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Cited In for PMID: 38477582

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Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein.
Ketcham JM, Harwood SJ, Aranda R, Aloiau AN, Bobek BM, Briere DM, Burns AC, Caddell Haatveit K, Calinisan A, Clarine J, Elliott A, Engstrom LD, Gunn RJ, Ivetac A, Jones B, Kuehler J, Lawson JD, Nguyen N, Parker C, Pearson KE, Rahbaek L, Saechao B, Wang X, Waters A, Waters L, Watkins AH, Olson P, Smith CR, Christensen JG, Marx MA. Ketcham JM, et al. J Med Chem. 2024 Mar 28;67(6):4936-4949. doi: 10.1021/acs.jmedchem.4c00078. Epub 2024 Mar 13. J Med Chem. 2024. PMID: 38477582 Free PMC article.
Free energy landscape of the PI3Kα C-terminal activation.
Kotzampasi DM, Papadourakis M, Burke JE, Cournia Z. Kotzampasi DM, et al. Comput Struct Biotechnol J. 2024 Jul 8;23:3118-3131. doi: 10.1016/j.csbj.2024.07.010. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 39229338 Free PMC article.