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Cited In for PMID: 40082451

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Structure-guided design of partial agonists at an opioid receptor.
Varga BR, Bernhard SM, El Daibani A, Zaidi SA, Lam JH, Aguilar J, Appourchaux K, Nazarova AL, Kouvelis A, Shinouchi R, Hammond HR, Eans SO, Weinreb V, Margolis EB, Fay JF, Huang XP, Pradhan A, Katritch V, McLaughlin JP, Majumdar S, Che T. Varga BR, et al. Nat Commun. 2025 Mar 13;16(1):2518. doi: 10.1038/s41467-025-57734-5. Nat Commun. 2025. PMID: 40082451 Free PMC article.
Structure-guided allosteric modulation of the delta opioid receptor.
Mobbs JI, Nguyen MD, Deo O, Bartuzi D, Venugopal H, Alvi S, Pham V, Barnes N, Christopoulos A, Poole DP, Carbone SE, Jörg M, Capuano B, Carlsson J, Gondin AB, Scammells PJ, Valant C, Thal DM. Mobbs JI, et al. bioRxiv [Preprint]. 2025 Oct 17:2025.10.16.682975. doi: 10.1101/2025.10.16.682975. bioRxiv. 2025. PMID: 41280124 Free PMC article. Preprint.
Antidepressants and the endogenous opioid system.
Fricker LD, Osman A, Gupta A, Gomes I, Devi LA. Fricker LD, et al. Biochem Pharmacol. 2025 Dec;242(Pt 4):117392. doi: 10.1016/j.bcp.2025.117392. Epub 2025 Oct 8. Biochem Pharmacol. 2025. PMID: 41072817 Review.
Synthesis and Pharmacology of a Morphinan-Derived Dual Mu-Kappa Opioid Receptor Agonist Analgesic.
Varga BR, Uprety R, Paul B, Knoll A, Ramos-Gonzalez N, Appourchaux K, Taylor T, Turgutalp B, Shinouchi R, Eans SO, Williams AK, Vasquez-Grinnell SG, Zaidi S, Nazarova AL, Varadi A, Le Rouzic V, Brown TG, Martinez S, Ansonoff M, Dardashti RN, Hunkele A, Subrath J, Welch M, Xu J, Rossi GC, Pintar J, Pasternak GW, Katritch V, McLaughlin JP, Pan YX, Majumdar S. Varga BR, et al. ACS Chem Neurosci. 2025 Jul 16;16(14):2714-2737. doi: 10.1021/acschemneuro.5c00312. Epub 2025 Jun 26. ACS Chem Neurosci. 2025. PMID: 40566691