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37913775,37761422,37731249,37532507,37401907,36803871,36502796,36233165,36087586,35361402,34933766,33964223,33494993,33203100,32863168,31195399,30954981,30800047,30168033,29419543,28891707,28209811,27538345,26947932,26860610,26591527,26248780,25449084,25385124,24698940,24632873,24471893,24412089,23545316,23194049,23074672,23000017,22482972,22398511,22209335,21574245,19679442,19399021,19135661,18970914,18371955,16331572,16155419,15861503,15372526,14673898,12838556,12438542,12438541,12116206,11165321,9370908,8591669,8362906,7847798,7784385,7573123,7507604,7319930,7037042,6714262,6510909,6450156,6345474,6335374,6331791,6228144,4075565,4061557,3815879,3733078,3568433,3564968,3499841,3474055,3236369,3160292,2960262,2887318,2741714,2648387,2369070,2253944,1346075,1308361,1242523,839502,278545,37106397,36931276,36857526,36806943,36709939,36454035,36316084,35946816,35822551,35737468,35678493,35451953,35248893,34995812,34974289,33927350,33885134,32791797,32663882,31897643,30990690,30990684,30922549,30632959,30279143,29782825,29367746,28912108,28640193,27367833,27188996,27079576,25968647,25398902,25125041,23678257,23671069,23363739,22911867,22775411,22628242,20709628,20420852,20420031,20131045,19778489,19775471,19060065,18813921,18761063,18665159,17352156,17135320,17002300,16215260,15862905,15850758,15755823,14527352,12237001,12107151,11811653,11477656,11455596,11418577,11384641,10507727,10076505,9545101,9335290,9261106,9091575,8613150,7959428,7672818,7640277,6572549,6238166,3495227,3348217,3011911,2944814,2921525,2790823,2549909,2546156,2363428,2019562,1909683,1860902,1791836,1424236,1349585,1214291,1154140,288487,133078,37990724,37971837,37952234,37932167,37757590,37728713,37725747,37586236,37541966,37461621,37448991,37447561,37405321,37400234,37292739,37220123,37200539,37198702,37184747,37169020,37151505,37112704,37094974,37034610,36976713,36951958,36901085,36896874,36864926,36818595,36759858,36728057,36704262,36587274,36585146,36508432,36400580,36380081,36266134,36238220,36231817,36195523,36099813,36059922,35801588,35587370,35500539,35489999,35422535,35364113,35186010,35156782,35147198,34940998,34871332,34866882,34861492,34712596,34670817,34656880,34600090,34575780,34511592,34485900,34416593,34333651,34269389,34216321,34212570,34209763,34152830,34031479,33885984,33860312,33802615,33564278,33561011,33528481,33356267,33346039,33316996,33280677,33170287,33063154,32980698,32941181,32824532,32743593,32720193,32717193,32658166,32592182,32587097,32525844,32303745,32292638,32284060,32238016,32206729,32155263,32003426,31985321,31978372,31907144,31837438,31788271,31695541,31470404,31383630,31360793,31334582,31239589,31234750,31034593,31021105,30997263,30960538,30952614,30688355,30587254,30576495,30449295,30264463,30195737,30180972,29767079,29721211,29654098,29600595,29334509,29100333,29053923,28934529,28871828,28867263,28791582,28779675,28734313,28518695,28517657,28517627,28517413,28422178,28398523,28332066,28315665,27966064,27816920,27782482,27459653,27459614,27440158,27228770,27182482,26965313,26665071,26291588,26248538,26000602,25903173,25812530,25788567,25743212,25682804,25678570,25426955,25320852,25157638,25147733,25041745,24940078,24836288,24649383,24506830,24451404,24445872,24395982,24342438,24134696,24069411,24044289,23842585,23706094,23498109,23288493,23002828,22951078,22608682,22413248,22404346,22124454,21957720,21919476,21784296,21744657,21526752,21306677,21230011,21146571,21037068,20960033,20728272,20405512,20029104,20006946,19881499,19552919,19308150,19288921,19262768,19029837,19005803,18564437,18516355,18324238,18043543,17824599,17028674,16729341,16584192,16539306,16431922,16271005,15888557,15841384,15659312,15491614,15122957,14977695,12962499,12944504,12913548,12164550,11815810,11770753,11762601,11447469,11348519,11322547,11035562,11002267,10753903,10521716,10231594,9933087,9719969,9687847,9680398,8654422,8377302,7966190,7888235,7872010,7836286,7545894,7019176,6332859,6303391,4015103,3989338,2963423,2909744,2859191,2395205,2344134,2324201,2020884,1890446,1571229,1387534,1313593,884078,38040695,38036523,38030596,38019873,38017640,38015176,38005938,38005849,38005825,38005818,38003325,38003278,37998322,37996444,37989731,37988472,37988468,37985666,37983521,37980366,37978413,37977350,37976320,37975542,37972068,37968443,37963876,37962168,37958905,37958786,37957154,37956352,37954975,37954612,37949851,37948320,37948264,37947593[uid]

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Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms.

Reinke S, Pantazi E, Chappell GR, Sanchez-Martinez A, Guyon R, Fergusson JR, Salman AM, Aktar A, Mukhopadhyay E, Ventura RA, Auderset F, Dubois PM, Collin N, Hill AVS, Bezbradica JS, Milicic A. Reinke S, et al. Cell Rep Med. 2023 Nov 21;4(11):101245. doi: 10.1016/j.xcrm.2023.101245. Epub 2023 Oct 31. Cell Rep Med. 2023. PMID: 37913775 Free PMC article.

Mimicking Hypoxic-Ischemic Encephalopathy in a Newborn with 21q Deletion Originating from Ring Chromosome 21.

Moon JU, Yum SK. Moon JU, et al. Children (Basel). 2023 Aug 27;10(9):1461. doi: 10.3390/children10091461. Children (Basel). 2023. PMID: 37761422 Free PMC article.

Molecular characterization of de novo ring chromosome 21 in a child with seizures, growth retardation, and multiple congenital anomalies.

Ambulkar PS, Liehr T, Jain M, Waghmare J, Gangane N, Narang P, Pal AK. Ambulkar PS, et al. J Genet. 2023;102:44. J Genet. 2023. PMID: 37731249 Free article.

[Clinical features and genetic analysis of two fetuses with ring chromosome 21 mosaicism].

Ji Y, Xu Y, Sun L, Ge Y, Cai M, Wu Q. Ji Y, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2023 Aug 10;40(8):1032-1035. doi: 10.3760/cma.j.cn511374-20220830-00589. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2023. PMID: 37532507 Chinese.

A rare ring chromosome 21 abnormality is associated with azoospermia in two different phenotypically normal cases.

Berkay EG, Karaman B, Başaran S. Berkay EG, et al. Syst Biol Reprod Med. 2023 Oct;69(5):387-393. doi: 10.1080/19396368.2023.2225682. Epub 2023 Jul 4. Syst Biol Reprod Med. 2023. PMID: 37401907

A novel high throughput plate-based method for 2-PE quantification in novel multidose vaccines (R21 malaria, Covishield and Covovax) and combination vaccines (Hexavalent).

Ranade D, Jena R, Patil K, Dogar V, Sancheti S, Deore V, Ashtagi S, Gairola S. Ranade D, et al. Vaccine. 2023 Mar 17;41(12):1979-1988. doi: 10.1016/j.vaccine.2023.02.039. Epub 2023 Feb 17. Vaccine. 2023. PMID: 36803871

B-Cell Acute Lymphoblastic Leukemia with iAMP21 in a Patient with Constitutional Ring Chromosome 21.

Baloda V, Aggarwal N, Rosado FG, Mackey S, Felker J, Yatsenko SA. Baloda V, et al. Cytogenet Genome Res. 2022;162(5):231-236. doi: 10.1159/000527025. Epub 2022 Dec 9. Cytogenet Genome Res. 2022. PMID: 36502796

Sequencing and Genomic Analysis of Sorghum DNA Introgression Variant Line R21 and Recipient Rice Jin Hui 1 Revealed Repetitive Element Variation.

Zhang T, Li X, Zhao Z, Wu R, Yang Z, He G. Zhang T, et al. Int J Mol Sci. 2022 Oct 6;23(19):11864. doi: 10.3390/ijms231911864. Int J Mol Sci. 2022. PMID: 36233165 Free PMC article.

Efficacy and immunogenicity of R21/Matrix-M vaccine against clinical malaria after 2 years' follow-up in children in Burkina Faso: a phase 1/2b randomised controlled trial.

Datoo MS, Natama HM, Somé A, Bellamy D, Traoré O, Rouamba T, Tahita MC, Ido NFA, Yameogo P, Valia D, Millogo A, Ouedraogo F, Soma R, Sawadogo S, Sorgho F, Derra K, Rouamba E, Ramos-Lopez F, Cairns M, Provstgaard-Morys S, Aboagye J, Lawrie A, Roberts R, Valéa I, Sorgho H, Williams N, Glenn G, Fries L, Reimer J, Ewer KJ, Shaligram U, Hill AVS, Tinto H. Datoo MS, et al. Lancet Infect Dis. 2022 Dec;22(12):1728-1736. doi: 10.1016/S1473-3099(22)00442-X. Epub 2022 Sep 7. Lancet Infect Dis. 2022. PMID: 36087586 Free article. Clinical Trial.

Prenatal diagnosis and molecular cytogenetic characterization of mosaic ring chromosome 21 associated with low PAPP-A and low PlGF in the first-trimester maternal serum screening.

Chen CP, Wang LK, Chern SR, Wu PS, Chen SW, Wu FT, Lee CC, Chen LF, Wang W. Chen CP, et al. Taiwan J Obstet Gynecol. 2022 Mar;61(2):359-363. doi: 10.1016/j.tjog.2022.02.029. Taiwan J Obstet Gynecol. 2022. PMID: 35361402 Free article.

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