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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2002 2
2003 1
2004 1
2005 3
2006 2
2007 1
2008 4
2009 6
2010 8
2011 16
2012 16
2013 27
2014 18
2015 10
2016 3
2017 4
2018 4
2019 8
2020 4
2021 0
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Similar articles for PMID: 22859857

119 results
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Page 1
Bardoxolone methyl decreases megalin and activates nrf2 in the kidney.
Reisman SA, Chertow GM, Hebbar S, Vaziri ND, Ward KW, Meyer CJ. Reisman SA, et al. J Am Soc Nephrol. 2012 Oct;23(10):1663-73. doi: 10.1681/ASN.2012050457. Epub 2012 Aug 2. J Am Soc Nephrol. 2012. PMID: 22859857 Free PMC article.
Bardoxolone methyl (BARD) ameliorates aristolochic acid (AA)-induced acute kidney injury through Nrf2 pathway.
Wu J, Liu X, Fan J, Chen W, Wang J, Zeng Y, Feng X, Yu X, Yang X. Wu J, et al. Toxicology. 2014 Apr 6;318:22-31. doi: 10.1016/j.tox.2014.01.008. Epub 2014 Feb 12. Toxicology. 2014. PMID: 24530882
A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas.
Hong DS, Kurzrock R, Supko JG, He X, Naing A, Wheler J, Lawrence D, Eder JP, Meyer CJ, Ferguson DA, Mier J, Konopleva M, Konoplev S, Andreeff M, Kufe D, Lazarus H, Shapiro GI, Dezube BJ. Hong DS, et al. Clin Cancer Res. 2012 Jun 15;18(12):3396-406. doi: 10.1158/1078-0432.CCR-11-2703. Epub 2012 May 25. Clin Cancer Res. 2012. PMID: 22634319 Free PMC article. Clinical Trial.
Effect of bardoxolone methyl on the urine albumin-to-creatinine ratio in patients with type 2 diabetes and stage 4 chronic kidney disease.
Rossing P, Block GA, Chin MP, Goldsberry A, Heerspink HJL, McCullough PA, Meyer CJ, Packham D, Pergola PE, Spinowitz B, Sprague SM, Warnock DG, Chertow GM. Rossing P, et al. Kidney Int. 2019 Oct;96(4):1030-1036. doi: 10.1016/j.kint.2019.04.027. Epub 2019 May 16. Kidney Int. 2019. PMID: 31377056 Clinical Trial.
The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores endothelial function impaired by reduced Nrf2 activity in chronic kidney disease.
Aminzadeh MA, Reisman SA, Vaziri ND, Shelkovnikov S, Farzaneh SH, Khazaeli M, Meyer CJ. Aminzadeh MA, et al. Redox Biol. 2013 Oct 31;1(1):527-31. doi: 10.1016/j.redox.2013.10.007. eCollection 2013. Redox Biol. 2013. PMID: 24363993 Free PMC article.
Bardoxolone methyl and kidney function in CKD with type 2 diabetes.
Pergola PE, Raskin P, Toto RD, Meyer CJ, Huff JW, Grossman EB, Krauth M, Ruiz S, Audhya P, Christ-Schmidt H, Wittes J, Warnock DG; BEAM Study Investigators. Pergola PE, et al. N Engl J Med. 2011 Jul 28;365(4):327-36. doi: 10.1056/NEJMoa1105351. Epub 2011 Jun 24. N Engl J Med. 2011. PMID: 21699484 Free article. Clinical Trial.
Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease.
de Zeeuw D, Akizawa T, Audhya P, Bakris GL, Chin M, Christ-Schmidt H, Goldsberry A, Houser M, Krauth M, Lambers Heerspink HJ, McMurray JJ, Meyer CJ, Parving HH, Remuzzi G, Toto RD, Vaziri ND, Wanner C, Wittes J, Wrolstad D, Chertow GM; BEACON Trial Investigators. de Zeeuw D, et al. N Engl J Med. 2013 Dec 26;369(26):2492-503. doi: 10.1056/NEJMoa1306033. Epub 2013 Nov 9. N Engl J Med. 2013. PMID: 24206459 Free PMC article. Clinical Trial.
Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease.
Ruiz S, Pergola PE, Zager RA, Vaziri ND. Ruiz S, et al. Kidney Int. 2013 Jun;83(6):1029-41. doi: 10.1038/ki.2012.439. Epub 2013 Jan 16. Kidney Int. 2013. PMID: 23325084 Free PMC article. Review.
Acute endotoxemia in mice induces downregulation of megalin and cubilin in the kidney.
Schreiber A, Theilig F, Schweda F, Höcherl K. Schreiber A, et al. Kidney Int. 2012 Jul;82(1):53-9. doi: 10.1038/ki.2012.62. Epub 2012 Mar 21. Kidney Int. 2012. PMID: 22437417 Free article.
Mechanisms contributing to adverse cardiovascular events in patients with type 2 diabetes mellitus and stage 4 chronic kidney disease treated with bardoxolone methyl.
Chin MP, Reisman SA, Bakris GL, O'Grady M, Linde PG, McCullough PA, Packham D, Vaziri ND, Ward KW, Warnock DG, Meyer CJ. Chin MP, et al. Am J Nephrol. 2014;39(6):499-508. doi: 10.1159/000362906. Epub 2014 Jun 3. Am J Nephrol. 2014. PMID: 24903467 Free article. Clinical Trial.
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