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18299547,17472818,15249352,17095906,17884359,16875966,19781407,16308988,17719314,16356805,16784936,18519851,21385791,19369876,18042049,16126025,17000936,16116054,19166691,16226163,18326948,18187070,18427276,21067804,17826369,17826370,15882678,16126023,19796735,18266852,19733714,19371188,19318984,17993807,18506053,17986516,8647574,18772061,18702965,19281914,15121997,20825761,19281915,17712042,25579834,17452609,16996863,19318387,18523323,16755211,15465509,15262025,16126024,19142597,16606817,19222610,16490577,19332231,19103995,23932462,17599422,20653359,18402899,16636231,20208032,19660594,17126675,19161879,17664373,17700016,17159064,19394473,19185092,19576317,19022156,18480348,17679135,15756346,19786883,19638365,18545068,18804740,16352778,17512355,16291009,17035507,18343268,17679130,16286171,17042674,16820364,18725490,18489938,25881936,17950146,16824830,18359323,17954357,15211327,20979581,16098383,16820596,25473831,18793814,18078013,16009795,19637943,12966660,16214597,23895811,18343245,22607822,17599426,17531574,19125895,19496269,23323878,18436114,18158500,17596685,15739256,17010789,16401005,17719318,30073316,17355737,17875946,20215906,16729010,16139139,22307462,16832166,17993806,27673306,16356804,27388482,27477773,17399827,17872880,24272891,15784644,16613195,18237593,16222621,23942733,21925056,25122464,18178406,22026393,22639397,19302897,16847150,18174034,15613464,16950174,21489086,16670413,11770860,15276569,21636154,15089818,15199449,17466224,9972199,22322620,18069223,25979868,22187291,21797655,15993392,17277349,20083825,23674398,19574923,16483333,20403481,22845871,16784935,15149060,18001320,16961668,18187072,21806315,16644313,18036362,12116678,16755194,7551266,18215600,16810040,17655954,30712900,22295883,22697390,21411487,16126019,15066683,11223487,21693744,16945051,16874355,20843566,23324122,11808441,20720485,17064710,17095907,14615806,15172626,17896892,12422725,22914531,15983909,16118493,21193682,22874885,22840347,22189667,17165243,16308999,21438814,16169318,16581337,15711645,12574894,21146668,17206389,22064595,18266994,8321785,18086071,24698458,17460552,22836065,21211613,15533640,25456820,17934205,12966652,26306625,24601937,12884938,15151477,19766762,17921739,23427811,20638223,17765048,21146667,20167359,17503884,17972032,16493575,24157192,18199996,30557296,15208802,16805758,8615707,22495163,18522792,22588266,23903772,17130382,17215087,19210138,26658282,16581336,23482733,26115069,27919293,17099339,28506385,17192126,23083789,25001154,16126018,19817511,16503095,28504565,31756624,25620142,17615773,26442621,17042673,23524091,17391425,7802520,26526340,19556725,16949689,29617981,26160634,17892981,28781026,15999505,11760542,10612322,16446226,27488607,17196453,25369120,17697899,25372483,17259710,14564314,15172426,22276132,22735112,22910758,15776029,17389664,16276235,20535009,17242008,28071756,28509674,15928286,26487187,21291679,25971444,31901256,30903687,11520485,22192281,23540819,24560324,22732520,25498191,17765049,24161323,16581333,20723656,17577297,24434254,29552926,15651087,20671371,18035919,21353894,25435519,26303789,19730842,17993998,7483643,12836863,11694218,18258828,17053373,17728542,16674357,21295870,25440725,20138279,15296701,22487773,27684837,20196891,23700132,19933787,17126679,23539920,27272576,28779871,16049521,29310996,27227451,27771711,21353895,21491736,16490432,27009446,20667950,19343119,25744012,16635411,18514660,10632823,22868819,22824348,12215193,19895944,25881937,21177073,17940676,12708634,24624458,24902972,18097177,25425404,17620857,16989592,29580713,15987626,27058862,15478041,24524615,17679133,27719645,23099278,27545127,16572517,31411090,32660417,17909373,15613049,23423521,25526798,23973042,31514949,29561426,30782002,27038725,15296706,11833452,16674359,18480653,10855251,19817526,18276612,25446168,23129439,24902973,24484462,21404720,25479530,17167932,16167397,17493093,17509947,29693013,26443250,28373930,15670548,24618241,12441887,31286992,32829708,31876797,22790192,31865057,21447948,19875196,17986513,32821711,31651893,32194896,27725093,16932325,17001067,31942495,29770157,24720455,17408521,22938925,16564763,26655539,16581335,27264221,10867329,17131313,12377727,10555448,27029774,30396516,31554462,21649973,23001065,29754126,17689740,23933855,27551034,24425060,16250088,16265333,17357442,9766341,17223421,31496436,27838696,31609450,21446900,17538581,25126293,17032570,25451341,12469578,18237570,11959517,11711271,25614425,18289652,17980261,15458932,32133735,26152775,16927604,9972112,17926484,18256681,18261479,28750707,15748229,12966373,12109460,16530675,31441063,31441055,22995416,28024088,25424136,17080973,21268569,31017615,22430424,20704039,16810165,11139823,16530693,18161392,20597192,15644844,16379995,18232109,21949257,15883402,21576521,17063162,12556756,16379020,17169239,16753528,31265824,16379951,31539045,16379913,16380043,16929375,17245322,32792087,30123546,32498805,21692611,31124739,18059384[uid]

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Results by year

Year	Number of Results
1993	1
1994	1
1995	3
1996	2
1998	4
1999	5
2000	2
2001	8
2002	11
2003	9
2004	22
2005	47
2006	70
2007	79
2008	51
2009	34
2010	26
2011	28
2012	32
2013	28
2014	26
2015	27
2016	21
2017	11
2018	13
2019	19
2020	12

545 results

Results by year

Page 1

The efficacy and safety of intensive statin therapy: a meta-analysis of randomized trials.

Josan K, Majumdar SR, McAlister FA. Josan K, et al. CMAJ. 2008 Feb 26;178(5):576-84. doi: 10.1503/cmaj.070675. CMAJ. 2008. PMID: 18299547 Free PMC article.

Meta-analysis of drug-induced adverse events associated with intensive-dose statin therapy.

Silva M, Matthews ML, Jarvis C, Nolan NM, Belliveau P, Malloy M, Gandhi P. Silva M, et al. Clin Ther. 2007 Feb;29(2):253-60. doi: 10.1016/j.clinthera.2007.02.008. Clin Ther. 2007. PMID: 17472818

Effectiveness of statin therapy in adults with coronary heart disease.

Wilt TJ, Bloomfield HE, MacDonald R, Nelson D, Rutks I, Ho M, Larsen G, McCall A, Pineros S, Sales A. Wilt TJ, et al. Arch Intern Med. 2004 Jul 12;164(13):1427-36. doi: 10.1001/archinte.164.13.1427. Arch Intern Med. 2004. PMID: 15249352 Review.

The safety and efficacy of achieving very low LDL-cholesterol concentrations with high dose statin therapy.

Wiviott SD, Cannon CP. Wiviott SD, et al. Curr Opin Lipidol. 2006 Dec;17(6):626-30. doi: 10.1097/MOL.0b013e328010872d. Curr Opin Lipidol. 2006. PMID: 17095906 Review.

Effect of intensive lipid-lowering therapy on mortality after acute coronary syndrome (a patient-level analysis of the Aggrastat to Zocor and Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 trials).

Murphy SA, Cannon CP, Wiviott SD, de Lemos JA, Blazing MA, McCabe CH, Califf RM, Braunwald E. Murphy SA, et al. Am J Cardiol. 2007 Oct 1;100(7):1047-51. doi: 10.1016/j.amjcard.2007.04.053. Epub 2007 Jul 18. Am J Cardiol. 2007. PMID: 17884359 Clinical Trial.

Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy.

Cannon CP, Steinberg BA, Murphy SA, Mega JL, Braunwald E. Cannon CP, et al. J Am Coll Cardiol. 2006 Aug 1;48(3):438-45. doi: 10.1016/j.jacc.2006.04.070. Epub 2006 Jul 12. J Am Coll Cardiol. 2006. PMID: 16875966 Free article.

Rationale and design of China intensive lipid lowering with statins in acute coronary syndrome: the CHILLAS study.

Zhao SP, Peng DQ, Yu BL, Huo Y; CHILLAS investigators. Zhao SP, et al. Am Heart J. 2009 Oct;158(4):509-512.e1. doi: 10.1016/j.ahj.2009.07.030. Am Heart J. 2009. PMID: 19781407 Clinical Trial.

The intensive statin therapy myth.

Shechter M, Beigel R, Matetzky S, Freimark D, Chouraqui P. Shechter M, et al. Isr Med Assoc J. 2005 Nov;7(11):683-7. Isr Med Assoc J. 2005. PMID: 16308988 Free article. Review.

Safety and efficacy of Atorvastatin-induced very low-density lipoprotein cholesterol levels in Patients with coronary heart disease (a post hoc analysis of the treating to new targets [TNT] study).

LaRosa JC, Grundy SM, Kastelein JJ, Kostis JB, Greten H; Treating to New Targets (TNT) Steering Committee and Investigators. LaRosa JC, et al. Am J Cardiol. 2007 Sep 1;100(5):747-52. doi: 10.1016/j.amjcard.2007.03.102. Epub 2007 Jun 14. Am J Cardiol. 2007. PMID: 17719314 Clinical Trial.

Improved outcome after acute coronary syndromes with an intensive versus standard lipid-lowering regimen: results from the Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22) trial.

Rouleau J. Rouleau J. Am J Med. 2005 Dec;118 Suppl 12A:28-35. doi: 10.1016/j.amjmed.2005.09.014. Am J Med. 2005. PMID: 16356805