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Similar articles for PMID: 21149489

109 results

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Page 1
Mixed-affinity binding in humans with 18-kDa translocator protein ligands.
Owen DR, Gunn RN, Rabiner EA, Bennacef I, Fujita M, Kreisl WC, Innis RB, Pike VW, Reynolds R, Matthews PM, Parker CA. Owen DR, et al. J Nucl Med. 2011 Jan;52(1):24-32. doi: 10.2967/jnumed.110.079459. Epub 2010 Dec 13. J Nucl Med. 2011. PMID: 21149489 Free PMC article.
11C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain.
Ikawa M, Lohith TG, Shrestha S, Telu S, Zoghbi SS, Castellano S, Taliani S, Da Settimo F, Fujita M, Pike VW, Innis RB; Biomarkers Consortium Radioligand Project Team. Ikawa M, et al. J Nucl Med. 2017 Feb;58(2):320-325. doi: 10.2967/jnumed.116.178996. Epub 2016 Nov 17. J Nucl Med. 2017. PMID: 27856631 Free PMC article.
An 18-kDa translocator protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28.
Owen DR, Yeo AJ, Gunn RN, Song K, Wadsworth G, Lewis A, Rhodes C, Pulford DJ, Bennacef I, Parker CA, StJean PL, Cardon LR, Mooser VE, Matthews PM, Rabiner EA, Rubio JP. Owen DR, et al. J Cereb Blood Flow Metab. 2012 Jan;32(1):1-5. doi: 10.1038/jcbfm.2011.147. Epub 2011 Oct 19. J Cereb Blood Flow Metab. 2012. PMID: 22008728 Free PMC article.
Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker.
Kreisl WC, Fujita M, Fujimura Y, Kimura N, Jenko KJ, Kannan P, Hong J, Morse CL, Zoghbi SS, Gladding RL, Jacobson S, Oh U, Pike VW, Innis RB. Kreisl WC, et al. Neuroimage. 2010 Feb 15;49(4):2924-32. doi: 10.1016/j.neuroimage.2009.11.056. Epub 2009 Dec 4. Neuroimage. 2010. PMID: 19948230 Free PMC article.
Determination of [(11)C]PBR28 binding potential in vivo: a first human TSPO blocking study.
Owen DR, Guo Q, Kalk NJ, Colasanti A, Kalogiannopoulou D, Dimber R, Lewis YL, Libri V, Barletta J, Ramada-Magalhaes J, Kamalakaran A, Nutt DJ, Passchier J, Matthews PM, Gunn RN, Rabiner EA. Owen DR, et al. J Cereb Blood Flow Metab. 2014 Jun;34(6):989-94. doi: 10.1038/jcbfm.2014.46. Epub 2014 Mar 19. J Cereb Blood Flow Metab. 2014. PMID: 24643083 Free PMC article. Clinical Trial.
A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation.
Kreisl WC, Jenko KJ, Hines CS, Lyoo CH, Corona W, Morse CL, Zoghbi SS, Hyde T, Kleinman JE, Pike VW, McMahon FJ, Innis RB; Biomarkers Consortium PET Radioligand Project Team. Kreisl WC, et al. J Cereb Blood Flow Metab. 2013 Jan;33(1):53-8. doi: 10.1038/jcbfm.2012.131. Epub 2012 Sep 12. J Cereb Blood Flow Metab. 2013. PMID: 22968319 Free PMC article.
Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands.
Pike VW, Taliani S, Lohith TG, Owen DR, Pugliesi I, Da Pozzo E, Hong J, Zoghbi SS, Gunn RN, Parker CA, Rabiner EA, Fujita M, Innis RB, Martini C, Da Settimo F. Pike VW, et al. J Med Chem. 2011 Jan 13;54(1):366-73. doi: 10.1021/jm101230g. Epub 2010 Dec 6. J Med Chem. 2011. PMID: 21133364 Free PMC article.
109 results