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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
2001 1
2002 1
2003 4
2004 5
2005 7
2006 4
2007 7
2008 8
2009 7
2010 11
2011 10
2012 7
2013 11
2014 10
2015 4
2016 8
2017 8
2018 2
2019 1
2020 2
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Similar Articles for PMID: 28167741

102 results
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A New Molecular Mechanism To Engineer Protean Agonism at a G Protein-Coupled Receptor.
De Min A, Matera C, Bock A, Holze J, Kloeckner J, Muth M, Traenkle C, De Amici M, Kenakin T, Holzgrabe U, Dallanoce C, Kostenis E, Mohr K, Schrage R. De Min A, et al. Mol Pharmacol. 2017 Apr;91(4):348-356. doi: 10.1124/mol.116.107276. Epub 2017 Feb 6. Mol Pharmacol. 2017. PMID: 28167741
Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor.
Bock A, Bermudez M, Krebs F, Matera C, Chirinda B, Sydow D, Dallanoce C, Holzgrabe U, De Amici M, Lohse MJ, Wolber G, Mohr K. Bock A, et al. J Biol Chem. 2016 Jul 29;291(31):16375-89. doi: 10.1074/jbc.M116.735431. Epub 2016 Jun 13. J Biol Chem. 2016. PMID: 27298318 Free PMC article.
Engineered Context-Sensitive Agonism: Tissue-Selective Drug Signaling through a G Protein-Coupled Receptor.
Seemann WK, Wenzel D, Schrage R, Etscheid J, Bödefeld T, Bartol A, Warnken M, Sasse P, Klöckner J, Holzgrabe U, DeAmici M, Schlicker E, Racké K, Kostenis E, Meyer R, Fleischmann BK, Mohr K. Seemann WK, et al. J Pharmacol Exp Ther. 2017 Feb;360(2):289-299. doi: 10.1124/jpet.116.237149. Epub 2016 Nov 15. J Pharmacol Exp Ther. 2017. PMID: 28082514
Allosteric modulation in monomers and oligomers of a G protein-coupled receptor.
Shivnaraine RV, Kelly B, Sankar KS, Redka DS, Han YR, Huang F, Elmslie G, Pinto D, Li Y, Rocheleau JV, Gradinaru CC, Ellis J, Wells JW. Shivnaraine RV, et al. Elife. 2016 May 6;5:e11685. doi: 10.7554/eLife.11685. Elife. 2016. PMID: 27151542 Free PMC article.
Rational design of dualsteric GPCR ligands: quests and promise.
Mohr K, Tränkle C, Kostenis E, Barocelli E, De Amici M, Holzgrabe U. Mohr K, et al. Br J Pharmacol. 2010 Mar;159(5):997-1008. doi: 10.1111/j.1476-5381.2009.00601.x. Epub 2010 Feb 5. Br J Pharmacol. 2010. PMID: 20136835 Free PMC article. Review.
Allosteric small molecules unveil a role of an extracellular E2/transmembrane helix 7 junction for G protein-coupled receptor activation.
Jäger D, Schmalenbach C, Prilla S, Schrobang J, Kebig A, Sennwitz M, Heller E, Tränkle C, Holzgrabe U, Höltje HD, Mohr K. Jäger D, et al. J Biol Chem. 2007 Nov 30;282(48):34968-76. doi: 10.1074/jbc.M705563200. Epub 2007 Sep 21. J Biol Chem. 2007. PMID: 17890226 Free article.
New insight into active muscarinic receptors with the novel radioagonist [³H]iperoxo.
Schrage R, Holze J, Klöckner J, Balkow A, Klause AS, Schmitz AL, De Amici M, Kostenis E, Tränkle C, Holzgrabe U, Mohr K. Schrage R, et al. Biochem Pharmacol. 2014 Aug 1;90(3):307-19. doi: 10.1016/j.bcp.2014.05.012. Epub 2014 May 23. Biochem Pharmacol. 2014. PMID: 24863257
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