Similar articles for PMID: 24163244

Year	Number of Results
2006	2
2008	3
2009	5
2010	11
2011	11
2012	13
2013	10
2014	8
2015	7
2016	10
2017	18
2018	10
2019	6
2020	8
2021	12
2022	14
2023	8
2024	0

1

Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency.

Lee WC, Almeida S, Prudencio M, Caulfield TR, Zhang YJ, Tay WM, Bauer PO, Chew J, Sasaguri H, Jansen-West KR, Gendron TF, Stetler CT, Finch N, Mackenzie IR, Rademakers R, Gao FB, Petrucelli L. Lee WC, et al. Hum Mol Genet. 2014 Mar 15;23(6):1467-78. doi: 10.1093/hmg/ddt534. Epub 2013 Oct 26. Hum Mol Genet. 2014. PMID: 24163244 Free PMC article.

2

Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.

Hu F, Padukkavidana T, Vægter CB, Brady OA, Zheng Y, Mackenzie IR, Feldman HH, Nykjaer A, Strittmatter SM. Hu F, et al. Neuron. 2010 Nov 18;68(4):654-67. doi: 10.1016/j.neuron.2010.09.034. Neuron. 2010. PMID: 21092856 Free PMC article.

3

Progranulin regulates neuronal outgrowth independent of sortilin.

Gass J, Lee WC, Cook C, Finch N, Stetler C, Jansen-West K, Lewis J, Link CD, Rademakers R, Nykjær A, Petrucelli L. Gass J, et al. Mol Neurodegener. 2012 Jul 10;7:33. doi: 10.1186/1750-1326-7-33. Mol Neurodegener. 2012. PMID: 22781549 Free PMC article.

4

The neurotrophic properties of progranulin depend on the granulin E domain but do not require sortilin binding.

De Muynck L, Herdewyn S, Beel S, Scheveneels W, Van Den Bosch L, Robberecht W, Van Damme P. De Muynck L, et al. Neurobiol Aging. 2013 Nov;34(11):2541-7. doi: 10.1016/j.neurobiolaging.2013.04.022. Epub 2013 May 24. Neurobiol Aging. 2013. PMID: 23706646

5

Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRN Mutations.

Holler CJ, Taylor G, Deng Q, Kukar T. Holler CJ, et al. eNeuro. 2017 Aug 18;4(4):ENEURO.0100-17.2017. doi: 10.1523/ENEURO.0100-17.2017. eCollection 2017 Jul-Aug. eNeuro. 2017. PMID: 28828399 Free PMC article.

6

Progranulin-mediated deficiency of cathepsin D results in FTD and NCL-like phenotypes in neurons derived from FTD patients.

Valdez C, Wong YC, Schwake M, Bu G, Wszolek ZK, Krainc D. Valdez C, et al. Hum Mol Genet. 2017 Dec 15;26(24):4861-4872. doi: 10.1093/hmg/ddx364. Hum Mol Genet. 2017. PMID: 29036611 Free PMC article.

7

Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers.

Alquézar C, de la Encarnación A, Moreno F, López de Munain A, Martín-Requero Á. Alquézar C, et al. J Psychiatry Neurosci. 2016 Jun;41(4):225-39. doi: 10.1503/jpn.150131. J Psychiatry Neurosci. 2016. PMID: 26624524 Free PMC article.

8

Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia.

Raitano S, Ordovàs L, De Muynck L, Guo W, Espuny-Camacho I, Geraerts M, Khurana S, Vanuytsel K, Tóth BI, Voets T, Vandenberghe R, Cathomen T, Van Den Bosch L, Vanderhaeghen P, Van Damme P, Verfaillie CM. Raitano S, et al. Stem Cell Reports. 2015 Jan 13;4(1):16-24. doi: 10.1016/j.stemcr.2014.12.001. Epub 2014 Dec 31. Stem Cell Reports. 2015. PMID: 25556567 Free PMC article.

9

Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia.

Holler CJ, Taylor G, McEachin ZT, Deng Q, Watkins WJ, Hudson K, Easley CA, Hu WT, Hales CM, Rossoll W, Bassell GJ, Kukar T. Holler CJ, et al. Mol Neurodegener. 2016 Jun 24;11(1):46. doi: 10.1186/s13024-016-0114-3. Mol Neurodegener. 2016. PMID: 27341800 Free PMC article.

10

Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects.

Almeida S, Zhang Z, Coppola G, Mao W, Futai K, Karydas A, Geschwind MD, Tartaglia MC, Gao F, Gianni D, Sena-Esteves M, Geschwind DH, Miller BL, Farese RV Jr, Gao FB. Almeida S, et al. Cell Rep. 2012 Oct 25;2(4):789-98. doi: 10.1016/j.celrep.2012.09.007. Epub 2012 Oct 11. Cell Rep. 2012. PMID: 23063362 Free PMC article.

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