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Year Number of Results
2017 5
2018 6
2019 6
2020 1
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Page 1
Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.
Cheung KL, Zhang F, Jaganathan A, Sharma R, Zhang Q, Konuma T, Shen T, Lee JY, Ren C, Chen CH, Lu G, Olson MR, Zhang W, Kaplan MH, Littman DR, Walsh MJ, Xiong H, Zeng L, Zhou MM. Cheung KL, et al. Mol Cell. 2017 Mar 16;65(6):1068-1080.e5. doi: 10.1016/j.molcel.2016.12.022. Epub 2017 Mar 3. Mol Cell. 2017. PMID: 28262505 Free PMC article.
Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation.
Trivedi A, Mehrotra A, Baum CE, Lewis B, Basuroy T, Blomquist T, Trumbly R, Filipp FV, Setaluri V, de la Serna IL. Trivedi A, et al. Epigenetics Chromatin. 2020 Mar 10;13(1):14. doi: 10.1186/s13072-020-00333-z. Epigenetics Chromatin. 2020. PMID: 32151278 Free PMC article.
The Bromodomain Protein 4 Contributes to the Regulation of Alternative Splicing.
Uppal S, Gegonne A, Chen Q, Thompson PS, Cheng D, Mu J, Meerzaman D, Misra HS, Singer DS. Uppal S, et al. Cell Rep. 2019 Nov 19;29(8):2450-2460.e5. doi: 10.1016/j.celrep.2019.10.066. Cell Rep. 2019. PMID: 31747612 Free PMC article.
Bromodomain biology and drug discovery.
Zaware N, Zhou MM. Zaware N, et al. Nat Struct Mol Biol. 2019 Oct;26(10):870-879. doi: 10.1038/s41594-019-0309-8. Epub 2019 Oct 3. Nat Struct Mol Biol. 2019. PMID: 31582847 Free PMC article. Review.
The Histone Deacetylase SIRT6 Restrains Transcription Elongation via Promoter-Proximal Pausing.
Etchegaray JP, Zhong L, Li C, Henriques T, Ablondi E, Nakadai T, Van Rechem C, Ferrer C, Ross KN, Choi JE, Samarakkody A, Ji F, Chang A, Sadreyev RI, Ramaswamy S, Nechaev S, Whetstine JR, Roeder RG, Adelman K, Goren A, Mostoslavsky R. Etchegaray JP, et al. Mol Cell. 2019 Aug 22;75(4):683-699.e7. doi: 10.1016/j.molcel.2019.06.034. Epub 2019 Aug 6. Mol Cell. 2019. PMID: 31399344
The Cornelia de Lange Syndrome-associated factor NIPBL interacts with BRD4 ET domain for transcription control of a common set of genes.
Luna-Peláez N, March-Díaz R, Ceballos-Chávez M, Guerrero-Martínez JA, Grazioli P, García-Gutiérrez P, Vaccari T, Massa V, Reyes JC, García-Domínguez M. Luna-Peláez N, et al. Cell Death Dis. 2019 Jul 18;10(8):548. doi: 10.1038/s41419-019-1792-x. Cell Death Dis. 2019. PMID: 31320616 Free PMC article.
GSK2801, a BAZ2/BRD9 Bromodomain Inhibitor, Synergizes with BET Inhibitors to Induce Apoptosis in Triple-Negative Breast Cancer.
Bevill SM, Olivares-Quintero JF, Sciaky N, Golitz BT, Singh D, Beltran AS, Rashid NU, Stuhlmiller TJ, Hale A, Moorman NJ, Santos CM, Angus SP, Zawistowski JS, Johnson GL. Bevill SM, et al. Mol Cancer Res. 2019 Jul;17(7):1503-1518. doi: 10.1158/1541-7786.MCR-18-1121. Epub 2019 Apr 18. Mol Cancer Res. 2019. PMID: 31000582
The CDK9-cyclin T1 complex mediates saturated fatty acid-induced vascular calcification by inducing expression of the transcription factor CHOP.
Shiozaki Y, Okamura K, Kohno S, Keenan AL, Williams K, Zhao X, Chick WS, Miyazaki-Anzai S, Miyazaki M. Shiozaki Y, et al. J Biol Chem. 2018 Nov 2;293(44):17008-17020. doi: 10.1074/jbc.RA118.004706. Epub 2018 Sep 12. J Biol Chem. 2018. PMID: 30209133 Free PMC article.
JQ1 affects BRD2-dependent and independent transcription regulation without disrupting H4-hyperacetylated chromatin states.
Handoko L, Kaczkowski B, Hon CC, Lizio M, Wakamori M, Matsuda T, Ito T, Jeyamohan P, Sato Y, Sakamoto K, Yokoyama S, Kimura H, Minoda A, Umehara T. Handoko L, et al. Epigenetics. 2018;13(4):410-431. doi: 10.1080/15592294.2018.1469891. Epub 2018 Aug 6. Epigenetics. 2018. PMID: 30080437 Free PMC article.
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