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Page 1
Epidemiological characterisation of the first 785 SARS-CoV-2 Omicron variant cases in Denmark, December 2021.
Espenhain L, Funk T, Overvad M, Edslev SM, Fonager J, Ingham AC, Rasmussen M, Madsen SL, Espersen CH, Sieber RN, Stegger M, Gunalan V, Wilkowski B, Larsen NB, Legarth R, Cohen AS, Nielsen F, Lam JUH, Lavik KE, Karakis M, Spiess K, Marving E, Nielsen C, Wiid Svarrer C, Bybjerg-Grauholm J, Olsen SS, Jensen A, Krause TG, Müller L. Espenhain L, et al. Among authors: cohen as. Euro Surveill. 2021 Dec;26(50):2101146. doi: 10.2807/1560-7917.ES.2021.26.50.2101146. Euro Surveill. 2021. PMID: 34915977 Free PMC article.
Increased transmissibility of SARS-CoV-2 lineage B.1.1.7 by age and viral load.
Lyngse FP, Mølbak K, Skov RL, Christiansen LE, Mortensen LH, Albertsen M, Møller CH, Krause TG, Rasmussen M, Michaelsen TY, Voldstedlund M, Fonager J, Steenhard N; Danish Covid-19 Genome Consortium; Kirkeby CT. Lyngse FP, et al. Nat Commun. 2021 Dec 13;12(1):7251. doi: 10.1038/s41467-021-27202-x. Nat Commun. 2021. PMID: 34903718 Free PMC article.
Risk of hospitalisation associated with infection with SARS-CoV-2 omicron variant versus delta variant in Denmark: an observational cohort study.
Bager P, Wohlfahrt J, Bhatt S, Stegger M, Legarth R, Møller CH, Skov RL, Valentiner-Branth P, Voldstedlund M, Fischer TK, Simonsen L, Kirkby NS, Thomsen MK, Spiess K, Marving E, Larsen NB, Lillebaek T, Ullum H, Mølbak K, Krause TG; Omicron-Delta study group. Bager P, et al. Lancet Infect Dis. 2022 Jul;22(7):967-976. doi: 10.1016/S1473-3099(22)00154-2. Epub 2022 Apr 22. Lancet Infect Dis. 2022. PMID: 35468331 Free PMC article.
Household transmission of the SARS-CoV-2 Omicron variant in Denmark.
Lyngse FP, Mortensen LH, Denwood MJ, Christiansen LE, Møller CH, Skov RL, Spiess K, Fomsgaard A, Lassaunière R, Rasmussen M, Stegger M, Nielsen C, Sieber RN, Cohen AS, Møller FT, Overvad M, Mølbak K, Krause TG, Kirkeby CT. Lyngse FP, et al. Among authors: cohen as. Nat Commun. 2022 Sep 23;13(1):5573. doi: 10.1038/s41467-022-33328-3. Nat Commun. 2022. PMID: 36151099 Free PMC article.
A RT-qPCR system using a degenerate probe for specific identification and differentiation of SARS-CoV-2 Omicron (B.1.1.529) variants of concern.
Jessen R, Nielsen L, Larsen NB, Cohen AS, Gunalan V, Marving E, Alfaro-Núñez A, Polacek C; Danish COVID-19 Genome Consortium (DCGC); Fomsgaard A, Spiess K. Jessen R, et al. Among authors: cohen as. PLoS One. 2022 Oct 5;17(10):e0274889. doi: 10.1371/journal.pone.0274889. eCollection 2022. PLoS One. 2022. PMID: 36197885 Free PMC article.
Rapid and Flexible RT-qPCR Surveillance Platforms To Detect SARS-CoV-2 Mutations.
Spiess K, Gunalan V, Marving E, Nielsen SH, Jørgensen MGP, Fomsgaard AS, Nielsen L, Alfaro-Núñez A, Karst SM; Danish COVID-19 Genome Consortium (DCGC); Mortensen S, Rasmussen M, Lassaunière R, Rosenstierne MW, Polacek C, Fonager J, Cohen AS, Nielsen C, Fomsgaard A. Spiess K, et al. Among authors: cohen as. Microbiol Spectr. 2023 Feb 14;11(1):e0359122. doi: 10.1128/spectrum.03591-22. Epub 2023 Jan 9. Microbiol Spectr. 2023. PMID: 36625603 Free PMC article.
First cases of SARS-CoV-2 BA.2.86 in Denmark, 2023.
Rasmussen M, Møller FT, Gunalan V, Baig S, Bennedbæk M, Christiansen LE, Cohen AS, Ellegaard K, Fomsgaard A, Franck KT, Larsen NB, Larsen TG, Lassaunière R, Polacek C, Qvesel AG, Sieber RN, Rasmussen LD, Stegger M, Spiess K, Tang ME, Vestergaard LS, Andersen TE, Hoegh SV, Pedersen RM, Skov MN, Steinke K, Sydenham TV, Hoppe M, Nielsen L, Krause TG, Ullum H, Jokelainen P. Rasmussen M, et al. Among authors: cohen as. Euro Surveill. 2023 Sep;28(36):2300460. doi: 10.2807/1560-7917.ES.2023.28.36.2300460. Euro Surveill. 2023. PMID: 37676147 Free PMC article.
Neonatal metabolome of caesarean section and risk of childhood asthma.
Gürdeniz G, Ernst M, Rago D, Kim M, Courraud J, Stokholm J, Bønnelykke K, Björkbom A, Trivedi U, Sørensen SJ, Brix S, Hougaard D, Rasmussen M, Cohen AS, Bisgaard H, Chawes B. Gürdeniz G, et al. Among authors: cohen as. Eur Respir J. 2022 Jun 23;59(6):2102406. doi: 10.1183/13993003.02406-2021. Print 2022 Jun. Eur Respir J. 2022. PMID: 34887324 Free article.
A nationwide analytical and clinical evaluation of 44 rapid antigen tests for SARS-CoV-2 compared to RT-qPCR.
Schneider UV, Forsberg MW, Leineweber TD, Jensen CB, Ghathian K, Agergaard CN, Mortensen KK, Cohen A, Jørgensen CS, Larsen H, Hansen MB, Saleme U, Koch A, Kirkby NS, Kallemose T, Schaadt ML, Jensen FH, Jørgensen RL, Ma CMG, Steenhard N, Knudsen JD, Lisby JG; National Danish RAT testing group. Schneider UV, et al. J Clin Virol. 2022 Aug;153:105214. doi: 10.1016/j.jcv.2022.105214. Epub 2022 Jun 8. J Clin Virol. 2022. PMID: 35738151 Free PMC article.
Furan fatty acid metabolite in newborns predicts risk of asthma.
Gürdeniz G, Kim M, Brustad N, Ernst M, Russo F, Stokholm J, Bønnelykke K, Hougaard D, Rasmussen M, Cohen A, Chawes B. Gürdeniz G, et al. Allergy. 2023 Feb;78(2):429-438. doi: 10.1111/all.15554. Epub 2022 Oct 27. Allergy. 2023. PMID: 36254396 Clinical Trial.
Vitamin D status and severity of COVID-19.
Nielsen NM, Junker TG, Boelt SG, Cohen AS, Munger KL, Stenager E, Ascherio A, Boding L, Hviid A. Nielsen NM, et al. Among authors: cohen as. Sci Rep. 2022 Nov 17;12(1):19823. doi: 10.1038/s41598-022-21513-9. Sci Rep. 2022. PMID: 36396686 Free PMC article.
Development and validation of a vitamin D status prediction model in Danish pregnant women: a study of the Danish National Birth Cohort.
Bjørn Jensen C, Thorne-Lyman AL, Vadgård Hansen L, Strøm M, Odgaard Nielsen N, Cohen A, Olsen SF. Bjørn Jensen C, et al. PLoS One. 2013;8(1):e53059. doi: 10.1371/journal.pone.0053059. Epub 2013 Jan 9. PLoS One. 2013. PMID: 23326380 Free PMC article.
Vitamin D has been hypothesized to reduce risk of pregnancy complications such as preeclampsia, gestational diabetes mellitus, and preterm delivery. However, many of these outcomes are rare and require a large sample size to study, representing a challenge for cohorts with …
Vitamin D has been hypothesized to reduce risk of pregnancy complications such as preeclampsia, gestational diabetes mellitus, and pr …
Combined nasal- and oropharyngeal self-swab provides equivalent performance compared to professionally collected oropharyngeal swabs in detecting SARS-CoV-2 in a real-life setting.
Hørlyck S, Nielsen SH, Gress T, Schneider U, Martel CJ, Steenhard N, Gredal NT, Mortensen S, Cohen AS. Hørlyck S, et al. Among authors: cohen as. J Virol Methods. 2023 Mar;313:114667. doi: 10.1016/j.jviromet.2022.114667. Epub 2022 Dec 23. J Virol Methods. 2023. PMID: 36572155 Free PMC article.
Convergent evidence linking neonatal vitamin D status and risk of neurodevelopmental disorders: a Danish case-cohort study.
Horsdal HT, Albiñana C, Zhu Z, Boelt SG, Borbye-Lorenzen N, Cohen AS, Skogstrand K, Melgaard L, MacSween NJ, Thorbek MJ, Plana-Ripoll O, Petersen LV, Bulik CM, B Rglum AD, Mors O, Nordentoft M, Werge T, Moen GH, D'Urso S, Wray NR, Vilhjálmsson BJ, Agerbo E, Pedersen CBC, Mortensen PB, McGrath JJ. Horsdal HT, et al. Among authors: cohen as. Lancet Psychiatry. 2025 Jun;12(6):410-420. doi: 10.1016/S2215-0366(25)00099-9. Lancet Psychiatry. 2025. PMID: 40379361
Lack of Association Between Maternal or Neonatal Vitamin D Status and Risk of Childhood Type 1 Diabetes: A Scandinavian Case-Cohort Study.
Thorsen SU, Mårild K, Olsen SF, Holst KK, Tapia G, Granström C, Halldorsson TI, Cohen AS, Haugen M, Lundqvist M, Skrivarhaug T, Njølstad PR, Joner G, Magnus P, Størdal K, Svensson J, Stene LC. Thorsen SU, et al. Among authors: cohen as. Am J Epidemiol. 2018 Jun 1;187(6):1174-1181. doi: 10.1093/aje/kwx361. Am J Epidemiol. 2018. PMID: 29186303 Free PMC article.
Biochemical screening of 504,049 newborns in Denmark, the Faroe Islands and Greenland--experience and development of a routine program for expanded newborn screening.
Lund AM, Hougaard DM, Simonsen H, Andresen BS, Christensen M, Dunø M, Skogstrand K, Olsen RK, Jensen UG, Cohen A, Larsen N, Saugmann-Jensen P, Gregersen N, Brandt NJ, Christensen E, Skovby F, Nørgaard-Pedersen B. Lund AM, et al. Mol Genet Metab. 2012 Nov;107(3):281-93. doi: 10.1016/j.ymgme.2012.06.006. Epub 2012 Jun 21. Mol Genet Metab. 2012. PMID: 22795865
Gestational age-dependent development of the neonatal metabolome.
Ernst M, Rogers S, Lausten-Thomsen U, Björkbom A, Laursen SS, Courraud J, Børglum A, Nordentoft M, Werge T, Mortensen PB, Hougaard DM, Cohen AS. Ernst M, et al. Among authors: cohen as. Pediatr Res. 2021 May;89(6):1396-1404. doi: 10.1038/s41390-020-01149-z. Epub 2020 Sep 17. Pediatr Res. 2021. PMID: 32942288
Evaluation of four laboratory-based high-throughput SARS-CoV-2 automated antigen tests compared to RT-PCR on nasal and oropharyngeal samples.
Leineweber TD, Ghathian K, Lisby JG, Friis-Hansen L, Afzal S, Ellermann-Eriksen S, Ma CMG, Cohen AS, Jørgensen RL, Hansen MB, Kamstrup PR, Larsen H, Steenhard N, Jensen CB, Kallemose T, Forsberg MW, Kirkby NS, Schneider UV. Leineweber TD, et al. Among authors: cohen as. J Clin Virol. 2023 Jul;164:105472. doi: 10.1016/j.jcv.2023.105472. Epub 2023 May 2. J Clin Virol. 2023. PMID: 37178678 Free PMC article.
Multi-omics to predict changes during cold pressor test.
Kogelman LJA, Ernst M, Falkenberg K, Mazzoni G, Courraud J, Lundgren LP, Laursen SS, Cohen A, Olesen J, Hansen TF. Kogelman LJA, et al. BMC Genomics. 2022 Nov 19;23(1):759. doi: 10.1186/s12864-022-08981-z. BMC Genomics. 2022. PMID: 36402977 Free PMC article.
Elevated fetal steroidogenic activity in autism.
Baron-Cohen S, Auyeung B, Nørgaard-Pedersen B, Hougaard DM, Abdallah MW, Melgaard L, Cohen AS, Chakrabarti B, Ruta L, Lombardo MV. Baron-Cohen S, et al. Among authors: cohen as. Mol Psychiatry. 2015 Mar;20(3):369-76. doi: 10.1038/mp.2014.48. Epub 2014 Jun 3. Mol Psychiatry. 2015. PMID: 24888361 Free PMC article.
The autism group showed elevations across all hormones on this latent generalized steroidogenic factor (Cohen's d=0.37, P=0.0009) and this elevation was uniform across ICD-10 diagnostic label. These results provide the first direct evidence of elevated fetal steroidogenic …
The autism group showed elevations across all hormones on this latent generalized steroidogenic factor (Cohen's d=0.37, P=0.0009) and …
Amniotic fluid phthalate levels and male fetal gonad function.
Jensen MS, Anand-Ivell R, Nørgaard-Pedersen B, Jönsson BA, Bonde JP, Hougaard DM, Cohen A, Lindh CH, Ivell R, Toft G. Jensen MS, et al. Epidemiology. 2015 Jan;26(1):91-9. doi: 10.1097/EDE.0000000000000198. Epidemiology. 2015. PMID: 25384265
Stability of Proteins in Dried Blood Spot Biobanks.
Björkesten J, Enroth S, Shen Q, Wik L, Hougaard DM, Cohen AS, Sörensen L, Giedraitis V, Ingelsson M, Larsson A, Kamali-Moghaddam M, Landegren U. Björkesten J, et al. Among authors: cohen as. Mol Cell Proteomics. 2017 Jul;16(7):1286-1296. doi: 10.1074/mcp.RA117.000015. Epub 2017 May 13. Mol Cell Proteomics. 2017. PMID: 28501802 Free PMC article.
Foetal oestrogens and autism.
Baron-Cohen S, Tsompanidis A, Auyeung B, Nørgaard-Pedersen B, Hougaard DM, Abdallah M, Cohen A, Pohl A. Baron-Cohen S, et al. Mol Psychiatry. 2020 Nov;25(11):2970-2978. doi: 10.1038/s41380-019-0454-9. Epub 2019 Jul 29. Mol Psychiatry. 2020. PMID: 31358906 Free PMC article.
Associations between vitamin D status and atherosclerosis among Inuit in Greenland.
Gjødesen CU, Jørgensen ME, Bjerregaard P, Dahl-Petersen IK, Larsen CVL, Noël M, Melbye M, Cohen AS, Lundqvist M, Hougaard DM, Helge JW, Nielsen NO. Gjødesen CU, et al. Among authors: cohen as. Atherosclerosis. 2018 Jan;268:145-151. doi: 10.1016/j.atherosclerosis.2017.11.028. Epub 2017 Dec 1. Atherosclerosis. 2018. PMID: 29227867
Resveratrol reduces the levels of circulating androgen precursors but has no effect on, testosterone, dihydrotestosterone, PSA levels or prostate volume. A 4-month randomised trial in middle-aged men.
Kjaer TN, Ornstrup MJ, Poulsen MM, Jørgensen JO, Hougaard DM, Cohen AS, Neghabat S, Richelsen B, Pedersen SB. Kjaer TN, et al. Among authors: cohen as. Prostate. 2015 Sep;75(12):1255-63. doi: 10.1002/pros.23006. Epub 2015 May 4. Prostate. 2015. PMID: 25939591 Clinical Trial.
Author Correction: Vitamin D status and severity of COVID-19.
Nielsen NM, Junker TG, Boelt SG, Cohen AS, Munger KL, Stenager E, Ascherio A, Boding L, Hviid A. Nielsen NM, et al. Among authors: cohen as. Sci Rep. 2023 Jan 31;13(1):1781. doi: 10.1038/s41598-023-28993-3. Sci Rep. 2023. PMID: 36720914 Free PMC article. No abstract available.
Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots.
Albiñana C, Zhu Z, Borbye-Lorenzen N, Boelt SG, Cohen AS, Skogstrand K, Wray NR, Revez JA, Privé F, Petersen LV, Bulik CM, Plana-Ripoll O, Musliner KL, Agerbo E, Børglum AD, Hougaard DM, Nordentoft M, Werge T, Mortensen PB, Vilhjálmsson BJ, McGrath JJ. Albiñana C, et al. Among authors: cohen as. Nat Commun. 2023 Feb 15;14(1):852. doi: 10.1038/s41467-023-36392-5. Nat Commun. 2023. PMID: 36792583 Free PMC article.
Publisher Correction: Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots.
Albiñana C, Zhu Z, Borbye-Lorenzen N, Boelt SG, Cohen AS, Skogstrand K, Wray NR, Revez JA, Privé F, Petersen LV, Bulik CM, Plana-Ripoll O, Musliner KL, Agerbo E, Børglum AD, Hougaard DM, Nordentoft M, Werge T, Mortensen PB, Vilhjálmsson BJ, McGrath JJ. Albiñana C, et al. Among authors: cohen as. Nat Commun. 2024 Feb 26;15(1):1741. doi: 10.1038/s41467-024-46199-7. Nat Commun. 2024. PMID: 38409298 Free PMC article. No abstract available.
Alcohol-related breast cancer in postmenopausal women - effect of CYP19A1, PPARG and PPARGC1A polymorphisms on female sex-hormone levels and interaction with alcohol consumption and NSAID usage in a nested case-control study and a randomised controlled trial.
Kopp TI, Jensen DM, Ravn-Haren G, Cohen A, Sommer HM, Dragsted LO, Tjonneland A, Hougaard DM, Vogel U. Kopp TI, et al. BMC Cancer. 2016 Apr 21;16:283. doi: 10.1186/s12885-016-2317-y. BMC Cancer. 2016. PMID: 27102200 Free PMC article. Clinical Trial.
Corrigendum to 'Plasma concentrations of long chain N-3 fatty acids in early and mid-pregnancy and risk of early preterm birth'.
Olsen SF, Halldorsson TI, Thorne-Lyman AL, Strøm M, Gørtz S, Granstrøm C, Nielsen PH, Wohlfahrt J, Lykke JA, Langhoff-Roos J, Cohen AS, Furtado JD, Giovannucci EL, Zhou W. Olsen SF, et al. Among authors: cohen as. EBioMedicine. 2020 Jan;51:102619. doi: 10.1016/j.ebiom.2019.102619. Epub 2020 Jan 9. EBioMedicine. 2020. PMID: 31927481 Free PMC article. No abstract available.
The association between neonatal vitamin D status and risk of schizophrenia.
Eyles DW, Trzaskowski M, Vinkhuyzen AAE, Mattheisen M, Meier S, Gooch H, Anggono V, Cui X, Tan MC, Burne THJ, Jang SE, Kvaskoff D, Hougaard DM, Nørgaard-Pedersen B, Cohen A, Agerbo E, Pedersen CB, Børglum AD, Mors O, Sah P, Wray NR, Mortensen PB, McGrath JJ. Eyles DW, et al. Sci Rep. 2018 Dec 6;8(1):17692. doi: 10.1038/s41598-018-35418-z. Sci Rep. 2018. PMID: 30523285 Free PMC article.
Is there a correlation between androgens and sexual desire in women?
Wåhlin-Jacobsen S, Pedersen AT, Kristensen E, Laessøe NC, Lundqvist M, Cohen AS, Hougaard DM, Giraldi A. Wåhlin-Jacobsen S, et al. Among authors: cohen as. J Sex Med. 2015 Feb;12(2):358-73. doi: 10.1111/jsm.12774. Epub 2014 Dec 5. J Sex Med. 2015. PMID: 25475395
Characterization of CTNND2-related neurodevelopmental disease, phenotype-genotype spectrum and WNT dynamics in early neurogenesis.
Shahsavani M, Wincent J, Reiter R, Soltysova A, Schuy J, Helgadottir HT, Eisfeldt J, Ek M, Ficek A, Druschke L, Kusikova K, Hsieh TC, Krichhoff A, Krawitz P, Li JM, Webersinke G, Gorokhova S, Missirian C, Riccardi F, Pavinato L, Brusco A, Mandrile G, Trajkova S, Pintus F, Gagachovska B, Waisfisz Q, van Hagen A, Bedoukian E, Izumi K, Granger L, Petersen A, Oegema R, Huibers M, Demurger F, Brischoux-Boucher E, Julia S, Banneau G, Zavala MJ, Lagos C, Repetto GM, Jouret G, Kentros C, Ganapathi M, Chung WK, May H, Hiatt SM, Kelley WV, Förster A, Olfe L, Shillington A, Dauriat B, Mercier S, Cogné B, Engel C, Dahlen E, Rosenberger G, Sauvigny T, Abdallah HH, Courtin T, Stray-Pedersen A, Bernat JA, Paolillo VK, Viso FD, Alaimo JT, Thiffault I, Farrow EG, Cohen ASA, Weis S, Duba HC, Nordgren A, Falk A, Weis D, Lindstrand A. Shahsavani M, et al. Among authors: cohen asa. Res Sq [Preprint]. 2025 Dec 30:rs.3.rs-8224288. doi: 10.21203/rs.3.rs-8224288/v1. Res Sq. 2025. PMID: 41502569 Free PMC article. Preprint.
Unveiling Undergraduate Research: Employing Ecological Momentary Assessment to Characterize and Compare Undergraduate Research Experiences.
Mendez YCM, Listyg BS, Mardones-Segovia C, Bowers B, Cotto KMC, Hilton L, Koscik I, Outlaw B, Portner S, Barekzi N, Fegley ME, Mayoral J, McDonald KK, Rogers KJH, Sonnenberg-Klein J, Ulrich PN, Johnsen K, Wang S, Cohen AS, Lugo JSR, Dolan EL. Mendez YCM, et al. Among authors: cohen as. CBE Life Sci Educ. 2025 Dec 1;24(4):ar49. doi: 10.1187/cbe.24-11-0271. CBE Life Sci Educ. 2025. PMID: 41296874 Free PMC article.
One-Sided Matching Portal (OSMP): A Tool to Facilitate Rare Disease Patient Matchmaking.
Osmond M, Price EM, Buske OJ, Frew M, Couse M, Hartley T, Klamann C, Le HGBH, Xu J, So D, Jain A, Lu K, Mo K, Wyllie H, Wall E, Driver HG, Cheung WA, Cohen ASA, Farrow EG, Thiffault I, Consortium CRC, Turinsky AL, Pastinen T, Brudno M, Boycott KM. Osmond M, et al. Among authors: cohen asa. Hum Mutat. 2025 Oct 8;2025:5941599. doi: 10.1155/humu/5941599. eCollection 2025. Hum Mutat. 2025. PMID: 41103356 Free PMC article.
Clinical Long-Read Sequencing Test for Genetic Disease Diagnosis.
Thiffault I, Farrow E, Barrett C, Scott M, Ross A, Means JC, Cheung WA, Johnson AF, Koseva B, McLennan R, Grundberg E, Bi C, Schwendinger-Schreck C, Yoo B, Johnston JJ, Del Viso F, Paolillo V, Herriges J, Zhang L, Gibson M, Cohen ASA, Alaimo J, Saunders CJ, Pastinen T. Thiffault I, et al. JAMA Pediatr. 2025 Dec 1;179(12):1355-1357. doi: 10.1001/jamapediatrics.2025.3320. JAMA Pediatr. 2025. PMID: 40982260 Free PMC article.
Androgens mediate sexual dimorphism in Pilarowski-Bjornsson Syndrome.
Anderson KJ, Thorolfsdottir ET, Nodelman IM, Halldorsdottir ST, Benonisdottir S, Alghamdi M, Almontashiri N, Barry BJ, Begemann M, Britton JF, Burke S, Cogne B, Cohen ASA, de Diego Boguñá C, Eichler EE, Engle EC, Fahrner JA, Faivre L, Fradin M, Fuhrmann N, Gao CW, Garg G, Grečmalová D, Grippa M, Harris JR, Hoekzema K, Hershkovitz T, Hubbard S, Janssens K, Jurgens JA, Kmoch S, Knopp C, Koptagel MA, Ladha FA, Lapunzina P, Lindau T, Meuwissen M, Minicucci A, Neuhaus E, Nizon M, Nosková L, Park K, Patel C, Pfundt R, Prasun P, Rahner N, Robin NH, Ronspies C, Roohi J, Rosenfeld J, Saenz M, Saunders C, Stark Z, Thiffault I, Thull S, Velasco D, Velmans C, Verseput J, Vitobello A, Wang T, Weiss K, Wentzensen IM, Pilarowski G, Eysteinsson T, Gillentine M, Stefánsson K, Helgason A, Bowman GD, Bjornsson HT. Anderson KJ, et al. medRxiv [Preprint]. 2025 May 7:2025.05.06.25326635. doi: 10.1101/2025.05.06.25326635. medRxiv. 2025. PMID: 40385454 Free PMC article. Preprint.
Results of the Phase I/II Study and Preliminary B-cell Gene Signature of Combined Inhibition of Glutamine Metabolism and EGFR in Colorectal Cancer.
Ciombor KK, Bae SW, Whisenant JG, Ayers GD, Sheng Q, Peterson TE, Smith GT, Lin K, Chowdhury S, Kanikarla Marie P, Sorokin A, Cohen AS, Goff LW, Cardin DB, Shen JP, Kopetz S, Eng C, Shyr Y, Berlin J, Manning HC. Ciombor KK, et al. Among authors: cohen as. Clin Cancer Res. 2025 Apr 14;31(8):1437-1448. doi: 10.1158/1078-0432.CCR-24-3133. Clin Cancer Res. 2025. PMID: 39927885 Free PMC article. Clinical Trial.
Assessing barriers to meditation in patients with substance use disorder.
Champagne-Langabeer T, Cohen AS, Lopez A, Bakos-Block C, Campbell A, Gopal B, Cardenas-Turanzas M, Poudel A, Ratcliff C, Malik A, Korupolu R. Champagne-Langabeer T, et al. Among authors: cohen as. Complement Ther Clin Pract. 2025 May;59:101957. doi: 10.1016/j.ctcp.2025.101957. Epub 2025 Jan 27. Complement Ther Clin Pract. 2025. PMID: 39919368
MARK2 variants cause autism spectrum disorder via the downregulation of WNT/β-catenin signaling pathway.
Gong M, Li J, Qin Z, Machado Bressan Wilke MV, Liu Y, Li Q, Liu H, Liang C, Morales-Rosado JA, Cohen ASA, Hughes SS, Sullivan BR, Waddell V, van den Boogaard MH, van Jaarsveld RH, van Binsbergen E, van Gassen KL, Wang T, Hiatt SM, Amaral MD, Kelley WV, Zhao J, Feng W, Ren C, Yu Y, Boczek NJ, Ferber MJ, Lahner C, Elliott S, Ruan Y, Mignot C, Keren B, Xie H, Wang X, Popp B, Zweier C, Piard J, Coubes C, Mau-Them FT, Safraou H, Innes AM, Gauthier J, Michaud JL, Koboldt DC, Sylvie O, Willems M, Tan WH, Cogne B, Rieubland C, Braun D, McLean SD, Platzer K, Zacher P, Oppermann H, Evenepoel L, Blanc P, El Khattabi L, Haque N, Dsouza NR, Zimmermann MT, Urrutia R, Klee EW, Shen Y, Du H, Rappaport L, Liu CM, Chen X. Gong M, et al. Am J Hum Genet. 2024 Nov 7;111(11):2392-2410. doi: 10.1016/j.ajhg.2024.09.006. Epub 2024 Oct 16. Am J Hum Genet. 2024. PMID: 39419027 Free PMC article.
Intraoperative Guidance of Pancreatic Cancer Resection Using a Toll-like Receptor 2-Targeted Fluorescence Molecular Imaging Agent.
Huynh AS, Cohen AS, Doligalski M, Casagni TJ, Moberg VE, Huang X, Morse J, Abrahams D, Lloyd MC, Centeno BA, Baldwin MK, McLaughlin ML, Vagner J, Morse DL. Huynh AS, et al. Among authors: cohen as. Cancer Res Commun. 2024 Nov 1;4(11):2877-2887. doi: 10.1158/2767-9764.CRC-24-0244. Cancer Res Commun. 2024. PMID: 39320054 Free PMC article.
Geometric deep learning of protein-DNA binding specificity.
Mitra R, Li J, Sagendorf JM, Jiang Y, Cohen AS, Chiu TP, Glasscock CJ, Rohs R. Mitra R, et al. Among authors: cohen as. Nat Methods. 2024 Sep;21(9):1674-1683. doi: 10.1038/s41592-024-02372-w. Epub 2024 Aug 5. Nat Methods. 2024. PMID: 39103447 Free PMC article.
A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3.
Paul MS, Michener SL, Pan H, Chan H, Pfliger JM, Rosenfeld JA, Lerma VC, Tran A, Longley MA, Lewis RA, Weisz-Hubshman M, Bekheirnia MR, Bekheirnia N, Massingham L, Zech M, Wagner M, Engels H, Cremer K, Mangold E, Peters S, Trautmann J, Perne C, Mester JL, Guillen Sacoto MJ, Person R, McDonnell PP, Cohen SR, Lusk L, Cohen ASA, Le Pichon JB, Pastinen T, Zhou D, Engleman K, Racine C, Faivre L, Moutton S, Denommé-Pichon AS, Koh HY, Poduri A, Bolton J, Knopp C, Julia Suh DS, Maier A, Toosi MB, Karimiani EG, Maroofian R, Schaefer GB, Ramakumaran V, Vasudevan P, Banos-Pinero B, Pagnamenta AT, Prasad C, Osmond M, Schuhmann S, Vasileiou G, Russ-Hall S, Scheffer IE, Carvill GL, Mefford H; Undiagnosed Diseases Network; Bacino CA, Lee BH, Chao 趙孝端 HT. Paul MS, et al. Among authors: cohen sr, cohen asa. Am J Hum Genet. 2024 Jun 6;111(6):1239. doi: 10.1016/j.ajhg.2024.04.022. Epub 2024 May 8. Am J Hum Genet. 2024. PMID: 38723631 Free PMC article. No abstract available.
A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3.
Paul MS, Michener SL, Pan H, Chan H, Pfliger JM, Rosenfeld JA, Lerma VC, Tran A, Longley MA, Lewis RA, Weisz-Hubshman M, Bekheirnia MR, Bekheirnia N, Massingham L, Zech M, Wagner M, Engels H, Cremer K, Mangold E, Peters S, Trautmann J, Perne C, Mester JL, Guillen Sacoto MJ, Person R, McDonnell PP, Cohen SR, Lusk L, Cohen ASA, Le Pichon JB, Pastinen T, Zhou D, Engleman K, Racine C, Faivre L, Moutton S, Denommé-Pichon AS, Koh HY, Poduri A, Bolton J, Knopp C, Julia Suh DS, Maier A, Toosi MB, Karimiani EG, Maroofian R, Schaefer GB, Ramakumaran V, Vasudevan P, Banos-Pinero B, Pagnamenta AT, Prasad C, Osmond M, Schuhmann S, Vasileiou G, Russ-Hall S, Scheffer IE, Carvill GL, Mefford H; Undiagnosed Diseases Network; Bacino CA, Lee BH, Chao HT. Paul MS, et al. Among authors: cohen sr, cohen asa. Am J Hum Genet. 2024 Apr 4;111(4):805. doi: 10.1016/j.ajhg.2024.03.009. Epub 2024 Mar 20. Am J Hum Genet. 2024. PMID: 38508193 Free PMC article. No abstract available.
Head Injury Treatment With Healthy and Advanced Dietary Supplements: A Pilot Randomized Controlled Trial of the Tolerability, Safety, and Efficacy of Branched Chain Amino Acids in the Treatment of Concussion in Adolescents and Young Adults.
Corwin DJ, Myers SR, Arbogast KB, Lim MM, Elliott JE, Metzger KB, LeRoux P, Elkind J, Metheny H, Berg J, Pettijohn K, Master CL, Kirschen MP, Cohen AS. Corwin DJ, et al. Among authors: cohen as. J Neurotrauma. 2024 Jun;41(11-12):1299-1309. doi: 10.1089/neu.2023.0433. Epub 2024 Apr 11. J Neurotrauma. 2024. PMID: 38468511 Free PMC article. Clinical Trial.
Complex trait associations in rare diseases and impacts on Mendelian variant interpretation.
Smail C, Ge B, Keever-Keigher MR, Schwendinger-Schreck C, Cheung W, Johnston JJ, Barrett C; Genomic Answers for Kids Consortium; Feldman K, Cohen ASA, Farrow EG, Thiffault I, Grundberg E, Pastinen T. Smail C, et al. medRxiv [Preprint]. 2024 Jan 11:2024.01.10.24301111. doi: 10.1101/2024.01.10.24301111. medRxiv. 2024. Update in: Nat Commun. 2024 Sep 18;15(1):8196. doi: 10.1038/s41467-024-52407-1. PMID: 38260377 Free PMC article. Updated. Preprint.
The use and timing of angioembolization in pediatric blunt liver and spleen injury.
Naiditch JA, Notrica DM, Sayrs LW, Linnaus M, Stottlemyre R, Garcia NM, Lawson KA, Cohen AS, Letton RW, Johnson J, Maxson RT, Eubanks JW 3rd, Ryan M, Alder A, Ponsky TA, St Peter SD, Bhatia AM, Leys CM. Naiditch JA, et al. Among authors: cohen as. J Trauma Acute Care Surg. 2024 Jun 1;96(6):915-920. doi: 10.1097/TA.0000000000004228. Epub 2024 Jan 9. J Trauma Acute Care Surg. 2024. PMID: 38189680
A syndromic neurodevelopmental disorder caused by rare variants in PPFIA3.
Paul MS, Michener SL, Pan H, Chan H, Pfliger JM, Rosenfeld JA, Lerma VC, Tran A, Longley MA, Lewis RA, Weisz-Hubshman M, Bekheirnia MR, Bekheirnia N, Massingham L, Zech M, Wagner M, Engels H, Cremer K, Mangold E, Peters S, Trautmann J, Mester JL, Guillen Sacoto MJ, Person R, McDonnell PP, Cohen SR, Lusk L, Cohen ASA, Le Pichon JB, Pastinen T, Zhou D, Engleman K, Racine C, Faivre L, Moutton S, Denommé-Pichon AS, Koh HY, Poduri A, Bolton J, Knopp C, Julia Suh DS, Maier A, Toosi MB, Karimiani EG, Maroofian R, Schaefer GB, Ramakumaran V, Vasudevan P, Prasad C, Osmond M, Schuhmann S, Vasileiou G, Russ-Hall S, Scheffer IE, Carvill GL, Mefford H; Undiagnosed Diseases Network; Bacino CA, Lee BH, Chao HT. Paul MS, et al. Among authors: cohen sr, cohen asa. Am J Hum Genet. 2024 Jan 4;111(1):96-118. doi: 10.1016/j.ajhg.2023.12.004. Am J Hum Genet. 2024. PMID: 38181735 Free PMC article.
Factors associated with COVID-19 vaccine uptake in a US/Mexico border community: demographics, previous influenza vaccination, and trusted sources of health information.
Lomeli A, Escoto AA, Reyes B, Burola MLM, Tinoco-Calvillo S, Villegas I, Cohen AS, Laurent LC, Salgin L, Stadnick NA, Rabin B, Seifert M. Lomeli A, et al. Among authors: cohen as. Front Public Health. 2023 Jul 27;11:1163617. doi: 10.3389/fpubh.2023.1163617. eCollection 2023. Front Public Health. 2023. PMID: 37575117 Free PMC article.
The landscape of reported VUS in multi-gene panel and genomic testing: Time for a change.
Rehm HL, Alaimo JT, Aradhya S, Bayrak-Toydemir P, Best H, Brandon R, Buchan JG, Chao EC, Chen E, Clifford J, Cohen ASA, Conlin LK, Das S, Davis KW, Del Gaudio D, Del Viso F, DiVincenzo C, Eisenberg M, Guidugli L, Hammer MB, Harrison SM, Hatchell KE, Dyer LH, Hoang LU, Holt JM, Jobanputra V, Karbassi ID, Kearney HM, Kelly MA, Kelly JM, Kluge ML, Komala T, Kruszka P, Lau L, Lebo MS, Marshall CR, McKnight D, McWalter K, Meng Y, Nagan N, Neckelmann CS, Neerman N, Niu Z, Paolillo VK, Paolucci SA, Perry D, Pesaran T, Radtke K, Rasmussen KJ, Retterer K, Saunders CJ, Spiteri E, Stanley C, Szuto A, Taft RJ, Thiffault I, Thomas BC, Thomas-Wilson A, Thorpe E, Tidwell TJ, Towne MC, Zouk H; Medical Genome Initiative Steering Committee. Rehm HL, et al. Genet Med. 2023 Dec;25(12):100947. doi: 10.1016/j.gim.2023.100947. Epub 2023 Jul 30. Genet Med. 2023. PMID: 37534744 Free PMC article.
Neuronal somatic plasmalemmal permeability and dendritic beading caused by head rotational traumatic brain injury in pigs-An exploratory study.
Harris JP, Mietus CJ, Browne KD, Wofford KL, Keating CE, Brown DP, Johnson BN, Wolf JA, Smith DH, Cohen AS, Duda JE, Cullen DK. Harris JP, et al. Among authors: cohen as. Front Cell Neurosci. 2023 Jul 13;17:1055455. doi: 10.3389/fncel.2023.1055455. eCollection 2023. Front Cell Neurosci. 2023. PMID: 37519631 Free PMC article.
Direct haplotype-resolved 5-base HiFi sequencing for genome-wide profiling of hypermethylation outliers in a rare disease cohort.
Cheung WA, Johnson AF, Rowell WJ, Farrow E, Hall R, Cohen ASA, Means JC, Zion TN, Portik DM, Saunders CT, Koseva B, Bi C, Truong TK, Schwendinger-Schreck C, Yoo B, Johnston JJ, Gibson M, Evrony G, Rizzo WB, Thiffault I, Younger ST, Curran T, Wenger AM, Grundberg E, Pastinen T. Cheung WA, et al. Nat Commun. 2023 May 29;14(1):3090. doi: 10.1038/s41467-023-38782-1. Nat Commun. 2023. PMID: 37248219 Free PMC article.
Maintenance of a Lateral Fluid Percussion Injury Device.
Farrugia AM, Delcy SAS, Johnson BN, Cohen AS. Farrugia AM, et al. Among authors: cohen as. J Vis Exp. 2023 Apr 21;(194):10.3791/64678. doi: 10.3791/64678. J Vis Exp. 2023. PMID: 37154543 Free PMC article.
An Online Repository for Pre-Clinical Imaging Protocols (PIPs).
Gammon ST, Cohen AS, Lehnert AL, Sullivan DC, Malyarenko D, Manning HC, Hormuth DA, Daldrup-Link HE, An H, Quirk JD, Shoghi K, Pagel MD, Kinahan PE, Miyaoka RS, Houghton AM, Lewis MT, Larson P, Sriram R, Blocker SJ, Pickup S, Badea A, Badea CT, Yankeelov TE, Chenevert TL. Gammon ST, et al. Among authors: cohen as. Tomography. 2023 Mar 27;9(2):750-758. doi: 10.3390/tomography9020060. Tomography. 2023. PMID: 37104131 Free PMC article.
Inequities in Telemedicine Use Among Patients With Stroke and Cerebrovascular Diseases: A Tricenter Cross-sectional Study.
Naqvi IA, Cohen AS, Kim Y, Harris J, Denny MC, Strobino K, Bicher N, Leite RA, Sadowsky D, Adegboye C, Okpala N, Okpala M, Savitz SI, Marshall RS, Sharrief A. Naqvi IA, et al. Among authors: cohen as. Neurol Clin Pract. 2023 Apr;13(2):e200148. doi: 10.1212/CPJ.0000000000200148. Epub 2023 Mar 14. Neurol Clin Pract. 2023. PMID: 37064589 Free PMC article.
LHX2 haploinsufficiency causes a variable neurodevelopmental disorder.
Schmid CM, Gregor A, Costain G, Morel CF, Massingham L, Schwab J, Quélin C, Faoucher M, Kaplan J, Procopio R, Saunders CJ, Cohen ASA, Lemire G, Sacharow S, O'Donnell-Luria A, Segal RJ, Kianmahd Shamshoni J, Schweitzer D, Ebrahimi-Fakhari D, Monaghan K, Palculict TB, Napier MP, Tao A, Isidor B, Moradkhani K, Reis A, Sticht H; Care4Rare Canada; Chung WK, Zweier C. Schmid CM, et al. Genet Med. 2023 Jul;25(7):100839. doi: 10.1016/j.gim.2023.100839. Epub 2023 Apr 11. Genet Med. 2023. PMID: 37057675 Free article.
Rare variants in PPFIA3 cause delayed development, intellectual disability, autism, and epilepsy.
Paul MS, Michener SL, Pan H, Pfliger JM, Rosenfeld JA, Lerma VC, Tran A, Longley MA, Lewis RA, Weisz-Hubshman M, Bekheirnia MR, Bekheirnia N, Massingham L, Zech M, Wagner M, Engels H, Cremer K, Mangold E, Peters S, Trautmann J, Mester JL, Guillen Sacoto MJ, Person R, McDonnell PP, Cohen SR, Lusk L, Cohen ASA, Pichon JL, Pastinen T, Zhou D, Engleman K, Racine C, Faivre L, Moutton S, Pichon AD, Schuhmann S, Vasileiou G, Russ-Hall S, Scheffer IE, Carvill GL, Mefford H, Network UD, Bacino CA, Lee BH, Chao HT. Paul MS, et al. medRxiv [Preprint]. 2023 Mar 29:2023.03.27.23287689. doi: 10.1101/2023.03.27.23287689. medRxiv. 2023. PMID: 37034625 Free PMC article. Preprint.
Insurance denials and diagnostic rates in a pediatric genomic research cohort.
Zion TN, Berrios CD, Cohen ASA, Bartik L, Cross LA, Engleman KL, Fleming EA, Gadea RN, Hughes SS, Jenkins JL, Kussmann J, Lawson C, Schwager C, Strenk ME, Welsh H, Rush ET, Amudhavalli SM, Sullivan BR, Zhou D, Gannon JL, Heese BA, Moore R, Boillat E, Biswell RL, Louiselle DA, Puckett LMB, Beyer S, Neal SH, Sierant V, McBeth M, Belden B, Walter AM, Gibson M, Cheung WA, Johnston JJ, Thiffault I, Farrow EG, Grundberg E, Pastinen T. Zion TN, et al. Genet Med. 2023 May;25(5):100020. doi: 10.1016/j.gim.2023.100020. Epub 2023 Jan 28. Genet Med. 2023. PMID: 36718845 Free PMC article.
Remote Assessment of Negative Symptoms of Schizophrenia.
Daniel DG, Cohen AS, Velligan D, Harvey PD, Alphs L, Davidson M, Potter W, Kott A, Schooler N, Brodie CR, Moore RC, Lindenmeyer P, Marder SR. Daniel DG, et al. Among authors: cohen as. Schizophr Bull Open. 2023 Jan 26;4(1):sgad001. doi: 10.1093/schizbullopen/sgad001. eCollection 2023 Jan. Schizophr Bull Open. 2023. PMID: 39145343 Free PMC article. Review.
Hemodilution in pediatric trauma:  Defining the expected hemoglobin changes in patients with liver and/or spleen injury: An ATOMAC+ secondary analysis.
Stottlemyre RL, Notrica DM, Cohen AS, Sayrs LW, Naiditch J, St Peter SD, Leys CM, Ostlie DJ, Maxson RT, Ponsky T, Eubanks JW 3rd, Bhatia A, Greenwell C, Lawson KA, Alder AC, Johnson J, Garvey E. Stottlemyre RL, et al. Among authors: cohen as. J Pediatr Surg. 2023 Feb;58(2):325-329. doi: 10.1016/j.jpedsurg.2022.10.044. Epub 2022 Oct 23. J Pediatr Surg. 2023. PMID: 36428184
Pleistocene climate variability in eastern Africa influenced hominin evolution.
Foerster V, Asrat A, Bronk Ramsey C, Brown ET, Chapot MS, Deino A, Duesing W, Grove M, Hahn A, Junginger A, Kaboth-Bahr S, Lane CS, Opitz S, Noren A, Roberts HM, Stockhecke M, Tiedemann R, Vidal CM, Vogelsang R, Cohen AS, Lamb HF, Schaebitz F, Trauth MH. Foerster V, et al. Among authors: cohen as. Nat Geosci. 2022;15(10):805-811. doi: 10.1038/s41561-022-01032-y. Epub 2022 Sep 26. Nat Geosci. 2022. PMID: 36254302 Free PMC article.
Variants in the zinc transporter TMEM163 cause a hypomyelinating leukodystrophy.
do Rosario MC, Bey GR, Nmezi B, Liu F, Oranburg T, Cohen ASA, Coffman KA, Brown MR, Kiselyov K, Waisfisz Q, Flohil MT, Siddiqui S, Rosenfeld JA, Iglesias A, Girisha KM, Wolf NI, Padiath QS, Shukla A. do Rosario MC, et al. Brain. 2022 Dec 19;145(12):4202-4209. doi: 10.1093/brain/awac295. Brain. 2022. PMID: 35953447 Free PMC article.
Plio-Pleistocene environmental variability in Africa and its implications for mammalian evolution.
Cohen AS, Du A, Rowan J, Yost CL, Billingsley AL, Campisano CJ, Brown ET, Deino AL, Feibel CS, Grant K, Kingston JD, Lupien RL, Muiruri V, Owen RB, Reed KE, Russell J, Stockhecke M. Cohen AS, et al. Proc Natl Acad Sci U S A. 2022 Apr 19;119(16):e2107393119. doi: 10.1073/pnas.2107393119. Epub 2022 Apr 11. Proc Natl Acad Sci U S A. 2022. PMID: 35412903 Free PMC article.
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