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21176169,23535911,22719190,20684021,20648474,30762732,21319195,27059980,24349054,23872669,21381068,28975533,34321850,24119744,22719876,23416328,25543233,22258181,26229402,25069572,32811452,22141340,23512881,24477042,21488075,20373368,28554682,22898488,23734760,23418085,26485523,23269818,31519069,25522307,25801076,32145261,31054980,26605757,31945251,25240529,24607626,29258449,25646328,27836992,28744823,27150500,23032985,27015186,25641744,32298765,34749354,33306506,21254164,31419571,25791171,33200017,32035968,26599080,20546964,27615511,31677195,34490745,26765961,29396131,24417250,21168155,29055919,29578593,21745286,30444569,21745282,22863562,29469042,27752939,22546774,30912854,25040896,35143946,28253210,22314430,19738004,26610348,29307798,20648472,32220085,27908400,26148225,21665509,25429378,22869157,26259026,25290313,25302781,32342668,26760234,35829867,30176114,29601441,31642820,29193269,34076851,31377187,19651814,23155331,36897668,33905771,35836754,20803499,23226254,32561908,21281435,27905898,30132178,26419236,20826584,22629460,34297902,29271184,36079710,23800943,31250467,33685085,35833455,23776098,24707151,31896166,25876871,23484035,21334404,21423719,24069270,35710086,37149016,23334462,24458218,35881683,26200108,22792295,34506332,34808618,23176674,25018854,26136587,33024398,36878430,24123231,30161167,35349726,34839623,26139292,31304703,36049612,32871288,35831700,34147109,35949720,36110512,36206762,34276153,34610207,36758837,24155878,34557398,35189385,34280991,21953442,34833467,24498332,22140488,24691744,25232397,35076162,28797039,23804528,32592869,23977033,34504179,35560106,33532620,30852978,29474507,33896117,24621583,31546054,23837136,35630668,34482352,35023183,36166317,36403577,24978903,28497593,24114809,27537584,21525193,32360822,24445574,35020496,24642579,35528982,23236228,35599930,35100585,29595690,33956487,20708005,23594525,20648554,23894275,27527746,32104030,34718870,26850495,36908183,29493856,25597287,36555467,35218194,33249617,32882372,22182810,21042922,34137937,32841307,23740153,29562163,36264206,34609305,25180867,36881106,32039370,28950858,33922278,36719059,22065161,24917523,18546525,33800964,32454036,21987293,34904923,25438866,22215535,22328022,24360992,34962148,35333773,34535985,33616244,36448439,32882427,22952180,34607067,26343796,36944955,27572914,28436986,23564467,34031913,33704100,33279778,24061205,32463622,24124336,35733806,23110056,36359239,20625834,35092912,33565643,21206486,21494074,19880582,34558842,34933429,20962157,34258604,35486295,36367682,35330730,23477746,31548436,25676803,28544258,20375640,32987175,35713614,36615809,30539516,34261618,26632897,23815500,22384523,24342745,23275357,31695245,21228496,33856023,33444683,24799990,31965669,20852027,22129796,33105679,33860118,32247823,35365950,25974139,35654975,20825652,34476902,22331365,26457389,33728819,34184762,35625751,22582214,22876027,23849554,32396414,31511022,22959976,36266438,22343513,23900558,34843158,26418083,36544609,36386790,35475755,34902334,36627697,35124268,31960587,34007801,34524608,24659891,24531328,32557704,33520810,21865331,35178663,25372639,21894552,21538280,34798835,21245030,35327522,33198849,33892010,23274901,19637776,34174062,24081230,24890441,23394097,34511814,36515343,24966605,33652012,30834336,35411667,36557278,35434848,32921191,22933183,19267193,34211614,21332546,33640795,22373863,27794526,31826372,20945272,22160635,33808740,36233142,25297933,33039155,22927922,36340307,24632889,21898508,32143931,18565022,24719704,35083257,32172249,35769031,35397106,35914620,34746177,22465531,24563329,30415504,23292069,21694801,29242078,34529585,23390892,32853455,36305497,35338048,24010096,32552211,35897035,35474605,33088441,37118869,28754107,24635311,34949757,28316138,21302121,25246029,21533024,36686460,32836224,31290733,34692725,19729411,33986604,37103556,36984884,24371177,20879029,36580335,35607608,37088979,36735888,33817272,31781193,35154322,32603046,23063570,37105232,31388628,29201787,34171361,36950534,21970998,21944250,36324614,20920244,35511653,35211584,34430780,33239899,33964851,21674544,36591752,37029745,36705333,23341703,33376374,23113103,34455682,23980616,22153811,36065182,32812930,31290356,33705551,34007802,34581652,22710642,31606781,31650253,25920091,36630387,24357693,36719049[uid]

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Results by year

Year	Number of Results
2008	2
2009	6
2010	24
2011	36
2012	44
2013	43
2014	41
2015	31
2016	21
2017	19
2018	21
2019	28
2020	51
2021	83
2022	84
2023	27
2024	0

472 results

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Page 1

Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease.

Hotta K, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Chayama K, Nakajima A, Nakao K, Sekine A. Hotta K, et al. BMC Med Genet. 2010 Dec 22;11:172. doi: 10.1186/1471-2350-11-172. BMC Med Genet. 2010. PMID: 21176169 Free PMC article.

Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.

Kitamoto T, Kitamoto A, Yoneda M, Hyogo H, Ochi H, Nakamura T, Teranishi H, Mizusawa S, Ueno T, Chayama K, Nakajima A, Nakao K, Sekine A, Hotta K. Kitamoto T, et al. Hum Genet. 2013 Jul;132(7):783-92. doi: 10.1007/s00439-013-1294-3. Epub 2013 Mar 28. Hum Genet. 2013. PMID: 23535911 Free article. Clinical Trial.

Patatin-like phospholipase domain containing-3 gene I148M polymorphism, steatosis, and liver damage in hereditary hemochromatosis.

Valenti L, Maggioni P, Piperno A, Rametta R, Pelucchi S, Mariani R, Dongiovanni P, Fracanzani AL, Fargion S. Valenti L, et al. World J Gastroenterol. 2012 Jun 14;18(22):2813-20. doi: 10.3748/wjg.v18.i22.2813. World J Gastroenterol. 2012. PMID: 22719190 Free PMC article.

The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease.

Rotman Y, Koh C, Zmuda JM, Kleiner DE, Liang TJ; NASH CRN. Rotman Y, et al. Hepatology. 2010 Sep;52(3):894-903. doi: 10.1002/hep.23759. Hepatology. 2010. PMID: 20684021 Free PMC article.

I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease.

Valenti L, Alisi A, Galmozzi E, Bartuli A, Del Menico B, Alterio A, Dongiovanni P, Fargion S, Nobili V. Valenti L, et al. Hepatology. 2010 Oct;52(4):1274-80. doi: 10.1002/hep.23823. Hepatology. 2010. PMID: 20648474

Association between PNPLA3 rs738409 polymorphism and nonalcoholic fatty liver disease (NAFLD) susceptibility and severity: A meta-analysis.

Dai G, Liu P, Li X, Zhou X, He S. Dai G, et al. Medicine (Baltimore). 2019 Feb;98(7):e14324. doi: 10.1097/MD.0000000000014324. Medicine (Baltimore). 2019. PMID: 30762732 Free PMC article.

Patatin-like phospholipase domain-containing 3 I148M polymorphism, steatosis, and liver damage in chronic hepatitis C.

Valenti L, Rumi M, Galmozzi E, Aghemo A, Del Menico B, De Nicola S, Dongiovanni P, Maggioni M, Fracanzani AL, Rametta R, Colombo M, Fargion S. Valenti L, et al. Hepatology. 2011 Mar;53(3):791-9. doi: 10.1002/hep.24123. Epub 2011 Feb 11. Hepatology. 2011. PMID: 21319195

APOC3 rs2070666 Is Associated with the Hepatic Steatosis Independently of PNPLA3 rs738409 in Chinese Han Patients with Nonalcoholic Fatty Liver Diseases.

Zhang RN, Zheng RD, Mi YQ, Zhou D, Shen F, Chen GY, Zhu CY, Pan Q, Fan JG. Zhang RN, et al. Dig Dis Sci. 2016 Aug;61(8):2284-2293. doi: 10.1007/s10620-016-4120-7. Epub 2016 Apr 8. Dig Dis Sci. 2016. PMID: 27059980

No correlation between PNPLA3 rs738409 genotype and fatty liver and hepatic cirrhosis in Japanese patients with HCV.

Nakamura M, Kanda T, Nakamoto S, Miyamura T, Jiang X, Wu S, Yokosuka O. Nakamura M, et al. PLoS One. 2013 Dec 11;8(12):e81312. doi: 10.1371/journal.pone.0081312. eCollection 2013. PLoS One. 2013. PMID: 24349054 Free PMC article.

Patatin-like phospholipase domain-containing protein 3 rs738409-G in recipients of liver transplants is a risk factor for graft steatosis.

Finkenstedt A, Auer C, Glodny B, Posch U, Steitzer H, Lanzer G, Pratschke J, Biebl M, Steurer M, Graziadei I, Vogel W, Zoller H. Finkenstedt A, et al. Clin Gastroenterol Hepatol. 2013 Dec;11(12):1667-72. doi: 10.1016/j.cgh.2013.06.025. Epub 2013 Jul 18. Clin Gastroenterol Hepatol. 2013. PMID: 23872669

472 results

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