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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1995 1
1999 1
2001 2
2003 1
2004 1
2005 3
2008 1
2009 1
2010 2
2011 5
2012 5
2013 12
2014 4
2015 8
2016 13
2017 15
2018 12
2019 4
2020 6
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Page 1
The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.
Greene LM, Nathwani SM, Bright SA, Fayne D, Croke A, Gagliardi M, McElligott AM, O'Connor L, Carr M, Keely NO, O'Boyle NM, Carroll P, Sarkadi B, Conneally E, Lloyd DG, Lawler M, Meegan MJ, Zisterer DM. Greene LM, et al. J Pharmacol Exp Ther. 2010 Nov;335(2):302-13. doi: 10.1124/jpet.110.170415. Epub 2010 Aug 10. J Pharmacol Exp Ther. 2010. PMID: 20699436
Docking, synthesis and antiproliferative activity of N-acylhydrazone derivatives designed as combretastatin A4 analogues.
do Amaral DN, Cavalcanti BC, Bezerra DP, Ferreira PM, Castro Rde P, Sabino JR, Machado CM, Chammas R, Pessoa C, Sant'Anna CM, Barreiro EJ, Lima LM. do Amaral DN, et al. PLoS One. 2014 Mar 10;9(3):e85380. doi: 10.1371/journal.pone.0085380. eCollection 2014. PLoS One. 2014. PMID: 24614859 Free PMC article.
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral Ī²-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y. Zhou P, et al. Eur J Med Chem. 2018 Jan 20;144:817-842. doi: 10.1016/j.ejmech.2017.12.004. Epub 2017 Dec 7. Eur J Med Chem. 2018. PMID: 29306206
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