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12 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Chlorhexidine gluconate vs povidone-iodine vaginal antisepsis for urogynecologic surgery: a randomized controlled noninferiority trial.
Rockefeller NF, Petersen TR, Komesu YM, Meriwether K, Dunivan G, Ninivaggio C, Jeppson PC. Rockefeller NF, et al. Am J Obstet Gynecol. 2022 Jul;227(1):66.e1-66.e9. doi: 10.1016/j.ajog.2021.12.260. Epub 2021 Dec 29. Am J Obstet Gynecol. 2022. PMID: 34973179 Clinical Trial.
BACKGROUND: Although povidone-iodine (iodine) is the only Food and Drug Administration-approved vaginal antiseptic solution, there is a lack of comparative data evaluating alternatives. Chlorhexidine gluconate is readily accessible, recommended by multiple so …
BACKGROUND: Although povidone-iodine (iodine) is the only Food and Drug Administration-approved vaginal antiseptic solu …
Tolerability and effectiveness of povidone-iodine or mupirocin versus saline sinus irrigations for chronic rhinosinusitis.
Lee VS, Pottinger PS, Davis GE. Lee VS, et al. Am J Otolaryngol. 2020 Sep-Oct;41(5):102604. doi: 10.1016/j.amjoto.2020.102604. Epub 2020 Jun 6. Am J Otolaryngol. 2020. PMID: 32563787 Free PMC article. Clinical Trial.
The objective was to compare povidone-iodine or mupirocin versus saline sinus irrigations for sinusitis exacerbations in post-surgery subjects as well as to assess tolerability of povidone-iodine sinus irrigations. ...There were no significant differen …
The objective was to compare povidone-iodine or mupirocin versus saline sinus irrigations for sinusitis exacerbations in post- …
The Effect of Povidone-Iodine Nasal Spray on Nasopharyngeal SARS-CoV-2 Viral Load: A Randomized Control Trial.
Zarabanda D, Vukkadala N, Phillips KM, Qian ZJ, Mfuh KO, Hatter MJ, Lee IT, Rao VK, Hwang PH, Domb G, Patel ZM, Pinsky BA, Nayak JV. Zarabanda D, et al. Laryngoscope. 2022 Nov;132(11):2089-2095. doi: 10.1002/lary.29935. Epub 2021 Nov 9. Laryngoscope. 2022. PMID: 34724213 Free PMC article. Clinical Trial.
OBJECTIVES/HYPOTHESIS: To determine the effect of povidone-iodine (PVP-I) nasal sprays on nasopharyngeal (NP) viral load as assessed by cycle threshold (Ct) on quantitative polymerase chain reaction (qPCR) of SARS-CoV-2 in outpatients. ...
OBJECTIVES/HYPOTHESIS: To determine the effect of povidone-iodine (PVP-I) nasal sprays on nasopharyngeal (NP) viral load as as …
A randomized trial of the bactericidal effects of chlorhexidine vs povidone-iodine vaginal preparation.
Duffy CR, Garcia-So J, Ajemian B, Gyamfi-Bannerman C, Han YW. Duffy CR, et al. Am J Obstet Gynecol MFM. 2020 Aug;2(3):100114. doi: 10.1016/j.ajogmf.2020.100114. Epub 2020 Apr 15. Am J Obstet Gynecol MFM. 2020. PMID: 33345865 Clinical Trial.
OBJECTIVE: We aimed to compare the bactericidal effect of chlorhexidine gluconate and povidone-iodine on vaginal bacterial colony counts in pregnancy. MATERIALS AND METHODS: We conducted a prospective randomized controlled trial of vaginal preparation with 0.5% chlo …
OBJECTIVE: We aimed to compare the bactericidal effect of chlorhexidine gluconate and povidone-iodine on vaginal bacterial col …
Efficacy of a Single Administration of 5% Povidone-Iodine in the Treatment of Adenoviral Conjunctivitis.
Than T, Morettin CE, Harthan JS, Hartwick ATE, Huecker JB, Johnson SD, Migneco MK, Shorter E, Whiteside M, Olson CK, Alferez CS, van Zyl T, Rodic-Polic B, Storch GA, Gordon MO. Than T, et al. Am J Ophthalmol. 2021 Nov;231:28-38. doi: 10.1016/j.ajo.2021.05.018. Epub 2021 Jun 6. Am J Ophthalmol. 2021. PMID: 34102153 Free PMC article. Clinical Trial.
PURPOSE: To evaluate the safety and efficacy of a single, in-office administration of 5% povidone-iodine (PVP-I) compared to artificial tears (AT) for adenoviral conjunctivitis (Ad-Cs). ...INCLUSION CRITERIA: 18 years of age, symptoms 4 days, and a positive AdenoPlu …
PURPOSE: To evaluate the safety and efficacy of a single, in-office administration of 5% povidone-iodine (PVP-I) compared to a …
Comparison of disinfection effect between benzalkonium chloride and povidone iodine in nasotracheal intubation: a randomized trial.
Sato-Boku A, Nagano K, Hasegawa Y, Kamimura Y, Sento Y, So M, Kako E, Okuda M, Tachi N, Ito H, Adachi Y, Sobue K. Sato-Boku A, et al. BMC Anesthesiol. 2019 Aug 31;19(1):168. doi: 10.1186/s12871-019-0839-y. BMC Anesthesiol. 2019. PMID: 31470798 Free PMC article. Clinical Trial.
RESULTS: Although the initial disinfection effects (B/A) were inferior for benzalkonium chloride compared with those for povidone iodine, the effects were sustained for benzalkonium chloride (C/B). In the in vitro growth inhibitory assay against S. aureus, benzalkon …
RESULTS: Although the initial disinfection effects (B/A) were inferior for benzalkonium chloride compared with those for povidone …
A clinical study on the tolerability of a liposomal povidone-iodine nasal spray: implications for further development.
Gluck U, Martin U, Bosse B, Reimer K, Mueller S. Gluck U, et al. ORL J Otorhinolaryngol Relat Spec. 2007;69(2):92-9. doi: 10.1159/000097758. Epub 2006 Dec 4. ORL J Otorhinolaryngol Relat Spec. 2007. PMID: 17148942 Clinical Trial.
PURPOSE OF STUDY: This phase I study assessed tolerability and local effect of a liposome dispersion with povidone-iodine (polyvinylpyrrolidone-iodine, PVP-I) as nasal spray. PROCEDURES: Three groups received liposomal dispersion with PVP-I (2.2, 4.4 and 0% a …
PURPOSE OF STUDY: This phase I study assessed tolerability and local effect of a liposome dispersion with povidone-iodine (pol …
Systemic metronidazole combined with either topical povidone-iodine or ampicillin in acute appendicitis.
Parker MC, Mathams A. Parker MC, et al. J Hosp Infect. 1985 Mar;6 Suppl A:97-101. doi: 10.1016/s0195-6701(85)80053-0. J Hosp Infect. 1985. PMID: 2860183 Clinical Trial.
One-hundred consecutive patients undergoing appendicectomy either electively or for clinically diagnosed acute appendicitis were studied to examine the difference between the use of topical povidone-iodine (PVP-I) and ampicillin in the wound given at the time of clo …
One-hundred consecutive patients undergoing appendicectomy either electively or for clinically diagnosed acute appendicitis were studied to …
Effect of Local Polyhexanide Application in Preventing Exit-Site Infection and Peritonitis: A Randomized Controlled Trial.
Ceri M, Yilmaz SR, Unverdi S, Kurultak I, Duranay M. Ceri M, et al. Ther Apher Dial. 2020 Feb;24(1):81-84. doi: 10.1111/1744-9987.12836. Epub 2019 Jul 7. Ther Apher Dial. 2020. PMID: 31066988 Clinical Trial.
ESI, tunnel infection, peritonitis, catheter removal and microorganism cause of catheter-related infection were recorded prospectively during clinic follow-up. A total of 88 patients (41 povidone-iodine group; 47 polyhexanide group) were enrolled with a total follow …
ESI, tunnel infection, peritonitis, catheter removal and microorganism cause of catheter-related infection were recorded prospectively durin …
Healing advantages of lavender essential oil during episiotomy recovery: a clinical trial.
Vakilian K, Atarha M, Bekhradi R, Chaman R. Vakilian K, et al. Complement Ther Clin Pract. 2011 Feb;17(1):50-3. doi: 10.1016/j.ctcp.2010.05.006. Epub 2010 Jun 17. Complement Ther Clin Pract. 2011. PMID: 21168115 Clinical Trial.
Case group received lavender oil and controls received povidone-iodine. Incision sites were assessed on the 10th day postpartum. 25 out of 60 women in lavender group and 17 mothers in control group had no pain (p = 0.06). ...This study suggests application of lavend …
Case group received lavender oil and controls received povidone-iodine. Incision sites were assessed on the 10th day postpartu …
12 results