Similar articles for PMID: 26673892

Year	Number of Results
1999	1
2000	1
2001	2
2002	1
2004	3
2005	1
2006	3
2007	2
2008	1
2009	1
2010	2
2011	1
2013	3
2014	6
2015	10
2016	7
2017	2
2018	5
2019	3
2020	3
2021	2
2022	7
2023	4
2024	0

1

Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes.

Lasagna-Reeves CA, Rousseaux MW, Guerrero-Munoz MJ, Vilanova-Velez L, Park J, See L, Jafar-Nejad P, Richman R, Orr HT, Kayed R, Zoghbi HY. Lasagna-Reeves CA, et al. Elife. 2015 Dec 17;4:e10891. doi: 10.7554/eLife.10891. Elife. 2015. PMID: 26673892 Free PMC article.

2

A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1.

Lasagna-Reeves CA, Rousseaux MW, Guerrero-Muñoz MJ, Park J, Jafar-Nejad P, Richman R, Lu N, Sengupta U, Litvinchuk A, Orr HT, Kayed R, Zoghbi HY. Lasagna-Reeves CA, et al. Elife. 2015 May 19;4:e07558. doi: 10.7554/eLife.07558. Elife. 2015. PMID: 25988806 Free PMC article.

3

Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.

Shuvaev AN, Belozor OS, Mozhei OI, Shuvaev AN, Fritsler YV, Khilazheva ED, Mosyagina AI, Hirai H, Teschemacher AG, Kasparov S. Shuvaev AN, et al. Cells. 2022 Jul 20;11(14):2247. doi: 10.3390/cells11142247. Cells. 2022. PMID: 35883691 Free PMC article.

4

PAK1 regulates ATXN1 levels providing an opportunity to modify its toxicity in spinocerebellar ataxia type 1.

Bondar VV, Adamski CJ, Onur TS, Tan Q, Wang L, Diaz-Garcia J, Park J, Orr HT, Botas J, Zoghbi HY. Bondar VV, et al. Hum Mol Genet. 2018 Aug 15;27(16):2863-2873. doi: 10.1093/hmg/ddy200. Hum Mol Genet. 2018. PMID: 29860311 Free PMC article.

5

Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model.

Watase K, Gatchel JR, Sun Y, Emamian E, Atkinson R, Richman R, Mizusawa H, Orr HT, Shaw C, Zoghbi HY. Watase K, et al. PLoS Med. 2007 May;4(5):e182. doi: 10.1371/journal.pmed.0040182. PLoS Med. 2007. PMID: 17535104 Free PMC article.

6

Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1).

Sánchez I, Balagué E, Matilla-Dueñas A. Sánchez I, et al. Hum Mol Genet. 2016 Sep 15;25(18):4021-4040. doi: 10.1093/hmg/ddw242. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466200

7

Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1.

Nitschke L, Coffin SL, Xhako E, El-Najjar DB, Orengo JP, Alcala E, Dai Y, Wan YW, Liu Z, Orr HT, Zoghbi HY. Nitschke L, et al. JCI Insight. 2021 Feb 8;6(3):e144955. doi: 10.1172/jci.insight.144955. JCI Insight. 2021. PMID: 33554954 Free PMC article.

8

RNAi prevents and reverses phenotypes induced by mutant human ataxin-1.

Keiser MS, Monteys AM, Corbau R, Gonzalez-Alegre P, Davidson BL. Keiser MS, et al. Ann Neurol. 2016 Nov;80(5):754-765. doi: 10.1002/ana.24789. Epub 2016 Nov 2. Ann Neurol. 2016. PMID: 27686464 Free PMC article.

9

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.

Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajić A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT. Rousseaux MWC, et al. Neuron. 2018 Mar 21;97(6):1235-1243.e5. doi: 10.1016/j.neuron.2018.02.013. Epub 2018 Mar 8. Neuron. 2018. PMID: 29526553 Free PMC article.

10

Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes.

Bowman AB, Lam YC, Jafar-Nejad P, Chen HK, Richman R, Samaco RC, Fryer JD, Kahle JJ, Orr HT, Zoghbi HY. Bowman AB, et al. Nat Genet. 2007 Mar;39(3):373-9. doi: 10.1038/ng1977. Epub 2007 Feb 18. Nat Genet. 2007. PMID: 17322884

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