Similar articles for PMID: 26628643

Year	Number of Results
2012	1
2013	7
2014	14
2015	12
2016	15
2017	23
2018	12
2019	10
2020	6
2021	7
2022	2
2023	1
2024	0

1

Rationally engineered Cas9 nucleases with improved specificity.

Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. Slaymaker IM, et al. Science. 2016 Jan 1;351(6268):84-8. doi: 10.1126/science.aad5227. Epub 2015 Dec 1. Science. 2016. PMID: 26628643 Free PMC article.

2

Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9.

Hirano S, Nishimasu H, Ishitani R, Nureki O. Hirano S, et al. Mol Cell. 2016 Mar 17;61(6):886-94. doi: 10.1016/j.molcel.2016.02.018. Mol Cell. 2016. PMID: 26990991 Free article.

3

Engineered CRISPR-Cas9 nucleases with altered PAM specificities.

Kleinstiver BP, Prew MS, Tsai SQ, Topkar VV, Nguyen NT, Zheng Z, Gonzales AP, Li Z, Peterson RT, Yeh JR, Aryee MJ, Joung JK. Kleinstiver BP, et al. Nature. 2015 Jul 23;523(7561):481-5. doi: 10.1038/nature14592. Epub 2015 Jun 22. Nature. 2015. PMID: 26098369 Free PMC article.

4

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

Cho SW, Kim S, Kim Y, Kweon J, Kim HS, Bae S, Kim JS. Cho SW, et al. Genome Res. 2014 Jan;24(1):132-41. doi: 10.1101/gr.162339.113. Epub 2013 Nov 19. Genome Res. 2014. PMID: 24253446 Free PMC article.

5

Engineered CRISPR-Cas9 nuclease with expanded targeting space.

Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, Aburatani H, Ishitani R, Ikawa M, Yachie N, Zhang F, Nureki O. Nishimasu H, et al. Science. 2018 Sep 21;361(6408):1259-1262. doi: 10.1126/science.aas9129. Epub 2018 Aug 30. Science. 2018. PMID: 30166441 Free PMC article.

6

Developing Heritable Mutations in Arabidopsis thaliana Using a Modified CRISPR/Cas9 Toolkit Comprising PAM-Altered Cas9 Variants and gRNAs.

Yamamoto A, Ishida T, Yoshimura M, Kimura Y, Sawa S. Yamamoto A, et al. Plant Cell Physiol. 2019 Oct 1;60(10):2255-2262. doi: 10.1093/pcp/pcz118. Plant Cell Physiol. 2019. PMID: 31198958

7

Probing the structural dynamics of the CRISPR-Cas9 RNA-guided DNA-cleavage system by coarse-grained modeling.

Zheng W. Zheng W. Proteins. 2017 Feb;85(2):342-353. doi: 10.1002/prot.25229. Epub 2017 Jan 5. Proteins. 2017. PMID: 27936513

8

Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.

Chen JS, Dagdas YS, Kleinstiver BP, Welch MM, Sousa AA, Harrington LB, Sternberg SH, Joung JK, Yildiz A, Doudna JA. Chen JS, et al. Nature. 2017 Oct 19;550(7676):407-410. doi: 10.1038/nature24268. Epub 2017 Sep 20. Nature. 2017. PMID: 28931002 Free PMC article.

9

Crossing enhanced and high fidelity SpCas9 nucleases to optimize specificity and cleavage.

Kulcsár PI, Tálas A, Huszár K, Ligeti Z, Tóth E, Weinhardt N, Fodor E, Welker E. Kulcsár PI, et al. Genome Biol. 2017 Oct 6;18(1):190. doi: 10.1186/s13059-017-1318-8. Genome Biol. 2017. PMID: 28985763 Free PMC article.

10

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

Kleinstiver BP, Pattanayak V, Prew MS, Tsai SQ, Nguyen NT, Zheng Z, Joung JK. Kleinstiver BP, et al. Nature. 2016 Jan 28;529(7587):490-5. doi: 10.1038/nature16526. Epub 2016 Jan 6. Nature. 2016. PMID: 26735016 Free PMC article.

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