Similar articles for PMID: 27889231

Year	Number of Results
1996	1
1997	1
2000	1
2001	3
2003	1
2005	3
2006	6
2007	6
2008	3
2009	4
2010	6
2011	6
2012	9
2013	5
2014	10
2015	8
2016	15
2017	22
2018	13
2019	10
2020	4
2021	13
2022	11
2023	9
2024	9
2025	1

1

Nimbolide inhibits androgen independent prostate cancer cells survival and proliferation by modulating multiple pro-survival signaling pathways.

Singh PR, Priya ES, Balakrishnan S, Arunkumar R, Sharmila G, Rajalakshmi M, Arunakaran J. Singh PR, et al. Biomed Pharmacother. 2016 Dec;84:1623-1634. doi: 10.1016/j.biopha.2016.10.076. Epub 2016 Nov 23. Biomed Pharmacother. 2016. PMID: 27889231

2

Inhibition of cell survival and proliferation by nimbolide in human androgen-independent prostate cancer (PC-3) cells: involvement of the PI3K/Akt pathway.

Raja Singh P, Sugantha Priya E, Balakrishnan S, Arunkumar R, Sharmila G, Rajalakshmi M, Arunakaran J. Raja Singh P, et al. Mol Cell Biochem. 2017 Mar;427(1-2):69-79. doi: 10.1007/s11010-016-2898-4. Epub 2016 Dec 26. Mol Cell Biochem. 2017. PMID: 28025797

3

Anti-proliferative and apoptosis inducing effect of nimbolide by altering molecules involved in apoptosis and IGF signalling via PI3K/Akt in prostate cancer (PC-3) cell line.

Raja Singh P, Arunkumar R, Sivakamasundari V, Sharmila G, Elumalai P, Suganthapriya E, Brindha Mercy A, Senthilkumar K, Arunakaran J. Raja Singh P, et al. Cell Biochem Funct. 2014 Apr;32(3):217-28. doi: 10.1002/cbf.2993. Epub 2013 Aug 21. Cell Biochem Funct. 2014. PMID: 23963693

4

Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP-2/9 expression via inhibiting ERK1/2 and reducing DNA-binding activity of NF-κB in colon cancer cells.

Babykutty S, S PP, J NR, Kumar MA, Nair MS, Srinivas P, Gopala S. Babykutty S, et al. Mol Carcinog. 2012 Jun;51(6):475-90. doi: 10.1002/mc.20812. Epub 2011 Jun 15. Mol Carcinog. 2012. PMID: 21678498

5

Combination of Nimbolide and TNF-α-Increases Human Colon Adenocarcinoma Cell Death through JNK-mediated DR5 Up- regulation.

Chantana C, Yenjai C, Reubroycharoen P, Waiwut P. Chantana C, et al. Asian Pac J Cancer Prev. 2016;17(5):2637-41. Asian Pac J Cancer Prev. 2016. PMID: 27268643 Free article.

6

Modification of cysteine 179 of IkappaBalpha kinase by nimbolide leads to down-regulation of NF-kappaB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents.

Gupta SC, Prasad S, Reuter S, Kannappan R, Yadav VR, Ravindran J, Hema PS, Chaturvedi MM, Nair M, Aggarwal BB. Gupta SC, et al. J Biol Chem. 2010 Nov 12;285(46):35406-17. doi: 10.1074/jbc.M110.161984. Epub 2010 Sep 9. J Biol Chem. 2010. PMID: 20829362 Free PMC article.

7

Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation.

Pooladanda V, Thatikonda S, Bale S, Pattnaik B, Sigalapalli DK, Bathini NB, Singh SB, Godugu C. Pooladanda V, et al. Cell Death Dis. 2019 Jan 28;10(2):81. doi: 10.1038/s41419-018-1247-9. Cell Death Dis. 2019. PMID: 30692512 Free PMC article.

8

Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB.

Kasof GM, Lu JJ, Liu D, Speer B, Mongan KN, Gomes BC, Lorenzi MV. Kasof GM, et al. Oncogene. 2001 Nov 29;20(55):7965-75. doi: 10.1038/sj.onc.1204985. Oncogene. 2001. PMID: 11753679

9

Nimbolide, a limonoid triterpene, inhibits growth of human colorectal cancer xenografts by suppressing the proinflammatory microenvironment.

Gupta SC, Prasad S, Sethumadhavan DR, Nair MS, Mo YY, Aggarwal BB. Gupta SC, et al. Clin Cancer Res. 2013 Aug 15;19(16):4465-76. doi: 10.1158/1078-0432.CCR-13-0080. Epub 2013 Jun 13. Clin Cancer Res. 2013. PMID: 23766363 Free PMC article.

10

TNF alpha acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-kappa B-dependent pathways.

Rivas MA, Carnevale RP, Proietti CJ, Rosemblit C, Beguelin W, Salatino M, Charreau EH, Frahm I, Sapia S, Brouckaert P, Elizalde PV, Schillaci R. Rivas MA, et al. Exp Cell Res. 2008 Feb 1;314(3):509-29. doi: 10.1016/j.yexcr.2007.10.005. Epub 2007 Oct 13. Exp Cell Res. 2008. PMID: 18061162

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