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Year Number of Results
1992 2
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2007 84
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2,060 results

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Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression.
Sing A, Rost D, Tvardovskaia N, Roggenkamp A, Wiedemann A, Kirschning CJ, Aepfelbacher M, Heesemann J. Sing A, et al. J Exp Med. 2002 Oct 21;196(8):1017-24. doi: 10.1084/jem.20020908. J Exp Med. 2002. PMID: 12391013 Free PMC article.
A characteristic of the three human-pathogenic Yersinia spp. (the plague agent Yersinia pestis and the enteropathogenic Yersinia pseudotuberculosis and Yersinia enterocolitica) is the expression of the virulence (V)-antigen (LcrV). LcrV i …
A characteristic of the three human-pathogenic Yersinia spp. (the plague agent Yersinia pestis and the enteropathogenic Yer …
Revival of CD8+ Treg-mediated suppression.
Smith TR, Kumar V. Smith TR, et al. Trends Immunol. 2008 Jul;29(7):337-42. doi: 10.1016/j.it.2008.04.002. Epub 2008 May 29. Trends Immunol. 2008. PMID: 18514574 Review.
NCoR1 controls immune tolerance in conventional dendritic cells by fine-tuning glycolysis and fatty acid oxidation.
Sen K, Pati R, Jha A, Mishra GP, Prusty S, Chaudhary S, Swetalika S, Podder S, Sen A, Swain M, Nanda RK, Raghav SK. Sen K, et al. Redox Biol. 2023 Feb;59:102575. doi: 10.1016/j.redox.2022.102575. Epub 2022 Dec 16. Redox Biol. 2023. PMID: 36565644 Free PMC article.
The spleen of these infected animals also showed increased Th1-mediated responses in the inhibitor-treated group. These findings suggested strong involvement of NCoR1 in immune tolerance. ...Overall, for the first time, we demonstrated here that NCoR1 medi …
The spleen of these infected animals also showed increased Th1-mediated responses in the inhibitor-treated group. These findings sugg …
Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor.
Maj T, Wang W, Crespo J, Zhang H, Wang W, Wei S, Zhao L, Vatan L, Shao I, Szeliga W, Lyssiotis C, Liu JR, Kryczek I, Zou W. Maj T, et al. Nat Immunol. 2017 Dec;18(12):1332-1341. doi: 10.1038/ni.3868. Epub 2017 Oct 30. Nat Immunol. 2017. PMID: 29083399 Free PMC article.
Here we show that tumor T(reg) cells undergo apoptosis, and such apoptotic T(reg) cells abolish spontaneous and PD-L1-blockade-mediated antitumor T cell immunity. Biochemical and functional analyses show that adenosine, but not typical suppressive factors such as PD-L1, CT …
Here we show that tumor T(reg) cells undergo apoptosis, and such apoptotic T(reg) cells abolish spontaneous and PD-L1-blockade-mediated …
Urocanic acid and cutaneous antigen presentation.
Lappin MB, Simon JC. Lappin MB, et al. J Photochem Photobiol B. 1998 Jul 10;44(2):112-6. doi: 10.1016/S1011-1344(98)00129-8. J Photochem Photobiol B. 1998. PMID: 9757592 Review.
Exposure to UVB results in the isomerization of trans-urocanic acid (UCA), localized in the stratum corneum, to cis-UCA. Cis-UCA can mediate at least some of the immunosuppressive effects of UVB, though the mechanism of cis-UCA action remains incompletely defined. . …
Exposure to UVB results in the isomerization of trans-urocanic acid (UCA), localized in the stratum corneum, to cis-UCA. Cis-UCA can medi …
Tregs and transplantation tolerance.
Walsh PT, Taylor DK, Turka LA. Walsh PT, et al. J Clin Invest. 2004 Nov;114(10):1398-403. doi: 10.1172/JCI23238. J Clin Invest. 2004. PMID: 15545987 Free PMC article. Review.
The induction and maintenance of immune tolerance to transplanted tissues constitute an active process involving multiple mechanisms that work cooperatively to prevent graft rejection. These mechanisms are similar to inherent tolerance toward self antigens an …
The induction and maintenance of immune tolerance to transplanted tissues constitute an active process involving multiple mech …
Impaired inducibility of immune regulatory capacity of peripheral B cells of patients with recurrent pregnancy loss.
Ma F, Feng X, Feng S, Liu J, Li J, Mo L, Xu L, Liu Y, Wu J, Yang P, Ning Y. Ma F, et al. Immunol Res. 2024 Dec;72(6):1502-1514. doi: 10.1007/s12026-024-09549-7. Epub 2024 Nov 4. Immunol Res. 2024. PMID: 39495420
RPL may have an association with disruption of immune tolerance. The aim of this study is to characterize the inducibility of immune regulatory ability in peripheral naive B cells of patients with RPL. ...The effects of ER stress on reducing CMIP quantity in …
RPL may have an association with disruption of immune tolerance. The aim of this study is to characterize the inducibility of …
Interleukin-10 mediated immune regulation after stem cell transplantation: Mechanisms and implications for therapeutic intervention.
Zhang P, Hill GR. Zhang P, et al. Semin Immunol. 2019 Aug;44:101322. doi: 10.1016/j.smim.2019.101322. Epub 2019 Oct 19. Semin Immunol. 2019. PMID: 31640914 Review.
Interleukin-10 (IL-10) is a multi-faceted anti-inflammatory cytokine which plays an essential role in immune tolerance. ...Recently, intriguing interactions among IL-10, immune cells, commensal microbes and host tissues in the gastrointes …
Interleukin-10 (IL-10) is a multi-faceted anti-inflammatory cytokine which plays an essential role in immune toleran …
Immunosuppressive effect of progesterone on dendritic cells in mice.
Xu Y, He H, Li C, Shi Y, Wang Q, Li W, Song W. Xu Y, et al. J Reprod Immunol. 2011 Sep;91(1-2):17-23. doi: 10.1016/j.jri.2011.06.101. J Reprod Immunol. 2011. PMID: 21856019
Dendritic cells (DCs), the most potent triggers of the adaptive immune response, express receptors for steroid hormones and are regarded as one of the primary targets of progesterone. ...The observation that progesterone-treated DCs could attenuate delayed-type hype …
Dendritic cells (DCs), the most potent triggers of the adaptive immune response, express receptors for steroid hormones and ar …
Mechanisms underlying immunosuppression by regulatory cells.
Goldmann O, Nwofor OV, Chen Q, Medina E. Goldmann O, et al. Front Immunol. 2024 Feb 6;15:1328193. doi: 10.3389/fimmu.2024.1328193. eCollection 2024. Front Immunol. 2024. PMID: 38380317 Free PMC article. Review.
Regulatory cells, such as regulatory T cells (Tregs), regulatory B cells (Bregs), and myeloid-derived suppressor cells (MDSCs), play a crucial role in preserving immune tolerance and controlling immune responses during infections to prevent excessive …
Regulatory cells, such as regulatory T cells (Tregs), regulatory B cells (Bregs), and myeloid-derived suppressor cells (MDSCs), play a cruci …
2,060 results