory T cell subsets needed to explain suppression of autoimmunity?
Tian L, Humblet-Baron S, Liston A. Tian L, et al. Bioessays. 2012 Jul;34(7):569-75. doi: 10.1002/bies.201100180. Epub 2012 Mar 15. Bioessays. 2012. PMID: 22419393 Review.
The potential for self-reactive T cells to cause autoimmune disease is held in check by Foxp3(+) regulatory T cells (Tregs), essential mediators of peripheral immunological tolerance. Tregs have the capacity to suppress multiple branches of the immune system, …
The potential for self-reactive T cells to cause autoimmune disease is held in check by Foxp3(+) regulatory T cells (Tregs), essential me
Importance of IL-10 for CTLA-4-mediated inhibition of tumor-eradicating immunity.
Jovasevic VM, Gorelik L, Bluestone JA, Mokyr MB. Jovasevic VM, et al. J Immunol. 2004 Feb 1;172(3):1449-54. doi: 10.4049/jimmunol.172.3.1449. J Immunol. 2004. PMID: 14734721 Free article.
In this study, we show that engagement of CTLA-4 on tumor-infiltrating lymphocytes from low-dose melphalan (L-phenylalanine mustard (L-PAM))-treated MOPC-315 tumor bearers led to IL-10 secretion. In addition, the inhibitory activity of CTLA-4 ligation for IFN-gamma secreti …
In this study, we show that engagement of CTLA-4 on tumor-infiltrating lymphocytes from low-dose melphalan (L-phenylalanine mustard (L-PAM)) …
Interleukin-10-secreting Peyer's patch cells are responsible for active suppression in low-dose oral tolerance.
Tsuji NM, Mizumachi K, Kurisaki J. Tsuji NM, et al. Immunology. 2001 Aug;103(4):458-64. doi: 10.1046/j.1365-2567.2001.01265.x. Immunology. 2001. PMID: 11529936 Free PMC article.
We demonstrate the induction of antigen-specific interleukin-10 (IL-10)-secreting cells in murine Peyer's patches (PPs) after low-dose beta-lactoglobulin (BLG) feeding. ...On either side of this range, T-helper 1-like cytokine responses w …
We demonstrate the induction of antigen-specific interleukin-10 (IL-10)-secreting cells in murine Peyer's
Induction of immunological tolerance to adenoviral vectors by using a novel dendritic cell-based strategy.
Kushwah R, Oliver JR, Duan R, Zhang L, Keshavjee S, Hu J. Kushwah R, et al. J Virol. 2012 Apr;86(7):3422-35. doi: 10.1128/JVI.06172-11. Epub 2012 Jan 18. J Virol. 2012. PMID: 22258241 Free PMC article.
The success of helper-dependent adenoviral (HD-Ad) vector-mediated lung gene therapy is hampered by the host immune response, which limits pulmonary transgene expression following multiple rounds of vector readminstration. ...Taken together, these studies ide …
The success of helper-dependent adenoviral (HD-Ad) vector-mediated lung gene therapy is hampered by the host immune res …
Urocanic acid and cutaneous antigen presentation.
Lappin MB, Simon JC. Lappin MB, et al. J Photochem Photobiol B. 1998 Jul 10;44(2):112-6. doi: 10.1016/S1011-1344(98)00129-8. J Photochem Photobiol B. 1998. PMID: 9757592 Review.
Exposure to UVB results in the isomerization of trans-urocanic acid (UCA), localized in the stratum corneum, to cis-UCA. Cis-UCA can mediate at least some of the immunosuppressive effects of UVB, though the mechanism of cis-UCA action remains incompletely defined. H …
Exposure to UVB results in the isomerization of trans-urocanic acid (UCA), localized in the stratum corneum, to cis-UCA. Cis-UCA can medi
Induction of low dose oral tolerance in IL-10 deficient mice with experimental autoimmune encephalomyelitis.
Gonnella PA, Waldner HP, Kodali D, Weiner HL. Gonnella PA, et al. J Autoimmun. 2004 Nov;23(3):193-200. doi: 10.1016/j.jaut.2004.08.001. J Autoimmun. 2004. PMID: 15501390
IL-10 has been shown to be an important anti-inflammatory mediator that has both down-regulatory and immunomodulatory effects. ...These results demonstrate that IL-10 is not required for the induction of low dose oral tolerance but is required for the …
IL-10 has been shown to be an important anti-inflammatory mediator that has both down-regulatory and immunomodulatory effects. …
Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis.
Izcue A, Hue S, Buonocore S, Arancibia-Cárcamo CV, Ahern PP, Iwakura Y, Maloy KJ, Powrie F. Izcue A, et al. Immunity. 2008 Apr;28(4):559-70. doi: 10.1016/j.immuni.2008.02.019. Immunity. 2008. PMID: 18400195 Free PMC article.
Interleukin-23 (IL-23) is an inflammatory cytokine that plays a key role in the pathogenesis of several autoimmune and inflammatory diseases. It orchestrates innate and T cell-mediated inflammatory pathways and can promote T helper 17 (Th17) cell responses. ...
Interleukin-23 (IL-23) is an inflammatory cytokine that plays a key role in the pathogenesis of several autoimmune and inflammatory d
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