Does caffeine intake protect from Alzheimer's disease?
Eur J Neurol. 2002.
PMID: 12099922
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The neuroprotective effects of caffeine in neurodegenerative diseases.
CNS Neurosci Ther. 2017 Apr;23(4):272-290. doi: 10.1111/cns.12684.
CNS Neurosci Ther. 2017.
PMID: 28317317
Free PMC article.
Review.
In Alzheimer's disease (AD), caffeine is beneficial in both men and women, in humans and animals. Similar effects of caffeine were observed in men with Parkinson's disease (PD); however, the effect of caffeine in female PD p …
In Alzheimer's disease (AD), caffeine is beneficial in both men and women, in humans and animals. Similar effect …
Neuroprotective Effects of Coffee Bioactive Compounds: A Review.
Int J Mol Sci. 2020 Dec 24;22(1):107. doi: 10.3390/ijms22010107.
Int J Mol Sci. 2020.
PMID: 33374338
Free PMC article.
Review.
Extensive research shows that coffee consumption appears to have beneficial effects on human health. Regular coffee intake may protect from many chronic disorders, including cardiovascular disease, type 2 diabetes, obesity, and some types of cancer. Important …
Extensive research shows that coffee consumption appears to have beneficial effects on human health. Regular coffee intake may pro …
Nutrition and prevention of cognitive impairment.
Lancet Neurol. 2018 Nov;17(11):1006-1015. doi: 10.1016/S1474-4422(18)30338-7. Epub 2018 Sep 21.
Lancet Neurol. 2018.
PMID: 30244829
Review.
Some, but not conclusive, evidence (mostly from observational studies and infrequently from clinical trials) exists of a protective association between certain nutrients (eg, folate, flavonoids, vitamin D, and certain lipids) or food groups (eg, seafood, vegetables, and fr …
Some, but not conclusive, evidence (mostly from observational studies and infrequently from clinical trials) exists of a protective a …
Potential of Caffeine in Alzheimer's Disease-A Review of Experimental Studies.
Nutrients. 2021 Feb 6;13(2):537. doi: 10.3390/nu13020537.
Nutrients. 2021.
PMID: 33562156
Free PMC article.
Review.
Alzheimer's disease (AD) is the most common type of dementia leading to progressive memory loss and cognitive impairment. ...Although epidemiological data suggest that caffeine intake may counteract the development of cognitive impairment, resul …
Alzheimer's disease (AD) is the most common type of dementia leading to progressive memory loss and cognitive impairmen …
Does caffeine intake protect from Alzheimer's disease?
Eur J Neurol. 2002 Jul;9(4):377-82. doi: 10.1046/j.1468-1331.2002.00421.x.
Eur J Neurol. 2002.
PMID: 12099922
If caffeine intake could protect against neurodegeneration in Alzheimer's disease (AD), then higher levels of caffeine consumption in normal subjects as compared with AD patients should be detectable in the presumably long period b …
If caffeine intake could protect against neurodegeneration in Alzheimer's disease (AD), then highe …
Caffeine and coffee as therapeutics against Alzheimer's disease.
J Alzheimers Dis. 2010;20 Suppl 1:S117-26. doi: 10.3233/JAD-2010-091249.
J Alzheimers Dis. 2010.
PMID: 20182037
Review.
Epidemiologic studies have increasingly suggested that caffeine/coffee could be an effective therapeutic against Alzheimer's disease (AD). ...These results indicate a surprising ability of moderate caffeine intake (the human equivalent of …
Epidemiologic studies have increasingly suggested that caffeine/coffee could be an effective therapeutic against Alzheimer' …
The Neuroprotective Effects of Moderate and Regular Caffeine Consumption in Alzheimer's Disease.
Oxid Med Cell Longev. 2021 Aug 17;2021:5568011. doi: 10.1155/2021/5568011. eCollection 2021.
Oxid Med Cell Longev. 2021.
PMID: 34447487
Free PMC article.
Review.
The increasing numbers of elderly Alzheimer's disease (AD) patients because of a steady increase in the average lifespan and aging society attract great scientific concerns, while there were fewer effective treatments on AD progression due to unclear exact ca …
The increasing numbers of elderly Alzheimer's disease (AD) patients because of a steady increase in the average lifespa …
Methylxanthines and Neurodegenerative Diseases: An Update.
Nutrients. 2021 Feb 28;13(3):803. doi: 10.3390/nu13030803.
Nutrients. 2021.
PMID: 33671099
Free PMC article.
Review.
By affecting several pathways associated with neurodegenerative diseases via different pleiotropic mechanisms and due to its moderate side effects, intake of methylxanthines have been suggested to be an interesting approach in dealing with neurodegeneration. ...In this rev …
By affecting several pathways associated with neurodegenerative diseases via different pleiotropic mechanisms and due to its moderate side e …
Role of Caffeine in the Age-related Neurodegenerative Diseases: A Review.
Mini Rev Med Chem. 2022;22(21):2726-2735. doi: 10.2174/1389557522666220413103529.
Mini Rev Med Chem. 2022.
PMID: 35422212
Review.
Intake of coffee containing edibles for a long period or even for a substantial part of life makes caffeines impact significant. Low acute and chronic toxicity of caffeine is another important specification. The discoveries from the last few years point to th …
Intake of coffee containing edibles for a long period or even for a substantial part of life makes caffeines impact significan …
Glutathione-Mediated Neuroprotective Effect of Purine Derivatives.
Int J Mol Sci. 2023 Aug 22;24(17):13067. doi: 10.3390/ijms241713067.
Int J Mol Sci. 2023.
PMID: 37685879
Free PMC article.
Review.
Numerous basic studies have reported on the neuroprotective properties of several purine derivatives such as caffeine and uric acid (UA). Epidemiological studies have also shown the inverse association of appropriate caffeine intake or serum urate levels with …
Numerous basic studies have reported on the neuroprotective properties of several purine derivatives such as caffeine and uric acid ( …
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