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575 results

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Page 1
Autophagy and HIV.
Dinkins C, Arko-Mensah J, Deretic V. Dinkins C, et al. Semin Cell Dev Biol. 2010 Sep;21(7):712-8. doi: 10.1016/j.semcdb.2010.04.004. Epub 2010 Apr 18. Semin Cell Dev Biol. 2010. PMID: 20403451 Free PMC article. Review.
Autophagy is a key cytoplasmic biomass and organellar quality and quantity control pathway of the eukaryotic cell. ...Recent studies have shown that human immunodeficiency virus (HIV) is targeted for eliminated by autophagy but that this is countered by the v …
Autophagy is a key cytoplasmic biomass and organellar quality and quantity control pathway of the eukaryotic cell. ...Recent studies …
The Interplay of HIV and Autophagy in Early Infection.
Cabrera-Rodríguez R, Pérez-Yanes S, Estévez-Herrera J, Márquez-Arce D, Cabrera C, Espert L, Blanco J, Valenzuela-Fernández A. Cabrera-Rodríguez R, et al. Front Microbiol. 2021 Apr 28;12:661446. doi: 10.3389/fmicb.2021.661446. eCollection 2021. Front Microbiol. 2021. PMID: 33995324 Free PMC article. Review.
Confirming this interplay, strategies based on autophagy modulation are able to inhibit early steps of HIV-1 infection. Moreover, autophagy dysregulation in late steps of the HIV-1 replication cycle may promote autophagic cell-death of CD4(+) T cells o …
Confirming this interplay, strategies based on autophagy modulation are able to inhibit early steps of HIV-1 infection. Moreov …
Role of Autophagy in HIV-1 and Drug Abuse-Mediated Neuroinflammaging.
Sil S, Thangaraj A, Oladapo A, Hu G, Kutchy NA, Liao K, Buch S, Periyasamy P. Sil S, et al. Viruses. 2022 Dec 23;15(1):44. doi: 10.3390/v15010044. Viruses. 2022. PMID: 36680084 Free PMC article. Review.
Neuroinflammation is the hallmark feature of many neurodegenerative disorders, including HIV-1-associated neurocognitive disorders (HAND). Impaired autophagy has been identified as one of the underlying mechanisms of HAND in treated HIV-1-infected people that …
Neuroinflammation is the hallmark feature of many neurodegenerative disorders, including HIV-1-associated neurocognitive disorders (H …
The role of autophagy in the progression of HIV infected cardiomyopathy.
Sun Y, Xu M, Duan Q, Bryant JL, Xu X. Sun Y, et al. Front Cell Dev Biol. 2024 Jul 17;12:1372573. doi: 10.3389/fcell.2024.1372573. eCollection 2024. Front Cell Dev Biol. 2024. PMID: 39086659 Free PMC article. Review.
In this review, we consolidate, analyze, and discuss current research on the intersection between autophagy and HIVAC. Multiple studies have linked dysregulation in various regulators and functional components of autophagy to HIV infection regardless of mode …
In this review, we consolidate, analyze, and discuss current research on the intersection between autophagy and HIVAC. Multiple studi …
Endoplasmic reticulum stress and autophagy in HIV-1-associated neurocognitive disorders.
Chen X, Zhang T, Zhang Y. Chen X, et al. J Neurovirol. 2020 Dec;26(6):824-833. doi: 10.1007/s13365-020-00906-4. Epub 2020 Sep 11. J Neurovirol. 2020. PMID: 32918163 Review.
Although antiretroviral therapy (ART) affects virologic suppression and prolongs life expectancies among HIV-positive patients; HIV-1-associated neurocognitive disorders (HAND) continue to be diagnosed in patients with HIV-1 undergoing treatment. ...Through t …
Although antiretroviral therapy (ART) affects virologic suppression and prolongs life expectancies among HIV-positive patients; HI …
Pathogenesis of HIV-1 and Mycobacterium tuberculosis co-infection.
Bell LCK, Noursadeghi M. Bell LCK, et al. Nat Rev Microbiol. 2018 Feb;16(2):80-90. doi: 10.1038/nrmicro.2017.128. Epub 2017 Nov 7. Nat Rev Microbiol. 2018. PMID: 29109555 Review.
Co-infection with Mycobacterium tuberculosis is the leading cause of death in individuals infected with HIV-1. It has long been known that HIV-1 infection alters the course of M. tuberculosis infection and substantially increases the risk of active tuberculosis (TB) …
Co-infection with Mycobacterium tuberculosis is the leading cause of death in individuals infected with HIV-1. It has long been known …
Human TRIM5alpha: Autophagy Connects Cell-Intrinsic HIV-1 Restriction and Innate Immune Sensor Functioning.
Cloherty APM, Rader AG, Compeer B, Ribeiro CMS. Cloherty APM, et al. Viruses. 2021 Feb 19;13(2):320. doi: 10.3390/v13020320. Viruses. 2021. PMID: 33669846 Free PMC article. Review.
However, several recent studies underscore human TRIM5alpha as a cell-dependent HIV-1 restriction factor. Here, we present an overview of the latest research on human TRIM5alpha and propose a novel conceptualization of TRIM5alpha as a restriction factor with a varied portf …
However, several recent studies underscore human TRIM5alpha as a cell-dependent HIV-1 restriction factor. Here, we present an overvie …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)(1).
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R… See abstract for full author list ➔ Klionsky DJ, et al. Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. Autophagy. 2021. PMID: 33634751 Free PMC article.
Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukary …
Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite num …
LC3B conjugation machinery promotes autophagy-independent HIV-1 entry in CD4(+) T lymphocytes.
Pradel B, Cantaloube G, Villares M, Deffieu MS, Robert-Hebmann V, Lucansky V, Faure M, Chazal N, Gaudin R, Espert L. Pradel B, et al. Autophagy. 2024 Aug;20(8):1825-1836. doi: 10.1080/15548627.2024.2338573. Epub 2024 Apr 7. Autophagy. 2024. PMID: 38566318 Free PMC article.
Despite numerous studies investigating the HIV-1-autophagy interplays, the Atg8ylation impact in these early stages of infection remains unknown. ...Furthermore, we demonstrated that Atg8ylation is a key event facilitating HIV-1 entry in target CD4(+) T cells …
Despite numerous studies investigating the HIV-1-autophagy interplays, the Atg8ylation impact in these early stages of infecti …
Canonical and Non-Canonical Autophagy in HIV-1 Replication Cycle.
Leymarie O, Lepont L, Berlioz-Torrent C. Leymarie O, et al. Viruses. 2017 Sep 23;9(10):270. doi: 10.3390/v9100270. Viruses. 2017. PMID: 28946621 Free PMC article. Review.
As a consequence, HIV-1 has evolved different strategies to finely regulate the autophagy pathway to favor its replication and dissemination. ...This review outlines the current knowledge on the complex interplay between autophagy and HIV-1 replication …
As a consequence, HIV-1 has evolved different strategies to finely regulate the autophagy pathway to favor its replication and …
575 results