Similar articles for PMID: 16023598

Year	Number of Results
1996	1
1998	1
1999	1
2001	3
2002	3
2003	5
2004	6
2005	11
2006	10
2007	19
2008	18
2009	18
2010	10
2011	11
2012	5
2013	11
2014	10
2015	19
2016	13
2017	4
2018	7
2019	9
2020	3
2021	7
2022	3
2023	1
2024	0

1

Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage.

Tao W, South VJ, Zhang Y, Davide JP, Farrell L, Kohl NE, Sepp-Lorenzino L, Lobell RB. Tao W, et al. Cancer Cell. 2005 Jul;8(1):49-59. doi: 10.1016/j.ccr.2005.06.003. Cancer Cell. 2005. PMID: 16023598 Free article.

2

An inhibitor of the kinesin spindle protein activates the intrinsic apoptotic pathway independently of p53 and de novo protein synthesis.

Tao W, South VJ, Diehl RE, Davide JP, Sepp-Lorenzino L, Fraley ME, Arrington KL, Lobell RB. Tao W, et al. Mol Cell Biol. 2007 Jan;27(2):689-98. doi: 10.1128/MCB.01505-06. Epub 2006 Nov 13. Mol Cell Biol. 2007. PMID: 17101792 Free PMC article.

3

Mcl-1 stability determines mitotic cell fate of human multiple myeloma tumor cells treated with the kinesin spindle protein inhibitor ARRY-520.

Tunquist BJ, Woessner RD, Walker DH. Tunquist BJ, et al. Mol Cancer Ther. 2010 Jul;9(7):2046-56. doi: 10.1158/1535-7163.MCT-10-0033. Epub 2010 Jun 22. Mol Cancer Ther. 2010. PMID: 20571074

4

Induction of apoptosis by monastrol, an inhibitor of the mitotic kinesin Eg5, is independent of the spindle checkpoint.

Chin GM, Herbst R. Chin GM, et al. Mol Cancer Ther. 2006 Oct;5(10):2580-91. doi: 10.1158/1535-7163.MCT-06-0201. Mol Cancer Ther. 2006. PMID: 17041103

5

Potentiation of kinesin spindle protein inhibitor-induced cell death by modulation of mitochondrial and death receptor apoptotic pathways.

Vijapurkar U, Wang W, Herbst R. Vijapurkar U, et al. Cancer Res. 2007 Jan 1;67(1):237-45. doi: 10.1158/0008-5472.CAN-06-2406. Cancer Res. 2007. PMID: 17210704

6

Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP.

Cox CD, Breslin MJ, Mariano BJ, Coleman PJ, Buser CA, Walsh ES, Hamilton K, Huber HE, Kohl NE, Torrent M, Yan Y, Kuo LC, Hartman GD. Cox CD, et al. Bioorg Med Chem Lett. 2005 Apr 15;15(8):2041-5. doi: 10.1016/j.bmcl.2005.02.055. Bioorg Med Chem Lett. 2005. PMID: 15808464

7

Bis(hetero)aryl derivatives as unique kinesin spindle protein inhibitors.

Matsuno K, Sawada J, Sugimoto M, Ogo N, Asai A. Matsuno K, et al. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1058-61. doi: 10.1016/j.bmcl.2009.01.018. Epub 2009 Jan 11. Bioorg Med Chem Lett. 2009. PMID: 19167222

8

Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.

Huang HC, Shi J, Orth JD, Mitchison TJ. Huang HC, et al. Cancer Cell. 2009 Oct 6;16(4):347-58. doi: 10.1016/j.ccr.2009.08.020. Cancer Cell. 2009. PMID: 19800579 Free PMC article.

9

Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20.

Morrow CJ, Tighe A, Johnson VL, Scott MI, Ditchfield C, Taylor SS. Morrow CJ, et al. J Cell Sci. 2005 Aug 15;118(Pt 16):3639-52. doi: 10.1242/jcs.02487. Epub 2005 Jul 26. J Cell Sci. 2005. PMID: 16046481

10

Conformation-dependent ligand regulation of ATP hydrolysis by human KSP: activation of basal hydrolysis and inhibition of microtubule-stimulated hydrolysis by a single, small molecule modulator.

Luo L, Carson JD, Molnar KS, Tuske SJ, Coales SJ, Hamuro Y, Sung CM, Sudakin V, Auger KR, Dhanak D, Jackson JR, Huang PS, Tummino PJ, Copeland RA. Luo L, et al. J Am Chem Soc. 2008 Jun 18;130(24):7584-91. doi: 10.1021/ja710889h. Epub 2008 May 21. J Am Chem Soc. 2008. PMID: 18491908

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