Similar articles for PMID: 22249354

Year	Number of Results
1980	1
1981	1
1982	1
1983	1
1984	1
1985	1
1989	5
1990	1
1992	1
1993	5
1994	5
1995	2
1998	2
2000	5
2001	2
2002	1
2003	2
2004	4
2005	5
2006	9
2007	4
2008	3
2009	3
2010	7
2011	7
2012	3
2013	6
2014	3
2015	7
2016	4
2017	12
2018	10
2019	7
2020	12
2021	6
2022	5
2023	2
2024	0

1

Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer.

Griffith M, Mwenifumbo JC, Cheung PY, Paul JE, Pugh TJ, Tang MJ, Chittaranjan S, Morin RD, Asano JK, Ally AA, Miao L, Lee A, Chan SY, Taylor G, Severson T, Hou YC, Griffith OL, Cheng GS, Novik K, Moore R, Luk M, Owen D, Brown CJ, Morin GB, Gill S, Tai IT, Marra MA. Griffith M, et al. Pharmacogenomics J. 2013 Apr;13(2):148-58. doi: 10.1038/tpj.2011.65. Epub 2012 Jan 17. Pharmacogenomics J. 2013. PMID: 22249354

2

LncRNA SNORD3A specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression.

Luo L, Zhang J, Tang H, Zhai D, Huang D, Ling L, Wang X, Liu T, Zhang Q, Zhang Z, He Z, Zheng G. Luo L, et al. Cell Death Dis. 2020 May 7;11(5):329. doi: 10.1038/s41419-020-2557-2. Cell Death Dis. 2020. PMID: 32382150 Free PMC article.

3

Functional analysis of pyrimidine biosynthesis enzymes using the anticancer drug 5-fluorouracil in Caenorhabditis elegans.

Kim S, Park DH, Kim TH, Hwang M, Shim J. Kim S, et al. FEBS J. 2009 Sep;276(17):4715-26. doi: 10.1111/j.1742-4658.2009.07168.x. Epub 2009 Jul 23. FEBS J. 2009. PMID: 19645718 Free article.

4

A Caenorhabditis elegans model of orotic aciduria reveals enlarged lysosome-related organelles in embryos lacking umps-1 function.

Levitte S, Salesky R, King B, Coe Smith S, Depper M, Cole M, Hermann GJ. Levitte S, et al. FEBS J. 2010 Mar;277(6):1420-39. doi: 10.1111/j.1742-4658.2010.07573.x. Epub 2010 Feb 10. FEBS J. 2010. PMID: 20148972 Free article.

5

Overexpression of the orotate phosphoribosyl-transferase gene enhances the effect of 5-fluorouracil on gastric cancer cell lines.

Taomoto J, Yoshida K, Wada Y, Tanabe K, Konishi K, Tahara H, Fukushima M. Taomoto J, et al. Oncology. 2006;70(6):458-64. doi: 10.1159/000098873. Epub 2007 Jan 19. Oncology. 2006. PMID: 17237621

6

Correlation between chemosensitivity and mRNA expression level of 5-fluorouracil-related metabolic enzymes during liver metastasis of colorectal cancer.

Okumura K, Shiomi H, Mekata E, Kaizuka M, Endo Y, Kurumi Y, Tani T. Okumura K, et al. Oncol Rep. 2006 Apr;15(4):875-82. Oncol Rep. 2006. PMID: 16525674

7

Synergistic effects of docetaxel and S-1 by modulating the expression of metabolic enzymes of 5-fluorouracil in human gastric cancer cell lines.

Wada Y, Yoshida K, Suzuki T, Mizuiri H, Konishi K, Ukon K, Tanabe K, Sakata Y, Fukushima M. Wada Y, et al. Int J Cancer. 2006 Aug 15;119(4):783-91. doi: 10.1002/ijc.21879. Int J Cancer. 2006. PMID: 16557585 Free article.

8

Inhibition of de novo pyrimidine synthesis in growing potato tubers leads to a compensatory stimulation of the pyrimidine salvage pathway and a subsequent increase in biosynthetic performance.

Geigenberger P, Regierer B, Nunes-Nesi A, Leisse A, Urbanczyk-Wochniak E, Springer F, van Dongen JT, Kossmann J, Fernie AR. Geigenberger P, et al. Plant Cell. 2005 Jul;17(7):2077-88. doi: 10.1105/tpc.105.033548. Epub 2005 Jun 10. Plant Cell. 2005. PMID: 15951490 Free PMC article.

9

Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy.

Ong HB, Sienkiewicz N, Wyllie S, Patterson S, Fairlamb AH. Ong HB, et al. Mol Microbiol. 2013 Oct;90(2):443-55. doi: 10.1111/mmi.12376. Epub 2013 Sep 9. Mol Microbiol. 2013. PMID: 23980694 Free PMC article.

10

Mild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences.

Wortmann SB, Chen MA, Colombo R, Pontoglio A, Alhaddad B, Botto LD, Yuzyuk T, Coughlin CR, Descartes M, Grűnewald S, Maranda B, Mills PB, Pitt J, Potente C, Rodenburg R, Kluijtmans LA, Sampath S, Pai EF, Wevers RA, Tiller GE; additional individual contributors. Wortmann SB, et al. J Inherit Metab Dis. 2017 May;40(3):423-431. doi: 10.1007/s10545-017-0015-9. Epub 2017 Feb 15. J Inherit Metab Dis. 2017. PMID: 28205048 Free PMC article.

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