Introduction: Vaccine hesitancy is a major challenge in controlling the COVID-19 pandemic, with healthcare professionals playing a major role in its acceptance.
Aim: To assess the acceptance of COVID-19 vaccines among health workers in Sidi Bel Abbès and to identify the psychological determinants of vaccination acceptance.
Methods: A descriptive cross-sectional study was conducted from December 01, 2021 to January 31, 2022 and involved health professionals in Sidi Bel Abbès, through an anonymous questionnaire. Psychological determinants were assessed using the 5C scale (15 items), whereas the Vaccine Conspiracy Beliefs Scale (VCBS) (7 items) was used to estimate the effect of vaccine conspiracy beliefs. 5C and VCBS scores were analyzed using the Receiver Operating Characteristic (ROC) curve.