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Page 1
. 2025 Jun;52(3):289-298.
doi: 10.1177/10901981241307616. Epub 2024 Dec 30.

Health Literacy Among Sexual and Gender-Diverse Adolescents in New York City

Affiliations

Health Literacy Among Sexual and Gender-Diverse Adolescents in New York City

Abby Marshall et al. Health Educ Behav. 2025 Jun.

Abstract

This study explored sexual orientation and gender identity as predictors of health literacy among adolescents attending New York City (NYC) public high schools. Many studies have demonstrated disparities in sexual health among sexual and gender minority (SGM) adolescents. However, little is known about their health literacy. Health literacy, defined as the capacity to acquire, understand, appraise, and apply health information, especially in health decision-making, is a known predictor of health. Data came from a quantitative cross-sectional survey (N = 1,438) collected at 15 high schools in the Bronx, NYC. Four aspects of health literacy were explored: (1) knowledge of sexually transmitted infections (STIs), (2) knowledge of sexual health rights in New York State, (3) health access literacy and self-efficacy, and (4) health communication. Linear regression analysis was used to test predictors of health literacy. Contrary to our hypothesis, SGM adolescents did not score significantly lower on the health literacy variables compared with cisgender heterosexual adolescents. SGM adolescents scored significantly higher on knowledge of STIs and knowledge of health rights compared with cisgender heterosexual young men. Adolescents who were questioning their sexual identity scored significantly lower compared with both SGM and cisgender heterosexual adolescents on all four health literacy scales. Interventions are needed to ensure that in-school curricula are inclusive and address health literacy among questioning adolescents and cisgender heterosexual young men. Addressing the health needs of questioning adolescents is particularly important because adolescence is a critical time of decision-making around sexuality and health.

Keywords: health literacy; sexual and gender minority adolescents.

Conflict of interest statement

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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. 2025 May 12:13:e19394.
doi: 10.7717/peerj.19394. eCollection 2025.

A cross-sectional study evaluating insulin injection techniques and the impact of instructions from various healthcare professionals on insulin users in the southern region of Saudi Arabia

Affiliations

A cross-sectional study evaluating insulin injection techniques and the impact of instructions from various healthcare professionals on insulin users in the southern region of Saudi Arabia

Sirajudeen Shaik Alavudeen et al. PeerJ. .

Abstract

Background: It is evident that proper use of the insulin injection technique (IIT) is important for optimizing the efficacy of the therapy. Despite the readily available manufacturers' instructions, healthcare professionals (HCPs) play a major role in educating patients. This study aims to investigate the knowledge, practices, and challenges faced by insulin users regarding IIT, as well as the impact of healthcare professionals' education on it.

Methods: We conducted a questionnaire-based cross-sectional study using a validated online questionnaire to gather demographic and clinical data, as well as the participants' knowledge, practices, and challenges related to insulin therapy.

Results: The mean age of the participants was 38.25 ± 15.58 (mean ± SD) years, with a nearly equal distribution of genders. Thirty-six percent of the participants educated by the diabetes educators demonstrated an appropriate IIT, such as storage, priming the insulin pen (54%), skin folding (63%), injection hold time, and "use-by" date. Furthermore, the absence of diabetes education specialist training increases the likelihood of errors, potentially leading to a loss of glycemic control. Patients reported carrying insulin when traveling as one of the major challenges (27.9%), followed by timely injections (23.7%), priming (21.6%), and adjusting the insulin dose (16.8%). Forgetfulness (47.7%), traveling or altering the regular routine (15.5%), missing a meal (15.5%), and being overly busy (13.5%) were among the reasons for missing the insulin dose; all of which are easily manageable with proper education.

Conclusion: Consistent education and re-education are necessary for the insulin users to resolve the issues associated with suboptimal IIT. The inclusion of all stakeholders in insulin therapy, particularly the diabetes education specialists, is essential. Therefore, the Ministry of Health in Saudi Arabia should take the initiative to ensure that appropriately trained diabetes education specialists, pharmacists, nurses and other HCPs assess and follow up on patients.

Keywords: Barriers; Diabetes education; Diabetes mellitus; Healthcare professionals; Insulin injection technique.

Conflict of interest statement

The authors declare there are no competing interests.

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. 2025 May;21(5):e70257.
doi: 10.1002/alz.70257.

Co-design of medication management guidance tools for people living with dementia and carers at discharge

Affiliations

Co-design of medication management guidance tools for people living with dementia and carers at discharge

Mouna J Sawan et al. Alzheimers Dement. 2025 May.

Abstract

Introduction: People with dementia and carers face challenges in understanding and managing medications at discharge. This study aimed to develop user-centered, co-designed medication management guidance tools to enhance medication management literacy post-hospitalization for these populations.

Methods: A four-phase, multi-methods study integrating experience-based co-design: (1) literature review, qualitative study, and survey; (2) expert advisory panels involving people with dementia; (3) focus groups with people with dementia, carers, and healthcare professionals; and (4) quantitative readability and suitability analysis.

Results: Two tools were developed: a simplified medication management guide for people with dementia and a carer-focused guide. Topics included shared decision-making, informed consent, and medications that can affect cognition. Participants valued the use of simple and active language, goal-of-care discussions, and the right to second opinion. Tools were acceptable for use from admission and during hospitalization.

Discussion: This study addresses gaps in medication related health literacy tools for dementia care, offering a framework for developing similar resources.

Highlights: Medication management guidance tools have not included people living with dementia or their carers in their development. This study is the first to describe the co-design of medication management guidance tools for people with dementia. Two tools were generated, one for people with dementia and one for carers to extend their agency. This co-design study can serve as a framework to inform the development of future tools for people with dementia and carers.

Keywords: care coordination; dementia care; health literacy; patient communication; shared decision making.

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. 2025;96(5):664-672.
doi: 10.62713/aic.3945.

Effects of Interactive Health Education Combined With Evidence-based Pain Management Nursing on Disease Cognition, Postoperative Pain and Post-traumatic Growth in Patients Undergoing Laparoscopic Salpingectomy

Affiliations

Effects of Interactive Health Education Combined With Evidence-based Pain Management Nursing on Disease Cognition, Postoperative Pain and Post-traumatic Growth in Patients Undergoing Laparoscopic Salpingectomy

Ye Cheng et al. Ann Ital Chir. 2025.

Abstract

Aim: Laparoscopic salpingectomy has been widely used in the clinical treatment of benign tubal lesions. This study aims to explore the effects of interactive health education combined with evidence-based pain management nursing on disease cognition, postoperative pain and post-traumatic growth in patients undergoing laparoscopic salpingectomy, in order to provide new insights into clinical nursing for these patients.

Methods: In this retrospective study, 360 patients who underwent laparoscopic salpingectomy in our hospital from January 2022 to December 2023 were included. Patients receiving routine care were included in the control group (n = 213) and patients receiving interactive health education combined with evidence-based pain care were classified under the study group (n = 147). General data, disease cognition, postoperative pain and post-traumatic growth of the two groups were collected and compared.

Results: The awareness rate regarding pathogenesis, cardinal symptom, surgical and postoperative precautions, prevention of complications, medication management, diet management, sleep management, and review time and project in the study group were all significantly higher than those in the control group (p < 0.05). The numerical rating scale (NRS) scores of the study group were lower than those of the control group at 6 h, 12 h, 24 h and 48 h post-surgery (p < 0.001). Before discharge, all dimensions of the post-traumatic growth inventory (PTGI) scores like relating to others, new possibilities, personal strength, spiritual change, and appreciation of life of the study group patients were significantly higher than those of the control group (p < 0.05). The time to get out of bed, exhaust time, and hospitalization stay of the study group patients were significantly shorter than those of the control group (p < 0.05). The total incidence of complications in the study group was significantly lower than that in the control group (p < 0.05).

Conclusions: Interactive health education combined with evidence-based pain management nursing is conducive to improving disease cognition, reducing postoperative pain, enhancing post-traumatic growth, and promoting postoperative recovery in patients undergoing laparoscopic salpingectomy.

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. 2025 May 15;25(1):343.
doi: 10.1186/s12877-025-06003-7.

Factors associated with mental health literacy and demand for mental health services among older adults in China: a cross-sectional study

Affiliations

Factors associated with mental health literacy and demand for mental health services among older adults in China: a cross-sectional study

Haihui Chen et al. BMC Geriatr. .

Abstract

Background: There is limited research on mental health literacy (MHL) among Chinese older adults as well as their demand and willingness for mental health services (MHS). This study investigated the factors associated with them among Chinese older adults. Additionally, predictors of MHL as well as demand and willingness for MHS were compared between older adults living alone and those not living alone.

Methods: This study is a cross-sectional study conducted among 494 older adults in Guangzhou, China. Sociodemographic characteristics, frequency of participating in community-based activities, mental health status, MHL, and demand and willingness for MHS were assessed through self-reported questions. A series of logistic regression analyses were conducted to examine factors associated with the MHL and demand and willingness for MHS.

Results: The awareness rates for the three MHL-related questions were between 65.3% and 73.7%, and 62.0% and 69.6% of the participants indicated the demand and willingness, respectively, for MHS. Frequently participating in community-based activities increased the likelihood of awareness of the MHL-related questions (ORs = 2.92-4.18, CIs = [1.50,9.28]), as well as the demand and willingness for MHS (ORs = 2.16-2.24, CIs = [1.19,4.20]). Similar significant associations were found among the older adults who were not living alone but not among those living alone.

Conclusions: Based on the results of this study, policymakers and clinicians are advised to develop more targeted community-based activities for older adults and focus especially on those living alone to enhance their MHL and increase willingness for MHS.

Keywords: Chinese context; Community-based activity; Demand for mental health services; Mental health literacy; Willingness for mental health services.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: All participants provided written informed consent and were informed that they had the right to withdraw at any time. This study was carried out in accordance with the Helsinki Declaration as revised in 1989 and was approved by the Ethics Committees of South China Normal University (SCNU-PSY-2023-005). Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

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. 2025 May 15:1-9.
doi: 10.1080/14670100.2025.2500830. Online ahead of print.

Cochlear implant services for Spanish speaking patients: language access and organizational health literacy of programs in the United States of America

Affiliations

Cochlear implant services for Spanish speaking patients: language access and organizational health literacy of programs in the United States of America

Alejandra Ullauri et al. Cochlear Implants Int. .

Abstract

Objective: To examine the accessibility of online information about cochlear implant (CI) services for Spanish speakers and evaluate organizational health literacy practices in CI programs in the United States (USA).

Method: From a list provided by Cochlear, CI programs working with at least two of three CI manufacturers were identified in eight states. Selected states had the highest and lowest Hispanic populations in each of the four US geographic regions. Online information access was evaluated based on whether programs' website links were a) listed on manufacturers' 'Find-a-Clinic' tabs, b) led directly to the CI program website, c) provided information about CIs in Spanish, and d) the readability level of such information. To examine language access, researchers determined if listed programs' phone numbers connected to the department providing CI services and the availability of Spanish speaking schedulers, audiologists, ENT surgeons, and professional interpreters (PIs).

Results: 122 CI programs met the inclusion criteria. Only 4-9% of listed programs had a link connecting directly to the CI program's website, and only 11% had Spanish-language CI information. Spanish text averaged 10th grade readability (Flesch-Kincaid). Phone contacts showed 78% of numbers connected directly to the ENT/Audiology department, while only 27% offered an initial Spanish option. PIs were available in 68% of programs.

Conclusions: Results indicate reduced language access for Spanish speakers seeking CI services in the USA, exemplified by limited access to PIs and bilingual providers, insufficient availability of information about CIs on programs' websites, and low organization health literacy practices in CI programs.

Keywords: Cochlear implants; Hispanic population; Spanish speakers.

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. 2025 May 15;20(5):e0322181.
doi: 10.1371/journal.pone.0322181. eCollection 2025.

Navigational health literacy and health service use among higher education students in Alentejo, Portugal - A cross-sectional study

Affiliations

Navigational health literacy and health service use among higher education students in Alentejo, Portugal - A cross-sectional study

Jorge Rosário et al. PLoS One. .

Abstract

Introduction: The navigational health literacy of higher education students is fundamental to effective health management and successful health navigation, thereby improving health outcomes and overall well-being. Assessing the general and navigational health literacy levels of these students is crucial for developing targeted interventions and facilitating informed decision-making on health-related issues. This study aimed to identify the levels of general and navigational health literacy, characterise access to and utilisation of healthcare services, and analyse the differences between the mean general and navigational health literacy indices and determinants among higher education students in the Alentejo region of southern Portugal.

Methodology: A descriptive and cross-sectional study was conducted between 25 May and 12 September 2023 with 1979 higher education students. An online structured questionnaire comprising the Portuguese version of the European Health Literacy Survey Questionnaire - 16 items (HLS-EU-PT-Q16) and the Navigational Health Literacy Scale (HLS19-NAV), both from the European Consortium, was used. Sociodemographic data, presence of chronic disease, perceived health status, perceived availability of money for expenses, and healthcare access and utilisation variables were included. The study data were analysed using independent samples t-test, one-way ANOVA, and post hoc Bonferroni test, followed by multiple linear regression analyses at a significance level of 0.05. Multiple linear regression analysis was performed to identify factors associated with both general and navigational health literacy. The study protocol was approved by the ethics committee of the University of Évora, and all participants provided written informed consent.

Results: Most students (86.8%) exhibited limited general health literacy, while 13.2% demonstrated adequate health literacy. Inadequate navigational health literacy was observed in 73.4% of students. Students with lower mean general and navigational health literacy were more likely to have utilised health services. Students with chronic conditions, recent use of urgent or emergency services, and difficulties in accessing healthcare had lower health literacy. Conversely, those enrolled in health-related courses, those with good financial resources and those who had not used health services during their course had higher health literacy. In addition, lower navigational health literacy was found among displaced students, those with chronic conditions and those who had recently consulted a doctor. Higher navigational health literacy was associated with enrolment in health-related courses and adequate general health literacy.

Conclusion: The findings highlight the significant influence of demographic and academic factors on general and navigational health literacy among higher education students. The prevalence of limited general and navigational health literacy underscores a significant challenge for students, institutions, and health policy makers. Effective health literacy interventions should take these factors into account. Future research should examine longitudinal changes in health literacy and evaluate the impact of targeted educational programmes.

Conflict of interest statement

The authors have declared that no competing interests exist.

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Randomized Controlled Trial
. 2025 May 15;43(1):305.
doi: 10.1007/s00345-025-05690-6.

Video-assisted education for informed consent in percutaneous nephrolithotomy: a prospective study on patient comprehension

Affiliations
Randomized Controlled Trial

Video-assisted education for informed consent in percutaneous nephrolithotomy: a prospective study on patient comprehension

Mucahit Gelmis et al. World J Urol. .

Abstract

Purpose: The prevalence of urinary stone disease is increasing due to climate change, dietary habits, and obesity. Percutaneous nephrolithotomy (PCNL) remains the preferred treatment for large kidney stones. The informed consent process is essential for patient understanding; however, conventional verbal and written methods may be inadequate. This study aimed to evaluate the effectiveness of video-assisted education in improving informed consent for PCNL.

Methods: This randomized controlled study was conducted from January to July 2023. Eighty patients scheduled for PCNL were randomly assigned to either a written-consent-only group or a video-assisted consent group that received both written consent and a seven-minute 3D-animated video. Comprehension was assessed using a 17-question knowledge assessment questionnaire before and after the consent process. Improvements in knowledge and differences in comprehension were compared.

Results: The video-assisted consent group showed significantly greater comprehension improvement than the written-only group, benefiting patients across all education levels. Multivariate analysis confirmed the strong association between video education and knowledge gain, though older age was linked to lower improvement. Despite its effectiveness, two patients withdrew due to increased anxiety, underscoring the need to balance understanding with emotional reassurance.

Conclusion: Video-assisted informed consent significantly improves comprehension in PCNL patients, particularly in those with lower education levels. However, an increased awareness of surgical risks may contribute to preoperative anxiety. Future research should refine video content, assess long-term outcomes, and explore strategies to balance comprehension with emotional reassurance.

Keywords: Educational video; Informed consent; PCNL; Patient understanding; Percutaneous nephrolithotomy.

Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests.

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Review
. 2025 May 15;53(1):92.
doi: 10.1007/s00240-025-01761-w.

What is the role of large language models in the management of urolithiasis?: a review

Affiliations
Review

What is the role of large language models in the management of urolithiasis?: a review

Tunahan Ates et al. Urolithiasis. .

Abstract

This review aimed to investigate the role of large language models (LLMs) in clinical decision support, patient counseling, and patient education in the management of urolithiasis. Eleven eligible studies were assessed following a comprehensive search of the Scopus and Web of Science databases. In the realm of clinical decision support, large language models (LLMs), particularly ChatGPT-4, have shown efficacy in areas such as the diagnosis of urolithiasis and initial treatment planning. An evaluation of the models' adherence to the European Association of Urology guidelines revealed that ChatGPT and Perplexity outperformed Bard. For patient counseling, Bing AI exhibited a robust capacity to deliver resource-based information. The studies have yielded conflicting results regarding ChatGPT versions' ability to empathize. In the context of patient education, models such as Claude-3 and ChatGPT-4 have demonstrated the capability to provide accurate and comprehensible answers to patient questions. However, it was noted that the quality of information is occasionally conveyed using complex language. LLMs have considerable potential as assistive tools in the management of urolithiasis; however, their limitations necessitate expert supervision, especially in complex cases. In the future, it is anticipated that these limitations will be mitigated through improved training and integration of these models into clinical practice. Consequently, LLMs should be employed as auxiliary tools rather than primary instruments in clinical decision-making.

Keywords: Clinical decision support; LLMs; Large language model; Patient counseling; Patient education; Review; Urolithiasis.

Conflict of interest statement

Declarations. Ethics approval: This study did not require ethics committee approval because it did not involve direct interaction with human participants. Informed consent: Not applicable. Competing interests: The authors declare no competing interests.

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. 2025 May 15:7334648251338875.
doi: 10.1177/07334648251338875. Online ahead of print.

Dementia Care Partner Health Literacy as a Mediator Between Education and Burden at Hospital Discharge

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Dementia Care Partner Health Literacy as a Mediator Between Education and Burden at Hospital Discharge

Ashley Kuzmik et al. J Appl Gerontol. .

Abstract

Care partners of hospitalized persons with dementia often experience significant burden at discharge. This study examined whether dementia care partner health literacy mediates the relationship between education and burden at hospital discharge. Data from 277 care partners in the Family-centered Function-focused Care (Fam-FFC) trial were analyzed using mediation analysis to assess indirect effects of education on burden (Short-Form Zarit Burden Interview [ZBI-12]) through health literacy (Rapid Estimate of Adult Literacy in Medicine-Short Form [REALM-SF]). Analyses were conducted using SPSS and AMOS. For medium education (B = -0.012; 95% CI = -0.019, -0.003), the indirect effect accounted for 18.5% of the total effect, while for high education (B = -0.018; 95% CI = -0.026, -0.006), it accounted for 21.4%, indicating partial mediation. Findings underscore the role of health literacy in reducing care partner burden and highlight the need to address education and literacy disparities to provide effective support at hospital discharge.

Keywords: care partner burden; education level; health literacy; hospital discharge.

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Review
. 2025 May 15:122:24138.

[Asthma in primary care]

[Article in Swedish]
Affiliations
  • PMID: 40371568
Free article
Review

[Asthma in primary care]

[Article in Swedish]
Hanna Sandelowsky et al. Lakartidningen. .
Free article

Abstract

Primary care is responsible for diagnostics and follow-up of the majority of patients with asthma. The variable airway obstruction may contribute to difficulties in diagnosing asthma. The cornerstones of diagnostics are patient history and lung function measurements. Even patients with only sporadic symptoms should be treated with inhaled corticosteroids (Step 1 in the asthma treatment track). Patient education is essential for good asthma control. Optimal asthma control means normal lung function, absence of symptoms and absence of exacerbations. This must always be assessed at a patient consultation. In uncontrolled asthma, treatment barriers such as inadequate inhalation technique, insufficient adherence to treatment, exposure to asthma triggers, and possible influence of co-morbidity should be assessed.

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. 2025 Apr 30:13:1551197.
doi: 10.3389/fpubh.2025.1551197. eCollection 2025.

Parental first aid literacy in epistaxis: do parents know what to do?

Affiliations

Parental first aid literacy in epistaxis: do parents know what to do?

Alya AlZabin et al. Front Public Health. .

Abstract

Background: Epistaxis is a common otorhinolaryngology emergency, especially among the pediatric population. While prompt first aid is essential, there is limited data on parents' knowledge regarding its management in Saudi Arabia. This study assessed parental literacy in epistaxis first aid and its correlation with sociodemographic factors.

Methods: A cross-sectional online study was conducted from May to June 2023, targeting parents of children aged ≤12 years across Saudi Arabia. Using a structured questionnaire, data on demographic characteristics and epistaxis first aid knowledge were collected from 777 participants. Descriptive statistics and binary logistic regression were utilized for analysis.

Results: The majority of parents (79%) reported that their child had experienced epistaxis, and 72.7% considered it an emergency. However, knowledge gaps were evident: only 15.8% recognized posterior bleeds as life-threatening, and just 54.8% identified the correct position for managing epistaxis. Geographic disparities were noted, with parents in the South, East, and North showing lower literacy than those in the Western region. Additionally, male, non-Saudi, and postgraduate parents had reduced literacy regarding epistaxis prevention. A large proportion of parents relied on the internet for information, which may contribute to these gaps.

Conclusion: There is a significant need for targeted educational programs to improve parental knowledge of epistaxis first aid, particularly among specific demographic groups. Enhancing access to first-aid training and credible resources could improve emergency responses to epistaxis, mitigating risks and promoting safer outcomes for children.

Keywords: Saudi Arabia; epistaxis; first aid; nosebleed; otorhinolaryngology; parents.

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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. 2025 Apr 30:13:1510035.
doi: 10.3389/fpubh.2025.1510035. eCollection 2025.

Developing a model of interactive health literacy among college students majoring in kinesiology: a grounded theory approach

Affiliations

Developing a model of interactive health literacy among college students majoring in kinesiology: a grounded theory approach

Miaomiao Wen et al. Front Public Health. .

Abstract

Background: Health literacy among college students majoring in kinesiology is higher than that among students in other majors. However, the structure of interactive health literacy is poorly understood, which may affect overall health literacy. Despite existing research on health literacy, studies targeting college students majoring in kinesiology are scarce, and a gap remains in translating study results into practical strategies. Therefore, this study constructed a theoretical model of interactive health literacy among college students majoring in kinesiology.

Methods: Qualitative data were collected from online posts, a literature review, and semi-structured interviews with 11 college students majoring in kinesiology, physical education teachers, and six physical fitness experts in China. Participants were selected using purposive sampling. Interview questions focused on participants' perceptions of the structure and characteristics of interactive health literacy among college students majoring in kinesiology. Data were analyzed based on the grounded theory.

Results: The analysis derived three categories with eight subcategories, 60 concepts, and 288 labels. The categories and subcategories were harnessing health information (comprising obtaining health information and comprehending health information), promoting health interactions (comprising perceiving health functions, shaping health awareness, and participating in health communication), and addressing health problems (comprising forming health motivation, making healthy decisions, and practicing healthy living).

Conclusions: College students majoring in kinesiology in China exhibited unique trends in interactive health literacy compared to students in other countries. Further large-scale surveys are required to revise and validate the initial exploration of perceptions and investigate the structural system of interactive health literacy in various groups.

Keywords: China; grounded theory; interactive health literacy; kinesiology; sports.

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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. 2025 Apr 30:13:1558772.
doi: 10.3389/fpubh.2025.1558772. eCollection 2025.

Adoption challenges to artificial intelligence literacy in public healthcare: an evidence based study in Saudi Arabia

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Adoption challenges to artificial intelligence literacy in public healthcare: an evidence based study in Saudi Arabia

Rakesh Kumar et al. Front Public Health. .

Abstract

In recent years, Artificial Intelligence (AI) is transforming healthcare systems globally and improved the efficiency of its delivery. Countries like Saudi Arabia are facing unique adoption challenges in their public healthcare, these challenges are specific to AI literacy, understanding and effective usage of AI technologies. In addition, cultural, regulatory and operational barriers increase the complication of integrating AI literacy into public healthcare operations. In spite of its critical contribution in enabling sustainable healthcare development, limited studies have addressed these adoption challenges. Our study explores the AI literacy adoption barriers in context to Saudi Arabian public healthcare sector, focusing on its relevance for advancing healthcare operations and achieving Sustainable Development Goals (SDGs). The research aims to identifying and addressing the adoption challenges of Artificial Intelligence literacy within the public healthcare in Saudi Arabia. The research aims to enhance the understanding of AI literacy, its necessity for enhancing healthcare operations, and the specific hurdles that impede its successful AI adoption in Saudi Arabia's public healthcare ecosystem. The research employs a qualitative analysis using the T-O-E framework to explore the adoption challenges of AI literacy. Additionally, the Best-Worse Method (BWM) is applied to evaluate the adoption challenges to AI literacy adoption across various operational levels within Saudi Arabia's public healthcare supply chain. The study uncovers substantial adoption challenges at operational, tactical, and strategic level, including institutional readiness, data privacy, and compliance with regulatory frameworks. These challenges complicate the adoption of AI literacy in the Saudi public healthcare supply chains. The research offers critical insights into the various issues affecting the promotion of AI literacy in Saudi Arabia's public healthcare sector. This evidence-based study provides essential commendations for healthcare professionals and policymakers to effectively address the identified challenges, nurturing an environment beneficial to the integration of AI literacy and advancing the goals of sustainable healthcare development.

Keywords: AI literacy; Saudi Arabia; Sustainable Development Goals; adoption challenges; artificial intelligence; public healthcare.

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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. 2025 May 14.
doi: 10.1111/jocn.17807. Online ahead of print.

Self-Efficacy and e-Health Literacy Among Caregivers of Patients With Lung Cancer: The Chain-Mediating Roles of Negative Emotions and Caregiver Readiness

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Self-Efficacy and e-Health Literacy Among Caregivers of Patients With Lung Cancer: The Chain-Mediating Roles of Negative Emotions and Caregiver Readiness

Jiali Wu et al. J Clin Nurs. .

Abstract

Objectives: To explore the chain-mediating roles of negative emotions and caregiver readiness between self-efficacy and e-health literacy among caregivers of patients with lung cancer.

Background: With the rise of Internet health services, caregivers of patients with lung cancer, who are one of the health decision makers, are encountering new challenges. In order to develop appropriate interventions, it is necessary to explore in depth the various influencing factors associated with them.

Design: A cross-sectional survey.

Methods: A total of 293 caregivers of patients with lung cancer were recruited between November 2023 and April 2024 through a convenience sampling method. These participants completed the demographic data questionnaire, General Self-Efficacy Scale (GSES), Hospital Anxiety and Depression Scale (HADS), Caregivers Preparedness Scale (CPS), and eHealth Literacy Scale (eHEALS). Independent samples t-tests and a one-way ANOVA were employed to identify the primary influencing factors. Structural equation modelling was employed to detect the mediating effects of negative emotions and caregiver readiness.

Reporting method: The STROBE checklist was used for this study.

Results: The total e-health literacy score of caregivers of patients with lung cancer was 29.65 ± 7.11, and there was a correlation between self-efficacy, negative emotions, caregiver readiness, and e-health literacy. The results of the path analysis showed that negative emotions and caregiver readiness had chain-mediating roles between self-efficacy and e-health literacy among caregivers of patients with lung cancer, with the total indirect effect accounting for 31.17% of the total effect.

Conclusions: Caregivers of patients with lung cancer exhibit moderate levels of e-health literacy. This research suggests that self-efficacy not only has a direct and positive influence on e-health literacy but may also amplify it by mediating the interplay between negative emotions and caregiver readiness.

Relevance to clinical practice: Healthcare providers should be cognizant of the negative emotions and readiness displayed by family caregivers in the hospital setting to aid them in cultivating strong health literacy for more efficient management of illness care tasks.

Patient or public contribution: Nurses at the hospitals assisted us in collecting data from family caregivers of patients with lung cancer, and the caregivers actively cooperated in completing the questionnaires.

Keywords: caregiver readiness; caregivers; health literacy; mediation effect; negative emotions; self‐efficacy.

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. 2025 May 14.
doi: 10.1111/jocn.17811. Online ahead of print.

Digital Health Literacy in Patients With Hypertension: A Cross-Sectional Study

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Digital Health Literacy in Patients With Hypertension: A Cross-Sectional Study

Melania Totaro et al. J Clin Nurs. .

Abstract

Aim: To assess Digital Health Literacy (DHL) levels among hypertensive patients.

Design: Cross-sectional study.

Methods: The study, conducted from March to August 2024 among hypertensive patients using convenience sampling, employed a 35-item questionnaire assessing: (I) sociodemographic; (II) physical activity, dietary habits, antihypertensive pharmacological treatment and medical history; (III) online health-related information knowledge and confidence; (IV) DHL, through the HLS19-DIGI questionnaire with subscales on: (i) dealing with digital health information (HL-DIGI), (ii) interaction with digital resources (HL-DIGI-INT), (iii) frequency of digital device use for health (HL-DIGI-DD).

Results: Among 311 participants (mean age 63.9 years, SD = 14.8), 42.1% completed high school, 25.4% held a bachelor's degree and 22.8% were physically inactive. While 49.8% were aware of online health-related information, 28.9% were uncertain and 47.6% lacked confidence in using it for health decisions. On average, participants showed a problematic level of DHL in HL-DIGI, a sufficient level in HL-DIGI-INT, and used digital health devices just over once a week. Older age emerged as a predictor of higher online health-related knowledge and DHL, while higher education level predicted higher knowledge, confidence and DHL. Physical inactivity was associated with lower online health-related information knowledge and confidence.

Conclusions: These findings point to the need to design proactive strategies and implement targeted training and educational interventions to improve DHL in hypertensive patients.

Implications for the profession and/or patient care: Enhancing DHL levels through targeted interventions in patient care allows patients to effectively benefit from digital healthcare, achieve positive health outcomes and reduce disparities in care pathways.

Reporting method: This study adhered to the STROBE checklist for reporting.

Patient or public contribution: Patients were involved as the study population.

Protocol registration: Local Ethical Committee of the University Hospital Company of the Marche Region, Italy (protocol: 2023/279, date: 28/09/2023).

Keywords: blood pressure; digital health literacy; digital technology; hypertension; nursing; patient education; telehealth.

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. 2025 May 14;25(1):1776.
doi: 10.1186/s12889-025-23003-9.

Impact of functional, communicative, critical and distributed health literacy on self-management behaviors in chronic disease patients across socioeconomic groups

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Impact of functional, communicative, critical and distributed health literacy on self-management behaviors in chronic disease patients across socioeconomic groups

Shichen Chen et al. BMC Public Health. .

Abstract

Background: Effective self-management behaviors offer a promising pathway to address the health challenges faced by patients with chronic diseases. As a key factor influencing self-management behaviors, multidimensional health literacy has yet to be systematically studied in relation to its impact on patients with chronic diseases across different socioeconomic statuses.

Objective: To systematically investigate the influence of functional, communicative, critical, and distributed health literacy on self-management behaviors among patients with chronic diseases from different socioeconomic statuses.

Methods: A modified multidimensional health literacy and self-management behavior questionnaire was used to assess the health literacy and self-management behaviors of patients with chronic diseases. A total of 590 valid samples were obtained, and participants were divided into high and low socioeconomic status groups based on their socioeconomic background. Correlation analysis and multiple linear regression were conducted to explore the influence of various dimensions of health literacy on self-management behaviors across different socioeconomic statuses.

Results: After controlling for confounding variables, the communicative (β = 0.262, P < 0.01) and distributed (β = 0.343, P < 0.01) health literacy dimensions showed a significant positive impact on self-management behaviors in the low socioeconomic status group. In the high socioeconomic status group, critical (β = 0.253, P < 0.05) and distributed (β = 0.267, P < 0.01) health literacy demonstrated a significant positive effect on self-management behaviors. No significant impact was observed for functional health literacy in either group.

Conclusions: The study comprehensively reveals the distinct effects of different dimensions of health literacy on self-management behaviors among patients with chronic diseases from varying socioeconomic statuses. These findings provide a theoretical basis for developing strategies aimed at improving self-management behaviors through health literacy enhancement, particularly tailored to patients from different socioeconomic backgrounds.

Keywords: Chronic disease patients; Health equity; Multidimensional health literacy; Self-management behavior; Socioeconomic status.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: This study was approved by the Ethics Review Department of the Science and Technology Department of Wenzhou Medical University (approval number: 2024067). All participants provided written informed consent to participate in the study. Participation was voluntary. The study was conducted in accordance with the Declaration of Helsinki and relevant legislative guidelines. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

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Randomized Controlled Trial
. 2025 May 14:27:e65309.
doi: 10.2196/65309.

Effect of Gamification on Improved Adherence to Inhaled Medications in Chronic Obstructive Pulmonary Disease: Randomized Controlled Trial

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Free article
Randomized Controlled Trial

Effect of Gamification on Improved Adherence to Inhaled Medications in Chronic Obstructive Pulmonary Disease: Randomized Controlled Trial

Xiting Huang et al. J Med Internet Res. .
Free article

Abstract

Background: Inhaled medication is the preferred route of administration for patients with chronic obstructive pulmonary disease (COPD). The compliance rate of inhaled medication in patients with COPD is <50%, which increases the risk of acute exacerbations. Considering the complex steps of inhaled medication, improving inhaled medication compliance not only requires consistent medication frequency and medical advice but also an evaluation of whether the patient has mastered the inhaler technique to achieve the correct dose.

Objective: This study aimed to explore the effectiveness of an inhaled medication education program (Inhaling-Health website) based on the Fogg Behavior Model and gamification design on inhaled medication compliance and other health-related outcomes in patients with COPD.

Methods: In a randomized, 2-arm, concurrent parallel design, we enrolled 102 patients with COPD from respiratory medicine clinics at 2 hospitals in Zhejiang Province, China, between April and May 2023. Participants were randomly assigned to either the control group (51/102, 50%) or the experimental group (51/102, 50%). All participants completed the intervention, with 94 participants completing 6 months of follow-up. Two independent-sample 2-tailed t tests and the Mann-Whitney U test were used to analyze group differences, and generalized estimating equations were used to analyze repeated measurements.

Results: After the intervention, all outcome measures improved compared to baseline. The generalized estimating equation showed that, compared to the control group, the Inhaling-Health website led to a gradual improvement in total adherence-to-inhaler scores starting from 2 months after the intervention (median 51.00, IQR 49.00-52.25 vs median 50.00, IQR 47.00-51.00; Z=-2.014; P=.04). It had a separate positive effect on inhaler technique. In addition, the website was more effective in reducing the modified Medical Research Council score than routine inhaled medication education, starting from 4 months after intervention (median 1.00, IQR 1.00-2.00 vs median 1.00, IQR 0.00-2.00; Z=-2.260; P=.02). The website was also more effective than the conventional intervention in improving Chronic Obstructive Pulmonary Disease Knowledge Questionnaire scores, beginning at the end of the intervention (mean 6.14, SD 1.83 vs mean 7.06, SD 1.82; t1=-2.551; P=.01).

Conclusions: The gamified inhaled medication education program based on the Fogg Behavior Model can improve inhaled medication adherence, inhaler technique accuracy, health literacy, lung function, and health-related quality of life; help reduce the severity of dyspnea and COPD physical symptoms; and reduce the risk of acute exacerbations in patients with COPD. This study can provide a reference for inhaled medication education in patients with COPD.

Trial registration: China Clinical Trials Registry (ChiCTR) ChiCTR2300070213; https://www.chictr.org.cn/showprojEN.html?proj=194829.

Keywords: COPD; Fogg Behavior Model; chronic obstructive pulmonary disease; gamification; inhaled medication; medication adherence; randomized controlled trial.

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. 2025 May 14:1-14.
doi: 10.2989/17280583.2025.2465259. Online ahead of print.

Exploring mental health literacy and its intersection with help-seeking behaviours and gender in adolescents in the Western Cape

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Exploring mental health literacy and its intersection with help-seeking behaviours and gender in adolescents in the Western Cape

Michelle Scher et al. J Child Adolesc Ment Health. .

Abstract

Background: Adolescent mental illness contributes significantly to both the global and South African burden of mental health. Mental health literacy (MHL) promotes early recognition and intervention and consequently, determines mental health-promoting behaviours. We aimed to explore adolescent MHL and its intersection with help-seeking behaviour and gender in adolescents in the Western Cape.Method: The study instrument was a self-report survey/questionnaire. One hundred learners from public and independent schools in the Western Cape completed the survey.Results: There was a significant difference between first aid skills and help-seeking behaviours between the different genders. Specifically, girls were more prone to first aid skills and help-seeking behaviours than boys and other genders. Boys, on the other hand, were significantly more prone to using self-help strategies than girls and other genders. While gender differences were evident, these results are not sufficient to generalise to the larger population due to the limited sample.Conclusion: The results of this study are relevant to practitioners who wish to improve MHL and help-seeking behaviours among adolescents.

Keywords: Western Cape; adolescents; gender; help-seeking behaviour; mental health literacy (MHL).

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. 2025 May 14;317(1):758.
doi: 10.1007/s00403-025-04262-3.

Enhancing oncodermatology support: assessing patient utilization and satisfaction with educational resources for managing dermatologic toxicities of cancer treatment

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Enhancing oncodermatology support: assessing patient utilization and satisfaction with educational resources for managing dermatologic toxicities of cancer treatment

Sabrina Saeed et al. Arch Dermatol Res. .

Abstract

Dermatologic toxicities resulting from cancer treatments are common, debilitating, and can significantly impact a patient's quality of life. In some cases, these toxicities may require dose adjustments or even discontinuation of treatment. Timely management of dermatologic adverse events (DAEs) is crucial to improving patient outcomes, and educational resources are instrumental in empowering patients to recognize and manage these issues. This cross-sectional survey study aims to characterize patient utilization of and satisfaction with educational resources regarding dermatologic toxicities of cancer treatments. Findings indicate that while 77.5% (n = 110) of patients received information on managing dermatologic toxicities, a larger proportion (n = 123; 86.5%) experienced these side effects. Healthcare providers were the primary source of information (n = 102/110; 92.7%), followed by self-searching on the internet (n = 59/110; 53.6%), and social media (n = 43/110; 39.1%). Despite most patients receiving educational content, patients expressed low satisfaction with both the quality and quantity of information provided, with only 31.3% (n = 41) reporting satisfaction with the amount of information and 33.8% (n = 44) reporting satisfaction with its quality, highlighting a significant gap in resource effectiveness. Notably, patients reported the highest satisfaction with information provided by healthcare providers, suggesting that integrating comprehensive dermatologic education into oncologic care could improve patient satisfaction and outcomes.

Keywords: Dermatologic toxicity; Oncodermatology; Oncology; Patient education; Skin toxicity; Social media.

Conflict of interest statement

Declarations. Competing interests: Jonathan Leventhal received honoraria from Sanofi Regeneron and La Roche Posay for advisory boards; clinical trial research funding from OnQuality and Azitra, Inc; and royalties from UpToDate and Elsevier. Patient consent: Not applicable. IRB approval status: Study determined to be IRB exempt. Reprint requests: Jonathan Leventhal, jonathan.leventhal@yale.edu.

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. 2025 May 14.
doi: 10.1111/aogs.15123. Online ahead of print.

AI-driven simplification of surgical reports in gynecologic oncology: A potential tool for patient education

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AI-driven simplification of surgical reports in gynecologic oncology: A potential tool for patient education

Maximilian Riedel et al. Acta Obstet Gynecol Scand. .

Abstract

Introduction: The emergence of large language models heralds a new chapter in natural language processing, with immense potential for improving medical care and especially medical oncology. One recent and publicly available example is Generative Pretraining Transformer 4 (GPT-4). Our objective was to evaluate its ability to rephrase original surgical reports into simplified versions that are more comprehensible to patients. Specifically, we aimed to investigate and discuss the potential, limitations, and associated risks of using these simplified reports for patient education and information in gynecologic oncology.

Material and methods: We tasked GPT-4 with generating simplified versions from n = 20 original gynecologic surgical reports. Patients were provided with both their original report and the corresponding simplified version generated by GPT-4. Alongside these reports, patients received questionnaires designed to facilitate a comparative assessment between the original and simplified surgical reports. Furthermore, clinical experts evaluated the artificial intelligence (AI)-generated reports with regard to their accuracy and clinical quality.

Results: The simplified surgical reports generated by GPT-4 significantly improved our patients' understanding, particularly with regard to the surgical procedure, its outcome, and potential risks. However, despite the reports being more accessible and relevant, clinical experts highlighted concerns about their lack of medical precision.

Conclusions: Advanced language models like GPT-4 can transform unedited surgical reports to improve clarity about the procedure and its outcomes. It offers considerable promise for enhancing patient education. However, concerns about medical precision underscore the need for rigorous oversight to safely integrate AI into patient education. Over the medium term, AI-generated, simplified versions of these reports-and other medical records-could be effortlessly integrated into standard automated postoperative care and digital discharge systems.

Keywords: AI; GPT‐4; gynecology; large language models; patient education; surgery.

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. 2025 May 7;145(6).
doi: 10.4045/tidsskr.24.0336. Print 2025 May 13.

Self-management of INR - a focus group study

[Article in English, Norwegian]
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Free article

Self-management of INR - a focus group study

[Article in English, Norwegian]
Andrea Elisabeth Dahle-Andersen et al. Tidsskr Nor Laegeforen. .
Free article

Abstract

Background: Warfarin is a medication used in conditions with an increased risk of blood clots. Due to the potential for serious side effects, treatment must be closely monitored by measuring the International Normalised Ratio (INR). In some health trusts, Noklus (Norwegian Organization for Quality Improvement of Laboratory Examinations) offers training for patients in self-management of INR. The aim of this study was to explore Norwegian patients' experiences with self-management of INR and their motivations.

Material and method: In 2022, three focus group interviews were conducted at Nordland Hospital in Bodø, with a total of 16 individuals who performed self-management of INR. The interviews were audio-recorded, transcribed and analysed using systematic text condensation.

Results: Participants reported improved self-esteem and a sense of freedom after starting self-management of INR. Some expressed initial concerns about the increased responsibility for their own health, but they gradually developed a more relaxed attitude towards self-management. They also experienced reduced stress levels and gained increased knowledge about their own bodies. The training course enhanced participants' knowledge and confidence.

Interpretation: The study indicates that self-management of INR simplifies the daily life of patients and can have a positive impact on their quality of life.

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. 2025 Apr 25;14(9):2972.
doi: 10.3390/jcm14092972.

Health Literacy and Cognitive Disorders in Diabetic Patients

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Health Literacy and Cognitive Disorders in Diabetic Patients

Magdalena Florek-Łuszczki et al. J Clin Med. .

Abstract

Background/Objectives: Diabetes is a chronic metabolic disease affecting over 500 million adults worldwide, which is over 10% of the world's population. Diabetes is associated with a high risk of complications, including cognitive impairment of varying severity. Effective treatment of diabetes requires the patients not only to follow medical recommendations, but also to have appropriate health literacy (HL). The aim of the study was to determine the level of health literacy in diabetes patients, taking into account their cognitive functions. Methods: the study design consists of an anonymous survey involving 312 patients with type 1 and 2 diabetes, treated at the Diabetology Clinic of the Institute of Rural Health in Lublin, Poland. The survey was based on two standardized research tools, the 47-item European Health Literacy Questionnaire (EU-HLS-Q47) and the Mini-Mental State Examination (MMSE), and an original questionnaire focusing on the patients' health situation, metric questions, questions about self-assessment of knowledge, and educational needs. Results: The EU-HLS-Q47 and MMSE showed that diabetic patients mostly presented a sufficient level of health literacy. A limited level of health literacy was presented by 36.86% of the examined diabetic patients. A statistically significant relationship between the length of diabetes (in years) and the General Health Literacy, Health Care, and Health Promotion Indices was reported. The MMSE test showed that every third patient with diabetes had cognitive disorders of varying intensity. Conclusions: Patients with diabetes and their family members require coordinated care and targeted therapeutic education to prepare them for self-care and self-control so as to reduce the risk of complications.

Keywords: cognitive impairment; diabetes; health literacy.

Conflict of interest statement

The authors declare no conflicts of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.

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Randomized Controlled Trial
. 2025 May 3;17(9):1574.
doi: 10.3390/nu17091574.

Making Diet Management Easier: The Effects of Nudge-Based Dietary Education and Tableware in Individuals with Both T2DM and Overweight/Obesity: A 2 × 2 Cluster Randomized Controlled Trial

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Randomized Controlled Trial

Making Diet Management Easier: The Effects of Nudge-Based Dietary Education and Tableware in Individuals with Both T2DM and Overweight/Obesity: A 2 × 2 Cluster Randomized Controlled Trial

Tianxue Long et al. Nutrients. .

Abstract

Background/objectives: Traditional diet management for type 2 diabetes (T2DM) is often complex and effortful to sustain. Nudging offers low-effort and automatic approaches to dietary behaviour change yet remains underexplored in T2DM. This study evaluated the independent and combined 6-month effects of nudging education (NE) and nudging tableware (NT) on HbA1c, along with other secondary health outcomes, among adults with T2DM and overweight/obesity, compared to their non-nudge counterparts (control education, CE; control tableware, CT).

Methods: A 2 × 2 factorial cluster RCT was conducted in 12 primary healthcare settings in China (pre-registered as ChiCtr2100044471). Participants were randomly assigned to the nudging education group (NE + CT), the nudging tableware group (CE + NT), the combined group (NE + NT) or the full-control group (CE + CT) for 1 month. The primary outcome was HbA1c. Secondary outcomes included dietary behaviours, metabolic indicators, and psychological health. Generalized linear mixed models were used for analysis.

Results: A total of 284 participants (mean age, 52.28 years; 54.3% male) were randomly assigned and included in the analysis. After 6 months, NE and NT independently led to HbA1c reductions (-0.76%, p < 0.001; -0.33%, p = 0.042, vs. controls), with an additive but non-interactive effect when combined, resulting in a 1.04% reduction (p < 0.001) in the combined group. They also improved total calorie, macronutrient, and vegetable intake, FBG, plasma lipids, and BMI. NE additionally reduced diabetes distress and enhanced self-efficacy.

Conclusions: Both NE and NT improved dietary and metabolic outcomes without increasing the psychological burden. The combined group showed the greatest benefits. Findings highlighted the importance of considering automatic processes in diabetes management.

Keywords: dietary behaviour; dietary education; dual-process model; metabolic control; nudge; obesity; overweight; psychological health; tableware; type 2 diabetes.

Conflict of interest statement

The authors declare no conflicts of interest.

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. 2025 Apr 29;17(9):1515.
doi: 10.3390/nu17091515.

Food Literacy as an Instrument for Health Promotion Among Hospital Workers: The "ABCibi Project"

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Food Literacy as an Instrument for Health Promotion Among Hospital Workers: The "ABCibi Project"

Samar El Sherbiny et al. Nutrients. .

Abstract

Background: Health literacy (HL) promotes the achievement of skills and information useful to endorse health. Food Literacy (FL) is a subtype of HL related to the knowledge necessary to achieve a healthy diet. Methods: This pilot study aimed to assess and improve FL of hospital workers through a survey before and after an educational intervention consisting of nutrition courses, infographics, and updates to the canteen service. FL was evaluated with a questionnaire, and Kruskal-Wallis, Friedman and Wilcoxon test was performed to assess group differences. Results: Of 897 participants, 375 (T1) completed both surveys, while 522 completed only T0. A pairwise comparison stratified by role, age and education revealed a significant improvement in FL scores in the T1 group. Improvements were observed in the T1 group, with overall scores rising from 6.2 ± 2.7 to 6.9 ± 2.1 (p-value < 0.001). An upgrade was noted in healthcare workers (T0 = 6.5 ± 2.2 vs. T1 = 7 ± 2, p-value < 0.001), administrative workers (T0 = 5.5 ± 2.5 vs. T1 = 6.2 ± 2.4, p-value = 0.008), all age groups (T0 = 6.3 ± 2.4 vs. T1 = 6.8 ± 2, p-value = 0.03, T0 = 6.2 ± 2.3 vs. T1 = 6.7 ± 2.2, p-value = 0.02, T0 = 6.2 ± 2.3 vs. T1 = 7 ± 2, p-value = 0.003), low and high education (T0 = 5.7 ± 2.3 vs. T1 = 6.6 ± 2.1, p-value < 0.001, T0 = 6.6 ± 2.3 vs. T1 = 7.1 ± 2 p-value = 0.03). Conclusions: Our survey highlights the efficacy of a multifactorial intervention in enhancing FL and proves the importance of food health promotion within workplaces.

Keywords: food literacy; health literacy; health promotion; occupational health; public health.

Conflict of interest statement

The authors declare no conflicts of interest.

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. 2025 Apr 25;17(9):1438.
doi: 10.3390/nu17091438.

Protein Counting as an Educational Strategy to Optimize Low-Protein-Diet Adherence and Satisfaction in Stage 4 and 5 Chronic Kidney Disease Patients: A Pilot Study

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Protein Counting as an Educational Strategy to Optimize Low-Protein-Diet Adherence and Satisfaction in Stage 4 and 5 Chronic Kidney Disease Patients: A Pilot Study

Francesca K Martino et al. Nutrients. .

Abstract

Background/objectives: Educational support is a well-established strategy in diet management for chronic diseases. No study has reported the impact of protein counting in a low-protein diet for chronic kidney disease (CKD). We aimed to assess how a protein-counting educational program could enhance adherence and satisfaction in managing a low-protein diet in CKD patients with an eGFR below 20 mL/min/1.73 m2.

Methods: We conducted a prospective pilot study comparing adherence and satisfaction before and after an educational program, which included four group meetings and two individual meetings over six months. Diet adherence was assessed by estimating protein intake using 24 h urine urea excretion, while diet satisfaction was evaluated with the MDRD questionnaire.

Results: Twenty-four patients with a mean age of 63.9 years experienced improved diet adherence, with a significant reduction in protein intake (from 59.82 ± 15.57 g/day to 47.18 ± 13.7 g/day, p < 0.001) and a significant increase in overall diet satisfaction (from a median of 3.57 (3.1-4) to 4 (3.6-4.1), p = 0.001).

Conclusions: An educational program that includes protein counting assists CKD stage 4-5 patients in improving their diet adherence and increasing overall dietary satisfaction.

Keywords: adherence; chronic kidney disease; low-protein diet; protein counting; satisfaction.

Conflict of interest statement

The authors declare no conflicts of interest.

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. 2025 May 2;13(9):1048.
doi: 10.3390/healthcare13091048.

Health Literacy and Emotional Management in Patients on Renal Replacement Therapy: A Mixed-Method Study Protocol

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Health Literacy and Emotional Management in Patients on Renal Replacement Therapy: A Mixed-Method Study Protocol

Carmen González-Galán et al. Healthcare (Basel). .

Abstract

Background: Patients on renal replacement therapy (RRT) must adapt their lives to dialysis treatment, self-care routines, and medical restrictions, which can significantly impact their quality of life and emotional wellbeing. Additionally, limited health literacy hinders adherence to self-care practice, negatively affecting their health outcomes and treatment effectiveness. Given these challenges, this study aims to design and develop an action protocol that involves a change in the approach to health literacy and emotional management for patients on RRT, tailored to their specific needs, considering the different perspectives that influence the patient and their environment, including organizational, structural, care, and relational dimensions. Methods: The study will be based on the Ophelia (Optimizing Health Literacy and Access) methodology and consists of three phases over a three-year period (2025-2027): (a) a mixed design to explore health literacy level, coping strategies, adherence to self-care, and quality of life; (b) the development of the action protocol based on scientific evidence and the needs detected in this population; and (c) the validation of the protocol content by an expert panel made up of patients, professionals, and managers. Conclusions: The expected outcome is a clinically applicable protocol designed to improve health literacy and emotional management in patients undergoing RRT. This protocol will support healthcare administrators in structural and organizational planning, assist providers in delivering comprehensive care, enhance emotional support, and promote health literacy among patients. Ultimately, it aims to improve treatment adherence, health outcomes, and quality of life for this population.

Keywords: adherence; emotional management; health literacy; quality of life; renal replacement therapy.

Conflict of interest statement

The authors declare no conflicts of interest.

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. 2025 May 13;25(1):686.
doi: 10.1186/s12913-025-12796-5.

Economic outcomes of diabetes self-management education among older Medicare beneficiaries with diabetes

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Economic outcomes of diabetes self-management education among older Medicare beneficiaries with diabetes

Gang Lv et al. BMC Health Serv Res. .

Abstract

Background: Diabetes self-management education (DSME) has significant clinical benefits on diabetic glycemic control and reduction in the onset of complications. However, the economic benefits of DSME in older Medicare beneficiaries are not well known. The objective of this study is to examine the effect of DSME on different types of costs in older Medicare beneficiaries with diabetes.

Methods: This was a pooled cross-sectional study using the Medicare Current Beneficiary Survey (MCBS). The use of DSME was reported by survey respondents. Economic outcomes included total medical costs, total diabetes-related medical costs, total prescription costs, and total anti-diabetic prescription costs were measured based on Medicare claims and prescription drug events data from the perspective of the Medicare system. All costs were adjusted to 2012 U.S. dollars using the Consumer Price Index (CPI). Generalized linear models, with a log link and gamma distribution, were used to examine the effect of DSME on different costs.

Results: A total of 3,003 older Medicare beneficiaries with diabetes were included, among whom 35.50% (n = 1,066) had DSME. Individuals who did not have DSME had significantly higher total prescription costs than those who had DSME ($4,398.19 vs. $3,966.82, P =.0134). After adjusting for covariates, compared to those who did not have DSME, those who had DSME had 16.36% (95% CI: 9.69% to 22.54%) lower total medical costs and 12.83% (95% CI: 6.41% to 18.80%) lower total prescription costs.

Conclusion: This study found that DSME is associated with significantly lower spending in total medical and prescription costs for older Medicare beneficiaries. Given the economic benefits associated with DSME, different healthcare providers should further promote and increase the awareness of DSME to ensure sustained activities, enrollment, and patient retention in older Medicare beneficiaries with diabetes.

Keywords: Diabetes; Diabetes self-management education; Economic outcomes; Medicare; Older adults.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: The University of South Carolina Institutional Review Board approved this study. Because we used deidentified data from the Medicare Current Beneficiary Survey (MCBS), the University of South Carolina Institutional Review Board has waived the need for informed consent for this study. Specifically, the Office of Research Compliance, on behalf of the Institutional Review Board, approved the referenced study. This study was conducted in accordance with the Declaration of Helsinki. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

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Observational Study
. 2025 May 13;25(1):1753.
doi: 10.1186/s12889-025-23005-7.

Validity and reliability of Health Literacy for School-Aged Children (HLSAC) scale to understand the health literacy among adolescents in Bangladesh: An observational study

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Observational Study

Validity and reliability of Health Literacy for School-Aged Children (HLSAC) scale to understand the health literacy among adolescents in Bangladesh: An observational study

Popi Rani Bhowmik et al. BMC Public Health. .

Abstract

Background: Health Literacy (HL) is an effective determinant of health and health behaviors. The HL for School-Aged Children (HLSAC) scale has five components, and a 10-item was developed by Paakkari, 2016 in the Finnish language to measure the HL levels of adolescents. However, its validity and reliability were not tested among adolescents in the Bengali language. This study aimed to determine the validity and reliability of the HLSAC scale in the Bengali version among adolescents of secondary school children to evaluate their literacy status in Bangladesh.

Methods: A cross-sectional study was conducted among secondary school children in two different schools in Bangladesh. The schools were purposively selected, one from both rural and urban areas. The participants were students graded between 7 and 9 at the time of enrollment. The validity and reliability of the HLSAC scale were checked by confirmatory factor analysis, convergent validity, Cronbach's alpha, and test-retest reliability.

Results: The mean age of the participants was 13.5 years. The reliability of the HLSAC scale showed that Cronbach's alpha was 0.759. The confirmatory factor analysis model fit appears robust as the p-value was not significant (p = 0.137), 2 /df 1.263, RMSEA 0.029 and CFI = 0.982. The test-retest reliability of this scale was 0.388 (low). For the convergent validity, the Bengali version of the HLSAC scale was positively correlated with the General Self-Efficacy and Perceived Knowledge scales (r = 0.704, 0.618, respectively; all, p < 0.001).

Conclusion: Our study found that the HLSAC scale, Bengali version is valid and reliable for school-aged adolescents in Bangladesh. This research finding allows for a suitable HLSAC scale to measure the level of HL among adolescents in Bangladesh.

Keywords: Adolescents; Health Literacy; Health Literacy for School-Aged Children (HLSAC) scale; Reliability; Validity.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: This study was approved by the Institutional Review Board/Ethics Review Committee (IRB/ERC) of North South University, Bangladesh (reference number: 2023/OR-NSU/IRB/0707). This study is being conducted according to the Declaration of Helsinki. Written informed consent was obtained from all participants, and parents or legal guardians of any participant under the age of 16 to participate in this study. Confidentiality of individual information was maintained at all steps of the research. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

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. 2025 May 13.
doi: 10.1111/jop.13642. Online ahead of print.

Patient Education and Levels of Disease-Specific Information Needs Among Individuals With Oral Epithelial Dysplasia

Affiliations

Patient Education and Levels of Disease-Specific Information Needs Among Individuals With Oral Epithelial Dysplasia

Waleed Alamoudi et al. J Oral Pathol Med. .

Abstract

Background: Oral epithelial dysplasia (OED) is a histological diagnosis that carries an increased risk of the individual developing oral squamous cell carcinoma. We assessed the information needs (IN) and explored the sources of education used by individuals with OED using a validated OED-specific measurement.

Methods: A total of 102 adults with OED from the oral medicine clinic of a dental hospital in Central London were selected using convenience sampling. A cross-sectional survey was conducted in which participants completed the 33-item Oral Epithelial Dysplasia Informational Needs Questionnaire (ODIN-Q), which assessed IN and gathered perspectives on patient education.

Results: Approximately two-thirds of the participants (n = 66, 64%) reported meeting the IN, whereas the remaining participants (n = 36, 35%) did not. The mean and median total scores from the questionnaire were 2.43 (± 0.38) and 2.6, respectively, indicating a low sufficient level of IN. Most participants (n = 80, 78%) preferred one-on-one meetings as the primary mode of obtaining information, followed by written materials (n = 64, 62%), audiovisual resources (n = 24, 23%), and group discussions (n = 8, 0.7%).

Conclusions: Some topics were insufficiently met, necessitating additional educational efforts, such as risk factors and lifestyle modifications, physical and psychological impacts, awareness of potential complications, and seeking medical and psychological support. Sex and degree of dysplasia were associated with the levels of IN. These findings may guide future longitudinal research on OED IN assessment, support the creation of tailored educational tools, and facilitate further evaluation of the psychometric properties of the ODIN-Q.

Keywords: information needs; mouth precancer; oral dysplasia; patient education; quantitative study.

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. 2025 May 12:S1268-7731(25)00117-1.
doi: 10.1016/j.fas.2025.05.001. Online ahead of print.

Evaluation of ChatGPT responses to common patient questions on ankle fusion

Affiliations

Evaluation of ChatGPT responses to common patient questions on ankle fusion

Mahmut Kalem et al. Foot Ankle Surg. .

Abstract

Background: The study assessed the quality and readability of responses given by ChatGPT to common patient questions about ankle fusion.

Methods: Twenty-five frequently asked questions about ankle fusion were queried to ChatGPT 4.0 individually, and responses were assessed using the accuracy score developed by Mika et al. and the DISCERN tool. Readability was evaluated using the Flesch-Kincaid grade level, Gunning Fog, Coleman-Liau, and Simple Measure of Gobbledygook indexes.

Results: ChatGPT's responses were generally of acceptable quality, with a mean accuracy score of 2, indicating that the overall responses were satisfactory and required minimal clarification, along with a DISCERN score of 49.78, which is considered fair. However, the readability level was high, with a mean of 11.6 grade level.

Conclusions: ChatGPT showed promise as a resource for answering common patient questions about ankle fusion, providing mostly valid information. However, a high reading level was necessary to understand the response given.

Levels of evidence: N/A.

Keywords: Ankle arthritis; Ankle arthrodesis; Ankle fusion; Artificial intelligence; ChatGPT.

Conflict of interest statement

Declaration of Competing Interest The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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. 2025 May 13.
doi: 10.1097/CORR.0000000000003527. Online ahead of print.

Reply to the Letter to the Editor: Artificial Intelligence Shows Limited Success in Improving Readability Levels of Spanish-language Orthopaedic Patient Education Materials

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Reply to the Letter to the Editor: Artificial Intelligence Shows Limited Success in Improving Readability Levels of Spanish-language Orthopaedic Patient Education Materials

Rodnell Busigó Torres et al. Clin Orthop Relat Res. .
No abstract available

Conflict of interest statement

Each author certifies that there are no funding or commercial associations (consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article related to the author or any immediate family members. All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research® editors and board members are on file with the publication and can be viewed on request.

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. 2025 May 14:1-7.
doi: 10.3928/02793695-20250505-01. Online ahead of print.

Development of a Patient Education Pathway for a Psychiatric Nurse Consult Service

Development of a Patient Education Pathway for a Psychiatric Nurse Consult Service

Madeline Kuntz et al. J Psychosoc Nurs Ment Health Serv. .

Abstract

Purpose: The current quality improvement project aimed to improve functionality within a psychiatric consult liaison nurse (PCLN) service through implementation of an educational pathway.

Method: Pre- and postintervention qualitative interviews were conducted with eight PCLNs, and themes were generated via content analysis. Quantitative surveys were also conducted, and data were analyzed using means and standard deviations. Paired t tests were used to test for significance.

Results: Qualitative results identified five themes: Flexibility vs. Uncertainty, Ambiguity vs. Direction, Structured vs. Unstructured Education, Efficiency/Time Management, and Communication. Quantitative surveys indicated the intervention improved the consistency of the psychoeducation provided (p = 0.03) and enhanced the structure of the PCLN role (p = 0.04). The intervention did not significantly improve communication between PCLNs and medical-surgical nurses.

Conclusion: Qualitative findings showed that the educational pathway improved efficiency, time management, and communication, and quantitative findings showed it can help with consistency and structure to the role. Implementing an educational pathway for PCLNs is feasible and effective for health care systems. [Journal of Psychosocial Nursing and Mental Health Services, xx(xx), xx-xx.].

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. 2025 May 13;40(3):daaf046.
doi: 10.1093/heapro/daaf046.

Predicting health literacy in Brazil: a machine learning approach

Affiliations

Predicting health literacy in Brazil: a machine learning approach

Benjamin Miranda Tabak et al. Health Promot Int. .

Abstract

Health literacy is essential for promoting well-being and the ability to make informed decisions. We investigated the level of health literacy in Brazil and identified the predictive factors that influence it. Our data contribute to the international context, with a focus on countries in the Global South and, in particular, Latin America. By analyzing health literacy in Brazil, this study sheds light on the challenges faced by populations with similar socioeconomic backgrounds in low- and middle-income countries, where disparities in access to education and health services are widespread. In addition to descriptive analysis, we used the Random Forest machine learning algorithm, which uses bootstrap aggregation (bagging). To make the results interpretable, we implemented Shapley's Additive exPlanation values. The results show a predominance of problematic levels of health literacy among the population. The analysis reveals that factors such as medication use, dependence on the Unified Health System (Sistema Único de Saúde), and educational level are significant predictors of health literacy. The findings highlight the need for public policies aimed at reducing socioeconomic disparities and improving the public health system in order to promote better access to and understanding of health information.

Keywords: Brazil; Health Literacy Survey (HLS-EU-Q6); Random Forest; health literacy; machine learning; public health.

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. 2025 May 13:27:e63030.
doi: 10.2196/63030.

Analyzing Usage of the Metaverse by Associations of Patients With Prostate Cancer During the 2023 Blue Ribbon Campaign: Cross-Sectional Survey Study

Affiliations
Free article

Analyzing Usage of the Metaverse by Associations of Patients With Prostate Cancer During the 2023 Blue Ribbon Campaign: Cross-Sectional Survey Study

Jung Ki Jo et al. J Med Internet Res. .
Free article

Abstract

Background: It is important to explain early diagnosis and treatment plans to patients of prostate cancer due to the different stages that diagnosis is made at and the corresponding stage-specific treatment options, as well as the varying prognoses depending on the choices made. Although various studies have implemented metaverse-based interventions across diverse clinical settings for medical education, there is a lack of publications addressing the implementation and validation of patient education using this technology.

Objective: This study explored the potential of the metaverse as an educational and informational tool for prostate cancer. We measured and analyzed participants' satisfaction and perceptions following a metaverse-based prostate cancer awareness campaign. We also evaluated the feasibility and potential effectiveness of the metaverse as a platform for hosting a virtual patient association and delivering health education.

Methods: The study was conducted via a questionnaire administered from September 15 to October 20, 2023, during the Blue Ribbon Campaign organized by the Korean Urological Association and the Korean Society of Urological Oncology. The postevent questionnaire was designed to assess the effectiveness of using the metaverse to increase awareness of prostate cancer. A total of 119 participants, including patients, caregivers, and members of the general population, completed the survey within the metaverse space and assessed their satisfaction and perceived awareness using a 5-point Likert scale.

Results: The mean educational satisfaction score was 4.17 (SD 0.65), the mean psychological satisfaction score was 4.06 (SD 0.70), the mean overall satisfaction score was 4.12 (SD 0.72), and the mean awareness score was 4.09 (SD 0.72) out of a possible 5 points. Among responses rated 4 or higher ("agree" or "strongly agree"), 82.8% (394/476) were in the educational aspect, 76.6% (365/476) in psychological satisfaction, 81% (289/357) in overall satisfaction, and 80.4% (287/357) in awareness. Statistical analysis revealed significant differences in psychological (median 4.0, IQR 3.50-4.63, vs median 4.50, IQR 4.0-4.56) and overall (median 4.0, IQR 3.67-4.83, vs median 4.33, IQR 4.0-4.67) aspects between the general population group and patients and caregivers (median 4.0, IQR 3.33-4.33, vs median 4.67, IQR 4.0-4.67).

Conclusions: The findings suggest that the metaverse holds promise as a platform for health care education and patient support, offering accessible and engaging experiences for patients, caregivers, and members of the general population. Our approach demonstrated a positive influence on participants' satisfaction and perceived awareness, highlighting its potential to enhance health communication and patient engagement. Despite these encouraging results, limitations, such as the sample being skewed toward younger participants and reliance on self-reported data, underscore the need for more rigorous and multidimensional assessment strategies. Future studies should incorporate objective knowledge assessments, behavioral follow-ups, and qualitative methods to better evaluate the intervention's effectiveness. This study provides early evidence that metaverse-based interventions can support disease awareness and promote preventive health behaviors, contributing to the ongoing evolution of digital health education.

Keywords: Korean; awareness; cancer; cross-sectional study; digital health; effectiveness; healthcare; medical education; metaverse; morbidity; oncology; patient education; patient engagement; patient satisfaction; prostate cancer; prostatic neoplasm; questionnaire; self-help group; survey; technology; urologic malignancy; urology; virtual reality.

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. 2025 May 12:326:111-115.
doi: 10.3233/SHTI250249.

Is There Value Without Context? A Survey Evaluating How Laboratory Test Results Are Presented to Patients in Canada

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Is There Value Without Context? A Survey Evaluating How Laboratory Test Results Are Presented to Patients in Canada

Dana Nyholt et al. Stud Health Technol Inform. .

Abstract

Although direct reporting of laboratory test results to patients improves engagement and utilization of healthcare services, this assumes that results are presented in a manner that can be comprehended and acted upon by patients. To evaluate the practice of patient reporting across Canadian laboratories, a voluntary survey was distributed. 22 responses were received from laboratories and laboratory networks nationwide, representative of the range of Canadian laboratory and patient demographics. Despite the Connected Care for Canadians Act being passed in June 2024, one-third of respondents do not provide results to patients. Of those that do, results largely replicate physician reports and are heterogeneous between labs, with different strategies used to present data and flag abnormalities. A minority of labs suppress some testing from patient receipt, modify reports to improve patient comprehension, or provide graphs to support interpretation and trending. Laboratory professionals largely agreed that there are benefits in modifying reports to aid in patient comprehension but expressed concern that patient health literacy is currently in adequate. This may lead to increased anxiety, misinterpretation of results, follow-up questions, self-diagnosis, and undue stress until a healthcare provider could be consulted. Collaboration with patients and healthcare providers is necessary to develop guidelines on meaningful direct-to-patient reporting.

Keywords: Laboratory result visualization; health data access; patient health literacy; patient health portals.

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. 2025 May-Jun;33(3):e70041.
doi: 10.1111/wrr.70041.

How Successful Is AI in Developing Postsurgical Wound Care Education Material?

Affiliations

How Successful Is AI in Developing Postsurgical Wound Care Education Material?

Yeliz Sürme et al. Wound Repair Regen. 2025 May-Jun.

Abstract

ChatGPT can be used as an aid in education, research and clinical management. This study was conducted using the ChatGPT 4.0 program to develop artificial intelligence-supported wound care education material that can be read and understood by patients discharged after surgery. In this methodological study, while creating wound care education material, the education needs of the patients were determined first. Then, the education content was created in the ChatGPT 4 program. Expert opinion was taken for the clarity, applicability, accuracy and quality of the education content. The Turkish readability index of the education material was found to be 68.9 and easily understandable. The Automated Readability Index was found to be 9.29, the Simple Measure of Gobbledygook 7.89, the Flesch-Kincaid 8.07, the Flesch Reading Ease 59.0 and the Average Reading Level Consensus 9.99, which are frequently used in health literature. The PEMAT understandability and applicability score averages were determined 93.90 ± 6.11 (84-100) and 90.20 ± 8.66, respectively. The Global Quality Scale score average was found to be 4.40 ± 0.69. This study reveals that ChatGPT provides understandable, applicable, accurate and high-quality postoperative wound care education material.

Keywords: artificial intelligence; patient education; patient education material; surgery; wound care.

Conflict of interest statement

The authors declare no conflicts of interest.

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. 2025 Apr 10:31:2349.
doi: 10.4102/sajpsychiatry.v31i0.2349. eCollection 2025.

Mental health literacy among secondary school learners in Tshwane region 1: A quantitative study

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Mental health literacy among secondary school learners in Tshwane region 1: A quantitative study

Dumisile P Madlala et al. S Afr J Psychiatr. .

Abstract

Background: Mental health literacy (MHL) is one of the crucial factors in the prevention and maintenance of youth mental health. Despite this fact, there is limited research on MHL in this age group.

Aim: To determine the MHL in a sample of secondary schoolgoing learners.

Setting: Five schools in Tshwane, South Africa.

Methods: A quantitative cross-sectional study was done. Three fictive vignettes depicting individuals having symptoms of major depressive disorder (MDD), substance-induced psychotic disorder (SIPD) and social anxiety disorder (SAD) were presented to participants. The ability to recognise the disorder, knowledge of the best form of help to address the symptoms, and the ability to provide psychological first aid support were assessed. A comparison of MHL between township school learners and urban school learners was conducted. The association between MHL and demographic factors was also assessed.

Results: The ability to recognise symptoms and connect them to a particular disorder was high (80.71% for MDD, 61.96% for SIPD and 67.91% for SAD). Correct knowledge on who would best address the symptoms was 52.55% for MDD, 63.83% for SIPD and 23.86% for SAD with a sizable number choosing informal help for the cases of MDD and SAD. There was good psychological first aid knowledge for both MDD and SIPD cases but poor for SAD case.

Conclusion: Even though the results are promising regarding the recognition of all three disorders, there is still room for improving MHL in this group, especially in the areas of help-seeking and knowledge about anxiety disorders in general.

Contribution: The findings highlight key areas of focus during mental health awareness campaigns to learners.

Keywords: South Africa; Tshwane; learners mental health literacy; mental health literacy; school learners.

Conflict of interest statement

The authors declare that they have no financial or personal relationship(s) that may have inappropriately influenced them in writing this article.

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. 2025 May 8:20:1407-1417.
doi: 10.2147/COPD.S517564. eCollection 2025.

The Impact of Case Management on Elderly Patients with Chronic Obstructive Pulmonary Disease

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The Impact of Case Management on Elderly Patients with Chronic Obstructive Pulmonary Disease

Na Li et al. Int J Chron Obstruct Pulmon Dis. .

Abstract

Purpose: This study aims to investigate the effects of case management on elderly patients with chronic obstructive pulmonary disease (COPD) and compare changes in pulmonary function indicators, quality of life, dyspnea, and inhaled medication adherence before and after case management.

Patients and methods: A total of 199 elderly COPD patients were enrolled from Beijing Tsinghua Changgung Hospital between January 2020 and November 2023. We implemented case management programs including regular patient education, personalized interventions, continuous support systems, and timely feedback mechanisms, and subsequently collected patient data at 1, 3, 6, and 12 months after initiating case management.

Results: After one year of case management, pulmonary function indicators (FEV1/FVC, FEV1, FEV1%pred, MMEF75/25 and MMEF75/25%) in elderly patients with COPD showed significant improvement (P < 0.001). The CAT score decreased from 17.96±6.57 (mean ± standard deviation) to 11.80±6.50, and mMRC score decreased from 2.35±0.66 to 1.14±0.92 (p<0.001). Additionally, 77.9% (155/199) of patients were able to maintain their use of the inhaler for 1 year.

Conclusion: This study confirmed the significant role of case management in improving respiratory function, quality of life, and dyspnea in elderly patients with COPD. These findings not only provide a valuable reference for clinicians and patients, but also provide a strong foundation for further optimization of management strategies for elderly patients with COPD.

Keywords: adherence for inhaled therapies; case management; chronic obstructive pulmonary disease; elderly patients; respiratory function.

Conflict of interest statement

The authors report no conflicts of interest in this work.

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. 2025 May 8:19:1337-1350.
doi: 10.2147/PPA.S513375. eCollection 2025.

Mediating Effects of Health Literacy, Self-Efficacy, and Social Support on the Relationship Between Disease Knowledge and Patient Participation Behavior Among Chronic Ill Patients: A Cross-Sectional Study Based on the Capability-Opportunity-Motivation and Behavior (COM-B) Model

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Mediating Effects of Health Literacy, Self-Efficacy, and Social Support on the Relationship Between Disease Knowledge and Patient Participation Behavior Among Chronic Ill Patients: A Cross-Sectional Study Based on the Capability-Opportunity-Motivation and Behavior (COM-B) Model

Minjuan Wu et al. Patient Prefer Adherence. .

Abstract

Purpose: Patient participation is essential for improving patient safety and quality of care. It mainly refers to patients participating in their own healthcare through various ways, such as searching information on treatment options, engaging in decision-making, and communicating with healthcare professionals. This study aimed to investigate the relationships between disease knowledge, health literacy, self-efficacy, social support, and patient participation behavior in chronic ill patients based on the Capability-Opportunity-Motivation and Behavior (COM-B) model.

Methods: This cross-sectional survey, conducted from October 2023 to January 2024, involved 389 chronic ill patients from five clinical departments (cardiology, endocrinology, respiratory medicine, neurology, and geriatrics) at a tertiary hospital in Hangzhou, Zhejiang Province. Patients completed the health literacy management scale, general self-efficacy scale, core knowledge of chronic diseases questionnaire, social support rating scale, and patient participation scale. We used t-tests / ANOVA, Pearson's correlation coefficient, Fisher's z-test, linear regression, and mediation model to analyze data.

Results: The total effect of disease knowledge on patient participation behavior was significant (β = 0.496, p < 0.001), and the direct effect was also significant (β = 0.144, p < 0.001). Meanwhile, the relationship between disease knowledge and patient participation behavior was mediated by self-efficacy (β = 0.043, p < 0.001), health literacy (β = 0.027, p < 0.001), and social support (β = 0.193, p < 0.001), respectively.

Conclusion: This study proposed a conceptual model that includes the mediating effects of health literacy, self-efficacy, and social support, which helps clarify the underlying mechanisms between disease knowledge and patient participation behavior. Targeted interventions to increase disease knowledge, health literacy, self-efficacy, and social support can help chronic ill patients engage more actively in their own healthcare.

Keywords: chronic diseases; health literacy; patient participation; self-efficacy; social support.

Conflict of interest statement

The authors report no conflicts of interest in this work.

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. 2025 May 12;24(1):509.
doi: 10.1186/s12912-025-03118-5.

Bridging the gap: summative content analysis of understanding barriers in elderly patient education from nurses' perspectives

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Bridging the gap: summative content analysis of understanding barriers in elderly patient education from nurses' perspectives

Afshin Khazaei et al. BMC Nurs. .

Abstract

Background: One of the main tasks of nurses in providing health therapeutic services is patient education, an essential component of nursing care. This educative process is necessary for elderly patients with multiple and personalized needs. Hence, this study identified and prioritized the factors that hinder nurses from educating elderly patients admitted to teaching hospitals.

Methods: Data were collected through an electronic survey (Porsline) via summative content analysis. This study was conducted with nurses in teaching hospitals in Hamadan, western Iran, from December 2024 to January 2025. Seven hundred twenty-four nurses were recruited through convenience sampling to answer the following open-ended question: "In your opinion, what are the causes and factors that you when educating elderly patients in the hospital ward?"

Results: The analysis was organized into 12 main categories and 26 subcategories, which were ultimately reduced to six main themes, and their frequencies were calculated. The most frequent category was "staff training," which appeared 1,387 times, whereas the least frequent category was "lack of motivation," with 91 repetitions. Other categories were identified through data analysis on the basis of frequency and significance, including "hospital setting," "memory issues," "attention deficits," language and communication difficulties," sensory impairments," family involvement," peer support," mobility issues," pain and discomfort," anxiety and depression."

Conclusions: This study identified the main barriers preventing nurses from educating elderly patients in Iranian hospitals. Nurses can address these barriers by being more thorough in training, improving human resources, and upgrading relevant capacities and methods, leading to enhanced health literacy, self-care management, and improved quality of care overall for this population group. Organized community in-process support for multimorbidity patients is the key to strengthening self-care management. Implications of all the available evidence The results of this study have implications for practice. These findings may serve as a foundation for developing interventions and policies to address these barriers and enhance care for geriatric patients.

Clinical trial number: Not applicable.

Keywords: Elderly; Nursing; Patient education; Qualitative study.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: This study was approved by the Ethics Committee of Hamadan University of Medical Sciences (IR.UMSHA.REC.1403.601) and was conducted in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments [41]. Before participating in the survey, the participants were informed about the study’s objectives and methods, the confidentiality of their data, and their right to withdraw at any time without consequence. Each participant provided written informed consent. All study procedures adhered to the applicable guidelines and regulations. Consent for publication: The participants provided consent for their data to be published. Competing interests: The authors declare no competing interests.

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. 2025 May 12;25(1):690.
doi: 10.1186/s12909-025-07217-4.

Exploring the impact, challenges, and integration of podcasts in patient education: a systematic review

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Exploring the impact, challenges, and integration of podcasts in patient education: a systematic review

Saeed Khayat Kakhki et al. BMC Med Educ. .

Abstract

Background: Podcasts have become increasingly prominent as tools for health communication, offering flexible and accessible formats for patient education. While widely used in professional training, their role in supporting patient-centered learning remains underexplored.

Methods: This systematic review synthesized studies published from 2010 to 2024 concerning podcast use in patient education. Five databases-PubMed, Scopus, Web of Science, Google Scholar, and Embase-were searched using defined keywords. Studies were selected based on relevance to patient education through podcasts, and outcomes such as knowledge retention, comprehension, and engagement. Data extraction was performed independently by two reviewers. Quality assessment was conducted using the Cochrane Risk of Bias Tool, the Newcastle-Ottawa Scale, and the CASP checklist. A thematic synthesis approach was employed to analyze qualitative and quantitative findings.

Results: Of the twenty-one included studies, seven demonstrated improved patient knowledge retention, comprehension, and engagement through podcast use. Five studies emphasized accessibility and learner autonomy, highlighting the benefits of asynchronous and flexible delivery. Three studies explored the integration of podcasts with traditional teaching methods, showing positive outcomes when used as complementary tools. However, three studies identified challenges including content quality variability, limited production standards, and digital access disparities. Thematic synthesis categorized findings into four domains: educational effectiveness, integration with traditional education, accessibility and learner autonomy, and implementation challenges.

Conclusions: Podcasts represent a promising adjunct to patient education. Their effectiveness depends on thoughtful design, contextual relevance, and equitable delivery. Standardization, blended learning models, and ongoing evaluation are essential for maximizing their impact.

Clinical trial number: Not applicable.

Keywords: Health education; Media; Patient education; Podcast.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: Duo to study design Not applicable. Consent for publication: N/A. Competing interests: The authors declare no competing interests.

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Randomized Controlled Trial
. 2025 May 12;20(5):e0323608.
doi: 10.1371/journal.pone.0323608. eCollection 2025.

Study of the psychometric properties of the HLS-EU-12 questionnaire in rural Bangladesh

Affiliations
Randomized Controlled Trial

Study of the psychometric properties of the HLS-EU-12 questionnaire in rural Bangladesh

Fakir M Amirul Islam. PLoS One. .

Abstract

Objectives: Poorer health literacy leads to limited knowledge of diseases and lower adherence to medication. Several tools are available for measuring health literacy, including the HLS-EU-Q12 questionnaire. This study aimed to examine the psychometric properties of the HLS-EU-Q12 questionnaire using Rasch measurement theory to assess general health literacy among adults in rural Bangladesh.

Materials and methods: Baseline data was collected through a cluster randomized control trial (RCT) in the Narail district of Bangladesh from 1 December 2020 to 31 January 2021, involving 307 adults aged 30-75 with hypertension. The HLS-EU-Q12 questionnaire, which has 12 items, was validated using the Rasch measurement model and analyzed using RUMM2030. The analysis was focused on differential item functioning (DIF) across gender and age, targeting, multidimensionality, response dependency, and item categorization.

Results: The sample consisted of almost equal proportions of females (50.2%) and males (49.8%), and control (50.8%) and intervention participants (49.2%). Initial examination indicated that the tool had a poor overall fit with the Rasch model, shown by a significant item-trait interaction (χ2 = 100.5 df = 48, p < 0.001). The reliability, measured by person separation index (PSI), was 0.746, which was considered satisfactory. The overall item fit residual (IFR) (M = 0.236, SD = 1.318) and the person fit residuals (PFR) (M = -0.186, SD = 1.03) were within the acceptable range of SD ± 1.4. All items were found to have ordered thresholds, suggesting that respondents had no difficulty differentiating between response options on the 4-point Likert-type scale. Only item 12 ("Join a sports club or exercise class if you want to") had a fit residual value outside the acceptable range. Removing item 12 resulted in a good overall fit (χ2 = 60.35 df = 44, p = 0.05) and a slight improvement to the PSI (0.746 for 12 items vs.0.756 for 11 items). None of the items showed significant DIF for age and gender. Only two items showed residual correlation coefficient 0.20, indicating possible redundancy. The analysis demonstrated the scale's unidimensionality, as shown by the lower bound of a binomial 95% confidence interval (CI) for the observed proportion (5.2%) being within the 95% confidence limit.

Conclusion: The study demonstrated the potential effectiveness of the HLS-EU-Q12 as a tool for assessing health literacy among adults in Bangladesh. However, further study is needed to evaluate the tool across different populations, including an in-depth investigation of item 12 to determine its inclusion or removal.

Trial registration: ClinicalTrials.gov NCT04505150. Registered on 7 August 2020.

Conflict of interest statement

The authors have declared that no competing interests exist.

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. 2025 May 8;34(9):S10-S16.
doi: 10.12968/bjon.2024.0285.

A guide to the fundamental aspects of prostate cancer and the nurse's role

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A guide to the fundamental aspects of prostate cancer and the nurse's role

Barry Hill et al. Br J Nurs. .

Abstract

Prostate cancer remains a significant health concern, particularly among older men. This article provides an in-depth examination of prostate cancer, focusing on the critical role of nurses in managing this condition. It covers the pathophysiology, diagnosis and treatment options for prostate cancer, emphasising the importance of patient education, psychosocial support and holistic care. Through a detailed exploration of evidence-based practices, this article aims to enhance nurses' understanding of the subject and their ability to deliver comprehensive care to patients with prostate cancer, ultimately improving patient outcomes and quality of life.

Keywords: Holistic care; Nursing care; Patient education; Prostate cancer; Psychosocial support; Treatment management.

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. 2025;31(1):1-8.
doi: 10.5114/pedm.2025.148400.

Cross-sectional evaluation of people with type 1 diabetes participating in the GoPump Structured Diabetes Education Program during "Insulin Pump Weeks"

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Cross-sectional evaluation of people with type 1 diabetes participating in the GoPump Structured Diabetes Education Program during "Insulin Pump Weeks"

Marta Najmanowicz et al. Pediatr Endocrinol Diabetes Metab. 2025.

Abstract

Introduction: Despite advances in therapy, most persons with type 1 diabetes (PwT1Ds) do not achieve treatment goals. Education is fundamental to the care of PwT1Ds treated with continuous subcutaneous insulin infusion (CSII).

Aim of the study: To evaluate PwT1Ds treated with CSII and receiving in-hospital education and to identify factors associated with treatment effectiveness.

Material and methods: This cross-sectional study included adults with type 1 diabetes (T1D), who received diabetes education using the proprietary Structured Diabetes Education Program, GoPump, during "Insulin Pump Weeks" in 2022-2023. Metabolic control of diabetes was evaluated. Reports from personal insulin pumps, blood glucose meters, and continuous glucose monitoring (CGM) systems were assessed.

Results: Data from 107 individuals with a median age of 26.7 years (Q1-Q3: 19.0-30.8) were analysed, including 65 women (60.7%). The median duration of T1D was 13 years (Q1-Q3: 10.0-18.0), and the median duration of personal insulin pump use was 8 years (Q1-Q3: 5.0-12.0). The median body mass index was 23.9 kg/m². CGM was used by 52.3% of individuals. The median time in range (TIR) was 57.0% (Q1-Q3: 45.0-69.5%), and the median glycated haemoglobin (HbA1c) level was 7.9% (Q1-Q3: 6.8-8.5%). A positive correlation was found between age and TIR (rs = 0.42, p = 0.001). The use of temporary basal rate and dual-wave and square bolus features was positively correlated with TIR (rs = 0.34, p = 0.012 and rs = 0.31, p = 0.021, respectively) and inversely with time above range > 250 mg/dl (rs = -0.37, p = 0.007 and rs = -0.27, p = 0.045, respectively). Lower HbA1c levels were observed in individuals with a higher number of daily boluses (rs = -0.33, p = 0.001).

Conclusions: In the study cohort, older age, more frequent use of advanced insulin pump features, and a higher number of daily boluses were associated with better glycaemic control in adults with T1D.

Wstęp: Mimo postępów w leczeniu większość osób z cukrzycą typu 1 (PwT1Ds) nie osiąga celów terapeutycznych. Edukacja stanowi podstawę opieki nad PwT1Ds, leczonymi za pomocą ciągłego podskórnego wlewu insuliny (continuous subcutaneous insulin infusion – CSII).

Cel: Ocena PwT1Ds stosujących CSII, edukowanych w trakcie hospitalizacji, a także identyfikacja czynników powiązanych z efektywnością leczenia.

Materiał i metody: Do badania przekrojowego włączono dorosłe osoby z cukrzycą typu 1 (T1D) edukowane z wykorzystaniem autorskiego programu Strukturalnych Programów Edukacji Diabetologicznej GoPump w trakcie „Tygodni pompowych” w latach 2022–2023. Oceniano wyrównanie metaboliczne cukrzycy. Analizie poddano raporty z osobistych pomp insulinowych, glukometrów i systemów ciągłego monitorowania glikemii (continuous glucose monitoring – CGM).

Wyniki: Analizowano dane 107 pacjentów z medianą wieku 26,7 roku (Q1–Q3: 19,0–30,8), w tym 65 kobiet (60,7%). Mediana czasu trwania T1D wynosiła 13 lat (Q1–Q3: 10,0–18,0), a mediana czasu stosowania osobistych pomp insulinowych wynosiła 8 lat (Q1–Q3: 5,0–12,0). Mediana wskaźnika masy ciała wynosiła 23,9 kg/m2. CGM stosowano u 52,3% osób. Mediana czasu w zakresie docelowym (time in range [TIR]) wynosiła 57,0% (Q1–Q3: 45,0–69,5%), a mediana wartości hemoglobiny glikowanej (HbA1c) wynosiła 7,9% (Q1–Q3: 6,8–8,5%). Stwierdzono dodatnią korelację między wiekiem a TIR (rs = 0,42, p = 0,001). Korzystanie z funkcji bazy tymczasowej oraz bolusa złożonego i przedłużonego istotnie korelowało pozytywnie z TIR (odpowiednio rs = 0,34, p = 0,012 i rs = 0,31, p = 0,021) oraz negatywnie z czasem powyżej zakresu docelowego >250 mg/dl (odpowiednio rs = –0,37, p = 0,007 i rs = –0,27, p = 0,045). Wartości HbA1c były mniejsze u osób z większą liczbą bolusów na dzień (rs = –0,33, p = 0,001).

Wnioski: W badanej grupie starszy wiek, częstsze korzystanie z zaawansowanych funkcji pompy insulinowej oraz większa liczba bolusów wiążą się z lepszą kontrolą glikemii u dorosłych osób z T1D.

Keywords: continuous glucose monitoring; continuous subcutaneous insulin infusion; type 1 diabetes mellitus.; diabetes education.

Conflict of interest statement

non declared

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Review
. 2025 Jan 27:50:34.
doi: 10.11604/pamj.2025.50.34.45903. eCollection 2025.

Management of penile prosthesis complications: a case series and review of current surgical strategies

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Review

Management of penile prosthesis complications: a case series and review of current surgical strategies

Moussaab Rachid et al. Pan Afr Med J. .

Abstract

Penile prostheses offer a definitive solution for organic erectile dysfunction, particularly in cases where medical therapies are ineffective or contraindicated. Despite advancements in surgical techniques and infection-resistant materials, complications still arise. This article presents a case series of three patients experiencing different penile prosthesis complications, including severe penile pain, perineal infection, and prosthesis displacement. Management strategies included surgical removal and replacement of prostheses, administration of antibiotics, and careful post-operative monitoring. Key complications discussed include infections, erosion, mechanical malfunctions, and persistent pain. Effective management involves strict aseptic techniques, patient education, and prompt surgical intervention when necessary. This study underscores the importance of meticulous surgical practice and ongoing patient care to mitigate complications and improve outcomes for penile prosthesis recipients.

Keywords: Penile implants; inflatable penile prostheses; semirigid penile prostheses.

Conflict of interest statement

The authors declare no competing interests.

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. 2025 Apr 25:13:1514968.
doi: 10.3389/fpubh.2025.1514968. eCollection 2025.

A multidimensional analysis of older adults wellbeing and health literacy in Alentejo: a cross-sectional study

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A multidimensional analysis of older adults wellbeing and health literacy in Alentejo: a cross-sectional study

Rute Sadio et al. Front Public Health. .

Abstract

Introduction: The global increase in the older adults population which represents 22% the population in Portugal and is especially pronounced in the Alentejo region, posed noteworthy challenges. Social isolation, particularly in rural areas, requires policies that promote inclusion and wellbeing, such as social prescription. This study aimed to conduct a multidimensional assessment of the older adults individuals in Alentejo, evaluating quality of life, wellbeing, functionality, loneliness and health literacy.

Methods: A cross-sectional design was performed involving 344 participants aged 65 and over, residing in the Alentejo region. Validated scales and Questionnaires were used to assess sociodemographic characteristics, quality of life, wellbeing, functionality, loneliness and health literacy. Data were analyzed using SPSS software, employing descriptive and inferential statistics to identify significant patterns and relationships between variables.

Results: The sample consisted of 52% women, with an average age of 75.3 years (SD = 7.31; range = 65-96 years). Wellbeing, as measured by the WHO-5 index, was preserved with an average score of 53 (SD = 4.29). Loneliness was prevalent, with 50% of participants experiencing it, and the average score on the UCLA Loneliness Scale was 41.9 (SD = 5.59). Pain and anxiety were the most commonly reported issues according to the EQ-5D-3L, with 57.3% reporting pain/discomfort and 48.5% reporting anxiety/depression. Health literacy levels were low, with, only 6.4% exhibiting excellent literacy, while 45.0% had problematic or inadequate literacy.

Discussion: The findings suggest that while preserved, significant differences exist between men and women, as well as between rural and urban residents. Mobility, pain, and anxiety were the primary factors affecting Quality of life, particularly in rural areas. Low health literacy was identified as a barrier to autonomy and effective health management, emphasizing the need for tailored interventions to promote active and healthy aging.

Keywords: functionality; health literacy; loneliness; quality of life; wellbeing.

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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. 2025 May 5:18:1515-1526.
doi: 10.2147/RMHP.S514409. eCollection 2025.

Associations Between Health Literacy and Chronic Disease Prevalence Among Employees in Chinese Petroleum Companies: A Cross-Sectional Study

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Associations Between Health Literacy and Chronic Disease Prevalence Among Employees in Chinese Petroleum Companies: A Cross-Sectional Study

Huifen Ma et al. Risk Manag Healthc Policy. .

Abstract

Background: Employees in the petrochemical industry are exposed to numerous occupational hazards, contributing to a higher prevalence of chronic diseases. Health literacy, which reflects an individual's ability to access, understand, and use health information, is a critical factor in managing chronic diseases. However, its specific role in this workforce is not well understood.

Objective: This study investigates the associations between health literacy and the prevalence and number of chronic diseases among employees in a Chinese petrochemical company.

Methods: In March 2022, a cross-sectional survey collected 39,491 valid responses from employees of a large petrochemical company in Shandong Province, China. Health literacy was measured using the National Health Literacy Monitoring Questionnaire, while chronic disease prevalence and number were self-reported. Logistic and linear regression were used to examine associations between health literacy and chronic disease prevalence and count, respectively.

Results: Among respondents, 72.1% reported at least one chronic disease, and 53.9% were classified as having adequate health literacy. The domain of Health-Related Skills had the lowest qualification rate (46.4%), and the dimension of Chronic Disease Prevention and Control was the lowest-scoring dimension (33.0%). Overall health literacy was not significantly associated with chronic disease prevalence but was negatively associated with the number of chronic diseases (B = -0.05, 95% CI: -0.08 - -0.02, p < 0.001). Notably, higher literacy in Chronic Disease Prevention and Control was significantly associated with both reduced prevalence (OR = 0.95, 95% CI: 0.90-1.00, p = 0.034) and fewer chronic diseases (B = -0.01, 95% CI: -0.02-0.00, p = 0.004).

Conclusion: While overall health literacy was not significantly associated with chronic disease prevalence, it was negatively associated with the number of chronic diseases. Moreover, health literacy in Chronic Disease Prevention and Control showed significant associations with both lower prevalence and fewer chronic diseases.

Keywords: chronic disease; health literacy; health management; health promotion; petrochemical companies.

Conflict of interest statement

The authors report no conflicts of interest in this work.

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. 2025 Apr 10;17(4):e81993.
doi: 10.7759/cureus.81993. eCollection 2025 Apr.

Evaluating the Efficacy of ChatGPT vs. Google Gemini in Generating Patient Education Materials for GLP-1 Receptor Agonists (Semaglutide, Liraglutide, Tirzepatide): A Cross-Sectional Study

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Evaluating the Efficacy of ChatGPT vs. Google Gemini in Generating Patient Education Materials for GLP-1 Receptor Agonists (Semaglutide, Liraglutide, Tirzepatide): A Cross-Sectional Study

Nithin Karnan et al. Cureus. .

Abstract

Introduction: Diabetes management involves using various oral hypoglycemic agents, including new glucagon-like peptide-1 (GLP-1) receptor agonists like semaglutide, tirzepatide, and liraglutide. Artificial intelligence (AI) tools such as ChatGPT (OpenAI, San Francisco, United States) and Google Gemini (Google DeepMind, London, United Kingdom) provide an innovative approach to creating patient education materials, potentially enhancing the accessibility and understanding of medical information. Thus, the study aimed to compare the effectiveness of ChatGPT and Google Gemini in generating patient education brochures for semaglutide, tirzepatide, and liraglutide. Key criteria included readability, similarity, and reliability of the generated content.

Methodology: The cross-sectional study design was conducted in June 2024, involving data collection from ChatGPT-3.5 and Google Gemini. Each AI tool generated educational brochures for the three medications. The responses were evaluated using Flesch-Kincaid readability scores, Quillbot similarity analysis, and a modified DISCERN instrument for reliability assessment. Statistical analysis included univariate t-tests and Pearson's coefficient of correlation via RStudio v4.3.2 (Posit, Boston, United States).

Results: ChatGPT generated longer brochures with higher word counts compared to Google Gemini, which had better readability scores. Similarity analysis showed that Google Gemini's content had a higher percentage of overlap. Both AI tools demonstrated high reliability scores, with no significant difference between them.

Conclusions: Google Gemini provided more readable content, while ChatGPT produced slightly more detailed information. Both AI tools were effective in generating reliable patient education materials for GLP-1 receptor agonists. However, future research should incorporate more AI tools and updated versions for comprehensive analysis.

Keywords: artificial intelligence; chatgpt; diabetes; glp-1 receptor agonists; google gemini; liraglutide; patient education; readability analysis; semaglutide; tirzepatide.

Conflict of interest statement

Human subjects: All authors have confirmed that this study did not involve human participants or tissue. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

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. 2025 Apr 10;17(4):e82042.
doi: 10.7759/cureus.82042. eCollection 2025 Apr.

An Objective Analysis of the Quality and Readability of Online Information on Breast Implant Illness

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An Objective Analysis of the Quality and Readability of Online Information on Breast Implant Illness

Taylor Blount et al. Cureus. .

Abstract

Breast implant illness (BII) has emerged as a significant concern for patients with breast implants, characterized by a range of symptoms, including fatigue, cognitive impairment, and joint pain. The growing recognition of BII has prompted increased scientific investigation. However, despite the rising prevalence of breast augmentation procedures, there remains a lack of consensus within the medical community regarding the diagnosis, etiology, and treatment of BII. This study aimed to evaluate the readability of online resources pertaining to BII to determine their accessibility to the general population. A systematic internet search was conducted using three major search engines (Google, Bing, and Yahoo) with the query "breast implant illness." After excluding duplicates and paid content, 28 unique websites were analyzed using five established readability indices: Flesch-Kincaid Reading Ease Score (FRES), Gunning-Fog Index, Coleman-Liau Index, Simplified Measure of Gobbledygook (SMOG), and Automated Readability Index. The results revealed a considerable range in the readability of online materials related to BII. The average FRES was 50.4, categorizing the material as "fairly difficult" to read. The Gunning-Fog Score averaged 9.3, suggesting a 9th-grade education level for comfortable comprehension. The SMOG Index indicated a reading level appropriate for individuals with at least 13 years of education. The Coleman-Liau Index suggested a reading level corresponding to a 21-year-old, while the Automated Readability Index pointed to a high school freshman level. These findings highlight a significant disparity between the readability of available information and the recommended standards set by the American Medical Association and the National Institutes of Health, which propose that patient education materials should be written at a 6th-grade reading level or lower. The study's results are consistent with research on the readability of online health information in other domains, identifying a mismatch between the reading level of the general public and the complexity of available health information. The importance of readability in online health information cannot be overstressed, particularly in the context of BII, where decisions may include elective surgery with inherent risks. The study calls for the development and implementation of standardized guidelines for creating online health materials that are accessible to a diverse audience. This includes simplifying language, using clear formatting, and incorporating visual aids to enhance comprehension.

Keywords: breast implant illness; explantation surgery; flesch-kincaid; google; health literacy; online patient education; readability measures.

Conflict of interest statement

Human subjects: All authors have confirmed that this study did not involve human participants or tissue. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

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Meal-plate Method: Hemoglobin A1c Levels and Dietary Behavior Among Hispanics with Diabetes and Varying Levels of Acculturation Over Three Months

Bharat Gautam et al. J Health Care Poor Underserved. 2025.

Abstract

Objective: We studied education with the meal-plate method among Hispanics with uncontrolled diabetes and its impact on hemoglobin A1c (HbA1c) and dietary behaviors over three months.

Methods: Retrospective study of 102 Hispanics with HbA1c of eight percent or greater. Patients received physician-led education about the meal-plate method. Acculturation measures were the Short Acculturation Scale for Hispanics (SASH) and years lived in the United States. HbA1c and dietary behaviors were recorded at baseline and at three-month follow-up.

Results: Education with the meal-plate method was associated with lower HbA1c and improved dietary behavior of less juice-drinking and less cake/pastry/cookie-eating. Media acculturation on SASH was positively associated with appropriate juice-drinking at baseline. Years lived in the United States was positively associated with appropriate juice-drinking at follow-up.

Conclusions: Meal-plate method education, even if delivered by a solo clinician outside of an interdisciplinary program, can reduce HbA1c levels in people who are Hispanic.

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. 2025 May 11;12(1):e002799.
doi: 10.1136/bmjresp-2024-002799.

Cross-sectional study of preventive treatment for students with latent tuberculosis infection in Shanghai, China

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Cross-sectional study of preventive treatment for students with latent tuberculosis infection in Shanghai, China

Xiao Xiao et al. BMJ Open Respir Res. .

Abstract

Introduction: Tuberculosis preventive treatment (TPT) has been initiated systematically in Shanghai supported by a public health project. This study aimed to evaluate the acceptance of TPT, identify the factors related to its refusal, and find an optimal way to promote TPT among student tuberculosis (TB) contacts.

Methods: We screened contacts of the TB index case from a TB outbreak on campus. A two-step approach of first conducting a lecture of TB health literacy, followed by one-on-one TPT consultations was used to mobilise TPT among students with latent TB infection (LTBI). A semistructured questionnaire was designed between the lecture and the one-on-one TPT consultations, covering general demographic information, awareness of core TB knowledge and willingness to accept TPT, along with the reasons for refusal. Logistic regression analysis was used to identify the risk factors for refusing TPT.

Results: A total of 52 contacts were identified with LTBI. After the lecture on TB health literacy, their scores on the core TB knowledge was 14.0±2.3. Students had a poor awareness rate of TB knowledge in the part of TB treatment and policy (70.2%) and Mycobacterium tuberculosis infection preventive measures and LTBI (67.3%) compared with the average rate (84.3%). The acceptance rate of TPT reached 42.3% at the end of the two-step promotion. The main reasons for refusing TPT included: (1) the duration for TPT was too long and follow-up management was too cumbersome; (2) the confidence in their own immunity and belief in their low risk of TB and (3) the fear of side effects of TPT.

Conclusions: The two-step approach of first conducting a lecture of TB health literacy, followed by one-on-one TPT consultations, is effective for mobilising TPT. To further implement TPT, we recommend making the scientific popularisation for LTBI in a more easy-to-understand way and optimising the management of TPT.

Keywords: Infection Control; Tuberculosis.

Conflict of interest statement

Competing interests: None declared.

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. 2025 May 7:123:110491.
doi: 10.1016/j.clinimag.2025.110491. Online ahead of print.

Comparative analysis of interventional radiology awareness: insights from Turkey, the USA, and Europe using Google Trends data

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Comparative analysis of interventional radiology awareness: insights from Turkey, the USA, and Europe using Google Trends data

Ali Dablan et al. Clin Imaging. .

Abstract

Purpose: To evaluate public awareness of Interventional Radiology (IR) by analyzing internet search trends across Turkey, the United States (USA), and major European countries (2004-2024), and assess the quality of online IR educational resources.

Materials and methods: Google Trends data were analyzed for IR-related terms in five countries. Relative Search Volume (RSV) trends and growth rates were calculated. Top 10 IR-related websites in Turkish were evaluated using DISCERN and Flesch-Kincaid readability tools. Statistical significance was assessed using time series analysis (p < 0.05).

Results: The USA showed highest overall IR awareness (RSV:88), while Turkey demonstrated fastest growth (p < 0.001). European countries showed moderate but significant growth in IR-related searches. Procedure-specific searches (ablation, thrombectomy) increased significantly in Turkey post-2014 (p < 0.001). Online IR educational content in Turkish showed limited accessibility (mean Flesch-Kincaid score: 11.2 ± 1.4).

Conclusion: Significant regional disparities exist in IR awareness, with established presence in the USA contrasting with rapid growth in Turkey and moderate growth in Europe. Limited accessibility of educational resources, particularly in developing regions, suggests need for targeted interventions to improve IR awareness and enhance adoption of minimally invasive procedures.

Keywords: Awareness; Education; IR; Internet; Outreach; Radiography; Trends.

Conflict of interest statement

Declaration of competing interest The authors declare no conflict of interest.

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. 2025 May 9:183:109393.
doi: 10.1016/j.surg.2025.109393. Online ahead of print.

A literature review on the role of artificial intelligence-based chatbots in patient education in colorectal surgery

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Free article
Review

A literature review on the role of artificial intelligence-based chatbots in patient education in colorectal surgery

Laura Garcia Garcia et al. Surgery. .
Free article

Abstract

Introduction: Artificial intelligence-based chatbots are becoming increasingly used in patient education, in the realm of colorectal diseases. Perhaps, not surprisingly, concerns about the appropriateness of chatbot answers have been raised by healthcare professionals. Numerous studies have explored the utility and accuracy of chatbots in providing information in several clinical disciplines. This review aimed to summarize the findings of published studies, highlighting the strengths and limitations of chatbots used in medical education for colorectal surgery.

Methods: We searched MEDLINE via PubMed and Scopus in February 2025 for original articles evaluating artificial intelligence-based chatbots in patient education related to colorectal surgery, categorizing them into 3 groups: colorectal cancer, inflammatory bowel diseases, and other colorectal conditions.

Results: We identified 15 studies, 9 assessed chatbot utility in patient education in colorectal cancer, 4 assessed their utility in inflammatory bowel diseases, 1 involved benign anal conditions, and another involved intestinal stomas. Our findings indicated that chatbots, particularly ChatGPT, can improve patient education by providing accessible information on common questions. However, we also identified several limitations of the ability of chatbots to address complex medical issues which underscored that these tools may complement rather than replace professional medical guidance.

Conclusion: Chatbots may be useful for patient education related to simple and basic information, but not in complex and patient-specific settings. Future research should focus on refining chatbot algorithms to enhance the accuracy and depth of their responses, ensuring they effectively support patient education while maintaining the crucial role of healthcare providers.

Conflict of interest statement

Conflict of Interest/Disclosure Dr Wexner is a consultant for ActivSurgical, Arthrex, Baxter, Becton, Dickinson and Co, Glaxo Smith Kline, Intuitive Surgical, OstomyCure, Takeda, and Virtual Ports; has consulting agreements with stock options for consulting with GI View, OstomyCure, and Virtual Ports; is a member of the Data Safety Monitoring Board of JSR/WCG/ACI (chair) and Polypoid (chair); and receives royalties from Intuitive Surgical, Karl Storz Endoscopy America Inc, and Unique Surgical Solutions, LLC. Dr Emile is a consultant for Becton, Dickinson and Co. None of the other authors report any conflicts of interest.

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. 2025 May 9:S0363-5023(25)00163-7.
doi: 10.1016/j.jhsa.2025.03.022. Online ahead of print.

Evaluating the Association Between Health Literacy and Patient-Reported Outcome Measures After Distal Radius Fracture

Collaborators, Affiliations

Evaluating the Association Between Health Literacy and Patient-Reported Outcome Measures After Distal Radius Fracture

Katherine R Miclau et al. J Hand Surg Am. .

Abstract

Purpose: Patient-reported outcome measures (PROMs) are used to assess patients' outcomes during the treatment of distal radius fractures (DRFs). Limited health literacy is linked to poorer health outcomes. We asked whether limited health literacy is associated with PROM scores in patients with a DRF.

Methods: This cross-sectional study enrolled adults ≥18 years of age with an isolated DRF from two urban hospitals within 6 weeks of injury or surgery. Participants completed a demographics survey, brief health literacy screen, and three PROMs: Quick Disabilities of Arm, Shoulder, and Hand (QuickDASH); Patient-Reported Outcome Measurement Information System (PROMIS) Upper Extremity v2.0 Short Form-7a (PROMIS-UE); and Numeric Rating Scale (NRS). Associations between social determinants of health (SDOH) factors (health literacy, income, education, and preferred language) and PROMs were assessed using multivariable linear regressions. Propensity score analyses to control for confounding and postmatching regressions were conducted.

Results: Sixty-five patients participated in this study. In this sample, the mean age was 54 years, 65% were women, 26% had limited health literacy, 46% had public insurance, 18% completed at most a high school education, and 23% preferred a language other than English (PLOE). In multivariable analyses, limited health literacy and PLOE were associated with worse PROMIS-UE, and low income was associated with worse QuickDASH and NRS; associations between health literacy and QuickDASH and NRS were not statistically significant. Propensity score analyses indicated that all SDOH variables had confounding effects on associations between health literacy and PROMs. The postmatching regression analysis demonstrated that PLOE was associated with worse PROMIS-UE, and low income and PLOE with worse QuickDASH and NRS scores; limited health literacy was not significantly associated with any PROMs.

Conclusions: Low income and PLOE were significant predictors of worse PROM scores. After adjusting for other SDOH variables, limited health literacy was not significantly associated with PROM scores. These findings underscore the importance of recognizing and addressing the multiple interconnected SDOH aspects associated with PROM scores.

Type of study/level of evidence: Prognosis IV.

Keywords: Distal radius fracture; health literacy; income; language; patient-reported outcomes.

Conflict of interest statement

Conflicts of Interest No benefits in any form have been received or will be received related directly to this article.

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. 2025 May 10;25(1):673.
doi: 10.1186/s12913-025-12845-z.

Opportunities and challenges of social media for oral health literacy improvement: a qualitative investigation based on Iranian dentists' perspectives

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Opportunities and challenges of social media for oral health literacy improvement: a qualitative investigation based on Iranian dentists' perspectives

Hossein Ghalavand et al. BMC Health Serv Res. .

Abstract

Background: Despite the possible impacts of social media on oral health literacy, the specific challenges and opportunities in this particular setting remain underexplored. The current research objective was identify the opportunities and challenges of social media for oral health literacy based on Iranian dentists' perspectives.

Methods: In the current qualitative investigation, a semi-structured interview was conducted with 24 dentists utilizing a purposive snowball sampling method. The analysis of the data was performed using thematic analysis in the MAXQDA 10 software.

Results: The analysis of the interview data led to recognition of six main themes and a total of 16 sub-themes. The three main themes identified as opportunities for using social media for oral health literacy include facilitating accessibility, popularizing, and supporting usability. Three identified challenges for oral health literacy include quality issues, incomplete understandability, and create bias in usability for oral health information. Social media platforms present unique opportunities for enhancing information accessibility through increasing information encountering, interactive question-answering, and communication empowerment. Providing opportunities for simplifying information, promoting the prevention of oral health diseases, and clarifying information claims are social media facilitate roles that can effectively make information more understandable. Moreover, social media platforms facilitate the use of oral health information by supporting decision-making, dental counseling presentations, and experience sharing. Misinformation, the complexity of information quality evaluation and privacy, and ethical and security concerns are significant social media challenges for oral information accessibility. Insufficent published information and creating fear by reading health information (cyberchondria) are social media challenges that affect the understandability of information. Ignoring content disclaimers and misleading advertising are two challenges within social media that hinder the usability of oral health information.

Conclusion: Social media acts as a dual-faceted method for oral health literacy, providing both opportunities and challenges. Confronting the obstacles associated with social media demands the creation of solutions that strengthen their positive attributes.

Keywords: Dentists; Health literacy; Oral health; Social media; Storytelling.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: This study was conducted in accordance with the ethical principles set forth in the Declaration of Helsinki. The research protocol was reviewed and approved by the Ethics Committee in Biomedical Research at Abadan University of Medical Sciences (Ethical code: IR.ABADANUMS.REC.1403.030). During the preliminary meeting, consent for participation in the study was acquired verbally from the individuals before the interviews began. The consent that was obtained from all of the participants was informed by ethics committee. Should participants have inquiries or issues regarding their rights, they are encouraged to reach out to the Abadan University of Medical Sciences Institutional Review Board via email at research@abadanums.ac.ir. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

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. 2025 May 9;26(1):232.
doi: 10.1186/s12882-025-04153-9.

Clinical and financial impacts of nursing education programs on recurrent urinary tract infections after kidney transplant: a cohort study

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Clinical and financial impacts of nursing education programs on recurrent urinary tract infections after kidney transplant: a cohort study

Hany M El Hennawy et al. BMC Nephrol. .

Abstract

Background: Urinary tract infections (UTIs) are the most prevalent infections among kidney transplant recipients, with recurrent cases imposing a significant financial burden due to increased hospitalizations and treatment costs.

Objective: This study aims to investigate the incidence of recurrent UTIs and evaluate the financial impact of a comprehensive nursing education initiative.

Methods: A retrospective cohort study was conducted with kidney transplant patients, divided into two groups: a control group prior to the intervention and a study group following the implementation of the education program. The intervention consisted of weekly training sessions focusing on infection prevention, catheter care, and hygiene. Patient outcomes were monitored for one year post-transplant, with a focus on UTI rates, patient adherence, knowledge, and healthcare costs.

Results: The nursing education program resulted in a 26% reduction in UTI incidence and decreased average hospital stays from 8 days to 4 days. Healthcare costs per admission fell from $10,000 to $6,000, leading to total savings of $700,000 based on 175 admissions. The program resulted in a net saving of $650,000. Additionally, significant improvements were observed in patient knowledge, satisfaction, and compliance.

Conclusions: Nursing education on UTI prevention for kidney transplant patients effectively enhances clinical outcomes and reduces healthcare costs. These findings underscore the importance of integrating structured education programs into transplant care protocols to achieve sustainable health and economic benefits.

Clinical trial number: Not Applicable.

Keywords: Kidney transplant; Nursing; Patient education; Recurrent utis.

Conflict of interest statement

Declarations. Ethical approval and consent to participate: The local ethical committee approved the study (Armed Forces Hospitals Southern Region: AFHSRMREC/SURGERY, SECTION OF TRANSPLANTATION/746), and all participants gave informed consent to participate. This study was conducted according to the principles of the Declaration of Helsinki. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

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Review
. 2025 Jun;60(2):229-241.
doi: 10.1016/j.cnur.2024.12.008. Epub 2025 Jan 24.

The Parallels, Pearls, and Perils of Health and Genomic Literacy

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Review

The Parallels, Pearls, and Perils of Health and Genomic Literacy

Rebecca Kronk et al. Nurs Clin North Am. 2025 Jun.

Abstract

Considering the rapid evolution of -omics science and the ever-changing world of precision health care, nurses must seek opportunities to improve their genomic literacy. The parallels of health literacy and genomic literacy provide both pearls and perils. Knowing that low health literacy is associated with low utilization of health care services, we must prevent the same trajectory with genomic literacy. The recognition of health literacy and genomic literacy in Healthy People has the potential to yield better outcomes for all groups. Nurse champions are needed to generate and adopt policies that guide the integration of genomics into practice and education.

Keywords: Competency; Genetic literacy; Genomic literacy; Health literacy.

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. 2025 May 9:17:e59806.
doi: 10.2196/59806.

A Brief Video-Based Intervention to Improve Digital Health Literacy for Individuals With Bipolar Disorder: Intervention Development and Results of a Single-Arm Quantitative Pilot Study

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Free article

A Brief Video-Based Intervention to Improve Digital Health Literacy for Individuals With Bipolar Disorder: Intervention Development and Results of a Single-Arm Quantitative Pilot Study

Emma Morton et al. J Particip Med. .
Free article

Abstract

Background: Smartphone apps can improve access to bipolar disorder (BD) care by delivering elements of effective psychological interventions, thereby promoting quality of life and reducing relapse risk and mood instability in BD. While many people with BD are interested in using publicly available mental health smartphone apps, without guidance, they risk selecting apps that are unsafe or ineffective.

Objective: This study aimed to co-design a brief educational video on identifying appropriate mental health apps and to evaluate the acceptability and impact of this video among individuals with BD.

Methods: Individuals with lived experience of BD, including 2 peer researchers and members of 2 advisory groups (n=4 and n=7), were consulted to develop a video with information on selecting safe, effective, and engaging mental health apps for BD. Video acceptability and impact on self-reported digital health literacy (including both general eHealth literacy and more specific mobile health literacy) were evaluated via a web-based survey, including both a validated measure and complementary items developed by the research team.

Results: In total, 42 individuals with BD completed the evaluation survey (n=29, 69% women, mean age 38.6, SD 12.0 years). Digital health literacy, measured using the self-report eHealth Literacy Scale, significantly improved after viewing the video (pre: mean 32.40, SD 4.87 and post: mean 33.57, SD 4.67; t41=-3.236; P=.002; d=-0.50). Feedback supported the acceptability of the video content and format. Self-report items developed by the study team to assess mobile health literacy showed that individuals felt better able to determine which apps would protect their data (P=.004) and to ask their health care provider for support in choosing apps (P<.001) after watching the video.

Conclusions: This study found preliminary evidence that an educational video can help people with BD improve their ability to identify, apply, and evaluate the quality of digital health resources. The video and a supplementary web-based educational module are freely available for implementation in health care settings and have the potential to be a cost-effective and accessible resource for clinicians to support patients with BD to navigate the public app marketplace in support of their self-management goals.

Keywords: acceptability; apps; bipolar; bipolar disorder; digital health literacy; effectiveness; intervention; mHealth; mental health; mental health apps; mood instability; patient education; psychological; quality of life; self-management; single-arm pilot trial; smartphone apps; video-based intervention.

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. 2025 May 9:14:e71849.
doi: 10.2196/71849.

Telenursing Health Education and Lifestyle Modification Among Patients With Diabetes in Bangladesh: Protocol for a Pilot Study With a Quasi-experimental Pre- and Postintervention Design

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Free article

Telenursing Health Education and Lifestyle Modification Among Patients With Diabetes in Bangladesh: Protocol for a Pilot Study With a Quasi-experimental Pre- and Postintervention Design

Michiko Moriyama et al. JMIR Res Protoc. .
Free article

Abstract

Background: The global burden of chronic diseases is increasing and becoming a public health issue throughout the world. The use of telenursing is increasing significantly during and after the COVID-19 pandemic to treat and prevent chronic diseases. Telenursing is growing in many countries to reduce health care costs, increase the number of aging and chronically ill populations, and increase health care coverage to distant, rural, small, or sporadically populated regions. Among its many benefits, telenursing may help to solve increasing shortages of nurses, reduce distances, save travel time, and keep patients out of the hospital.

Objective: The objective of this study is to apply the self-management telenursing program and telenursing system developed by the researchers to Bangladesh and to evaluate its feasibility and efficacy (improved diabetes control in participants).

Methods: This is a pilot, quasi-experimental pre- and post-intervention study. Diabetes patients who will attend the Grameen Primary Health Centers (PHCs) in Bangladesh will be enrolled between September 2024 and August 2025. We include patients who have been diagnosed with type 2 diabetes, both sexes, ages 18-75 years old, all types of treatment, willing to participate and give us consent. We exclude patients who have been diagnosed with gestational diabetes, diabetes as a secondary cause, complication of chronic kidney disease (CKD) stage 5, Hemoglobin A1c (HbA1c) is less than 7% for the past 1 year with CKD stage 1 or 2, no complications or complications with good control, having enough knowledge (had education before) and implemented good practice regarding diabetes management assessed by the research nurses, and disabled persons who need other person's support for daily living. The sample size was calculated and found 70. Written informed consent will be obtained from all the participants. The study protocol got approval from the National Research Ethics Committee of the Bangladesh Medical Research Council (BMRC/NREC/2022-2025/336) on September 08, 2024. The outcome of this study is to evaluate the effects of telenursing intervention by controlling HbA1c.

Results: The project was funded in 2024. The enrollment of the participants started on October 26, 2024, and the required sample (n=70) enrollment was completed in February 2025. Data analysis will be started after completion of data collection and results will be expected to be submitted for publication in 2026.

Conclusions: Diabetic patients will acquire disease-specific management skills. Setting and monitoring goals ensures the continuation of the desired behavior and gives the patients control over their lifestyle. After developing self-management skills, patients assess their lab data and lifestyles including diet, and understand their condition so that they can work with their physiological data by acquiring knowledge of both the disease and self-care. By making self-supported decisions, the patients will be able to manage their diet, exercise, and medication.

Trial registration: ClinicalTrials.gov NCT06632652; https://clinicaltrials.gov/study/NCT06632652.

International registered report identifier (irrid): DERR1-10.2196/71849.

Keywords: Bangladesh; diabetic patients; health education; lifestyle modification; telenursing.

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. 2025 May 5:13:e19382.
doi: 10.7717/peerj.19382. eCollection 2025.

From grit to flourishing: physical literacy's mediating role in enhancing well-being among college students with obesity

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From grit to flourishing: physical literacy's mediating role in enhancing well-being among college students with obesity

Xingyu Liu et al. PeerJ. .

Abstract

Objective: To investigate whether physical literacy mediates the relationship between grit and well-being among college students with obesity.

Methods: A total of 385 students with obesity were recruited. Participants completed validated questionnaires measuring grit, physical literacy, and well-being. Mediation analyses were performed to estimate indirect effects and generate bias-corrected 95% confidence intervals (CI).

Results: Grit was positively associated with physical literacy, and physical literacy was positively associated with well-being. Physical literacy partially mediated the relationship between grit and well-being, with the indirect effect accounting for 26.32% of the total effect (indirect effect = 0.20, 95% CI [0.09-0.31]). In a parallel mediation model analyzing the subdimensions of physical literacy, the "interaction with the environment" emerged as the strongest mediator (indirect effect = 0.15, 95% CI [0.10-0.21]), accounting for 19.74% of the total effect. The indirect effects through "motivation" and "confidence and physical competence" were also significant but accounted for smaller proportions of the total effect (6.58% and 5.26%, respectively).

Conclusions: These findings serve as an initial step in understanding how physical literacy, particularly the ability to interact with the environment, partially mediates the relationship between grit and well-being among college students with obesity. Future interventional research aiming to enhance physical literacy-especially environmental engagement-is needed to confirm whether it can amplify the positive impact of grit on well-being. A multifaceted approach that fosters both psychological traits and physical competencies may prove beneficial in improving the psychological and physical health of this population.

Keywords: College students; Grit; Mediation analysis; Obesity; Physical literacy; Well-being.

Conflict of interest statement

The authors declare there are no competing interests.

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. 2025 May 5:11:20552076251334537.
doi: 10.1177/20552076251334537. eCollection 2025 Jan-Dec.

Concept of digital health literacy revisited: Using text network and topic model analysis

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Concept of digital health literacy revisited: Using text network and topic model analysis

Jiyoung Park et al. Digit Health. .

Abstract

Background: The rapid integration of ICT into healthcare has elevated the critical role of digital health literacy (DHL). However, the conceptual relationship between DHL and electronic health (eHealth), along with the impact of transformative events such as the Fourth Industrial Revolution and the COVID-19 pandemic, remains inadequately investigated.

Objective: This study seeks to analyze research trends in DHL across four distinct historical periods to uncover key themes and their temporal evolution.

Methods: A comparative analysis of 2645 abstracts from Scopus publications (1977-2022) was conducted, segmented into four periods: (I) emerging era (1977-2006), (II) establishment era (2007-2016), (III) diffusion era (2017-2020), and (IV) post-pandemic era (2021-present). Text network analysis identified core keywords, and Latent Dirichlet Allocation (LDA) extracted dominant topics and their temporal evolution.

Results: Since 2006, DHL research has exhibited consistent growth, underpinned by transformative advancements during the Fourth Industrial Revolution and further amplified by a significant surge in scholarly engagement in the post-pandemic era. Importantly, during the diffusion era (Period III), a divergence in the trajectories of "digital health literacy" and "electronic health literacy" emerged.Text network analysis revealed a progression toward greater uniformity in node sizes over time, coupled with an increase in the complexity and intricacy of connections between nodes. These findings indicate a growing diversity and nuanced understanding of concepts associated with DHL. Moreover, research in the post-pandemic era (Period IV) emphasized the critical role of DHL in addressing health disparities and advancing equitable access to healthcare.

Conclusion: The study reveals the dynamic progression of DHL research, catalyzed by technological advancements and global health crises. Strengthening DHL, particularly among vulnerable populations, is crucial for mitigating health disparities in a rapidly digitalizing world. Future research should prioritize the development of targeted interventions and examine DHL's impact across diverse sociocultural contexts.

Keywords: COVID-19; digital health literacy; electronic health literacy; fourth industrial revolution; text network analysis.

Conflict of interest statement

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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Review
. 2025 May 8.
doi: 10.1111/phn.13567. Online ahead of print.

Effect of Health Literacy on Attitudes Toward Cancer Screening Among Individuals Aged 30-70

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Review

Effect of Health Literacy on Attitudes Toward Cancer Screening Among Individuals Aged 30-70

Merve Tozlu et al. Public Health Nurs. .

Abstract

Objective: This study aimed to examine the variables affecting the health literacy level and attitude towards cancer screening in individuals between the ages of 30 and 70 and to determine the effect of health literacy level on the attitude towards cancer screening.

Methods: A cross-sectional study was conducted with a sample of 800 participants. Data were collected through self-reporting using the Personal Characteristics Information Form, the Turkish Health Literacy Scale, and the Attitude Scale for Cancer Screening.

Results: The study revealed that scores on the Attitude Scale for Cancer Screening varied significantly based on age, educational level, income status, presence of health insurance, history of cancer screening (p < 0.001), confirmed cancer diagnosis, gender (p = 0.001), and presence of chronic illness (p = 0.005). Similarly, Turkish Health Literacy Scale scores differed significantly according to age, marital status, place of residence, educational level, income, chronic illness status (p < 0.001), and gender (p = 0.002). Furthermore, the Turkish Health Literacy Scale score was identified as a significant predictor of the Attitude Scale for Cancer Screening score. (β = 0.423, p < 0.05).

Conclusion: Higher health literacy was associated with a positive attitude towards cancer screening. Nurses can contribute to the development of a positive attitude towards cancer screening in society through counseling and training initiatives to increase health literacy.

Keywords: attitude scale for cancer screening; cancer; health literacy; nursing.

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. 2025 May 8:fdaf050.
doi: 10.1093/pubmed/fdaf050. Online ahead of print.

Communication about COVID-19 with urban American Indian and Alaska Native peoples: the role of health literacy, trust, and information source

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Communication about COVID-19 with urban American Indian and Alaska Native peoples: the role of health literacy, trust, and information source

Amanda D Boyd et al. J Public Health (Oxf). .

Abstract

Background: Developing optimal health communication strategies about COVID-19 and vaccines requires an understanding of the health literacy level of populations, trusted sources of information, and perceptions of COVID-19 messaging. We examined how health literacy is related to knowledge about COVID-19 among American Indian and Alaska Native (AI/AN) peoples.

Methods: We surveyed 788 AI/AN peoples at five Tribal health organizations between January and May 2021. We assessed health literacy using a 4-item health literacy index, and knowledge of COVID-19 in three domains: protection against contracting COVID-19; contracting COVID-19, and clinical manifestations of contraction. Questions also included rating trust of COVID-19 information sources and perceptions of messaging.

Results: Participants had a high level of knowledge about COVID-19; however, health literacy was not significantly associated with any domain of COVID-19 knowledge. Participants perceived the most trusted source of COVID-19-related health information to be health professionals, followed by health clinics. Social media was the least trusted source of information. Tribal sources of information were rated on average higher quality than non-tribal sources.

Conclusions: AI/AN peoples had high levels of accurate knowledge about COVID-19 regardless of assessed health literacy. Information sources should include Tribal-led organizations and health professionals to increase uptake of COVID-19 messaging.

Keywords: Indigenous; communication; education; risk perception; vaccine.

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. 2025 May 8.
doi: 10.1002/jpn3.70069. Online ahead of print.

Parental education in pediatric dysphagia: A comparative analysis of three large language models

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Parental education in pediatric dysphagia: A comparative analysis of three large language models

Bülent Alyanak et al. J Pediatr Gastroenterol Nutr. .

Abstract

Objectives: This study evaluates the effectiveness of three widely used large language models (LLMs)-ChatGPT-4, Copilot, and Gemini-in providing accurate, reliable, and understandable answers to frequently asked questions about pediatric dysphagia.

Methods: Twenty-five questions, selected based on Google Trends data, were presented to ChatGPT-4, Copilot, and Gemini, and the responses were evaluated using a 5-point Likert scale for accuracy, the Ensuring Quality Information for Patients (EQIP) and DISCERN scales for information quality and reliability, and the Flesch-Kincaid Grade Level (FKGL) and Flesch Reading Ease (FRE) scores for readability. The performance of ChatGPT-4, Copilot, and Gemini was assessed by presenting the same set of questions at three different time points: August, September, and October 2024. Statistical analyses included analysis of variance, Kruskal-Wallis tests, and post hoc comparisons, with p values below 0.05 considered significant.

Results: ChatGPT-4 achieved the highest mean accuracy score (4.1 ± 0.7) compared to Copilot (3.1 ± 0.7) and Gemini (3.8 ± 0.8), with significant differences observed in quality ratings (p < 0.001 and p < 0.05, respectively). EQIP and DISCERN scores further confirmed the superior performance of ChatGPT-4. In terms of readability, Gemini achieved the highest scores (FRE = 48.7 ± 9.9 and FKGL = 10.1 ± 1.6).

Conclusions: While ChatGPT-4 generally provided more accurate and reliable information, Gemini produced more readable content. However, variability in overall information quality indicates that, although LLMs hold potential as tools for pediatric dysphagia education, further improvements are necessary to ensure consistent delivery of reliable and accessible information.

Keywords: ChatGPT; Copilot; Gemini; artificial intelligence; dysphagia.

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. 2025 May 8;15(1):16101.
doi: 10.1038/s41598-025-00936-0.

The chain mediating effect of self-efficacy and health literacy between proactive personality and health-promoting behaviors among Chinese college students

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The chain mediating effect of self-efficacy and health literacy between proactive personality and health-promoting behaviors among Chinese college students

Shouying Wang et al. Sci Rep. .

Abstract

Health-promoting behaviors are essential for college students as they develop lifelong health habits. To investigate how to cultivate health-promoting behaviors among college students, this study aimed to investigate the influence of proactive personality on health-promoting behaviors and to explore the mediating roles of self-efficacy and health literacy through a cross-sectional study. A total of 664 college students from six colleges in Xinxiang, China, were conveniently sampled to complete questionnaires, including the Proactive Personality Scale, General Self-Efficacy Scale, 12-item Short-Form Health Literacy Scale, and Short-Form Health Promotion Scale. Path analysis indicated that proactive personality was directly associated with health-promoting behaviors (effect value: 0.146). The mediating roles of self-efficacy (effect value: 0.165) and health literacy (effect value: 0.080) were significant. A chain mediating effect of self-efficacy and health literacy was also observed (effect value: 0.028). The positive effect of proactive personality (β = 0.146, P < 0.001), self-efficacy (β = 0.421, P < 0.001) and health literacy (β = 0.234, P < 0.001) on health-promoting behaviors was significant. These findings suggest that self-efficacy and health literacy play a chain mediating role between proactive personality and health-promoting behavior. Future interventions should target proactive personality, self-efficacy, and health literacy to enhance health-promoting behaviors in college students.

Keywords: College students; Health literacy; Health-promoting behavior; Proactive personality; Self-efficacy.

Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests. Ethics approval and consent to participate: This study was conducted in accordance with the principles of the Declaration of Helsinki. Informed consent was obtained from all subjects. Ethical approval was granted by the Ethics Committee of the Xinxiang Medical University [XYLL-20230335].

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Randomized Controlled Trial
. 2025 May 8;15(1):15982.
doi: 10.1038/s41598-025-01152-6.

Effects of health education based on self-determination theory on hemodialysis knowledge and self-management in maintenance hemodialysis patients

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Randomized Controlled Trial

Effects of health education based on self-determination theory on hemodialysis knowledge and self-management in maintenance hemodialysis patients

Jiquan Zhang et al. Sci Rep. .

Abstract

The purpose of this study was to examine the impact of health education based on self-determination theory on hemodialysis knowledge, self-management, interdialytic weight gain and anxiety and depression in maintenance hemodialysis patients. The study is a quasi-randomized control trial, a total of 86 maintenance hemodialysis patients who met the inclusion criteria were included equally in the intervention and control groups. The control group received routine care, and the intervention group received health education based on self-determination theory. Three months after the intervention, the intervention effects were evaluated using the Hemodialysis Related Knowledge Scale, Self-Management Behavior Scale, Interdialytic Weight Gain, and Hospital Anxiety and Depression Scale. Three months after the intervention, the hemodialysis knowledge scores of the intervention group was higher than that of the control group and baseline; the scores of the intervention group in problem solving, partnership, emotional processing, executive self-care dimensions and the total self-management scores were higher than that of the control group and baseline; the interdialytic weight gain of the intervention group was lower than that of the control group and baseline; the anxiety and depression scores of the intervention group were lower than that of the control group and baseline. All these differences were statistically significant (P < 0.05). Health education based on self-determination theory can improve the hemodialysis knowledge level and self-management ability of maintenance hemodialysis patients, and reduce the interdialytic weight gain and anxiety and depression level.

Keywords: Maintenance hemodialysis; Quasi-randomized control trial; Self-determination theory; Self-management.

Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests.

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Randomized Controlled Trial
. 2025 May 8:27:e58024.
doi: 10.2196/58024.

Efficacy of a Self-Guided Internet Intervention With Optional On-Demand Feedback Versus Digital Psychoeducation on Sleep Hygiene for University Students With Insomnia: Randomized Controlled Trial

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Free article
Randomized Controlled Trial

Efficacy of a Self-Guided Internet Intervention With Optional On-Demand Feedback Versus Digital Psychoeducation on Sleep Hygiene for University Students With Insomnia: Randomized Controlled Trial

Anna-Carlotta Zarski et al. J Med Internet Res. .
Free article

Abstract

Background: Internet-based cognitive behavioral therapy for insomnia (iCBT-I) provides flexibility but requires significant time and includes potentially challenging components such as sleep restriction therapy. This raises questions about its incremental effectiveness compared to less demanding minimal interventions such as sleep hygiene psychoeducation.

Objective: This study aimed to assess the incremental efficacy of self-guided iCBT-I with optional on-demand feedback for university students with insomnia compared to a single session of digital psychoeducation on sleep hygiene.

Methods: In a randomized controlled trial, 90 students with insomnia (Insomnia Severity Index ≥10) were randomly allocated to self-help-based iCBT-I (45/90, 50%) or one session of digital sleep hygiene psychoeducation with stimulus control instructions (active control group [aCG]: 45/90, 50%). The self-help-based iCBT-I consisted of 6 sessions on psychoeducation, sleep restriction, and stimulus control, including written feedback on demand from an eCoach. Assessments occurred at baseline (T1), 8 weeks after treatment (T2), and at a 6-month follow-up (T3) via web-based self-assessment and diagnostic telephone interviews. The primary outcome was insomnia severity at T2. Analyses of covariance were conducted in an intention-to-treat sample. Secondary outcomes included diagnoses of insomnia and major depression, sleep quality, sleep efficiency, worrying, recovery experiences, recovery activities, presenteeism, procrastination, cognitive irritation, and recuperation in sleep.

Results: There was no difference in insomnia severity at T2 between the iCBT-I group (mean 11.27, SD 5.21) and aCG group (mean 12.36, SD 4.16; F1,989.03=1.12; P=.29; d=-0.26; 95% CI 0.68 to 0.17). A significant difference emerged at T3 (iCBT-I: mean 9.43, SD 5.36; aCG: mean 12.44, SD 5.39; F1,426.15=4.72; P=.03), favoring iCBT-I with a medium effect (d=-0.57; 95% CI 1.07 to -0.06). Most secondary outcomes revealed no significant differences between the groups. In total, 51% (23/45) of participants in the iCBT-I group completed all 6 sessions, and 69% (31/45) completed the 4 core sessions.

Conclusions: In the short term, students might benefit from low-intensity, easily accessible digital sleep hygiene psychoeducation or iCBT-I. However, it appears that iCBT-I offers superiority over sleep hygiene psychoeducation in the long term.

Trial registration: German Clinical Trials Register DRKS00017737; https://drks.de/search/de/trial/DRKS00017737.

Keywords: CBT-I; active control group; cognitive behavioral therapy for insomnia; insomnia; internet intervention; randomized controlled trial; university students.

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. 2025 May 8;13(1):484.
doi: 10.1186/s40359-025-02769-y.

Social networking sites use and life satisfaction: a moderated mediation model of e-health literacy, fatigue, uncertainty, and stress

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Social networking sites use and life satisfaction: a moderated mediation model of e-health literacy, fatigue, uncertainty, and stress

Saeed Pahlevan Sharif et al. BMC Psychol. .

Abstract

Excessive social media use during health crises can lead to information overload and psychological distress, yet the mechanisms underlying this relationship remain unclear. This study investigated how social networking sites (SNS) affected life satisfaction during the COVID-19 pandemic in Iran and whether this relationship was explained by SNS fatigue, uncertainty about disease, and stress. The research also examined whether e-health literacy was a protective factor in this process. Results confirmed that SNS use negatively affected life satisfaction through a sequential pathway of increased fatigue, uncertainty, and stress. E-health literacy moderated the initial link between SNS use and fatigue, with higher literacy weakening this relationship. The results demonstrate the complex relationship between SNS use and wellbeing during health crises and highlight the potential protective role of e-health literacy.

Keywords: E-health literacy; Life satisfaction; SNS fatigue; Social networking sites; Stress.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: The present study was performed in accordance with the international ethical standards of the Declaration of Helsinki. This study was approved by the ethics committee of Mazandaran University of Medical Sciences (IR.MAZUMS.REC.1399.008). Participants were informed that their participation was voluntary and that their responses would be published anonymously as group data. They completed the online informed consent form. Consent for publication: Not Applicable. Competing interests: The authors declare no competing interests.

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Multicenter Study
. 2025 May 8;25(1):657.
doi: 10.1186/s12913-025-12695-9.

The relationship between diabetes distress and eHealth literacy among patients under 60 years of age with diabetes: a multicenter cross-sectional survey

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Multicenter Study

The relationship between diabetes distress and eHealth literacy among patients under 60 years of age with diabetes: a multicenter cross-sectional survey

Haoyang Chen et al. BMC Health Serv Res. .

Abstract

Background: Given the increasing prevalence of digital health management, eHealth literacy plays a crucial role in the self-management of diabetes. eHealth literacy refers to an individual's ability to use electronic devices and online resources to manage health issues. In diabetes self-care, the way patients effectively access and apply health information directly impacts disease management outcomes. However, limited research has examined eHealth literacy among diabetes patients, and there is insufficient evidence to show its specific impact on diabetes distress. Therefore, this study aims to assess the eHealth literacy of diabetes patients and explore its relationship with diabetes distress.

Methods: This cross-sectional study was conducted from November 2022 to July 2023 and involved 260 diabetes patients from three tertiary hospitals in Nantong, China. The participants were selected using convenience sampling, and all participants were adults aged 60 years or younger who were capable of communicating in Chinese. Individuals with severe mental illness, hearing or visual impairments, or physical conditions that hindered their participation were excluded. The eHealth Literacy Scale (eHEALS) was used to assess the participants' eHealth literacy. Additionally, data were collected on social support, anxiety, depression, and diabetes distress (DDS). Structural equation modeling (SEM) was used to analyze the data and explore the pathways through which eHealth literacy influences diabetes distress.

Results: eHealth literacy was significantly negatively correlated with anxiety, depression, and diabetes distress (r = - 0.408, p < 0.01; r = - 0.294, p < 0.01; and r = - 0.398, p < 0.01, respectively). Additionally, eHealth literacy was significantly positively correlated with social support (r = 0.346, p < 0.01). The results of the mediation analysis revealed that social support and psychological factors (anxiety and depression) played mediating roles in the relationship between eHealth literacy and diabetes distress.

Conclusions: This study shows that eHealth literacy significantly influences the perception of distress among patients with diabetes, with social support and psychological status playing important mediating roles. Enhancing eHealth literacy, especially patients' ability to access and apply health information, may help reduce diabetes distress. Future research should explore more representative samples and long-term study designs to validate these findings and evaluate the effectiveness of various interventions.

Keywords: Anxiety; Depression; Diabetes; Distress; Social support; eHealth.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: This study involved research on human participants and was conducted in accordance with the Declaration of Helsinki and with the approval of the Ethics Committee of the Nantong Second People’s Hospital (Ethics Approval Number: 2022-039). The authors confirm that all research methods were carried out in accordance with the relevant guidelines and regulations. Informed consent was obtained from all participants and/or their legal guardians. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

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. 2025 May 8:9:e69611.
doi: 10.2196/69611.

Boosting Digital Health Engagement Among Older Adults in Hong Kong: Pilot Pre-Post Study of the Generations Connect Project

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Boosting Digital Health Engagement Among Older Adults in Hong Kong: Pilot Pre-Post Study of the Generations Connect Project

Aaron Wan Jia He et al. JMIR Form Res. .

Abstract

Background: Older adults' utilization of digital health care remains low despite a high demand for regular health services. Easily accessible eHealth interventions designed for older adults are needed.

Objective: This study aimed to examine the feasibility and effectiveness of an intergenerational, home-based eHealth literacy intervention package on older adults in Hong Kong.

Methods: In this study, 101 older adults (n=64, 63.4% female) with a median age of 80 (IQR 77-85) years received an intergenerational, home-based eHealth literacy intervention package, delivered by trained university student interventionists. The intervention (median 60, IQR 40.8-70 minutes) included personalized guidance on using mobile health apps, QR code scanners and instant messaging, and access to online health information, along with recommendations for physical and mental well-being. Following the intervention, a daily health-coaching message was sent to older adults via WhatsApp for 14 days. eHealth literacy, health, and lifestyle were assessed at baseline and at a 2-week follow-up using paired t tests.

Results: Retention rate for the 2-week follow-up was 70.3% (71/101). Compared to baseline, eHealth literacy scores increased by 2.39 points (P=.11; Cohen d=0.20), and daily smartphone use rose by 0.45 hours (P=.07; Cohen d=0.05). Participants self-reported increased physical activity (50/71, 70%), more frequent viewing of health videos (43/70, 61%), and improved handwashing practices (39/71, 55%). The intervention achieved a high satisfaction rating of 4.32 out of 5.

Conclusions: The intergenerational, home-based eHealth literacy intervention package was feasible and acceptable, showing promise for increasing older adults' engagement with digital health care resources and promoting healthy behaviors. Future studies should explore longer-term effects and ways to further improve the intervention.

Keywords: eHealth literacy; health promotion; home-based intervention; intergenerational learning; older adults.

Conflict of interest statement

None declared.

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. 2025 May 8;22(5):e1004577.
doi: 10.1371/journal.pmed.1004577. eCollection 2025 May.

Change in willingness for surgery and risk of joint replacement after an education and exercise program for hip/knee osteoarthritis: A longitudinal cohort study of 55,059 people

Affiliations

Change in willingness for surgery and risk of joint replacement after an education and exercise program for hip/knee osteoarthritis: A longitudinal cohort study of 55,059 people

Belinda J Lawford et al. PLoS Med. .

Abstract

Background: Numerous studies report that education and exercise interventions can shift people's willingness to undergo joint replacement surgery for osteoarthritis. We aimed to investigate whether becoming unwilling to undergo surgery following an education and exercise intervention for hip and knee osteoarthritis is associated with lower probability of receiving actual surgery.

Methods and findings: This was a register-based cohort study including people from the Swedish Osteoarthritis Register who underwent a 3-month education and exercise intervention for knee or hip osteoarthritis. Participants self-reported their willingness to have joint replacement surgery ('yes' or 'no') and were grouped based on their response pre- and post-intervention (always willing for surgery; became unwilling for surgery; never willing for surgery; became willing for surgery). Data on joint replacement surgery was obtained through the Swedish Arthroplasty Register. The probability and hazard of surgery occurring, as well as the mean time without surgery was calculated up to 5-years (primary outcome) and 9-years (secondary outcome) post-intervention. We adjusted for age, sex, body mass index (BMI), education, joint pain, quality of life, walking difficulties, number of prior visits with an orthopedic surgeon, prior joint surgeries in the knee or hip (other than joint replacement), and comorbidities. 55,059 people were included, 69% were female (N = 37,739), with a mean age 66years (standard deviation [SD] = 9.3), and a BMI of 27.5 (SD = 4.9). In total, 70% (N = 38,386) were never willing for surgery, 14% (N = 7,736) were always willing for surgery, 10% (N = 5,649) became unwilling for surgery, and 6% (N = 3,288) became willing for surgery. Compared to those who were always willing for surgery, participants who became unwilling had a 20% (95% confidence interval [CI]: 18, 22%) lower probability of having surgery by 5-years post-intervention. This corresponded to delaying surgery by 1.1 (95% CI: 1.0, 1.1) years. Compared to those who were always willing for surgery, the hazard of surgery occurring at 1-year post-intervention was lower in those who became unwilling (hazard ratio (HR) 0.5 [95% CI: 0.4, 0.5]), though was then higher at 5-years (HR 1.4 [95% CI: 1.2, 1.7]). Estimates remained stable from 5 to 9 years. Limitations of our study include the inability to account for all potential confounders, and to infer the contribution of the intervention to change in willingness for surgery due to the absence of a control group. Data were collected in Sweden, generalisability to other countries may be limited.

Conclusions: Becoming unwilling for joint replacement surgery following an education and exercise program for hip and knee osteoarthritis could reduce the number of joint replacement surgeries by 20% at 5 years post-intervention, with the possibility of maintaining most of this reduction up to 9 years post-intervention. Interventions that can shift willingness to undergo surgery may thus result in relevant delays and reductions in future joint replacements.

Conflict of interest statement

I have read the journal's policy and the authors of this manuscript have the following competing interests: ME is a consultant for Grunenthal Sweden AB and Key2Compliance.

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Randomized Controlled Trial
. 2025 May-Jun;39(3):335-345.
doi: 10.1016/j.pedhc.2024.10.013. Epub 2025 May 8.

Evaluation of an Interactive, Educational Website Developed for Adolescents to Learn About Pediatric Clinical Trials: DigiKnowIt News

Randomized Controlled Trial

Evaluation of an Interactive, Educational Website Developed for Adolescents to Learn About Pediatric Clinical Trials: DigiKnowIt News

Alison E Parker et al. J Pediatr Health Care. 2025 May-Jun.

Abstract

Introduction: Pediatric clinical trials are important for advancing treatments for youth; however, recruitment remains a challenge. This study examines the effectiveness of DigiKnowIt News, a website designed to educate adolescents about clinical trials.

Method: Parent-adolescent pairs were randomly assigned to intervention (N = 83) or wait-list control (N = 96) groups. Pairs completed online pretest and posttest questionnaires related to knowledge and attitudes about research.

Results: Adolescents and parents in the intervention group, compared to the wait-list control, significantly increased in their familiarity with and positive attitudes toward clinical trials. Adolescents improved in their confidence for participating in clinical trials. Promising findings emerged with marginal increases in positive beliefs about clinical trials and likelihood of allowing an adolescent to participate. Participants reported high levels of satisfaction with DigiKnowIt News.

Discussion: Providing adolescents and parents with information in fun, interactive, and engaging ways can inform their decision-making about clinical trials.

Keywords: Clinical trials; adolescent; decision-making; education.

Conflict of interest statement

Conflicts of Interest Alison Parker, Tracy Scull, Jada Green, and Kathryn Stump are all employees at a small business that has a financial interest in the sale of DigiKnowIt News. The conflict of interest is minimal and is further minimized through careful supervision of the online data collection procedures. The data collected in the proposed study was entered into the computer by participants using an online data collection system.

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Effects of Application-Based Information Provision on Parents' Health Literacy: An Open-Label, Nonrandomized, Parallel-Controlled Trial

Masahiko Sakamoto et al. Health Lit Res Pract. 2025 Apr.

Abstract

Background: In recent years, parents have had more opportunities to use applications (apps) to access health care information.

Objective: In this study, we aimed to evaluate whether the use of an app that provides health care information on children improves parents' health literacy.

Methods: This open-label, nonrandomized, parallel-controlled trial was conducted at two health centers in Japan. We recruited parents of 1.5-year-old children and introduced the Oshiete! Doctor app to the intervention group. The primary outcome was a change in the parents' health literacy scores (HLSs).

Key results: A total of 200 parents were included in this study. The mean HLSs slightly improved in both groups, with greater improvement observed in the intervention group than in the control group. However, the difference was not statistically significant. In the intervention group, participants with higher app ratings showed greater improvement in their HLSs after the intervention.

Conclusions: The introduction of an app that provides health care information on children did not show a statistically significant improvement in parents' health literacy. In the intervention group, participants with higher app ratings showed greater improvement in their HLSs after the intervention. Future research on apps and parental health literacy should also consider the frequency of app use. Larger, longer-term studies are needed. [HLRP: Health Literacy Research and Practice. 2025;9(2):e64-e71.].

Plain language summary

Plain Language Summary This study assessed whether using a child health information app could improve parents' health literacy. Parents of 1.5-year-olds were assigned to either an intervention or control group. Although health literacy improved more in the intervention group, the difference was not statistically significant. Higher app ratings were linked to greater literacy gains.

Conflict of interest statement

Disclosure: The authors have disclosed no potential conflicts of interest, financial or otherwise.

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. 2025 May 8;56(1):111.
doi: 10.1007/s12029-025-01241-9.

The Association Between Health Literacy and Colorectal Cancer Screening: Findings Using a Three-Question Health Literacy Measure

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The Association Between Health Literacy and Colorectal Cancer Screening: Findings Using a Three-Question Health Literacy Measure

Alfonsus Adrian H Harsono et al. J Gastrointest Cancer. .

Abstract

Purpose: Health literacy (HL) can impact health behaviors including colorectal cancer (CRC) screening. Prior findings using extensive measures of HL suggested that low HL is associated with lower CRC screening rates. We hypothesized that low HL, when measured using a clinically applicable three-question measure, would also be associated with low CRC screening rates.

Methods: Data collected from the 2016 Behavioral Risk Factor Surveillance System (BRFSS) was utilized from 17 states that included a three-question HL measure. Participants ages 50-75 were included. The HL scores were categorized as adequate, marginal, or limited HL. The primary outcome was United States Preventative Services Task Force (USPSTF) recommendation-concordant CRC screening. The relationship between HL and CRC screening was examined using multivariable logistic regression.

Results: Among 38,044 participants who met inclusion criteria, 47.2% (n = 17,950), 49.9% (n = 18,989), and 2.9% (n = 1105) had adequate, marginal, and limited HL, respectively. Lower HL levels were associated with lower adherence to USPSTF CRC screening recommendations: 73.3% for adequate, 68.0% for marginal, and 48.9% for limited HL (p < 0.01). Respondents with limited HL were 45% less likely to undergo CRC screening (OR = 0.55; 95%CI: 0.48-0.63). A significant interaction (p < 0.01) between health literacy and sex was identified. CRC screening difference among HL levels was more pronounced for male (OR = 0.48; 95% CI: 0.40-0.79) than female respondents (OR = 0.63; 95% CI: 0.52-0.76).

Conclusion: Limited health literacy is associated with significantly lower rates of appropriate CRC screening, particularly for males. This three-question HL measure provides a clinically applicable tool to identify people at risk for lack of CRC screening.

Keywords: Colorectal cancer screening; Health disparities; Health literacy; Social determinants of health.

Conflict of interest statement

Declarations. Ethics Approval: This is an observational study using publicly available database. The University of Alabama at Birmingham (UAB) institutional review board (IRB) has exempted requirements for any ethical approval. Conflict of Interest: The authors declare no competing interests.

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. 2025 Jun;23(2):e70105.
doi: 10.1002/msc.70105.

An Integrated Education and Exercise Programme for Tamil People With Osteoarthritis Knee

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An Integrated Education and Exercise Programme for Tamil People With Osteoarthritis Knee

Malarvizhi Devadhason et al. Musculoskeletal Care. 2025 Jun.

Abstract

Background: Osteoarthritis knee (OA knee) is a chronic joint condition associated with pain, disability and reduced quality of life. Guidelines recommend self-management, patient education, behavioural support and tailored exercise as core components of non-surgical treatment.

Purpose: To develop and evaluate an OA knee patient education booklet and a physiotherapist-led integrated programme involving the core components of non-surgical care to improve clinical outcomes in Tamil-speaking people with OA knee of Tamil Nadu state (Population 72.1 million, 2011 census), India.

Methods: A patient education booklet was developed through an iterative process and evaluated in 50 patients, carers, and physiotherapists. The impact of the integrated programme on knee pain, function, physical performance, and adherence was assessed at six weeks and during a follow-up at six months.

Results: The Tamil booklet was easy to read, useful and relevant. 31 patients (26 women; 5 men, average age 60.4 years) took part in the integrated programme. Improvements in pain, function and performance measures were statistically significant and clinically meaningful. The majority of them found the programme useful and satisfactory and reported that their condition improved. There were no adverse events.

Conclusions: Our Tamil OA knee education booklet was deemed relevant and useful. The integrated education and exercise programme was feasible and acceptable and our findings provided preliminary evidence on its clinical benefits in people with OA knee.

Keywords: India; Tamil; education; exercise; function; knee; osteoarthritis.

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. 2025 Feb 28;38(3):221-226.
doi: 10.1080/08998280.2025.2470033. eCollection 2025.

Evolution of patient education materials from large-language artificial intelligence models on complex regional pain syndrome: are patients learning?

Affiliations

Evolution of patient education materials from large-language artificial intelligence models on complex regional pain syndrome: are patients learning?

Anuj Gupta et al. Proc (Bayl Univ Med Cent). .

Abstract

Objectives: This study assessed the comprehensiveness and readability of medical information about complex regional pain syndrome provided by ChatGPT, an artificial intelligence (AI) chatbot, and Google using standardized scoring systems.

Design: A Google search was conducted using the term "complex regional pain syndrome," and the first 10 frequently asked questions (FAQs) and answers generated were recorded. ChatGPT was presented these FAQs generated by Google, and its responses were evaluated alongside Google's answers using multiple metrics. ChatGPT was then asked to generate its own set of 10 FAQs and answers.

Results: ChatGPT's answers were significantly longer than Google's in response to both independently generated questions (330.0 ± 51.3 words, P < 0.0001) and Google-generated questions (289.7 ± 40.6 words, P < 0.0001). ChatGPT's answers to Google-generated questions were more difficult to read based on the Flesch-Kincaid Reading Ease Score (13.6 ± 10.8, P = 0.017).

Conclusions: Our findings suggest that ChatGPT is a promising tool for patient education regarding complex regional pain syndrome based on its ability to generate a variety of question topics with responses from credible sources. That said, challenges such as readability and ethical considerations must be addressed prior to its widespread use for health information.

Keywords: Artificial intelligence; complex regional pain syndrome; education; pain; rehabilitation.

Conflict of interest statement

The authors report no funding or conflict of interest.

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Randomized Controlled Trial
. 2025 May 7;25(1):689.
doi: 10.1186/s12903-025-06069-0.

Evaluating the impact of AI-generated educational content on patient understanding and anxiety in endodontics and restorative dentistry: a comparative study

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Randomized Controlled Trial

Evaluating the impact of AI-generated educational content on patient understanding and anxiety in endodontics and restorative dentistry: a comparative study

Shahid Islam. BMC Oral Health. .

Abstract

Background: Effective patient education is critical in enhancing treatment outcomes and reducing anxiety in dental procedures. This study compares the effectiveness of AI-generated educational materials with traditional methods in improving patient comprehension and reducing anxiety during endodontic and restorative dental treatments.

Methods: A cross-sectional, comparative study was conducted with 100 participants undergoing restorative or endodontic procedures. Patients were randomized into two groups: those receiving AI-generated instructional materials (via ChatGPT) and those receiving traditional education (verbal explanations and pamphlets). Baseline knowledge and post-intervention knowledge retention were assessed using structured tests. Patient perceptions of clarity, usefulness, comprehensiveness, trust, and anxiety were measured using Likert-scale surveys. Three dental experts evaluated the educational content for accuracy and suitability. Statistical analysis included t-tests and Cohen's kappa to measure inter-rater reliability.

Results: AI-generated materials significantly outperformed traditional methods in all measured dimensions, including clarity (4.42 vs. 3.25), usefulness (4.63 vs. 3.50), comprehensiveness (4.50 vs. 3.29), trust (4.00 vs. 2.96), and anxiety reduction (mean anxiety score: 2.63 vs. 3.38, p < 0.001). Pre- and post-intervention knowledge assessments revealed substantial knowledge improvement in the AI group. Expert evaluations confirmed the accuracy and suitability of AI-generated materials, with high inter-rater reliability (κ = 0.75, p < 0.001).

Conclusions: AI-generated educational materials demonstrate superior effectiveness in improving patient comprehension and reducing anxiety compared to traditional methods. Their integration into dental practice could enhance patient satisfaction and streamline the educational process, particularly for complex or anxiety-inducing procedures. Future research should explore their application in diverse dental specialties and assess long-term impacts on patient behavior and clinical outcomes.

Keywords: AI in healthcare; Artificial intelligence; ChatGPT; Comprehensiveness; Dental anxiety; Endodontics; Patient education; Restorative dentistry; Trustworthiness.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: This study was approved by the Institutional Review Board (IRB) of Fatima Jinnah Dental College, Karachi, Pakistan via certificate number AUG-2024-OPR03. Written informed consent was obtained from all participants before data collection. All procedures performed in this study involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Consent for publication: Not applicable. Clinical trial number: Not applicable. Competing interests: The authors declare no competing interests.

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. 2025 May 5:S0099-2399(25)00212-2.
doi: 10.1016/j.joen.2025.04.015. Online ahead of print.

Evaluating Large Language Models in Addressing Patient Questions on Endodontic Pain: A Comparative Analysis of accessible chatbots

Affiliations

Evaluating Large Language Models in Addressing Patient Questions on Endodontic Pain: A Comparative Analysis of accessible chatbots

Sanaa Aljamani et al. J Endod. .

Abstract

Background: Patients increasingly use large language models (LLMs) for health-related information, but their reliability and usefulness remain controversial. Continuous assessment is essential to evaluate their role in patient education.

Aims: This study evaluates the performance of ChatGPT 3.5 and Gemini in answering patient inquiries about endodontic pain.

Methods: A total of 62 frequently asked questions on endodontic pain were categorized into etiology, symptoms, management, and incidence. Responses from ChatGPT 3.5 and Gemini were assessed using standardized tools, including the Global Quality Scale (GQS), CLEAR reliability tool, and readability indices (Flesch-Kincaid and SMOG).

Results: Compared to Gemini, ChatGPT 3.5 responses scored significantly higher in terms of overall quality (GQS: 4.67-4.9 vs. 2.5-4, p < 0.001) and reliability (CLEAR: 23.5-23.6 vs. 19.35-22.7, p < 0.05). However, it required a higher reading level (SMOG: 14-17.6) compared to Gemini (8.7-11.3, p < 0.001). Gemini's responses were more readable (6th-7th grade level) but lacked depth and completeness.

Conclusion: While ChatGPT 3.5 outperformed Gemini in quality and reliability, its complex language reduced accessibility. In contrast, Gemini's simpler language enhanced readability but sacrificed comprehensiveness. These findings highlight the need for professional oversight in integrating AI-driven tools into healthcare communication to ensure accurate, accessible, and empathetic patient education.

Keywords: ChatGPT 3.5; Endodontic pain; Gemini; Large Language Models (LLMs); Patient Education.

Conflict of interest statement

CONFLICT OF INTEREST STATEMENT All authors declare that they have no conflict of interest.

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. 2025 May 5:206:112776.
doi: 10.1016/j.exger.2025.112776. Online ahead of print.

Influence of health literacy and self-management on quality of life among older adults with hypertension and diabetes in Northwest China

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Free article

Influence of health literacy and self-management on quality of life among older adults with hypertension and diabetes in Northwest China

Yiliyaer Aihemaiti et al. Exp Gerontol. .
Free article

Abstract

Objective: This study investigated the relationship between health literacy, self-management, and quality of life among older adults diagnosed with hypertension and diabetes. Additionally, the influence of these factors on quality of life was assessed to provide a theoretical basis for enhancing the well-being of individuals with chronic conditions.

Methods: A cohort of 600 older adults diagnosed with hypertension and diabetes were recruited in Xinjiang, China. Data were collected through a questionnaire survey, and the relationship between health literacy, self-management levels, and quality of life were analysed using a structural equation model (SEM).

Results: Of the 600 distributed questionnaires, 556 were completed. Among the older adults with hypertension and diabetes, 17 (3.0 %) demonstrated very adequate health literacy, 188 (33.8 %) had adequate health literacy, 67 (12.1 %) exhibited possible insufficient health literacy, and 284 (51.1 %) were categorized as having insufficient health literacy. The mean self-efficacy score was 6.97 ± 1.03, reflecting low levels of self-management. The average Physical Component Summary score for quality of life was 51.10 ± 12.80, while the average Mental Component Summary score was 70.89 ± 9.43. SEM analysis indicated that quality of life exerted a significant positive effect on health literacy (β = 0.369, P < 0.001) and self-management (β = 0.133, P < 0.01). Furthermore, health literacy was found to significantly positively influence self-management (β = 0.210, P < 0.01).

Conclusion: Quality of life in older adults with chronic conditions is significantly influenced by their health literacy and self-management levels. Higher health literacy and improved self-management are associated with enhanced overall quality of life.

Keywords: Chronic disease; Health literacy; Quality of life; Self-management; Structural equation modeling.

Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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. 2025 Apr 28;46(5):104653.
doi: 10.1016/j.amjoto.2025.104653. Online ahead of print.

Effectiveness of 3D animation tools in patient education on cochlear implantation

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Free article

Effectiveness of 3D animation tools in patient education on cochlear implantation

Nienke C Homans et al. Am J Otolaryngol. .
Free article

Abstract

Purpose: Video animations have emerged as effective tools for patient education across various medical fields. Although evidence is mixed, animations show promise in enhancing comprehension, especially in fields like audiology, where verbal communication can be challenging, and the benefits may be even higher. This study explores whether 3D video animations improve patient education during the cochlear implantation (CI) selection process.

Materials and methods: A prospective cohort study was conducted at the Cochlear Implant Center, Erasmus University Medical Center, Rotterdam. Forty-six adult patients were included in the study and divided into two groups: one receiving the standard CI selection process and the other receiving the same process with additional 3D video animations. Participants completed a questionnaire assessing their knowledge, self-assessment of their knowledge, and satisfaction. The group with animations also answered additional questions about their experience with the animations.

Results: The group receiving the videos reported significantly higher self-assessment knowledge scores, particularly regarding rehabilitation. However, there were no significant differences in objective knowledge scores between the two groups. Satisfaction with the videos was high, with most participants sharing them with family and friends.

Conclusion: 3D video animations enhanced patients' self-perceived knowledge, particularly regarding rehabilitation, but did not significantly improve actual knowledge scores. The findings suggest that video animations are a promising tool for patient education in the CI selection process and warrant further investigation with larger sample sizes.

Keywords: 3D animation; Cochlear implant selection; Digital health; Health communication; Self-perceived knowledge.

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. 2025 May 5:201:105961.
doi: 10.1016/j.ijmedinf.2025.105961. Online ahead of print.

The actual performance of large language models in providing liver cirrhosis-related information: A comparative study

Affiliations

The actual performance of large language models in providing liver cirrhosis-related information: A comparative study

Yanqiu Li et al. Int J Med Inform. .

Abstract

Objective: With the increasing prevalence of large language models (LLMs) in the medical field, patients are increasingly turning to advanced online resources for information related to liver cirrhosis due to its long-term management processes. Therefore, a comprehensive evaluation of real-world performance of LLMs in these specialized medical areas is necessary.

Methods: This study evaluates the performance of four mainstream LLMs (ChatGPT-4o, Claude-3.5 Sonnet, Gemini-1.5 Pro, and Llama-3.1) in answering 39 questions related to liver cirrhosis. The information quality, readability and accuracy were assessed using Ensuring Quality Information for Patients tool, Flesch-Kincaid metrics and consensus scoring. The simplification and their self-correction ability of LLMs were also assessed.

Results: Significant performance differences were observed among the models. Gemini scored highest in providing high-quality information. While the readability of all four LLMs was generally low, requiring a college-level reading comprehension ability, they exhibited strong capabilities in simplifying complex information. ChatGPT performed best in terms of accuracy, with a "Good" rating of 80%, higher than Claude (72%), Gemini (49%), and Llama (64%). All models received high scores for comprehensiveness. Each of the four LLMs demonstrated some degree of self-correction ability, improving the accuracy of initial answers with simple prompts. ChatGPT's and Llama's accuracy improved by 100%, Claude's by 50% and Gemini's by 67%.

Conclusion: LLMs demonstrate excellent performance in generating health information related to liver cirrhosis, yet they exhibit differences in answer quality, readability and accuracy. Future research should enhance their value in healthcare, ultimately achieving reliable, accessible and patient-centered medical information dissemination.

Keywords: Accuracy Assessment; Large Language Model; Liver Cirrhosis; Quality Assessment; Readability Assessment.

Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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. 2025 May 3:123:110489.
doi: 10.1016/j.clinimag.2025.110489. Online ahead of print.

The utility of ChatGPT in musculoskeletal imaging-related patient education

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The utility of ChatGPT in musculoskeletal imaging-related patient education

Aayush Sharma et al. Clin Imaging. .
No abstract available

Keywords: Arthritis; ChatGPT; Large language model; Musculoskeletal radiology; Patient education; Trauma.

Conflict of interest statement

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Avneesh Chhabra reports a relationship with ICON Medical WLL that includes: consulting or advisory. Avneesh Chhabra reports a relationship with Treace Medical Concepts Inc that includes: consulting or advisory. Avneesh Chhabra reports a relationship with Image biopsy lab that includes: consulting or advisory and travel reimbursement. Avneesh Chhabra reports a relationship with Telemedicine clinics that includes: speaking and lecture fees. Royalties- jaypee and wolters All unrelated to this work. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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. 2025 May 6:63:567-573.
doi: 10.1016/j.gerinurse.2025.04.004. Online ahead of print.

Relationship between stigma and negative emotions among patients with Parkinson's disease: The mediating role of health literacy and family function

Affiliations

Relationship between stigma and negative emotions among patients with Parkinson's disease: The mediating role of health literacy and family function

Aoxue Zhu et al. Geriatr Nurs. .

Abstract

Background: Parkinson's disease is a neurodegenerative disorder causing physical and psychological challenges. Stigma exacerbates negative emotions, resulting in anxiety and depression, as well as undermining self-perception and social participation. Health literacy aids in disease management, and family function plays a crucial supportive role. However, the interplay between these variables remains underexplored.

Objective: To examine the chain mediating effects of health literacy and family function between stigma and negative emotions in patients with Parkinson's disease.

Methods: This study adopted a cross-sectional design, recruiting eligible patients from a tertiary hospital in Guangzhou, China. A total of 245 participants completed questionnaires on stigma, health literacy, family function and negative emotions. Statistical analyses were performed using Spearman's correlation and mediation effect analysis.

Results: Negative emotions were positively correlated with stigma (β = 0.584) and inversely associated with health literacy (β = -0.258) and family function (β = -0.144). Mediation effect analysis showed that the mediating effects of health literacy, family function, and their combined effects on the relationship between stigma and negative emotions were 0.033, 0.020, and 0.008, respectively, accounting for 8.89%, 5.39%, and 2.16% of the total effect.

Conclusions: Stigma in patients with Parkinson's disease not only directly affects negative emotions but also indirectly influences them through health literacy and family function.

Keywords: Family function; Health literacy; Mediation analysis; Negative emotions; Parkinson’s disease; Stigma.

Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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. 2025 May 6:kqaf014.
doi: 10.1093/occmed/kqaf014. Online ahead of print.

Occupational health literacy and affecting factors on healthcare workers

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Occupational health literacy and affecting factors on healthcare workers

E Karasu et al. Occup Med (Lond). .

Abstract

Background: In the realm of occupational accidents, the healthcare sector holds a significant position as it is classified as a highly hazardous workplace, thus bearing a heightened probability of accidents. Consequently, it becomes imperative to assess the occupational Health Literacy (OHL) of healthcare workers and identify the influencing factors.

Aims: The aim is to determine the OHL levels of healthcare workers and examine their relationship with demographic, socio-cultural characteristics, and variables related to the work environment.

Methods: This cross-sectional survey was conducted among 200 healthcare workers employed in healthcare services, administrative services, and support services at an education and research hospital in Niğde, Turkey, from November-December 2023. Data collection involved the utilization of a personal information form encompassing participants' socio-demographic characteristics and occupational health practices, along with the OHL Scale. Descriptive statistics, intergroup difference analyses, and multiple regression analysis were employed for data analysis.

Results: The participants demonstrated an average OHL score of 94.07 ± 11.33. They scored highest in Understanding occupational health and safety (OHS) Information (40.93) and lowest in Evaluating OHS Information (9.57). OHL among healthcare workers varied based on demographics, socio-cultural factors, and work-related variables. Age, education, tenure, vaccination, regular health screenings, workplace accidents and personal protective equipment (PPE) usage positively impacted OHL.

Conclusions: Findings revealed participants possess a certain level of OHL. Age, education, tenure, vaccination, regular health screenings, workplace accidents and PPE usage accounted for 53% of OHL variance. Enhancing workplace safety measures and improving healthcare workers' OHL are recommended.

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. 2025 May 7;20(5):e0321780.
doi: 10.1371/journal.pone.0321780. eCollection 2025.

Predictive factors for limited health literacy among persons with cirrhosis: A Swedish explorative cross-sectional study

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Predictive factors for limited health literacy among persons with cirrhosis: A Swedish explorative cross-sectional study

Maria Hjorth et al. PLoS One. .

Abstract

Introduction: Fatigue and altered cognitive capacity are common symptoms following cirrhosis. Patients consider information about cirrhosis difficult to understand. Health literacy levels vary among persons with chronic illnesses, which can hamper participation in and adaptation to treatment, potential restrictions and recommendations. Limited health literacy might also lead to decreased autonomy.

Purpose: The aim was to explore predictors of limited health literacy among adults with cirrhosis.

Materials and methods: This cross-sectional study explored health literacy among 167 Swedish adults with cirrhosis, 94 men and 73 women with a median age of 65 years using the 'Newest Vital Sign' instrument. Predictors of limited health literacy were examined in relation to patient characteristics and cirrhosis disease events. The study is reported following the STROBE guidelines.

Results: The prevalence of limited health literacy was 58%. Low education and covert hepatic encephalopathy were associated with limited health literacy (p < 0.05).

Conclusion: Limited health literacy is common among Swedish adults with cirrhosis. Both covert hepatic encephalopathy and low education might be predictors of limited health literacy. Healthcare providers should tailor their patient education based on the patient's literacy level to facilitate understanding, learning and self-management.

Conflict of interest statement

The authors have declared that no competing interests exist.

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. 2025 Apr 17;15(4):135.
doi: 10.3390/nursrep15040135.

Nursing Complexity and Health Literacy as Determinants of Patient Outcomes: A Prospective One-Year Multicenter Cohort Study

Affiliations

Nursing Complexity and Health Literacy as Determinants of Patient Outcomes: A Prospective One-Year Multicenter Cohort Study

Antonello Cocchieri et al. Nurs Rep. .

Abstract

Background/Objectives: Although nursing complexity and health literacy (HL) are critical determinants of patient outcomes, their combined impact on mortality, hospital re-admissions, and emergency department (ED) visits remains poorly understood. This study aims to measure nursing complexity and HL in hospitalized patients, examine their interaction, and analyze their impacts on mortality, hospital re-admissions, and ED visits over a one-year follow-up period. Methods: Adult patients from two hospital centers were enrolled, excluding those with stays under two days or cognitive impairments. Data were collected at baseline to assess nursing complexity (measured according to the number of nursing diagnoses assigned to patients within 24 h from hospital admission) and HL (assessed using the Single-Item Literacy Screener, SILS). Patients were followed during a 12-month follow-up period to track mortality, hospital re-admissions, and ED visits. Latent class analysis classified patients into distinct nursing complexity and HL profiles. Survival analyses and Cox proportional hazard models were used to evaluate the relationships between variables. Results: At baseline, among the 2667 enrolled patients, 55.9% were classified as having high nursing complexity, and 32% had inadequate HL. High nursing complexity was associated with lower HL (r = 0.384; p < 0.001). During follow-up, 387 patients (14.5%) were lost. Of the remaining sample, mortality occurred in 8.3% of the patients, hospital re-admissions in 27.2%, and ED visits in 16.8%. Nursing complexity was significantly associated with higher mortality (HR: 1.84, adjusted HR: 1.81), but not with hospital re-admissions or ED visits. The patients with inadequate HL (32%) had increased risks of mortality (HR: 11.21, adjusted HR: 7.75), hospital re-admissions (HR: 3.61, adjusted HR: 3.58), and ED visits (HR: 20.78, adjusted HR: 14.45). The patients with both high nursing complexity and inadequate HL had the highest mortality risk and the lowest 12-month survival rate (75%; 95% CI: 71.1-79.1%; p < 0.001). Conclusions: This study demonstrates that both high nursing complexity and inadequate HL independently and jointly contribute to adverse patient outcomes. Interventions targeting HL and supporting patients with high nursing complexity could reduce risks, enhance care, and improve patient survival. While these findings underscore the critical role of both factors in patient outcomes, the limitations include this study's single-country setting and reliance on a single-item HL measure. Future research should validate these findings in broader healthcare contexts and integrate multidimensional HL assessments for a more comprehensive evaluation.

Keywords: emergency room visits; health literacy; nursing complexity; nursing diagnosis; patient outcome assessment; patient re-admission; survival.

Conflict of interest statement

The authors declare no conflicts of interest. The funders had no role in the design of this study; in the collection, analyses, or interpretation of data; in the writing of this manuscript; or in the decision to publish the results.

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Observational Study
. 2025 May 7:27:e67830.
doi: 10.2196/67830.

Comparing Artificial Intelligence-Generated and Clinician-Created Personalized Self-Management Guidance for Patients With Knee Osteoarthritis: Blinded Observational Study

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Free article
Observational Study

Comparing Artificial Intelligence-Generated and Clinician-Created Personalized Self-Management Guidance for Patients With Knee Osteoarthritis: Blinded Observational Study

Kai Du et al. J Med Internet Res. .
Free article

Abstract

Background: Knee osteoarthritis is a prevalent, chronic musculoskeletal disorder that impairs mobility and quality of life. Personalized patient education aims to improve self-management and adherence; yet, its delivery is often limited by time constraints, clinician workload, and the heterogeneity of patient needs. Recent advances in large language models offer potential solutions. GPT-4 (OpenAI), distinguished by its long-context reasoning and adoption in clinical artificial intelligence research, emerged as a leading candidate for personalized health communication. However, its application in generating condition-specific educational guidance remains underexplored, and concerns about misinformation, personalization limits, and ethical oversight remain.

Objective: We evaluated GPT-4's ability to generate individualized self-management guidance for patients with knee osteoarthritis in comparison with clinician-created content.

Methods: This 2-phase, double-blind, observational study used data from 50 patients previously enrolled in a registered randomized trial. In phase 1, 2 orthopedic clinicians each generated personalized education materials for 25 patient profiles using anonymized clinical data, including history, symptoms, and lifestyle. In phase 2, the same datasets were processed by GPT-4 using standardized prompts. All content was anonymized and evaluated by 2 independent, blinded clinical experts using validated scoring systems. Evaluation criteria included efficiency, readability (Flesch-Kincaid, Gunning Fog, Coleman-Liau, and Simple Measure of Gobbledygook), accuracy, personalization, and comprehensiveness and safety. Disagreements between reviewers were resolved through consensus or third-party adjudication.

Results: GPT-4 outperformed clinicians in content generation speed (530.03 vs 37.29 words per min, P<.001). Readability was better on the Flesch-Kincaid (mean 11.56, SD 1.08 vs mean 12.67 SD 0.95), Gunning Fog (mean 12.47, SD 1.36 vs mean 14.56, SD 0.93), and Simple Measure of Gobbledygook (mean 13.33, SD 1.00 vs mean 13.81 SD 0.69) indices (all P<.001), though GPT-4 scored slightly higher on the Coleman-Liau Index (mean 15.90, SD 1.03 vs mean 15.15, SD 0.91). GPT-4 also outperformed clinicians in accuracy (mean 5.31, SD 1.73 vs mean 4.76, SD 1.10; P=.05, personalization (mean 54.32, SD 6.21 vs mean 33.20, SD 5.40; P<.001), comprehensiveness (mean 51.74, SD 6.47 vs mean 35.26, SD 6.66; P<.001), and safety (median 61, IQR 58-66 vs median 50, IQR 47-55.25; P<.001).

Conclusions: GPT-4 could generate personalized self-management guidance for knee osteoarthritis with greater efficiency, accuracy, personalization, comprehensiveness, and safety than clinician-generated content, as assessed using standardized, guideline-aligned evaluation frameworks. These findings underscore the potential of large language models to support scalable, high-quality patient education in chronic disease management. The observed lexical complexity suggests the need to refine outputs for populations with limited health literacy. As an exploratory, single-center study, these results warrant confirmation in larger, multicenter cohorts with diverse demographic profiles. Future implementation should be guided by ethical and operational safeguards, including data privacy, transparency, and the delineation of clinical responsibility. Hybrid models integrating artificial intelligence-generated content with clinician oversight may offer a pragmatic path forward.

Keywords: AI-generated; ChatGPT; GPT-4; LLMs; artificial intelligence; artificial intelligence in health care; knee; knee osteoarthritis; large language models; observational study; orthopedics; osteoarthritis; patient education; personalized medicine; self-management.

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. 2025 May 2;71(3):e20240935.
doi: 10.1590/1806-9282.20240935. eCollection 2025.

Approach to external cephalic version through social media: experience from a tertiary center in Brazil

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Approach to external cephalic version through social media: experience from a tertiary center in Brazil

Suellyn de Pinho Alves et al. Rev Assoc Med Bras (1992). .

Abstract

Objective: The aim of this study was to develop a communication and health education page on external cephalic version through the social media Instagram and, second, to assess the degree of patients' prior understanding of the external cephalic version procedure.

Methods: We conducted a prospective cohort study on 133 singleton pregnancies (until 41 weeks of gestation), for which an online questionnaire (Google Forms) was applied on the social media Instagram, with four sections. The questionnaire was applied between January 2022 and December 2023. Before the intervention (reading the content displayed on Instagram), sections 1, 2, and 3 were applied, and after reading, section 4. Pregnant women of any gestational age who received prenatal care at our service were included. Patients<14 years of age and those who could not read were excluded.

Results: A statistically significant difference was found after reading the content made available on Instagram, with a positive evolution after reading (p<0.001). Of this sample, 100% felt that knowledge about the external cephalic version should reach the major population of pregnant women, 131 (98.50%) opined that they would talk to other pregnant women about it, and 113 (84.96%) said that they would perform the procedure if they had indications for it.

Conclusion: This study provided a comprehensive overview of pregnant women's knowledge about external cephalic version. Through the results obtained, it is possible to observe the evolution of pregnant women's knowledge about external cephalic version after reading the content available on Instagram. In addition, the pregnant women expressed a strong desire to share information about the external cephalic version with other pregnant women.

Conflict of interest statement

Conflicts of interest: the authors declare there is no conflicts of interest.

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. 2025 May 2:33:e4494.
doi: 10.1590/1518-8345.7395.4494. eCollection 2025.

Sociodemographic and clinical characteristics associated with health literacy in people hospitalized for chronic diseases

[Article in English, Portuguese, Spanish]
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Sociodemographic and clinical characteristics associated with health literacy in people hospitalized for chronic diseases

[Article in English, Portuguese, Spanish]
Francini de Oliveira Rodrigues et al. Rev Lat Am Enfermagem. .

Abstract

to identify the association between health literacy and sociodemographic and clinical variables of hospitalized patients in people hospitalized with chronic diseases.

this was a cross-sectional study of patients with chronic illnesses admitted to a general hospital. A sociodemographic/clinical questionnaire and the Health Literacy Questionnaire comprising nine scales measured by scores, were used, with descriptive and inferential data analysis.

Social Support for Health was associated with the level of primary education (p=0.009). Understanding and Support from Health Professionals were related to the length of chronic illness (p=0.044). Evaluation of Health Information was associated with age (p=0.001), being able to read (p=0.010) and write (p=0.032). Navigating the Health System was also associated with age (p=0.018), as was the Ability to Find Good Health Information (p=0.002) and being able to read (p=0.010), and Understanding Health Information Well Enough to Know What to Do was associated with age (p=0.001) and being able to write (p=0.010).

schooling, age group, length of time with a chronic illness, and being able to read and write interfere with health literacy. This highlights the need for personalized strategies that take these variables into account in order to improve health literacy in hospitalized populations.

identificar a associação do letramento em saúde com as variáveis sociodemográficas e clínicas de pacientes hospitalizados com doenças crônicas.

estudo transversal, realizado com pacientes com doenças crônicas, internadas em um hospital geral. Utilizaram-se um questionário sociodemográfico/clínico e o Health Literacy Questionnaire, composto por nove escalas, mensuradas por escores, com a análise dos dados descritiva e inferencial.

o Suporte Social Para a Saúde foi associado ao nível de escolaridade fundamental (p=0,009). Compreensão e Apoio dos Profissionais de Saúde foram relacionados ao tempo de doença crônica (p=0,044). A Avaliação das Informações de Saúde mostrou-se associada à faixa etária (p=0,001), saber ler (p=0,010) e escrever (p=0,032). Navegar no Sistema de Saúde também esteve relacionado à faixa etária (p=0,018), assim como a Capacidade de Encontrar Boas Informações de Saúde (p=0,002), e saber ler (p=0,010), e Compreender as Informações de Saúde bem o Suficiente para Saber o que Fazer esteve associada à faixa etária (p=0,001) e saber escrever (p=0,010).

escolaridade, faixa etária, tempo de doença crônica, saber ler e escrever, interferem no letramento em saúde. Isso destaca a necessidade de estratégias personalizadas que levem em consideração essas variáveis para melhorar o letramento em saúde em populações com doenças crônicas hospitalizadas.

Destaques:: (1) Primeiro estudo brasileiro que avaliou o letramento em saúde de pessoas com DCNT. (2) Potencialidades: capacidade de interação, navegar no sistema e suporte social. (3) Fragilidades: avaliação das informações de saúde e capacidade de encontrá-las. (4) Idade, escolaridade, saber ler e escrever interferem no letramento em saúde.

identificar la asociación entre alfabetización en salud y las variables sociodemográficas y clínicas de pacientes hospitalizados con enfermedades crónicas.

estudio transversal, realizado con pacientes con enfermedades crónicas ingresadas en un hospital general. Se utilizó un cuestionario sociodemográfico/clínico y el Health Literacy Questionnaire, compuesto por nueve escalas, medidas por puntajes. Análisis descriptivo e inferencial de los datos.

el apoyo social a la salud se asoció con el nivel de educación primaria (p=0,009). La comprensión y el apoyo de los profesionales de la salud se relacionaron con la duración de la enfermedad crónica (p=0,044). La evaluación de la información de salud se asoció con la franja etaria (p=0,001), saber leer (p=0,010) y escribir (p=0,032). Navegar por el sistema de salud también estuvo relacionado con la franja etaria (p=0,018), al igual que la capacidad para encontrar buena información de salud (p=0,002), saber leer (p=0,010) y comprender la información de salud lo suficientemente bien como para saber qué hacer se asoció con la franja etaria (p=0,001) y saber escribir (p=0,010).

la educación, la franja etaria, la duración de la enfermedad crónica y el saber leer y escribir interfieren en la alfabetización en salud. Esto destaca que es necesario desarrollar estrategias personalizadas que consideren esas variables para mejorar la alfabetización en salud de la población hospitalizada.

Destacados:: (1) Primer estudio brasileño que evaluó la alfabetización en salud de personas con ECNT. (2) Potencialidades: Capacidad para interactuar, navegar en el sistema y apoyo social. (3) Debilidades: Evaluación de la información de salud y capacidad para encontrarla.(4) La edad, la educación y el saber leer y escribir interfieren en la alfabetización en salud.

Conflict of interest statement

Conflict of interest: the authors have declared that there is no conflict of interest.

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. 2025 Apr 30;11(1):24-25.
doi: 10.32481/djph.2025.04.06. eCollection 2025 Apr.

Global Health Literacy: Delaware and Beyond!

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Global Health Literacy: Delaware and Beyond!

Greg O'Neill. Dela J Public Health. .
No abstract available
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Comparative Study
. 2025 Apr 22:16:1559265.
doi: 10.3389/fendo.2025.1559265. eCollection 2025.

Comparison of artificial intelligence-generated and physician-generated patient education materials on early diabetic kidney disease

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Comparative Study

Comparison of artificial intelligence-generated and physician-generated patient education materials on early diabetic kidney disease

Miaomiao Cheng et al. Front Endocrinol (Lausanne). .

Abstract

Background: Diabetic kidney disease (DKD) is a common and serious complication of diabetes mellitus and has become the most important cause of end-stage renal disease (ESRD). In light of the rising prevalence of diabetes, there is a growing imperative for the early detection and intervention of DKD. With the rapid development of artificial intelligence (AI) technologies, its potential applications in patient education are receiving increasing attention, especially large language models (LLMs). The aim of this study was to evaluate the quality of LLMs-generated patient education materials (PEMs) for early DKD and to explore its feasibility in patient education.

Methods: Four LLMs (ERNIE Bot 4.0, GPT-4o, ChatGLM4, and ChatGPT-o1) were selected for this study to generate PEMs. Among them, ERNIE Bot 4.0, GPT-4o, and ChatGLM4 generated 2 versions of PEMs based on American Diabetes Association(ADA) guidelines and without ADA guidelines, respectively. ChatGPT-o1 only generated a PEM without ADA guidelines. An experienced physician wrote a PEM based on ADA guidelines. All materials were assessed using a Likert scale which covered the dimensions of accuracy, completeness, safety, and patient comprehensibility. A total of 7 medical experts (including nephrologists and endocrinologists) and 50 diabetic patients were invited to evaluate the study. We recorded basic information on the patient evaluators.

Results: Experts evaluated PEMs from ERNIE Bot 4.0, GPT-4o, ChatGLM4, and ChatGPT-o1, plus physician-sourced PEM. Results showed ERNIE Bot 4.0's non-guideline PEM and physician-sourced PEM were the top two. Patient assessments of the 2 top-scoring PEMs found that the ERNIE Bot 4.0's non-guideline PEM performed as well as, if not slightly better than, the physician-sourced PEM in terms of patient comprehensibility, completeness, and safety. In addition, the non-guideline-based PEM was preferred for patients with a history of diabetes longer than 5 years and for patients with proteinuria. Surprisingly, GPT-4o and ChatGLM4's non-guideline PEMs outperformed guideline-based ones.

Conclusion: The LLMs-sourced PEMs, especially the ERNIE Bot 4.0's non-guideline PEM for early DKD, performed comparably to the physician-sourced PEM in terms of accuracy, completeness, safety, and patient comprehensibility, and exerted a high degree of feasibility. AI may show the potential for broader applications in patient education in the near future.

Keywords: artificial intelligence; diabetes; diabetic kidney disease; large language models; patient education.

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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. 2025 Jan-Mar;16(1):45-50.
doi: 10.4103/jmh.jmh_182_24. Epub 2025 Apr 5.

Evaluating Accuracy and Readability of Responses to Midlife Health Questions: A Comparative Analysis of Six Large Language Model Chatbots

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Evaluating Accuracy and Readability of Responses to Midlife Health Questions: A Comparative Analysis of Six Large Language Model Chatbots

Himel Mondal et al. J Midlife Health. 2025 Jan-Mar.

Abstract

Background: The use of large language model (LLM) chatbots in health-related queries is growing due to their convenience and accessibility. However, concerns about the accuracy and readability of their information persist. Many individuals, including patients and healthy adults, may rely on chatbots for midlife health queries instead of consulting a doctor. In this context, we evaluated the accuracy and readability of responses from six LLM chatbots to midlife health questions for men and women.

Methods: Twenty questions on midlife health were asked to six different LLM chatbots - ChatGPT, Claude, Copilot, Gemini, Meta artificial intelligence (AI), and Perplexity. Each chatbot's responses were collected and evaluated for accuracy, relevancy, fluency, and coherence by three independent expert physicians. An overall score was also calculated by taking the average of four criteria. In addition, readability was analyzed using the Flesch-Kincaid Grade Level, to determine how easily the information could be understood by the general population.

Results: In terms of fluency, Perplexity scored the highest (4.3 ± 1.78), coherence was highest for Meta AI (4.26 ± 0.16), accuracy of responses was highest for Meta AI, and relevancy score was highest for Meta AI (4.35 ± 0.24). Overall, Meta AI scored the highest (4.28 ± 0.16), followed by ChatGPT (4.22 ± 0.21), whereas Copilot had the lowest score (3.72 ± 0.19) (P < 0.0001). Perplexity showed the highest score of 41.24 ± 10.57 in readability and lowest in grade level (11.11 ± 1.93), meaning its text is the easiest to read and requires a lower level of education.

Conclusion: LLM chatbots can answer midlife-related health questions with variable capabilities. Meta AI was found to be highest scoring chatbot for addressing men's and women's midlife health questions, whereas Perplexity offers high readability for accessible information. Hence, LLM chatbots can be used as educational tools for midlife health by selecting appropriate chatbots according to its capability.

Keywords: Artificial intelligence; chatbots; health education; large language models; midlife health; patient education; patient queries.

Conflict of interest statement

There are no conflicts of interest.

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. 2025 May 6;25(1):1669.
doi: 10.1186/s12889-025-22936-5.

Analysis of factors influencing delayed treatment seeking for dental caries in preschool children: a cross-sectional study

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Analysis of factors influencing delayed treatment seeking for dental caries in preschool children: a cross-sectional study

Jingsi Huang et al. BMC Public Health. .

Abstract

Objective: This study investigated the prevalence of treatment delays among preschoolers with dental caries, identified the associated influencing factors, and predicted the risk of delayed treatment. The findings of this study provide an evidence base for future interventions designed to reduce treatment delays in this population.

Methods: A convenience sample of 264 preschool children with dental caries and their parents who visited the paediatric dental department between October 2023 and May 2024 was surveyed. Data were collected using a general information questionnaire, a medical status questionnaire, the Children's Fear Survey Schedule-Dental Subscale, the Modified Version Dental Anxiety Scale, the Short-Form Health Literacy Dental Scale, and the Illness Perception Questionnaire Revised for Dental. Influencing factors were analysed using univariate analysis and binary logistic regression, whereas the risk of occurrence was predicted using the receiver operating characteristic (ROC) curve.

Results: The prevalence of delayed treatment among preschool children with dental caries was 71.21%, with an average delay of 117.5 days. Binary logistic regression analysis identified several independent factors significantly associated with delayed treatment (P < 0.05), including the primary caregiver, initial symptom recognition, children's dental fear, parental dental anxiety, and parental oral health literacy. Predictive analyses indicated that children's dental fear (AUC: 0.765, 95%CI: 0.707-0.823) and parental oral health literacy (AUC: 0.738, 95%CI: 0.673-0.802) demonstrated relatively high predictive values for delayed treatment.

Conclusion: Efforts to reduce delayed treatment should prioritise addressing children's dental fear and improving parental oral health literacy. Targeted and effective strategies in these areas may facilitate early prevention, diagnosis, and intervention, thereby minimising treatment delays, reducing disease burden, and promoting oral health among preschoolers.

Keywords: Cross-sectional study; Dental caries; Influencing factors; Preschoolers; Treatment delays.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: This study adhered strictly to the principles outlined in the Helsinki Declaration and received approval from the Ethics Committee of the School of Stomatology, China Medical University (Approval No. K2023-027). All participants, including children aged 3–6 and their parents, provided written informed consent after thoroughly understanding the research content and their rights. Participants were explicitly informed of their right to withdraw from the study at any time and were assured of anonymity throughout the research process. All research methods were conducted in strict compliance with relevant guidelines and regulations. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

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. 2025 May 6;25(1):1663.
doi: 10.1186/s12889-025-22892-0.

Acceptance of advance care planning among older adults in Mainland China: a national cross-sectional study

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Acceptance of advance care planning among older adults in Mainland China: a national cross-sectional study

Yisong Yao et al. BMC Public Health. .

Abstract

Background: Acceptance of advance care planning (ACP) among older adults is important for the promotion of ACP. It is of great importance to explore the acceptance of ACP and associated influencing factors among older adults in China based on the health ecology model (HEM).

Methods: Based on a national cross-sectional study in 2022, 4,180 older adults were included. Stepwise linear regression was used to analyze factors associated with acceptance of ACP using SPSS 26.0, based on the HEM. Acceptance scores were calculated based on a self-assessment visual analog scale (range, 0 ~ 100, with higher scores indicating higher acceptance of ACP).

Results: 50.05% (2,092) of 4,180 participants were female. The median acceptance of ACP score was 64, and the range was (49, 81). In addition, the study found higher well-being index (β = 0.086; 95% CI, 0.199 to 0.535; P < 0.001) and health literacy (β = 0.054; 95% CI, 0.07 to 0.423; P = 0.006) scores, broader media use behaviors (β = 0.064; 95% CI, 0.127 to 0.419; P < 0.001), and a higher per capita monthly household income (β = 0.086; 95% CI, 1.827 to 3.825; P < 0.001) were associated with a higher acceptance of ACP, while participants with higher depression scores (β = -0.06; 95% CI, -0.435 to -0.129; P < 0.001), larger social network (β = -0.054; 95% CI, -3.289 to -0.937; P < 0.001), and health insurance (β = -0.04; 95% CI, -7.294 to -1.027; P = 0.008) demonstrated a lower acceptance of ACP.

Conclusions: For the first time, this study revealed basic personal information, economic status, media use, social networks, health knowledge, and mental health as the main factors associated with acceptance of ACP among older adults in mainland China. These findings were of great significant for enhancing healthcare quality and the overall quality of life for older adults in China.

Keywords: Acceptance of Advance Care Planning; Health Ecology Model; Health literacy; Media Use; Older Adults in Mainland China.

Conflict of interest statement

Declarations. Ethics approval and consent to participate: The Ethics Research Committee of the Health Culture Research Center of Shaanxi approved this study (No. JKWH-2022–02). All participants provided informed consent before data collection, and all data were kept strictly confidential. All methods in our study were performed following the guidelines and regulations of the Declaration of Helsinki. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

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. 2025 May 6;15(1):15818.
doi: 10.1038/s41598-025-00745-5.

The effects of sexuality education program on sexual quality of life among patients following coronary artery bypass graft

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The effects of sexuality education program on sexual quality of life among patients following coronary artery bypass graft

Arthit Oeychanai et al. Sci Rep. .

Abstract

Patients who undergo coronary artery bypass grafting surgery rarely receive information or have discussions regarding sexual quality of life with their healthcare providers. This quasi-experimental study aimed to assess the effectiveness of sexuality education programs on sexual quality of life following coronary artery bypass grafting surgery in Thailand. The experimental group, consisting of 30 participants, received sexual education, while a control group of 30 participants received routine care. The primary outcome measured was sexual quality of life, evaluated both before and after the intervention. An independent samples t-test was utilized to compare outcomes between the two groups, and a paired t-test was employed to assess changes within the intervention group. The results demonstrated a statistically significant difference in sexual quality of life between the groups (t = 3.47, p = 0.001). Moreover, the sexual quality of life score increased significantly in the intervention group (t = 4.52, p < 0.001), while no significant changes were observed in the control group (t = 0.41, p = 0.688). These findings underscore the positive impact of sexuality education programs on improving sexual quality of life following coronary artery bypass grafting. It is essential for healthcare providers to incorporate health education for patients prior to hospital discharge and to monitor sexual quality of life during follow-up visits.

Keywords: Coronary artery bypass; Health education; Quality of life; Sexual behavior.

Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests. Ethics approval: The study protocol was in accordance with the principles of the Declaration of Helsinki. Written informed consent was obtained from all patients before data collection, and this study received approval to certify full compliance by the Siriraj Institutional Review Board (COA No. Si 153/2021).

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. 2025 Apr 20;43(4):280-288.
doi: 10.3760/cma.j.cn121094-20240306-00087.

[Health literacy level and influencing factors of eight occupational groups in Gansu Province in 2022]

[Article in Chinese]
Affiliations

[Health literacy level and influencing factors of eight occupational groups in Gansu Province in 2022]

[Article in Chinese]
H Y Zhang et al. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. .

Abstract

Objective: To investigate the level of occupational health literacy (OHL) of key populations in Gansu Province in 2022, analyze the influencing factors, and provide a scientific basis for the formulation of health education measures for occupational populations. Methods: From April to December 2022, a stratified cluster random sampling method was adopted to select 11472 workers engaged in frontline jobs in 8 key industries across 86 counties and districts in Gansu Province as the research subjects. The "National Occupational Health Literacy Monitoring and Survey Personal Questionnaire" was used to investigate their OHL. The content includes basic demographic information and occupational health literacy level, and the chi-square test analysis was carried out by SPSS 23.0 software, and the influencing factors were analyzed by logistic regression analysis model. Results: In 2022, a total of 11 118 valid questionnaires were completed in Gansu Province, and the OHL level of key populations in Gansu Province was 48.3%. The OHL levels of occupational health legal knowledge, basic knowledge of occupational health protection, basic skills of occupational health protection and healthy working methods were 50.3%, 81.7%, 33.1% and 63.3%, respectively. In the eight key industries, the OHL level of workers from high to low is: ferrous and non-ferrous metal smelting and rolling processing industry (56.6%) , non-metallic mineral products industry (56.5%) , ferrous and non-ferrous metal mining and dressing industry (54.3%) , environmental sanitation industry (50.3%) , medical and health industry (49.9%) , education industry (40.9%) , transportation industry (40.4%) , and express delivery/takeaway delivery industry (23.3%) . The results of logistics regression analysis showed that gender, age, ethnicity, marital status, education level, average monthly income, nature and scale of employers, and length of service were the influencing factors of OHL level of front-line workers in eight industries in Gansu Province (all P<0.05) . Conclusion: In 2022, the OHL level of key populations in Gansu Province was 48.3%, which needs to be further improved. Occupational health publicity should be strengthened for low-income, low-educated, newly recruited, young and micro-enterprise occupational groups.

目的: 了解2022年甘肃省重点职业人群职业健康素养(OHL)水平,分析影响因素,为职业人群制定健康宣教措施提供科学依据。 方法: 2022年4至12月采用分层整群随机抽样法,以甘肃省86个县区的8个重点行业从事一线工作的11 472名劳动者为研究对象,共回收11 118份有效问卷,采用《全国重点人群职业健康素养监测调查个人问卷》对其OHL展开调查。内容包括人口学基本信息和职业健康素养水平,进行χ(2)检验分析,并采用logistic回归分析模型分析其影响因素。 结果: 本次研究中全省重点人群OHL水平为48.3%(5 372/11 118)。职业健康法律知识、职业健康保护基本知识、职业健康保护基本技能和健康工作方式四个维度OHL水平分别为50.3%、81.7%、33.1%、63.3%。8个重点行业领域,一线劳动者OHL水平由高到低依次为:黑色及有色金属冶炼和压延加工业(56.6%)、非金属矿物制品业(56.5%)、黑色及有色金属矿采选业(54.3%)、环境卫生业(50.3%)、医疗卫生业(49.9%)、教育业(40.9%)、交通运输业(40.4%)、快递/外卖配送业(23.3%)。logistics回归分析结果显示,性别、年龄、民族、婚姻状况、文化程度、平均月收入、用人单位性质和规模、在岗工龄是甘肃省8个行业一线劳动者OHL水平的影响因素(P<0.05)。 结论: 甘肃省重点人群OHL水平有待进一步提高,应加大对低收入、低学历、新入职、年轻及微型企业职业人群的职业健康宣传力度。.

Keywords: Health literacy; Influencing factors; Key industries; Occupational populations.

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Exploring the Scope of Melanoma Educational Content on Instagram

Alyssa Swearingen et al. J Drugs Dermatol. .

Abstract

Swearingen A, Olagun-Samuel C, Sikora M, et al. Exploring the scope of melanoma educational content on Instagram. J Drugs Dermatol. 2025;24(5):e34. doi:10.36849/JDD.8751.

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Comparative Study
. 2025 Jan 1;28(1):27-32.
doi: 10.4103/njcp.njcp_70_24. Epub 2025 Mar 17.

Rabies in Social Media Videos: Comparison of Instagram and YouTube

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Free article
Comparative Study

Rabies in Social Media Videos: Comparison of Instagram and YouTube

M F Baran et al. Niger J Clin Pract. .
Free article

Abstract

Objective: This study aims to elucidate the informational content related to post-exposure patient education for this disease, emphasizing the significance of social media platforms as sources of information. The goal is to uncover and compare the information available on various social media platforms.

Methodology: Searches were conducted on Instagram and YouTube using the search terms "Rabies," "Rabies disease," and "Rabies vaccine." A total of 274 videos were examined, with 150 from YouTube and 124 from Instagram. The content of the videos was assessed based on 10 criteria determined by researchers according to the National Rabies Prophylaxis Guidelines, and a scoring system was applied.

Results: Instagram videos had more exclusion criteria. When examined based on uploader characteristics, the number of healthcare professionals on Instagram was higher than on YouTube. For questions related to "What is rabies," "What are the symptoms in animals," and "How should pre-exposure prophylaxis be," Instagram videos received higher scores. Videos uploaded by healthcare professionals received higher scores in questions related to "What is rabies," "How does it spread to humans," "How should wound care be," "Pre-exposure prophylaxis," "Post-exposure prophylaxis," and total score compared to videos uploaded by other independent users.

Conclusion: A significant portion of the videos uploaded by various users on social media about rabies were found to be unrelated and lacking in informative content. It was observed that videos on Instagram were more informative compared to YouTube. Health professionals were found to provide more informative and directive content in videos related to rabies.

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. 2025 Mar-Apr;21(2):163-169.
doi: 10.5055/jom.0918.

Examining the effect of a Whole Health Primary Care Pain Education and Opioid Monitoring Program (PC-POP) at preventing opioid-induced constipation

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Examining the effect of a Whole Health Primary Care Pain Education and Opioid Monitoring Program (PC-POP) at preventing opioid-induced constipation

Taylor Hammack et al. J Opioid Manag. 2025 Mar-Apr.

Abstract

Objective: The prevention of opioid-induced constipation (OIC) in patients treated for chronic pain is important for an improved quality of life and prevention of complications. This study aims to determine whether the implementation of the Primary Care Pain Education and Opioid Monitoring Program (PC-POP) improved the management of OIC in patients receiving opioids for chronic noncancer pain. Design/measure: Pharmacy records regarding the presence of an appropriate laxative prescription, prescription fills, and laxative types were obtained. The primary outcome was the proportion of patients with an appropriate laxative prescription on file for the management of OIC.

Setting: This study was conducted in the Salt Lake City Veterans Affairs (VA) Medical Center's primary care setting.

Subjects: Patients aged 18 and older being treated with opioids for chronic noncancer pain >3 months who were enrolled in PC-POP and had attended at least two classes were compared to patients receiving standard primary care at a VA Medical Center.

Results: Of the 698 patients included, 39.2 percent of patients enrolled in PC-POP had a laxative prescription on file compared to 20.9 percent for patients receiving standard primary care from a VA provider. Presence of appropriate laxative prescription was significantly higher for the PC-POP group (p = <0.001).

Conclusion: PC-POP enrollment was associated with a significantly higher number of appropriate laxative prescription for the management of OIC. This study indicates that there is potential for improvement in prescribing practices to ensure patients receive appropriate laxatives to mitigate the impact of OIC. It also indicates that implementation of a similar program at other VA Medical Centers could improve OIC management in veterans receiving opioids for chronic noncancer pain.

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