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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1987 3
1988 8
1989 4
1990 7
1991 8
1992 10
1993 15
1994 18
1995 19
1996 23
1997 23
1998 22
1999 20
2000 9
2001 16
2002 22
2003 23
2004 29
2005 35
2006 36
2007 42
2008 40
2009 35
2010 44
2011 55
2012 42
2013 56
2014 46
2015 39
2016 48
2017 46
2018 55
2019 52
2020 78
2021 64
2022 9
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1,032 results
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8 articles found by citation matching

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Page 1
TFOS DEWS II Definition and Classification Report.
Craig JP, Nichols KK, Akpek EK, Caffery B, Dua HS, Joo CK, Liu Z, Nelson JD, Nichols JJ, Tsubota K, Stapleton F. Craig JP, et al. Ocul Surf. 2017 Jul;15(3):276-283. doi: 10.1016/j.jtos.2017.05.008. Epub 2017 Jul 20. Ocul Surf. 2017. PMID: 28736335 Review.
The goals of the TFOS DEWS II Definition and Classification Subcommittee were to create an evidence-based definition and a contemporary classification system for dry eye disease (DED). The new definition recognizes the multifactorial nature of dry eye as a disease w …
The goals of the TFOS DEWS II Definition and Classification Subcommittee were to create an evidence-based definition and a contemporary clas …
New Perspectives on Dry Eye Definition and Diagnosis: A Consensus Report by the Asia Dry Eye Society.
Tsubota K, Yokoi N, Shimazaki J, Watanabe H, Dogru M, Yamada M, Kinoshita S, Kim HM, Tchah HW, Hyon JY, Yoon KC, Seo KY, Sun X, Chen W, Liang L, Li M, Liu Z; Asia Dry Eye Society. Tsubota K, et al. Ocul Surf. 2017 Jan;15(1):65-76. doi: 10.1016/j.jtos.2016.09.003. Epub 2016 Oct 8. Ocul Surf. 2017. PMID: 27725302 Free article. Review.
For the last 20 years, a great amount of evidence has accumulated through epidemiological studies that most of the dry eye disease encountered in daily life, especially in video display terminal (VDT) workers, involves short tear film breakup time (TFBUT) type dry eye
For the last 20 years, a great amount of evidence has accumulated through epidemiological studies that most of the dry eye disease en …
Violet light suppresses lens-induced myopia via neuropsin (OPN5) in mice.
Jiang X, Pardue MT, Mori K, Ikeda SI, Torii H, D'Souza S, Lang RA, Kurihara T, Tsubota K. Jiang X, et al. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2018840118. doi: 10.1073/pnas.2018840118. Proc Natl Acad Sci U S A. 2021. PMID: 34031241 Free PMC article.
The effects of a steam warming eye mask on the ocular surface and mental health.
Uchino M, Kawashima M, Yamanishi R, Inoue S, Kawashima S, Tagami K, Yoshida M, Sugita T, Uchino Y, Tsubota K. Uchino M, et al. Ocul Surf. 2021 Jul;21:129-133. doi: 10.1016/j.jtos.2021.05.007. Epub 2021 May 28. Ocul Surf. 2021. PMID: 34052414 Clinical Trial.
PURPOSE: The continuous use of warming eye masks improves tear function. In this double-blind randomized controlled trial, we aimed to analyze the effects of warming eye mask use on the ocular surface and mental health. METHODS: We enrolled 86 participants (age rang …
PURPOSE: The continuous use of warming eye masks improves tear function. In this double-blind randomized controlled trial, we aimed t …
Autoimmune Epithelitis and Chronic Inflammation in Sjögren's Syndrome-Related Dry Eye Disease.
Ogawa Y, Takeuchi T, Tsubota K. Ogawa Y, et al. Int J Mol Sci. 2021 Oct 30;22(21):11820. doi: 10.3390/ijms222111820. Int J Mol Sci. 2021. PMID: 34769250 Free PMC article. Review.
Autoimmune epithelitis and chronic inflammation are one of the characteristic features of the immune pathogenesis of Sjogren's syndrome (SS)-related dry eye disease. Autoimmune epithelitis can cause the dysfunction of the excretion of tear fluid and mucin from the lacrimal …
Autoimmune epithelitis and chronic inflammation are one of the characteristic features of the immune pathogenesis of Sjogren's syndrome (SS) …
Association between Retinal Nerve Fiber Layer Thickness and Eye Fatigue.
Ayaki M, Kuze M, Kondo M, Tsubota K, Negishi K. Ayaki M, et al. Biomed Res Int. 2019 Jan 23;2019:3014567. doi: 10.1155/2019/3014567. eCollection 2019. Biomed Res Int. 2019. PMID: 30809534 Free PMC article.
Eye fatigue is a common health problem across all age groups. Herein, we explored the correlation between eye fatigue and thickness of the retinal nerve fiber layer (NFL). ...The macular GCC was significantly thicker in subjects with eye fatigue compared to t
Eye fatigue is a common health problem across all age groups. Herein, we explored the correlation between eye fatigue and thic
Dry eye after refractive surgery.
Ang RT, Dartt DA, Tsubota K. Ang RT, et al. Curr Opin Ophthalmol. 2001 Aug;12(4):318-22. doi: 10.1097/00055735-200108000-00013. Curr Opin Ophthalmol. 2001. PMID: 11507347 Review.
Photorefractive keratectomy and laser in situ keratomileusis can induce or exacerbate dry eye after surgery. This manifests as an increase in degree and frequency of symptoms, corneal findings, such as superficial punctate keratopathy, and abnormal results of dry eye
Photorefractive keratectomy and laser in situ keratomileusis can induce or exacerbate dry eye after surgery. This manifests as an inc …
Glucose levels between the anterior chamber of the eye and blood are correlated based on blood glucose dynamics.
Kurihara T, Lee D, Shinojima A, Kinoshita T, Nishizaki S, Arita Y, Hidaka Y, Nishi Y, Shirakawa Y, Kimura S, Tsuneyoshi Y, Torii H, Tsubota K, Negishi K. Kurihara T, et al. PLoS One. 2021 Sep 1;16(9):e0256986. doi: 10.1371/journal.pone.0256986. eCollection 2021. PLoS One. 2021. PMID: 34469502 Free PMC article.
Frequent measurements of systemic glucose levels with prompt managements can prevent organ damages. The eye is a glucose highly demanding organ in our body, and the anterior chamber (AC) in the eye has been suggested for a noninvasive blood glucose monitoring site. …
Frequent measurements of systemic glucose levels with prompt managements can prevent organ damages. The eye is a glucose highly deman …
Tear dynamics and dry eye.
Tsubota K. Tsubota K. Prog Retin Eye Res. 1998 Oct;17(4):565-96. doi: 10.1016/s1350-9462(98)00004-4. Prog Retin Eye Res. 1998. PMID: 9777650 Review.
Even when there is adequate tear production, insufficient distribution, such as occurs with the decreased blinking associated with the use of video display terminals (VDT), may cause dry eye. Any process or activity that suppresses blinking interferes with tear distributio …
Even when there is adequate tear production, insufficient distribution, such as occurs with the decreased blinking associated with the use o …
1,032 results