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Microtubule cross-linking triggers the directional motility of kinesin-5.
Kapitein LC, Kwok BH, Weinger JS, Schmidt CF, Kapoor TM, Peterman EJ. Kapitein LC, et al. J Cell Biol. 2008 Aug 11;182(3):421-8. doi: 10.1083/jcb.200801145. Epub 2008 Aug 4. J Cell Biol. 2008. PMID: 18678707 Free PMC article.
Eg5's motility becomes directional when bound between two microtubules. ...This mechanism would increase energy and filament cross-linking efficiency....
Eg5's motility becomes directional when bound between two microtubules. ...This mechanism would increase energy …
Activation of mitotic kinesin by microtubule bundling.
Tomishige M. Tomishige M. J Cell Biol. 2008 Aug 11;182(3):417-9. doi: 10.1083/jcb.200807093. Epub 2008 Aug 4. J Cell Biol. 2008. PMID: 18678712 Free PMC article.
Kinesin-5 family members cross-link and slide parallel microtubules of opposite polarity, an activity that is essential for the formation of a bipolar spindle during mitosis. ...J. Cell Biol. 182:421-428) demonstrate that microtubule c
Kinesin-5 family members cross-link and slide parallel microtubules of opposite polarity, an activity that is es
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