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Results by year

Year	Number of Results
2009	1
2010	2
2011	9
2012	10
2013	17
2014	42
2015	64
2016	79
2017	95
2018	86
2019	90
2020	84
2021	75
2022	49
2023	26
2024	0

614 results

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Page 1

Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome.

Greenbaum LA, Fila M, Ardissino G, Al-Akash SI, Evans J, Henning P, Lieberman KV, Maringhini S, Pape L, Rees L, van de Kar NC, Vande Walle J, Ogawa M, Bedrosian CL, Licht C. Greenbaum LA, et al. Kidney Int. 2016 Mar;89(3):701-11. doi: 10.1016/j.kint.2015.11.026. Epub 2016 Jan 28. Kidney Int. 2016. PMID: 26880462 Free article. Clinical Trial.

Terminal Complement Inhibitor Eculizumab in Adult Patients With Atypical Hemolytic Uremic Syndrome: A Single-Arm, Open-Label Trial.

Fakhouri F, Hourmant M, Campistol JM, Cataland SR, Espinosa M, Gaber AO, Menne J, Minetti EE, Provôt F, Rondeau E, Ruggenenti P, Weekers LE, Ogawa M, Bedrosian CL, Legendre CM. Fakhouri F, et al. Am J Kidney Dis. 2016 Jul;68(1):84-93. doi: 10.1053/j.ajkd.2015.12.034. Epub 2016 Mar 21. Am J Kidney Dis. 2016. PMID: 27012908 Free article. Clinical Trial.

Safety and effectiveness of eculizumab for pediatric patients with atypical hemolytic-uremic syndrome in Japan: interim analysis of post-marketing surveillance.

Ito S, Hidaka Y, Inoue N, Kaname S, Kato H, Matsumoto M, Miyakawa Y, Mizuno M, Okada H, Shimono A, Matsuda T, Maruyama S, Fujimura Y, Nangaku M, Kagami S. Ito S, et al. Clin Exp Nephrol. 2019 Jan;23(1):112-121. doi: 10.1007/s10157-018-1610-2. Epub 2018 Jul 23. Clin Exp Nephrol. 2019. PMID: 30039480 Free PMC article.

Outcomes in patients with atypical hemolytic uremic syndrome treated with eculizumab in a long-term observational study.

Menne J, Delmas Y, Fakhouri F, Licht C, Lommelé Å, Minetti EE, Provôt F, Rondeau E, Sheerin NS, Wang J, Weekers LE, Greenbaum LA. Menne J, et al. BMC Nephrol. 2019 Apr 10;20(1):125. doi: 10.1186/s12882-019-1314-1. BMC Nephrol. 2019. PMID: 30971227 Free PMC article.

Efficacy and safety of the long-acting C5 inhibitor ravulizumab in patients with atypical hemolytic uremic syndrome triggered by pregnancy: a subgroup analysis.

Gäckler A, Schönermarck U, Dobronravov V, La Manna G, Denker A, Liu P, Vinogradova M, Yoon SS, Praga M. Gäckler A, et al. BMC Nephrol. 2021 Jan 6;22(1):5. doi: 10.1186/s12882-020-02190-0. BMC Nephrol. 2021. PMID: 33407224 Free PMC article. Clinical Trial.

Safety and effectiveness of eculizumab for adult patients with atypical hemolytic-uremic syndrome in Japan: interim analysis of post-marketing surveillance.

Kato H, Miyakawa Y, Hidaka Y, Inoue N, Ito S, Kagami S, Kaname S, Matsumoto M, Mizuno M, Matsuda T, Shimono A, Maruyama S, Fujimura Y, Nangaku M, Okada H. Kato H, et al. Clin Exp Nephrol. 2019 Jan;23(1):65-75. doi: 10.1007/s10157-018-1609-8. Epub 2018 Jun 29. Clin Exp Nephrol. 2019. PMID: 29959568 Free PMC article.

Atypical hemolytic uremic syndrome in the setting of complement-amplifying conditions: case reports and a review of the evidence for treatment with eculizumab.

Asif A, Nayer A, Haas CS. Asif A, et al. J Nephrol. 2017 Jun;30(3):347-362. doi: 10.1007/s40620-016-0357-7. Epub 2016 Nov 15. J Nephrol. 2017. PMID: 27848226 Free PMC article. Review.

Atypical haemolytic uraemic syndrome treated with the complement inhibitor eculizumab: the experience of the Australian compassionate access cohort.

Mallett A, Hughes P, Szer J, Tuckfield A, Van Eps C, Cambell SB, Hawley C, Burke J, Kausman J, Hewitt I, Parnham A, Ford S, Isbel N. Mallett A, et al. Intern Med J. 2015 Oct;45(10):1054-65. doi: 10.1111/imj.12864. Intern Med J. 2015. PMID: 26247170

Efficacy and safety of eculizumab in adult patients with atypical hemolytic uremic syndrome: A single center experience from Turkey.

Gediz F, Payzin BK, Ecemis S, Güler N, Yilmaz AF, Topcugil F, Berdeli A. Gediz F, et al. Transfus Apher Sci. 2016 Dec;55(3):357-362. doi: 10.1016/j.transci.2016.09.017. Epub 2016 Sep 30. Transfus Apher Sci. 2016. PMID: 27742267

Efficacy and safety of eculizumab in childhood atypical hemolytic uremic syndrome in Japan.

Ito N, Hataya H, Saida K, Amano Y, Hidaka Y, Motoyoshi Y, Ohta T, Yoshida Y, Terano C, Iwasa T, Kubota W, Takada H, Hara T, Fujimura Y, Ito S. Ito N, et al. Clin Exp Nephrol. 2016 Apr;20(2):265-72. doi: 10.1007/s10157-015-1142-y. Epub 2015 Jul 9. Clin Exp Nephrol. 2016. PMID: 26156042

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