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26411297,38605715,38409199,38405743,38390187,38385549,38362491,38328240,38319094,38312197,38291757,38274248,38262608,38257946,38257926,38249803,38242128,38239344,38235361,38222286,38173969,38145986,38126782,38099659,38089835,38076202,38069429,38053290,38033324,38027068,38009957,37914776,37908767,37892243,37892067,37878144,37875603,37873636,37869712,37849926,37848032,37808520,37799600,37764119,37723612,37711183,37692518,37691844,37684555,37662134,37636024,37628594,37583709,37526970,37522927,37510242,37502928,37500801,37483353,37460924,37426982,37396453,37396379,37375454,37370394,37359078,37352230,37347159,37346997,37326009,37305433,37296137,37289828,37283088,37269466,37239967,37210555,37192099,37191877,37185566,37158910,37107608,37098485,37090614,37073287,37069118,37052300,37047235,36993599,36983530,36926973,36925473,36919203,36913066,36912817,36901793,36895064,36851733,36843655,36841874,36831926,36830769,36830292,36826021,36823453,36818498,36811465,36807980,36805026,36801863,36797756,36790185,36787424,36727449,36710911,36707422,36702942,36698226,36690762,36687047,36675099,36672870,36638909,36631688,36571299,36569102,36558949,36532491,36508352,36483767,36479105,36474907,36460704,36443433,36429003,36419420,36404524,36379609,36374018,36370236,36361556,36338063,36305833,36305005,36296588,36292145,36290480,36272994,36268581,36264297,36255694,36246261,36233352,36232699,36209487,36207756,36199433,36197590,36185462,36178514,36175516,36172044,36163386,36162812,36158212,36145721,36127328,36109551,36107767,36107373,36100322,36082000,36080431,36078073,36073935,36060733,36044181,36029350,36016778,36014162,36008567,35966677,35959889,35958050,35955649,35942309,35942232,35935840,35920322,35920132,35918353,35891620,35884169,35880867,35879798,35857175,35854181,35852729,35845351,35836569,35822842,35797344,35796760,35786440,35760837,35752612,35751791,35741761,35741144,35722296,35721864,35714601,35692726,35690065,35680848,35674844,35643959,35642647,35628723,35628210,35595728,35585381,35572153,35568789,35548117,35502187,35495695,35475644,35457271,35445018,35402511,35396392,35390680,35388097,35386853,35356276,35351985,35349718,35340361,35337340,35308851,35258601,35251748,35250944,35250902,35246186,35232910,35222299,35211539,35208706,35200314,35185818,35184547,35166843,35163678,35143386,35129865,35087864,35069497,35068602,35062978,35051351,35038453,35022246,34986140,34975291,34973111,34956138,34954876,34954815,34953139,34947888,34903162,34901007,34871408,34863214,34858961,34842509,34841349,34841331,34840925,34839701,34813019,34782635,34777318,34772986,34766904,34751223,34733249,34721480,34710479,34702148,34696426,34696364,34691893,34690692,34681646,34673779,34668031,34659183,34606606,34606604,34606423,34605762,34605326,34593010,34589070,34572866,34541083,34489905,34487299,34479645,34450043,34435949,34413302,34409907,34406047,34393601,34386490,34372494,34371550,34367194,34335512,34310625,34261433,34244505,34204831,34198612,34197800,34197611,34183047,34178006,34174210,34164771,34163064,34160807,34133710,34122373,34093491,34089013,34076729,34076237,34066014,33990913,33990905,33970362,33953310,33941935,33923763,33920749,33920555,33902727,33868193,33867826,33854491,33839288,33837440,33805827,33805113,33804420,33800235,33797415,33777753,33750221,33748707,33741627,33710467,33679633,33677572,33614630,33595667,33590098,33585286,33578772,33575613,33571114,33569817,33557401,33544853,33495647,33472057,33468705,33451143,33444542,33442234,33428981,33401508,33391496,33388855,33375364,33346897,33332569,33330126,33290505,33256602,33251158,33250881,33239638,33230133,33226067,33218076,33217332,33214794,33203452,33193504,33193268,33193265,33192264,33185860,33172134,33167031,33152914,33137193,33122438,33105635,33102691,33102460,33095045,33083786,33079628,33077967,33076477,33068435,33067443,33066510,33015421,33004485,32999368,32991234,32983033,32973401,32960267,32953110,32939188,32913902,32903507,32903441,32895556,32888044,32883277,32832592,32826220,32817336,32793272,32784796,32781617,32761306,32760197,32751935,32735657,32729545,32727031,32676188,32670752,32669560,32647555,32643563,32580834,32572269,32572116,32561716,32556168,32541822,32539804,32528454,32519675,32516948,32467995,32453626,32411384,32408568,32401064,32397082,32393110,32385085,32377037,32371471,32368102,32363182,32353821,32349666,32334589,32327447,32325050,32296011,32284320,32271547,32221408,32203383,32200959,32198888,32195227,32190127,32186918,32174896,32170016,32156803,32132663,32096600,32051592,32038557,32038537,32028892,32013858,32010936,32006655,32006411,31998265,31998256,31980818,31969710,31956321,31937679,31937548,31921024,31919672,31914418,31879772,31872209,31862124,31858277,31857715,31852806,31811138,31797922,31791381,31784519,31775607,31768221,31762718,31756888,31748409,31745554,31740839,31729390,31717820,31711197,31708910,31695182,31689989,31677059,31666940,31647102,31646186,31624845,31611862,31611667,31572350,31569579,31558757,31555228,31551987,31548729,31546915,31541109,31540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Year	Number of Results
2015	16
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2018	154
2019	164
2020	134
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2024	24

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An updated evolutionary classification of CRISPR-Cas systems.

Makarova KS, Wolf YI, Alkhnbashi OS, Costa F, Shah SA, Saunders SJ, Barrangou R, Brouns SJ, Charpentier E, Haft DH, Horvath P, Moineau S, Mojica FJ, Terns RM, Terns MP, White MF, Yakunin AF, Garrett RA, van der Oost J, Backofen R, Koonin EV. Makarova KS, et al. Nat Rev Microbiol. 2015 Nov;13(11):722-36. doi: 10.1038/nrmicro3569. Epub 2015 Sep 28. Nat Rev Microbiol. 2015. PMID: 26411297 Free PMC article. Review.

Utilization of CRISPR-Cas genome editing technology in filamentous fungi: function and advancement potentiality.

Shen Q, Ruan H, Zhang H, Wu T, Zhu K, Han W, Dong R, Ming T, Qi H, Zhang Y. Shen Q, et al. Front Microbiol. 2024 Mar 28;15:1375120. doi: 10.3389/fmicb.2024.1375120. eCollection 2024. Front Microbiol. 2024. PMID: 38605715 Free PMC article. Review.

Precise genome-editing in human diseases: mechanisms, strategies and applications.

Zheng Y, Li Y, Zhou K, Li T, VanDusen NJ, Hua Y. Zheng Y, et al. Signal Transduct Target Ther. 2024 Feb 26;9(1):47. doi: 10.1038/s41392-024-01750-2. Signal Transduct Target Ther. 2024. PMID: 38409199 Free PMC article. Review.

The Cas10 nuclease activity relieves host dormancy to facilitate spacer acquisition and retention during type III-A CRISPR immunity.

Aviram N, Shilton AK, Lyn NG, Reis BS, Brivanlou A, Marraffini LA. Aviram N, et al. bioRxiv [Preprint]. 2024 Feb 12:2024.02.11.579731. doi: 10.1101/2024.02.11.579731. bioRxiv. 2024. PMID: 38405743 Free PMC article. Preprint.

CRISPR/Cas-based nucleic acid detection strategies: Trends and challenges.

Zhou J, Li Z, Seun Olajide J, Wang G. Zhou J, et al. Heliyon. 2024 Feb 14;10(4):e26179. doi: 10.1016/j.heliyon.2024.e26179. eCollection 2024 Feb 29. Heliyon. 2024. PMID: 38390187 Free PMC article. Review.

Impact of Homologous Recombination on Core Genome Evolution and Host Adaptation of Pectobacterium parmentieri.

Arizala D, Arif M. Arizala D, et al. Genome Biol Evol. 2024 Mar 2;16(3):evae032. doi: 10.1093/gbe/evae032. Genome Biol Evol. 2024. PMID: 38385549 Free PMC article.

Revolutionizing in vivo therapy with CRISPR/Cas genome editing: breakthroughs, opportunities and challenges.

Macarrón Palacios A, Korus P, Wilkens BGC, Heshmatpour N, Patnaik SR. Macarrón Palacios A, et al. Front Genome Ed. 2024 Feb 1;6:1342193. doi: 10.3389/fgeed.2024.1342193. eCollection 2024. Front Genome Ed. 2024. PMID: 38362491 Free PMC article. Review.

Identification of Family-Specific Features in Cas9 and Cas12 Proteins: A Machine Learning Approach Using Complete Protein Feature Spectrum.

Madugula SS, Pujar P, Bharani N, Wang S, Jayasinghe-Arachchige VM, Pham T, Mashburn D, Artilis M, Liu J. Madugula SS, et al. bioRxiv [Preprint]. 2024 Jan 23:2024.01.22.576286. doi: 10.1101/2024.01.22.576286. bioRxiv. 2024. PMID: 38328240 Free PMC article. Preprint.

Harnessing the endogenous Type I-C CRISPR-Cas system for genome editing in Bifidobacterium breve.

Han X, Chang L, Chen H, Zhao J, Tian F, Ross RP, Stanton C, van Sinderen D, Chen W, Yang B. Han X, et al. Appl Environ Microbiol. 2024 Mar 20;90(3):e0207423. doi: 10.1128/aem.02074-23. Epub 2024 Feb 6. Appl Environ Microbiol. 2024. PMID: 38319094 Free PMC article.

CRISPR/Cas9: an advanced platform for root and tuber crops improvement.

Divya K, Thangaraj M, Krishna Radhika N. Divya K, et al. Front Genome Ed. 2024 Jan 19;5:1242510. doi: 10.3389/fgeed.2023.1242510. eCollection 2023. Front Genome Ed. 2024. PMID: 38312197 Free PMC article. Review.

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