Successful management of post-COVID-19 acanthamoebic encephalitis

Int J Infect Dis. 2021 Sep:110:226-228. doi: 10.1016/j.ijid.2021.07.046. Epub 2021 Jul 22.

Abstract

Acanthamoebic encephalitis is a rare and highly fatal disease that has no standard management protocol. Coronavirus disease 2019 (COVID-19) causes immune dysfunction and may predispose patients to this infection. The present study describes successful management of acanthamoebic encephalitis in a young male who recently recovered from COVID-19 using a combination of medical and surgical approaches. A combination of miltefosine with other agents with trophicidal and cysticidal activities should be used in the regimen. Surgical excision of the abscess should be undertaken whenever feasible.

Keywords: Acanthamoeba; COVID-19; acanthamoebic encephalitis; miltefosine.

Publication types

  • Case Reports

MeSH terms

  • COVID-19*
  • Encephalitis*
  • Humans
  • Male
  • SARS-CoV-2