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19414389,19445542,18509748,17312464,18162154,19487987,17213816,16552951,17147109,19838207,18376310,16229017,18853324,18559540,18767037,22041818,17671207,15240510,17255315,17143338,18400834,24535079,17496931,16552335,18575319,18027712,19132225,16432534,18575320,17410536,18218209,18283716,11522653,15730651,15913932,23076497,18453222,16940187,18781596,15820061,17487403,17272744,17121229,18978810,18359679,20952681,16532342,19293442,23467940,20659427,17985331,19080330,18421307,22487528,16452228,20432243,22960198,21187066,22227185,18314260,17289897,18240292,18498249,15854533,17683079,19671674,19212630,17321542,22086003,24795051,17932320,15719438,19166937,18381421,17609869,15930287,22214699,17473215,18478929,19082468,18695876,18289474,18341590,15234817,18952656,20564420,18773881,18316784,18602210,20980400,16096651,22196409,25955241,19180921,24912640,18670359,23377827,21964646,21119667,19118548,17343848,22924580,19254699,16408291,19184477,18158998,17561118,19426600,18050252,17577739,22982617,22367292,19040022,18570733,17409425,16077932,19102499,16438736,25853522,18438939,19694616,18273056,17637739,18597088,17885582,23087365,19790065,19347278,15925386,26066603,18658046,16998220,18277677,17255327,18258605,19080496,16404516,19520152,26002039,19540595,17591907,22115707,15850830,18497950,16374551,21514280,21653687,19010893,19074877,16253768,17610843,28000883,19440000,19816521,22343340,19149949,18202112,18818708,17442180,18550099,16336399,23085511,19409914,22805025,19291710,19196508,15862307,21401803,23924606,21412184,19549902,18618239,19299748,22521642,18381954,17166886,16440321,20080132,16924239,19428442,17560552,18854835,18327814,19038366,25575055,24860939,19712049,17645840,18204076,22470047,16497877,18202779,16628653,16684536,11931708,19456861,18996094,20139176,16882692,17920759,21421285,18307948,21950556,21617867,19496172,19077164,20138114,20705587,21575495,18930717,15694029,19595151,17499866,18842680,18379592,18089796,16383033,18478184,22126773,22245592,17920049,18813785,30099443,14989824,18518662,19912316,23001853,17563752,20194722,20032407,18954936,26715508,17914567,17579787,19235921,16305953,21701041,15969046,18998463,19141292,24677016,18792019,19461054,17008771,17409444,16111722,16301840,25847716,17998062,19595685,18359286,19171477,20684259,16998831,17273746,19549930,18393939,19302817,18353538,19077391,24561986,18752464,19735291,26739387,19418226,22948784,25823824,16277894,12821113,18538669,19431154,18459142,15811753,19276252,17445471,19106818,25119596,18062270,24083758,17332917,18983642,23322610,18675125,24788198,16489407,18535621,19723087,22883954,19160097,21778785,18097583,21642357,21887310,21485199,16077980,18418234,16357173,18497946,19490965,19369471,19304510,30597662,19574782,23311761,17916190,19094539,19811731,18514274,18720042,17944672,19218102,26350185,19167456,18588890,18725048,15862159,29031476,16388744,18996491,21586227,18026974,18514219,24316875,22672828,16791480,17340152,37861358,25710281,21168750,25824695,15960883,21437769,24129188,18298898,27431814,30381665,17064467,17983496,18835019,19106745,25017576,18474255,27061137,30827134,15300796,16456580,17201127,27098619,17316997,29267502,26467924,16774947,28476028,19229880,29881400,29770329,17363587,20723413,23615397,17885826,18535160,23475695,23339102,24022164,24338218,20637078,30402847,17222798,18463201,21158113,25051115,22833345,19387079,19048601,19760195,21167650,16762860,15979406,17074018,18432192,18575318,26730155,20637781,21849124,17786371,27363270,18214615,37440157,20705058,15694030,35659362,18358626,16822500,17167722,23740244,19398263,25385144,16533170,19892878,18408768,19024322,22524809,28712397,30121641,15958300,22859272,24690177,27485543,32510153,19461932,22883454,20924188,18971183,23228632,29207048,25068796,16494782,26576476,18762366,16000563,18036326,22753248,21537326,22482968,19435817,17264304,22075557,19062732,19414801,22453051,18088509,17533374,20706634,18614215,19258503,12605983,32312328,19370348,23158987,26350953,19403415,34229478,19414365,18042375,17416447,24746137,16409758,19004544,18511933,20865400,18813821,21177188,19263436,19036417,32886165,16773199,19254710,17256467,38571352,18715881,19247578,38634741,17548926,38118310,17998070,19236545,19494838,24253102,22905613,30528714,23359428,19287337,17476462,26323527,24486403,22738794,16274703,21733372,25339014,20556833,20021945,23549264,21925591,23529241,19277508,18819928,24237301,21856340,29030089,23900566,24761676,18437082,20137345,16964404,19101986,21724378,17885676,19351861,19670328,28444885,11766384,32420378,18957617,24042437,16889436,21149600,19036014,24286852,18447926,18028765,25305321,20409762,17027001,23591012,32835935,23726431,21220916,18846111,21050481,15890996,25987665,26745120,22901169,12535735,30340459,19084604,29535421,20813154,23447002,20037603,19386602,21163055,25973060,18437038,26711814,19233129,19123465,25760590,25734830,19024324,19383898,26657503,16468329,28586054,19303878,19180958,28558056,20825717,16628086,19381167,16834911,19394420,16712983,28838387,25744540,24709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852 results

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siRNA targeting HIF-1alpha induces apoptosis of pancreatic cancer cells through NF-kappaB-independent and -dependent pathways under hypoxic conditions.

Chen C, Yu Z. Chen C, et al. Anticancer Res. 2009 Apr;29(4):1367-72. Anticancer Res. 2009. PMID: 19414389 Free article.

Effect of siRNA targeting HIF-1alpha combined L-ascorbate on biological behavior of hypoxic MiaPaCa2 cells.

Chen C, Tang P, Yue J, Ren P, Liu X, Zhao X, Yu Z. Chen C, et al. Technol Cancer Res Treat. 2009 Jun;8(3):235-40. doi: 10.1177/153303460900800309. Technol Cancer Res Treat. 2009. PMID: 19445542 Free article.

Effect of small interference RNA targeting HIF-1alpha mediated by rAAV combined L: -ascorbate on pancreatic tumors in athymic mice.

Chen C, Sun J, Liu G, Chen J. Chen C, et al. Pathol Oncol Res. 2009 Mar;15(1):109-14. doi: 10.1007/s12253-008-9063-7. Epub 2008 May 29. Pathol Oncol Res. 2009. PMID: 18509748 Free article.

Effects of YC-1 on hypoxia-inducible factor 1-driven transcription activity, cell proliferative vitality, and apoptosis in hypoxic human pancreatic cancer cells.

Zhao Q, Du J, Gu H, Teng X, Zhang Q, Qin H, Liu N. Zhao Q, et al. Pancreas. 2007 Mar;34(2):242-7. doi: 10.1097/01.mpa.0000250135.95144.b6. Pancreas. 2007. PMID: 17312464

[Impact of RNA interference targeting hypoxia-inducible factor-1alpha on chemosensitivity in esophageal squamous cell carcinoma cells under hypoxia].

Wu XA, Sun Y, Fan QX, Wang LX, Wang RL, Zhang L. Wu XA, et al. Zhonghua Yi Xue Za Zhi. 2007 Oct 9;87(37):2640-4. Zhonghua Yi Xue Za Zhi. 2007. PMID: 18162154 Chinese.

Moscatilin repressed lipopolysaccharide-induced HIF-1alpha accumulation and NF-kappaB activation in murine RAW264.7 cells.

Liu YN, Pan SL, Peng CY, Huang DY, Guh JH, Chen CC, Shen CC, Teng CM. Liu YN, et al. Shock. 2010 Jan;33(1):70-5. doi: 10.1097/SHK.0b013e3181a7ff4a. Shock. 2010. PMID: 19487987

YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia.

Sun HL, Liu YN, Huang YT, Pan SL, Huang DY, Guh JH, Lee FY, Kuo SC, Teng CM. Sun HL, et al. Oncogene. 2007 Jun 7;26(27):3941-51. doi: 10.1038/sj.onc.1210169. Epub 2007 Jan 8. Oncogene. 2007. PMID: 17213816

[Inhibitory effect of siRNA targeting HIF-1alpha on differentiation of peripheral blood endothelial progenitor cells].

Jiang M, Wang CQ, Wang BY, Huang DJ. Jiang M, et al. Ai Zheng. 2005 Nov;24(11):1293-300. Ai Zheng. 2005. PMID: 16552951 Chinese.

[Inhibitory effect of YC-1 on induction of VEGF and GPI genes in hypoxic human pancreatic cancer cells].

Du J, Zhao Q, Gu H, Teng XL, Qin H, Liu NZ. Du J, et al. Zhonghua Zhong Liu Za Zhi. 2006 Jul;28(7):486-9. Zhonghua Zhong Liu Za Zhi. 2006. PMID: 17147109 Chinese.

Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-kappaB activity in hypoxic tumor cells.

Jang GY, Jeon JH, Cho SY, Shin DM, Kim CW, Jeong EM, Bae HC, Kim TW, Lee SH, Choi Y, Lee DS, Park SC, Kim IG. Jang GY, et al. Oncogene. 2010 Jan 21;29(3):356-67. doi: 10.1038/onc.2009.342. Epub 2009 Oct 19. Oncogene. 2010. PMID: 19838207

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