Similar articles for PMID: 30178575

Year	Number of Results
1990	1
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1999	2
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1

Design and Synthesis of Bioisosteres of Acylhydrazones as Stable Inhibitors of the Aspartic Protease Endothiapepsin.

Jumde VR, Mondal M, Gierse RM, Unver MY, Magari F, van Lier RCW, Heine A, Klebe G, Hirsch AKH. Jumde VR, et al. ChemMedChem. 2018 Nov 6;13(21):2266-2270. doi: 10.1002/cmdc.201800446. Epub 2018 Oct 9. ChemMedChem. 2018. PMID: 30178575 Free PMC article.

2

Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin: Fragment-Based Drug Design Facilitated by Dynamic Combinatorial Chemistry.

Mondal M, Radeva N, Fanlo-Virgós H, Otto S, Klebe G, Hirsch AK. Mondal M, et al. Angew Chem Int Ed Engl. 2016 Aug 1;55(32):9422-6. doi: 10.1002/anie.201603074. Epub 2016 Jul 12. Angew Chem Int Ed Engl. 2016. PMID: 27400756 Free PMC article.

3

Structure-Based Optimization of Inhibitors of the Aspartic Protease Endothiapepsin.

Hartman AM, Mondal M, Radeva N, Klebe G, Hirsch AK. Hartman AM, et al. Int J Mol Sci. 2015 Aug 14;16(8):19184-94. doi: 10.3390/ijms160819184. Int J Mol Sci. 2015. PMID: 26287174 Free PMC article.

4

Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry.

Mondal M, Radeva N, Köster H, Park A, Potamitis C, Zervou M, Klebe G, Hirsch AK. Mondal M, et al. Angew Chem Int Ed Engl. 2014 Mar 17;53(12):3259-63. doi: 10.1002/anie.201309682. Epub 2014 Feb 14. Angew Chem Int Ed Engl. 2014. PMID: 24532096

5

The structure of endothiapepsin complexed with a Phe-Tyr reduced-bond inhibitor at 1.35 Å resolution.

Guo J, Cooper JB, Wood SP. Guo J, et al. Acta Crystallogr F Struct Biol Commun. 2014 Jan;70(Pt 1):30-3. doi: 10.1107/S2053230X13032974. Epub 2013 Dec 24. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 24419612 Free PMC article.

6

Fragment-Based Drug Design Facilitated by Protein-Templated Click Chemistry: Fragment Linking and Optimization of Inhibitors of the Aspartic Protease Endothiapepsin.

Mondal M, Unver MY, Pal A, Bakker M, Berrier SP, Hirsch AK. Mondal M, et al. Chemistry. 2016 Oct 10;22(42):14826-14830. doi: 10.1002/chem.201603001. Epub 2016 Sep 7. Chemistry. 2016. PMID: 27604032 Free PMC article.

7

Tracing binding modes in hit-to-lead optimization: chameleon-like poses of aspartic protease inhibitors.

Kuhnert M, Köster H, Bartholomäus R, Park AY, Shahim A, Heine A, Steuber H, Klebe G, Diederich WE. Kuhnert M, et al. Angew Chem Int Ed Engl. 2015 Feb 23;54(9):2849-53. doi: 10.1002/anie.201411206. Epub 2015 Jan 28. Angew Chem Int Ed Engl. 2015. PMID: 25630461

8

An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases.

Bailey D, Carpenter EP, Coker A, Coker S, Read J, Jones AT, Erskine P, Aguilar CF, Badasso M, Toldo L, Rippmann F, Sanz-Aparicio J, Albert A, Blundell TL, Roberts NB, Wood SP, Cooper JB. Bailey D, et al. Acta Crystallogr D Biol Crystallogr. 2012 May;68(Pt 5):541-52. doi: 10.1107/S0907444912004817. Epub 2012 Apr 17. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22525752 Free article.

9

Non-invasive ¹⁹F NMR analysis of a protein-templated N-acylhydrazone dynamic combinatorial library.

Ekström AG, Wang JT, Bella J, Campopiano DJ. Ekström AG, et al. Org Biomol Chem. 2018 Nov 7;16(43):8144-8149. doi: 10.1039/c8ob01918e. Org Biomol Chem. 2018. PMID: 30334559

10

Aspartic protease inhibitors designed from computer-generated templates bind as predicted.

Ripka AS, Satyshur KA, Bohacek RS, Rich DH. Ripka AS, et al. Org Lett. 2001 Jul 26;3(15):2309-12. doi: 10.1021/ol016090+. Org Lett. 2001. PMID: 11463303

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