Similar articles for PMID: 16158929

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1

Intracellular glutathione levels determine cell sensitivity to apoptosis induced by the antineoplasic agent N-(4-hydroxyphenyl) retinamide.

Morales MC, Pérez-Yarza G, Nieto-Rementeria N, Boyano MD, Jangi M, Atencia R, Asumendi A. Morales MC, et al. Anticancer Res. 2005 May-Jun;25(3B):1945-51. Anticancer Res. 2005. PMID: 16158929 Free article.

2

Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation.

Kang MH, Wan Z, Kang YH, Sposto R, Reynolds CP. Kang MH, et al. J Natl Cancer Inst. 2008 Apr 16;100(8):580-95. doi: 10.1093/jnci/djn076. Epub 2008 Apr 8. J Natl Cancer Inst. 2008. PMID: 18398104

3

4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines.

Villani MG, Appierto V, Cavadini E, Bettiga A, Prinetti A, Clagett-Dame M, Curley RW, Formelli F. Villani MG, et al. Cancer Res. 2006 Mar 15;66(6):3238-47. doi: 10.1158/0008-5472.CAN-05-3362. Cancer Res. 2006. PMID: 16540676

4

4-HPR-mediated leukemia cell cytotoxicity is triggered by ceramide-induced mitochondrial oxidative stress and is regulated downstream by Bcl-2.

Morales MC, Pérez-Yarza G, Rementería NN, Boyano MD, Apraiz A, Gómez-Muñoz A, Pérez-Andrés E, Asumendi A. Morales MC, et al. Free Radic Res. 2007 May;41(5):591-601. doi: 10.1080/10715760701218558. Free Radic Res. 2007. PMID: 17454142

5

Hypoxia-mediated fenretinide (4-HPR) resistance in childhood acute lymphoblastic leukemia cells.

Yang B, Fan L, Fang L, He Q. Yang B, et al. Cancer Chemother Pharmacol. 2006 Oct;58(4):540-6. doi: 10.1007/s00280-006-0197-6. Epub 2006 Mar 7. Cancer Chemother Pharmacol. 2006. PMID: 16520989

6

Fenretinide cytotoxicity for Ewing's sarcoma and primitive neuroectodermal tumor cell lines is decreased by hypoxia and synergistically enhanced by ceramide modulators.

Batra S, Reynolds CP, Maurer BJ. Batra S, et al. Cancer Res. 2004 Aug 1;64(15):5415-24. doi: 10.1158/0008-5472.CAN-04-0377. Cancer Res. 2004. PMID: 15289350

7

Antagonism of buthionine sulfoximine cytotoxicity for human neuroblastoma cell lines by hypoxia is reversed by the bioreductive agent tirapazamine.

Yang B, Keshelava N, Anderson CP, Reynolds CP. Yang B, et al. Cancer Res. 2003 Apr 1;63(7):1520-6. Cancer Res. 2003. PMID: 12670899

8

N-(4-hydroxyphenyl)retinamide induces apoptosis of malignant hemopoietic cell lines including those unresponsive to retinoic acid.

Delia D, Aiello A, Lombardi L, Pelicci PG, Grignani F, Grignani F, Formelli F, Menard S, Costa A, Veronesi U, et al. Delia D, et al. Cancer Res. 1993 Dec 15;53(24):6036-41. Cancer Res. 1993. PMID: 8261419

9

Cellular redox state and its relationship to the inhibition of clonal cell growth and the induction of apoptosis during all-trans retinoic acid exposure in acute myeloblastic leukemia cells.

Mäntymaa P, Guttorm T, Siitonen T, Säily M, Savolainen ER, Levonen AL, Kinnula V, Koistinen P. Mäntymaa P, et al. Haematologica. 2000 Mar;85(3):238-45. Haematologica. 2000. PMID: 10702810

10

Mediation of N-(4-hydoxyphenyl)retinamide-induced apoptosis in human cancer cells by different mechanisms.

Sun SY, Li W, Yue P, Lippman SM, Hong WK, Lotan R. Sun SY, et al. Cancer Res. 1999 May 15;59(10):2493-8. Cancer Res. 1999. PMID: 10344763

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