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Commonly prescribed multi-medication therapies exert sex-specific effects on Alzheimer's disease pathology and metabolomic profiles in AppNL-G-F mice: Implications for personalized therapeutics in aging.
Eroli F, Johnell K, Acararicin Z, Tsagkogianni C, Zerial S, Lancia S, Latorre-Leal M, Alanko V, Hilmer SN, Matton A, Wastesson JW, Cedazo-Minguez A, Maioli S. Eroli F, et al. Alzheimers Dement. 2025 Mar;21(3):e70081. doi: 10.1002/alz.70081. Alzheimers Dement. 2025. PMID: 40145346 Free PMC article.
Machine learning reveals prominent spontaneous behavioral changes and treatment efficacy in humanized and transgenic Alzheimer's disease models.
Miller SR, Luxem K, Lauderdale K, Nambiar P, Honma PS, Ly KK, Bangera S, Bullock M, Shin J, Kaliss N, Qiu Y, Cai C, Shen K, Mallen KD, Yan Z, Mendiola AS, Saito T, Saido TC, Pico AR, Thomas R, Roberson ED, Akassoglou K, Bauer P, Remy S, Palop JJ. Miller SR, et al. Cell Rep. 2024 Nov 26;43(11):114870. doi: 10.1016/j.celrep.2024.114870. Epub 2024 Oct 19. Cell Rep. 2024. PMID: 39427315 Free PMC article.